Briana McGovern

Associate Researcher
briana.mcgovern@mssm.edu

 

 

 

 

 

 

Research Interests
My past research involved working on developing an intranigral rotenone model of Parkinson’s Disease for the study of the hypoxic ventilatory response. Here I have been investigating antiviral compounds on SARS-CoV-2 and influenza viruses using both cellular and animal models. My current work is moving toward focusing on the effects of various protein kinase inhibitors on SARS-CoV-2 infection.

 

Notable Publications

Tummino TA, Rezelj VV, Fischer B, Fischer A, O’Meara MJ, Monel B, Vallet T, White KM, Zhang Z, Alon A, Schadt H, O’Donnell HR, Lyu J, Rosales R, McGovern BL, Rathnasinghe R, Jangra S, Schotsaert M, Galarneau J, Krogan NJ, Urban L, Shokat KM, Kruse AC, García-Sastre A, Schwartz O, Moretti F, Vignuzzi M, Pognan F, Shoichet BK.  (2021). Drug-induced phospholipidosis confounds drug repurposing for SARS-CoV-2Science. DOI: 10.1126/science.abi4708.

White K, Esparza M, Liang J, Bhat P, Naidoo J, McGovern BL, Williams MA, Alabi BR, Shay J, Niederstrasser H, Posner B, García-Sastre A, Ready J, Fontoura BMA. (2021). Aryl Sulfonamide Inhibits Entry and Replication of Diverse Influenza Viruses via the Hemagglutinin Protein. J. Med. Chem. DOI: 10.1021/acs.jmedchem.1c00304.