Publications

2025

Da Silva Bortoleti BT, Quasem S, Maurer S, Zhong X, Pimenta R, Ribeiro de Lima Brandão L, Hernandez M, Fraidenburg M, Alves da Silva PH, Alvarez R, Chen BK, Diniz MA, Housman B, Flores RM, Brody R, Marron TU, Ferrari de Andrade L*. A monoclonal antibody that inhibits the shedding of CD16a and CD16b and promotes antibody-dependent cellular cytotoxicity against tumors. Nature Communications 2025 Nov 11;16(1):9915. *Corresponding author.

2024

Tahri S, Piccinelli S, Su NK, Lampe L, Dong H, Vergara Cadavid J, Boiarsky R, Papazian N, Lightbody ED, Cao A, Alberge JB, Ferrari de Andrade L, Rahmat M, Shen Y, Blanco Fernández L, Zabaleta A, Günther A, Getz G, Sonneveld P, Cupedo T, Wucherpfennig KW, Ghobrial IM, Romee R. Inhibition of MICA and MICB shedding enhances memory-like NK-cell-mediated cytotoxicity against multiple myeloma. Blood Advances 2024, 8(20):5365-5370

2023

Goulding J, Yeh WI, Hancock B, Blum R, Xu T, Yang BH, Chang CW, Groff B, Avramis E, Pribadi M, Pan Y, Chu HY, Sikaroodi S, Fong L, Brookhouser N, Dailey T, Meza M, Denholtz M, Diaz E, Martin J, Szabo P, Cooley S, Ferrari de Andrade L, Lee TT, Bjordahl R, Wucherpfennig KW, Valamehr B. A chimeric antigen receptor uniquely recognizing MICA/B stress proteins provides an effective approach to target solid tumors. Med 2023 Jul 14;4(7):457-477.e8.

Park MD, Reyes-Torres I, LeBerichel J, Hamon P, LaMarche NM, Hegde S, Belabed M, Troncoso L, Grout JA, Magen A, Humblin E, Nair A, Molgora M, Hou J, Newman JH, Farkas AM, Leader AM, Dawson T, D’Souza D, Hamel S, Sanchez-Paulete AR, Maier B, Bhardwaj N, Martin JC, Kamphorst AO, Kenigsberg E, Casanova-Acebes M, Horowitz A, Brown BD, Ferrari de Andrade L, Colonna M, Marron TU, Merad M. TREM2 macrophages drive NK cell paucity and dysfunction in lung cancer. Nature Immunology 2023 May;24(5):792-801.

2022

Alves da Silva, PH; Xing, S; Kotini, AG; Papapetrou, EP; Song, X; Wucherpfennig, KW, Mascarenhas J; Ferrari de Andrade, L*. MICA/B antibody induces macrophage-mediated immunity against acute myeloid leukemia. Blood 139(2):205-216, 2022. PMID: 34359073. *Corresponding author.

Maurer, S; Zhong, X; Prada, BD; Mascarenhas, J; Ferrari de Andrade, L.* The Latest Breakthroughs in Immunotherapy for Acute Myeloid Leukemia, with a Special Focus on NKG2D Ligands. International Journal of Molecular Sciences 2022, 23(24), 15,907. PMID: 36555547. *Corresponding author.

2020

Xing, S; Ferrari de Andrade, L*. NKG2D and MICA/B shedding: a ‘tag game’ between NK cells and malignant cells. Clinical & Translational Immunology 9(12), e1230, 2020. PMID: 33363734. *Corresponding author.

Maurer, S*; Ferrari de Andrade, L*. NK cell interaction with platelets and myeloid cells in the tumor milieu. Frontiers in Immunology 11, Article 608849, 2020. PMID: 33424862. *Corresponding authors.

Ferrari de Andrade, L*; Kumar, S; Luoma, AM; Ito, Y; Alves da Silva, PH; Pan, D; Pyrdol, JW; Yoon, CH; Wucherpfennig, KW.* Inhibition of MICA and MICB Shedding Elicits NK cell-mediated Immunity against Tumors Resistant to Cytotoxic T cells. Cancer Immunology Research 8:769-780, 2020. PMID: 32209637. *Corresponding authors.

2019

Ferrari de Andrade, L*; Lu, Y*; Luoma, A; Ito, Y; Pan, D; Pyrdol, JW; Yoon, CH; Yuan, G-C; Wucherpfennig, KW. Discovery of specialized NK cell populations infiltrating human melanoma metastases. JCI Insight 2019;4(23):e133103. PMID: 31801909. *Equal authorship.

2018

Ferrari de Andrade, L; Tay, RE; Pan, D; Luoma, AM; Ito, Y; Badrinath, S; Tsoucas, D; Franz, B; May Jr KF; Harvey, CJ; Kobold, S; Pyrdol, JW; Yoon, C; Yuan, G-C; Hodi, FS; Dranoff, G; Wucherpfennig, KW. Antibody-Mediated Inhibition of MICA/B Shedding Promotes NK Cell-Driven Tumor Immunity. Science 359, 1537-1542, 2018. PMID: 29599246.

2015

Guillerey, C*; Ferrari de Andrade, L*; Vuckovic, S; Miles, K; Ngiow, SF; Yong, MCR; Teng, MWL; Colonna, M; Ritchie, DS; Chesi, M; Bergsagel, PL; Hill, GR; Smyth, MJ; and Martinet, L. Immunosurveillance and therapy of multiple myeloma are CD226 dependent. The Journal of Clinical Investigation 125(5), 2077-2089, 2015. PMID: 26075821. *Equal authorship.

2014

Ferrari de Andrade, L; Ngiow, SF; Stannard, K; Rusakiewicz, S; Kalimutho, M; Khanna, KK; Tey, S-K; Takeda, K; Zitvogel, L; Martinet, L; and Smyth, MJ. NK cells are essential for the ability of BRAF inhibitors to control BRAFV600E-mutant metastatic melanoma. Cancer Research 74(24), 7298-7308, 2014. PMID: 25351955.

Ferrari de Andrade, L; Smyth MJ; and Martinet L. DNAM-1 control of natural killer cells functions through nectin and nectin-like proteins. Immunology and Cell Biology 92, 237-244, 2014. PMID: 24343663.