[et_pb_section fb_built=”1″ admin_label=”Fullwidth Header – Background Title Description – no slider – Section 1″ module_class=”header-title-desciption-no-slider-section1″ _builder_version=”4.9.0″ _module_preset=”default” background_color=”rgba(0,174,239,0.09)” background_enable_color=”off” background_image=”https:\/\/labs.icahn.mssm.edu\/gallolab-new\/wp-content\/uploads\/sites\/572\/2022\/07\/ai-002-1.jpg” parallax=”on” custom_padding=”||||false|false” bottom_divider_style=”ramp2″ bottom_divider_color=”#FFFFFF” bottom_divider_height=”11vw” bottom_divider_arrangement=”above_content” saved_tabs=”all” locked=”off” collapsed=”off”][et_pb_row column_structure=”1_2,1_2″ _builder_version=”4.9.0″ _module_preset=”default” background_color=”RGBA(0,0,0,0)” border_color_all=”RGBA(0,0,0,0)” collapsed=”off”][et_pb_column type=”1_2″ _builder_version=”4.9.0″ _module_preset=”default” custom_padding=”10%||8vw||false|false” custom_padding_tablet=”0vw||0vw||true|false” custom_padding_phone=”” custom_padding_last_edited=”on|tablet”][et_pb_text admin_label=”Text – Title” _builder_version=”4.9.0″ _module_preset=”b3e3ff14-5f5c-4608-8ecf-1885ce3da7aa” header_font=”||||||||” header_text_color=”#FFFFFF” header_font_size=”48px” header_line_height=”60px” custom_margin=”||10px||false|false” header_font_size_tablet=”40px” header_font_size_phone=”24px” header_font_size_last_edited=”on|desktop”]<\/p>\n
[\/et_pb_text][et_pb_text admin_label=”Text – Description” _builder_version=”4.9.0″ _module_preset=”da86b6f0-f83c-4c7c-bdd8-3019777ddffe” text_font=”||||||||” text_text_color=”#FFFFFF” text_font_size=”20px” text_line_height=”32px” hover_enabled=”0″ text_font_size_tablet=”15px” text_font_size_phone=”14px” text_font_size_last_edited=”on|desktop” sticky_enabled=”0″]<\/p>\n
We have a number of ongoing projects, briefly described below.<\/p>\n
[\/et_pb_text][\/et_pb_column][et_pb_column type=”1_2″ _builder_version=”4.9.0″ _module_preset=”default” background_color=”RGBA(0,0,0,0)”][\/et_pb_column][\/et_pb_row][\/et_pb_section][et_pb_section fb_built=”1″ admin_label=”Section 27 – Two Column – Title Over Text Over Button Next to Image” module_class=”section27_two_column_title_over_txt_over_btn_next_to_img” _builder_version=”4.9.0″ _module_preset=”default” background_image=”https:\/\/labs.icahn.mssm.edu\/gallolab-new\/wp-content\/uploads\/sites\/572\/2022\/12\/9-alt.png” parallax=”on” parallax_method=”off” hover_enabled=”0″ locked=”off” collapsed=”off” sticky_enabled=”0″][et_pb_row column_structure=”1_2,1_2″ _builder_version=”4.9.0″ module_alignment=”center” custom_margin=”|||” custom_margin_tablet=”” custom_margin_phone=”” custom_margin_last_edited=”on|phone” custom_padding=”||150px|||” global_module=”3003″ collapsed=”off”][et_pb_column type=”1_2″ _builder_version=”3.25″ background_color_gradient_direction=”35deg” custom_padding=”|60px||” custom_padding__hover=”|||”][et_pb_text _builder_version=”4.9.0″ text_font=”||||||||” header_font=”||||||||” header_text_align=”left” header_text_color=”#2b2b2b” header_font_size=”36px” header_line_height=”1.3em” header_2_font=”|700|||||||” header_2_text_align=”left” header_2_text_color=”#2b2b2b” header_2_font_size=”36px” header_2_line_height=”1.5em” text_orientation=”center” module_alignment=”center” custom_margin=”||10px|” hover_enabled=”0″ sticky_enabled=”0″]<\/p>\n
