{"id":1817,"date":"2019-08-01T15:08:00","date_gmt":"2019-08-01T19:08:00","guid":{"rendered":"http:\/\/labs.icahn.mssm.edu\/garcia-sastre\/?page_id=1817"},"modified":"2020-01-07T11:05:19","modified_gmt":"2020-01-07T16:05:19","slug":"sadaf-aslam","status":"publish","type":"page","link":"https:\/\/labs.icahn.mssm.edu\/garcia-sastre\/sadaf-aslam\/","title":{"rendered":"Sadaf Aslam"},"content":{"rendered":"

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Associate Researcher
\nsadaf.aslam@mssm.edu<\/a><\/em><\/p>\n

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Research Interests<\/strong><\/span><\/p>\n

My research focuses on developing an optimized backbone for influenza B virus for vaccine production. We are working on generating a backbone that can be used in combination with any influenza B hemagglutinin and neuraminidase to give high yields in eggs for vaccine production. I am also working on studying how influenza A virus NS1 protein interacts with phosphoinositide 3-kinase.<\/p>\n

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Notable Publications<\/strong><\/span><\/p>\n

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  1. Asthagiri Arunkumar, G., Ioannou, A., Wohlbold, T. J., Meade, P., Aslam, S<\/strong>., Amanat, F., Ayll\u00f3n, J., Garc\u00eda-Sastre, A., Krammer, F. (2019). Broadly Cross-Reactive, Nonneutralizing Antibodies against Influenza B Virus Hemagglutinin Demonstrate Effector Function-Dependent Protection against Lethal Viral Challenge in Mice<\/a>. Journal of virology<\/em>, 93<\/em>(6), e01696-18. doi:10.1128\/JVI.01696-18<\/li>\n
  2. Mu\u00f1oz-Moreno, R., Mart\u00ednez-Romer, C., Blanco-Melo, D., Forst, C.V., Nachbagauer, R., Benitez, A. A., Mena, I., Aslam, S.<\/strong>, Balasubramaniam, V., Lee, I., Panis, M., Ayll\u00f3n, J., Sachs, D., Parks, M.S., Krammer, F., Tenoever, B. R., Garc\u00eda-Sastre, A. (2019). Viral fitness landscapes in diverse host species reveal multiple evolutionary lines for the NS1 gene of influenza A viruses<\/a>. Cell Reports<\/em>, 29(12):3997-4009.e5. doi: 10.1016\/j.celrep.2019.11.070.<\/li>\n
  3. Chromikova, V., Tan, J., Aslam, S<\/strong>., Rajabhathor, A., Ayll\u00f3n, J., Garc\u00eda-Sastre, A., Salaun, B., Nachbagauer, R., Krammer, F. (2019). Activity of serum antibody in a hemagglutinin stalk based ADCC reporter assay correlates well with activity in a CD107a-based degranulation assay. (Accepted in Vaccines<\/em><\/strong>)<\/li>\n<\/ol>\n","protected":false},"excerpt":{"rendered":"

    Associate Researcher sadaf.aslam@mssm.edu             Research Interests My research focuses on developing an optimized backbone for influenza B virus for vaccine production. We are working on generating a backbone that can be used in combination with any influenza B hemagglutinin and neuraminidase to give high yields in eggs for vaccine production. […]<\/p>\n","protected":false},"author":36,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"footnotes":""},"class_list":["post-1817","page","type-page","status-publish","hentry"],"aioseo_notices":[],"_links":{"self":[{"href":"https:\/\/labs.icahn.mssm.edu\/garcia-sastre\/wp-json\/wp\/v2\/pages\/1817","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/labs.icahn.mssm.edu\/garcia-sastre\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/labs.icahn.mssm.edu\/garcia-sastre\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/labs.icahn.mssm.edu\/garcia-sastre\/wp-json\/wp\/v2\/users\/36"}],"replies":[{"embeddable":true,"href":"https:\/\/labs.icahn.mssm.edu\/garcia-sastre\/wp-json\/wp\/v2\/comments?post=1817"}],"version-history":[{"count":4,"href":"https:\/\/labs.icahn.mssm.edu\/garcia-sastre\/wp-json\/wp\/v2\/pages\/1817\/revisions"}],"predecessor-version":[{"id":1869,"href":"https:\/\/labs.icahn.mssm.edu\/garcia-sastre\/wp-json\/wp\/v2\/pages\/1817\/revisions\/1869"}],"wp:attachment":[{"href":"https:\/\/labs.icahn.mssm.edu\/garcia-sastre\/wp-json\/wp\/v2\/media?parent=1817"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}