{"id":26040,"date":"2021-05-03T11:13:53","date_gmt":"2021-05-03T15:13:53","guid":{"rendered":"https:\/\/labs.icahn.mssm.edu\/garcia-sastre\/?page_id=26040"},"modified":"2021-05-03T11:13:53","modified_gmt":"2021-05-03T15:13:53","slug":"rodrigo-canas-arranz-ph-d","status":"publish","type":"page","link":"https:\/\/labs.icahn.mssm.edu\/garcia-sastre\/rodrigo-canas-arranz-ph-d\/","title":{"rendered":"Rodrigo Canas-Arranz, Ph.D."},"content":{"rendered":"

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Postdoctoral Fellow
\n<\/em>rodrigo.canas.arranz@mssm.edu<\/a><\/p>\n

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Research Interests
\n<\/span><\/strong>Innate immune responses are the first barrier of defense against viral infections. The induction of type I and III IFN is a critical step to provide an antiviral state and limit viral replication in the host. My work focuses on the host immune response to viral infections. Specifically, type I and III IFN responses using\u00a0 in vitro and in vivo models as well as the role of certain IFN-stimulated genes to clear the infection against several viruses, including Influenza virus, SARS-CoV-2 or West Nile Virus. Understanding the mechanisms underlying these virus-host interactions, would allow identifying new antiviral targets and the development of vaccines<\/p>\n

Notable Publications
\n<\/strong><\/span>Canas-Arranz, R.<\/span><\/b>, P. de Leon, M. Forner, S. Defaus, M. J. Bustos, E. Torres, D. Andreu, E. Blanco, and F. Sobrino. 2020. ‘Immunogenicity of a Dendrimer B2T Peptide Harboring a T-Cell Epitope From FMDV Non-structural Protein 3D<\/a>‘, Front Vet Sci<\/i>, 7: 498.
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Canas-Arranz, R.<\/span><\/b>, M. Forner, S. Defaus, P. de Leon, M. J. Bustos, E. Torres, F. Sobrino, D. Andreu, and E. Blanco. 2020. ‘A Single Dose of Dendrimer B2T Peptide Vaccine Partially Protects<\/a>
\n<\/span>Pigs against Foot-and-Mouth Disease Virus Infection’, Vaccines (Basel)<\/i>, 8.
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Canas-Arranz, R.<\/span><\/b>, M. Forner, S. Defaus, M. Rodriguez-Pulido, P. de Leon, E. Torres, M. J. Bustos, B. Borrego, M. Saiz, E. Blanco, D. Andreu, and F. Sobrino. 2020. ‘A bivalent B-cell epitope dendrimer peptide can confer long-lasting immunity in swine against foot-and-mouth disease<\/a>‘, Transbound Emerg Dis<\/i>, 67: 1614-22.<\/span><\/p>\n

de Leon, P., R. Canas-Arranz<\/b>, S. Defaus, E. Torres, M. Forner, M. J. Bustos, C. Revilla, J. Dominguez, D. Andreu, E. Blanco, and F. Sobrino. 2020. ‘Swine T-Cells and Specific Antibodies Evoked by Peptide Dendrimers Displaying Different FMDV T-Cell Epitopes<\/a>‘, Front Immunol<\/i>, 11: 621537.<\/span><\/p>\n

de Leon, P., R. Canas-Arranz<\/b>, Y. Saez, M. Forner, S. Defaus, D. Cuadra, M. J. Bustos, E. Torres, D. Andreu, E. Blanco, F. Sobrino, and S. E. Hammer. 2020. ‘Association of Porcine Swine Leukocyte Antigen (SLA) Haplotypes with B- and T-Cell Immune Response to Foot-and-Mouth Disease Virus (FMDV) Peptides<\/a>‘, Vaccines (Basel)<\/i>, 8.<\/span><\/p>\n","protected":false},"excerpt":{"rendered":"

Postdoctoral Fellow rodrigo.canas.arranz@mssm.edu             Research Interests Innate immune responses are the first barrier of defense against viral infections. The induction of type I and III IFN is a critical step to provide an antiviral state and limit viral replication in the host. My work focuses on the host immune response […]<\/p>\n","protected":false},"author":36,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"footnotes":""},"class_list":["post-26040","page","type-page","status-publish","hentry"],"aioseo_notices":[],"_links":{"self":[{"href":"https:\/\/labs.icahn.mssm.edu\/garcia-sastre\/wp-json\/wp\/v2\/pages\/26040","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/labs.icahn.mssm.edu\/garcia-sastre\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/labs.icahn.mssm.edu\/garcia-sastre\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/labs.icahn.mssm.edu\/garcia-sastre\/wp-json\/wp\/v2\/users\/36"}],"replies":[{"embeddable":true,"href":"https:\/\/labs.icahn.mssm.edu\/garcia-sastre\/wp-json\/wp\/v2\/comments?post=26040"}],"version-history":[{"count":2,"href":"https:\/\/labs.icahn.mssm.edu\/garcia-sastre\/wp-json\/wp\/v2\/pages\/26040\/revisions"}],"predecessor-version":[{"id":26042,"href":"https:\/\/labs.icahn.mssm.edu\/garcia-sastre\/wp-json\/wp\/v2\/pages\/26040\/revisions\/26042"}],"wp:attachment":[{"href":"https:\/\/labs.icahn.mssm.edu\/garcia-sastre\/wp-json\/wp\/v2\/media?parent=26040"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}