[\/et_pb_text][et_pb_text _builder_version=”4.9.0″ text_font=”||||||||” text_text_color=”#141414″ text_line_height=”1.9em” header_font=”||||||||” header_2_font=”||||||||” module_alignment=”center” custom_margin=”||30px|” hover_enabled=”0″ sticky_enabled=”0″]<\/p>\n
We have implemented a systems-based PK\/PD-driven drug development strategy to identify the most active drug in brain tumor models. This approach utilizes in vitro assays such as metabolic stability, blood-brain barrier [BBB] permeability and cytotoxicity to screen compounds that may be further characterized for their mechanism of action in preclinical brain tumor models. These studies support the development of mechanistic PK\/PD models that we will scale from preclinical studies to virtual patients that can inform on which patients are likely to benefit from the drug and how to design early clinical trials.<\/p>\n
[\/et_pb_text][et_pb_button button_url=”https:\/\/labs.icahn.mssm.edu\/design\/option1-research” button_text=”Read More” _builder_version=”4.9.0″ _module_preset=”default” custom_button=”on” button_text_color=”#FFFFFF” button_bg_color=”#00AEEF” button_border_radius=”0px” box_shadow_style=”preset1″ locked=”off” disabled_on=”on|on|on” disabled=”on”][\/et_pb_button][\/et_pb_column][et_pb_column type=”1_2″ module_class=”imageallignment” _builder_version=”4.9.0″ background_color=”RGBA(0,0,0,0)” use_background_color_gradient=”on” background_color_gradient_start=”#00aeef” background_color_gradient_end=”#221f72″ background_color_gradient_direction=”115deg” custom_padding=”|||” custom_padding__hover=”|||” custom_css_main_element_last_edited=”on|desktop” custom_css_main_element_tablet=”margin-top:60px!important”][et_pb_image src=”https:\/\/labs.icahn.mssm.edu\/gallolab-new\/wp-content\/uploads\/sites\/572\/2022\/12\/Research-3-800×828-1.jpg” title_text=”Research-3-800×828″ align=”center” _builder_version=”4.9.0″ background_color=”#221F72″ custom_margin=”-40px|40px|40px|-40px|false|false” custom_margin_tablet=”” custom_margin_phone=”-40px|40px|40px|-40px|false|false” custom_margin_last_edited=”on|phone” custom_padding=”|||” animation_style=”zoom” animation_direction=”right” animation_intensity_zoom=”6%” animation_starting_opacity=”100%” always_center_on_mobile=”off”][\/et_pb_image][\/et_pb_column][\/et_pb_row][et_pb_row column_structure=”1_2,1_2″ make_equal=”on” _builder_version=”4.9.0″ module_alignment=”center” custom_margin=”|auto|150px|auto||” custom_padding=”0px||0px|” hover_enabled=”0″ global_module=”3004″ collapsed=”off” sticky_enabled=”0″ locked=”off” saved_tabs=”all”][et_pb_column type=”1_2″ _builder_version=”4.9.0″ background_color=”#00AEEF” use_background_color_gradient=”on” background_color_gradient_start=”#00aeef” background_color_gradient_end=”#d80b8c” background_color_gradient_direction=”33deg” background_enable_image=”off” parallax=”on” custom_padding=”|5%||5%” hover_enabled=”0″ custom_padding__hover=”|||” sticky_enabled=”0″][et_pb_image src=”https:\/\/labs.icahn.mssm.edu\/gallolab-new\/wp-content\/uploads\/sites\/572\/2022\/12\/Research-1-800×1129-1.jpg” title_text=”Research-1-800×1129″ align=”center” align_tablet=”center” align_phone=”” align_last_edited=”on|desktop” _builder_version=”4.9.0″ custom_margin=”-20px||-20px|” custom_padding=”|||” animation_style=”zoom” animation_direction=”left” animation_intensity_zoom=”10%” animation_starting_opacity=”100%” hover_enabled=”0″ sticky_enabled=”0″][\/et_pb_image][\/et_pb_column][et_pb_column type=”1_2″ _builder_version=”3.25″ custom_padding=”40px|40px|40px|40px” custom_padding__hover=”|||”][et_pb_text _builder_version=”4.9.0″ header_font=”|700|||||||” header_font_size=”36px” header_3_font=”Playfair Display|700|||||||” header_3_text_color=”#2b2b2b” header_3_font_size=”28px” header_3_line_height=”1.5em” custom_margin=”||10px|” hover_enabled=”0″ sticky_enabled=”0″]<\/p>\n
[\/et_pb_text][et_pb_text _builder_version=”4.9.0″ text_font=”||||||||” text_text_color=”#141414″ text_line_height=”1.9em” header_font=”||||||||” header_2_font=”||||||||” module_alignment=”center” custom_margin=”||30px|” hover_enabled=”0″ sticky_enabled=”0″]<\/p>\n
There is an increasing appreciation that tumors are heterogeneous in terms of their genomic and proteomic characteristics that will likely impact drug efficacy. We are developing methods to determine the regional variability in the PK\/PD of anticancer drugs in brain tumors. One approach we have developed is referred to as cell-type specific PK\/PD models that are based on linking PK and PD intracellularly at the molecular level. Since these models can contrast drug action and toxicity in different cell types they offer a means to account for tumor heterogeneity and provide novel ways to assess and design drug therapy.<\/p>\n
[\/et_pb_text][et_pb_button button_url=”https:\/\/labs.icahn.mssm.edu\/design\/option1-research” button_text=”Read More” _builder_version=”4.9.0″ _module_preset=”default” custom_button=”on” button_text_color=”#FFFFFF” button_bg_color=”#00AEEF” button_border_radius=”0px” box_shadow_style=”preset1″ locked=”off” disabled_on=”on|on|on” disabled=”on”][\/et_pb_button][\/et_pb_column][\/et_pb_row][et_pb_row column_structure=”1_2,1_2″ make_equal=”on” _builder_version=”4.9.0″ module_alignment=”center” custom_margin=”||200px|” custom_padding=”0px|0px|0px|0px” global_module=”3005″ collapsed=”on” saved_tabs=”all”][et_pb_column type=”1_2″ _builder_version=”3.25″ background_color_gradient_direction=”35deg” custom_padding=”40px|40px|40px|40px” custom_padding__hover=”|||”][et_pb_text _builder_version=”4.9.0″ header_font=”||||||||” header_3_font=”Playfair Display|700|||||||” header_3_text_color=”#2b2b2b” header_3_font_size=”28px” header_3_line_height=”1.5em” custom_margin=”||10px|” hover_enabled=”0″ sticky_enabled=”0″]<\/p>\n
[\/et_pb_text][et_pb_text _builder_version=”4.9.0″ text_font=”||||||||” text_text_color=”#141414″ text_line_height=”1.9em” header_font=”||||||||” header_2_font=”||||||||” module_alignment=”center” custom_margin=”||30px|” hover_enabled=”0″ sticky_enabled=”0″]<\/p>\n
Many brain tumors possess a mutant isocitrate dehydrogenase [mIDH1] enzyme that produces an oncometabolite, D-2-hydroxyglutarate [D2HG]. We are evaluating the CNS disposition of mIDH1 inhibitors and D-2HG to determine optimal means to suppress 2HG and to combine these enzyme inhibitors with other drugs.\u00a0<\/p>\n
[\/et_pb_text][et_pb_button button_url=”https:\/\/labs.icahn.mssm.edu\/design\/option1-research” button_text=”Read More” _builder_version=”4.9.0″ _module_preset=”default” custom_button=”on” button_text_color=”#FFFFFF” button_bg_color=”#00AEEF” button_border_radius=”0px” box_shadow_style=”preset1″ locked=”off” disabled_on=”on|on|on” disabled=”on”][\/et_pb_button][\/et_pb_column][et_pb_column type=”1_2″ _builder_version=”4.9.0″ background_color=”#00AEEF” use_background_color_gradient=”on” background_color_gradient_start=”#221f72″ background_color_gradient_end=”#d80b8c” background_color_gradient_direction=”33deg” background_enable_image=”off” parallax=”on” custom_padding=”|5%||5%” custom_padding__hover=”|||”][et_pb_image src=”https:\/\/labs.icahn.mssm.edu\/gallolab-new\/wp-content\/uploads\/sites\/572\/2022\/12\/Research-2-800×977-1.jpg” title_text=”Research-2-800×977″ align=”center” align_tablet=”center” align_phone=”” align_last_edited=”on|desktop” _builder_version=”4.9.0″ custom_margin=”-20px||-20px|” custom_padding=”|||” animation_style=”zoom” animation_direction=”right” animation_intensity_zoom=”10%” animation_starting_opacity=”100%”][\/et_pb_image][\/et_pb_column][\/et_pb_row][et_pb_row _builder_version=”4.9.0″ _module_preset=”default” column_structure=”1_2,1_2″ make_equal=”on” module_alignment=”center” custom_margin=”|auto|150px|auto|false|false” custom_padding=”0px||0px||false|false” hover_enabled=”0″ sticky_enabled=”0″ background_enable_color=”off”][et_pb_column _builder_version=”4.9.0″ _module_preset=”default” type=”1_2″ hover_enabled=”0″ sticky_enabled=”0″ background_enable_color=”off”][et_pb_image src=”https:\/\/labs.icahn.mssm.edu\/gallolab-new\/wp-content\/uploads\/sites\/572\/2022\/12\/Research-1-800×1129-1.jpg” title_text=”Research-1-800×1129″ align=”center” align_tablet=”center” align_phone=”” align_last_edited=”on|desktop” _builder_version=”4.9.0″ custom_margin=”-20px||-20px|” custom_padding=”|||” animation_style=”zoom” animation_direction=”left” animation_intensity_zoom=”10%” animation_starting_opacity=”100%” hover_enabled=”0″ sticky_enabled=”0″ background_color=”#00AEEF” use_background_color_gradient=”on” background_color_gradient_end=”#d80b8c”][\/et_pb_image][\/et_pb_column][et_pb_column _builder_version=”4.9.0″ _module_preset=”default” type=”1_2″ hover_enabled=”0″ sticky_enabled=”0″ background_enable_color=”off”][et_pb_text _builder_version=”4.9.0″ _module_preset=”default” hover_enabled=”0″ sticky_enabled=”0″]<\/p>\n
[\/et_pb_text][et_pb_text _builder_version=”4.9.0″ _module_preset=”default” hover_enabled=”0″ sticky_enabled=”0″]<\/p>\n
Epigenetic mechanisms are an important determinant of gene and protein expression that has generated numerous efforts to design and develop drugs known under the umbrella of epigenetic modulators. We are interested in drugs able to inhibit histone demethylase enzymes in brain tumors.<\/p>\n
[\/et_pb_text][et_pb_button _builder_version=”4.9.0″ _module_preset=”default” hover_enabled=”0″ sticky_enabled=”0″ disabled_on=”on|on|on” disabled=”on”][\/et_pb_button][\/et_pb_column][\/et_pb_row][\/et_pb_section][et_pb_section fb_built=”1″ disabled_on=”on|on|on” admin_label=”Footer – Section 13″ module_class=”footer-section” _builder_version=”4.9.0″ background_color=”#c7eafb” background_image=”https:\/\/labs.icahn.mssm.edu\/gallolab-new\/wp-content\/uploads\/sites\/572\/2022\/10\/Rectangle-3.png” max_width=”80%” max_width_tablet=”” max_width_phone=”” max_width_last_edited=”on|phone” module_alignment=”center” custom_margin=”100px|||176px|false|false” custom_padding=”3px|0px|40px|0px||” animation_style=”slide” animation_direction=”bottom” animation_intensity_slide=”14%” animation_starting_opacity=”100%” disabled=”on” global_module=”425″ saved_tabs=”all” locked=”off” collapsed=”on”][et_pb_row _builder_version=”4.9.0″ background_color=”RGBA(0,0,0,0)” background_color_gradient_direction=”38deg” module_alignment=”center” custom_margin=”|auto||147px||” locked=”off”][et_pb_column type=”4_4″ _builder_version=”3.25″ custom_padding=”|||” custom_padding__hover=”|||”][et_pb_social_media_follow _builder_version=”4.9.0″ _module_preset=”default” background_color=”RGBA(0,0,0,0)” text_orientation=”center”][et_pb_social_media_follow_network social_network=”linkedin” url=”https:\/\/www.linkedin.com\/school\/icahnmountsinai\/%20″ use_icon_font_size=”on” icon_font_size=”24px” _builder_version=”4.9.0″ _module_preset=”default” background_color=”RGBA(0,0,0,0)” background_enable_color=”on”]linkedin[\/et_pb_social_media_follow_network][et_pb_social_media_follow_network social_network=”facebook” url=”https:\/\/www.facebook.com\/IcahnMountSinai” use_icon_font_size=”on” icon_font_size=”24px” _builder_version=”4.9.0″ _module_preset=”default” background_color=”RGBA(0,0,0,0)” background_enable_color=”on”]facebook[\/et_pb_social_media_follow_network][et_pb_social_media_follow_network social_network=”twitter” url=”https:\/\/twitter.com\/icahnmountsinai” use_icon_font_size=”on” icon_font_size=”24px” _builder_version=”4.9.0″ _module_preset=”default” background_color=”RGBA(0,0,0,0)” background_enable_color=”on”]twitter[\/et_pb_social_media_follow_network][et_pb_social_media_follow_network social_network=”youtube” url=”https:\/\/www.youtube.com\/user\/MountSinaiSchool” use_icon_font_size=”on” icon_font_size=”24px” _builder_version=”4.9.0″ _module_preset=”default” background_color=”RGBA(0,0,0,0)” background_enable_color=”on”]youtube[\/et_pb_social_media_follow_network][et_pb_social_media_follow_network social_network=”instagram” url=”https:\/\/www.instagram.com\/icahnmountsinai\/” use_icon_font_size=”on” icon_font_size=”24px” _builder_version=”4.9.0″ _module_preset=”default” background_color=”RGBA(0,0,0,0)” background_enable_color=”on”]instagram[\/et_pb_social_media_follow_network][\/et_pb_social_media_follow][et_pb_text _builder_version=”4.9.0″ _module_preset=”default” text_text_color=”#FFFFFF” text_font_size=”24px”]<\/p>\n
Contact Us<\/strong><\/p>\n [\/et_pb_text][\/et_pb_column][\/et_pb_row][et_pb_row column_structure=”1_3,1_3,1_3″ _builder_version=”4.9.0″ background_color=”RGBA(0,0,0,0)” background_color_gradient_direction=”38deg” module_alignment=”center” custom_margin=”|auto|-2px|auto||” custom_padding=”0px|||||” locked=”off”][et_pb_column type=”1_3″ _builder_version=”4.9.0″ custom_padding=”|||” custom_padding__hover=”|||”][et_pb_text _builder_version=”4.9.0″ _module_preset=”default” text_font=”||||||||” text_text_color=”#FFFFFF” text_line_height=”22px”]<\/p>\n Contact Us [\/et_pb_text][\/et_pb_column][et_pb_column type=”1_3″ _builder_version=”3.25″ custom_padding=”|||” custom_padding__hover=”|||”][et_pb_text _builder_version=”4.9.0″ text_font=”||||||||” text_text_color=”#FFFFFF” text_line_height=”1.25em” header_font=”||||||||” header_4_font=”|700||on|||||” header_4_font_size=”16px” header_4_letter_spacing=”1px” header_4_line_height=”1.5em” background_layout=”dark” locked=”off”]<\/p>\n E-mail Phone [\/et_pb_text][\/et_pb_column][et_pb_column type=”1_3″ _builder_version=”3.25″ custom_padding=”|||” custom_padding__hover=”|||”][et_pb_text _builder_version=”4.9.0″ text_font=”||||||||” text_text_color=”#FFFFFF” text_line_height=”1.25em” header_font=”||||||||” header_4_font=”|700||on|||||” header_4_font_size=”16px” header_4_letter_spacing=”1px” header_4_line_height=”1.5em” background_layout=”dark” locked=”off”]<\/p>\n Lab Address <\/strong> Mailing Address <\/strong><\/p>\n Lab Name [\/et_pb_text][\/et_pb_column][\/et_pb_row][\/et_pb_section][et_pb_section fb_built=”1″ disabled_on=”off|off|off” admin_label=”Footer Fullwidth – Section 13″ module_class=”footer-section” _builder_version=”4.9.0″ background_color=”#c7eafb” background_image=”https:\/\/labs.icahn.mssm.edu\/gallolab-new\/wp-content\/uploads\/sites\/572\/2022\/10\/Rectangle-3.png” max_width=”100%” max_width_tablet=”” max_width_phone=”” max_width_last_edited=”on|phone” module_alignment=”center” 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background_color=”RGBA(0,0,0,0)” background_enable_color=”on” follow_button=”off” url_new_window=”on”]linkedin[\/et_pb_social_media_follow_network][et_pb_social_media_follow_network social_network=”facebook” url=”https:\/\/www.facebook.com\/IcahnMountSinai” use_icon_font_size=”on” icon_font_size=”24px” _builder_version=”4.9.0″ _module_preset=”default” background_color=”RGBA(0,0,0,0)” background_enable_color=”on” follow_button=”off” url_new_window=”on”]facebook[\/et_pb_social_media_follow_network][et_pb_social_media_follow_network social_network=”twitter” url=”https:\/\/twitter.com\/icahnmountsinai” use_icon_font_size=”on” icon_font_size=”24px” _builder_version=”4.9.0″ _module_preset=”default” background_color=”RGBA(0,0,0,0)” background_enable_color=”on” follow_button=”off” url_new_window=”on”]twitter[\/et_pb_social_media_follow_network][et_pb_social_media_follow_network social_network=”youtube” url=”https:\/\/www.youtube.com\/user\/MountSinaiSchool” use_icon_font_size=”on” icon_font_size=”24px” _builder_version=”4.9.0″ _module_preset=”default” background_color=”RGBA(0,0,0,0)” background_enable_color=”on” follow_button=”off” url_new_window=”on”]youtube[\/et_pb_social_media_follow_network][et_pb_social_media_follow_network social_network=”instagram” url=”https:\/\/www.instagram.com\/icahnmountsinai\/” use_icon_font_size=”on” icon_font_size=”24px” _builder_version=”4.9.0″ _module_preset=”default” background_color=”RGBA(0,0,0,0)” background_enable_color=”on” follow_button=”off” url_new_window=”on”]instagram[\/et_pb_social_media_follow_network][\/et_pb_social_media_follow][et_pb_text _builder_version=”4.9.0″ _module_preset=”default” text_text_color=”#FFFFFF” text_font_size=”24px”]<\/p>\n Contact Us<\/strong><\/p>\n [\/et_pb_text][\/et_pb_column][\/et_pb_row][et_pb_row column_structure=”1_3,1_3,1_3″ _builder_version=”4.9.0″ background_color=”RGBA(0,0,0,0)” background_color_gradient_direction=”38deg” module_alignment=”center” custom_margin=”|auto|-2px|auto||” custom_padding=”0px|||||” locked=”off” collapsed=”off”][et_pb_column type=”1_3″ _builder_version=”4.9.0″ custom_padding=”|||” custom_padding__hover=”|||”][et_pb_text disabled_on=”on|on|on” _builder_version=”4.9.0″ _module_preset=”default” text_font=”||||||||” text_text_color=”#FFFFFF” text_line_height=”22px” disabled=”on”]<\/p>\n Contact Us [\/et_pb_text][\/et_pb_column][et_pb_column type=”1_3″ _builder_version=”3.25″ custom_padding=”|||” custom_padding__hover=”|||”][et_pb_text _builder_version=”4.9.0″ text_font=”||||||||” text_text_color=”#FFFFFF” text_line_height=”1.25em” header_font=”||||||||” header_4_font=”|700||on|||||” header_4_font_size=”16px” header_4_letter_spacing=”1px” header_4_line_height=”1.5em” background_layout=”dark” locked=”off”]<\/p>\n E-mail Phone [\/et_pb_text][\/et_pb_column][et_pb_column type=”1_3″ _builder_version=”3.25″ custom_padding=”|||” custom_padding__hover=”|||”][et_pb_text _builder_version=”4.9.0″ text_font=”||||||||” text_text_color=”#FFFFFF” text_line_height=”1.25em” header_font=”||||||||” header_4_font=”|700||on|||||” header_4_font_size=”16px” header_4_letter_spacing=”1px” header_4_line_height=”1.5em” background_layout=”dark” locked=”off”]<\/p>\n Lab Address <\/strong> Office Location<\/strong> Mailing Address <\/strong><\/p>\n Icahn School of Medicine at Mount Sinai [\/et_pb_text][\/et_pb_column][\/et_pb_row][\/et_pb_section]<\/p>\n","protected":false},"excerpt":{"rendered":" ResearchWe have a number of ongoing projects, briefly described below.Project 1: Drug Development of Anticancer Drugs for Brain Tumor ChemotherapyWe have implemented a systems-based PK\/PD-driven drug development strategy to identify the most active drug in brain tumor models. This approach utilizes in vitro assays such as metabolic stability, blood-brain barrier [BBB] permeability and cytotoxicity to […]<\/p>\n","protected":false},"author":545,"featured_media":0,"parent":0,"menu_order":3,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_et_pb_use_builder":"on","_et_pb_old_content":"","_et_gb_content_width":"","inline_featured_image":false,"footnotes":""},"class_list":["post-3010","page","type-page","status-publish","hentry"],"aioseo_notices":[],"_links":{"self":[{"href":"https:\/\/labs.icahn.mssm.edu\/gallolab\/wp-json\/wp\/v2\/pages\/3010","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/labs.icahn.mssm.edu\/gallolab\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/labs.icahn.mssm.edu\/gallolab\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/labs.icahn.mssm.edu\/gallolab\/wp-json\/wp\/v2\/users\/545"}],"replies":[{"embeddable":true,"href":"https:\/\/labs.icahn.mssm.edu\/gallolab\/wp-json\/wp\/v2\/comments?post=3010"}],"version-history":[{"count":5,"href":"https:\/\/labs.icahn.mssm.edu\/gallolab\/wp-json\/wp\/v2\/pages\/3010\/revisions"}],"predecessor-version":[{"id":4487,"href":"https:\/\/labs.icahn.mssm.edu\/gallolab\/wp-json\/wp\/v2\/pages\/3010\/revisions\/4487"}],"wp:attachment":[{"href":"https:\/\/labs.icahn.mssm.edu\/gallolab\/wp-json\/wp\/v2\/media?parent=3010"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}
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Icahn School of Medicine
at Mount Sinai
One Gustave L. Levy Place
<\/span>Annenberg
<\/span>New York, NY 10029<\/span><\/p>\n
<\/a><\/span>Recent News
<\/a>Alumni
<\/a>Researchers
<\/a>Gallery
<\/a>Resources
<\/a>Submit Inquiry
<\/a>Resources
<\/a>Lab Trials
Accessibility<\/a><\/span><\/p>\n
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<\/strong>Tel: 212-241-7770
Fx: 212-996-7214<\/p>\n
Annenberg Building
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Floor 19 Room 19-40
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James Gallo, PhD
Annenberg Building
1468 Madison Ave
Floor 19 Room 19-40A
New York, NY 10029<\/p>\n
Department of Pharmacology and Systems Therapeutics
One Gustave L. Levy Place
<\/span>Box 1603
<\/span>New York, NY 10029<\/span><\/p>\n