Publications

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A complete Pubmed list of the publications by the Fernandez-Sesma group can be found in this link:

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  1. Challenges on the development of a dengue vaccine: a comprehensive review of the state of the art. Pintado Silva J, Fernandez-Sesma A. Challenges on the development of a dengue vaccine: a comprehensive review of the state of the art. J Gen Virol. 2023 Mar;104(3):001831. doi: 10.1099/jgv.0.001831. PMID: 36857199; PMCID: PMC10228381.
  2. The dengue virus 4 component of NIAID’s tetravalent TV003 vaccine drives its innate immune signature. Pintado Silva J, Fenutria R, Bernal-Rubio D, Sanchez-Martin I, Hunziker A, Chebishev E, Veloz J, Kelly G, Kim-Schulze S, Whitehead S, Durbin A, Ramos I, Fernandez-Sesma A. 2022. Exp Biol Med (Maywood). 2022 Dec;247(24):2201-2212. doi: 10.1177/15353702231151241. PMID: 36734144; PMCID: PMC9899989
  3. Chikungunya virus antagonizes cGAS-STING mediated type-I interferon responses by degrading cGAS. Webb, L.G., Veloz, J., Pintado-Silva, J. Zhu, T., Rangel, M., Mutetwa, T., Bernal-Rubio, D., Figueroa, D., Carrau, L., Fenutria, R., Potla, U., Reid, St.P, Yount, J., Stapleford, K., Aguirre, S., and A. Fernandez-Sesma. 2020. PLoS Pathog. 2020 Oct 15;16(10):e1008999. doi: 10.1371/journal.ppat.1008999.  eCollection 2020
  4. Innate immune antagonist function and cellular localization dynamics of human and avian IAV NS1 proteins in human Dendritic Cells. Lopez-Monteagudo, P., Munoz, R., Potla, U., Mena, I., Aydillo, T., Ayllon, J., Garcia-Sastre, A., J. Fribourg, M., Ramos, I and A. Fernandez-Sesma. 2019. Oct 9. Dec 12;94(1). pii: JVI.00999-19. doi: 10.1128/JVI.00999-19. [Epub ahead of print] PMID:31597767
  5. Innate immune response to influenza virus at single-cell resolution in human epithelial cells revealed paracrine induction of interferon lambda 1. Ramos, I., Smith, G., Ruf-zamojski, F., Martinez-Romero, C., Freiburg, M., Carbajal, E.A., Hartmann, B.M., Nair, V.D., Marjanovic, N., Lopez- Monteagudo,P., DeJesus, V.A., Mutetwa, T., Zamojski, M., Tan, G.S., Jayaprakash, C.,  Zaslavsky, E., Albrecht, R.A., Sealfon, S., Garcia-Sastre, A., and A. Fernandez-Sesma. 2019. Journal of Virology, 2019 Aug 2. pii: JVI.00559-19. doi: 10.1128/JVI.00559-19. [Epub ahead of print] PMID:31375585
  6. Dengue virus NS2B protein  targets cGAS for degradation preventing mtDNA sensing during infection. Aguirre, S., Luthra, P., Sanchez, M.T., Maestre, A.M., Patel, J., Lamothe, F. Fredericks, A., Tripathi, S., Zhu, T., Pintado-Silva, J., Webb, L.G., Bernal-Rubio, Solovyov, A., Greenbaum, B., Simon, V., Basler, C.F., D., Mulder, L., Garcia-Sastre, A. and A. Fernandez-Sesma. 2017.  Nature Microbiology, Mar 27;2:17037. doi: 10.1038/nmicrobiol.2017.37. PMC28346446
  7. High-dimensional CyTOF analysis of dengue virus–infected human DCs reveals distinct viral signatures. Hamlin, R., Rahman, A., Pak, T., Maringer, K., Mena, I., Bernal, D., Potla, U. Maestre, A., Fredericks, A., El-AD, A., Kasarskis, A., Ramos, I., Merad, M., and A. Fernandez-Sesma. 2017. JCIInsight 2017 Jul 6;2(13). doi: 10.1172/jci.insight.92424 [Epub ahead of print]. PMC5499363
  8. DENV inhibits type I IFN production in infected cells by cleaving human STING. Aguirre, S., Maestre, AM., Pagni, S., Patel, J., Savage, T.,  Gutman, D., Maringer, K., Bernal-Rubio, D., Shabman, R.S., Simon, V. Rodriguez-Madoz, JR., Mulder, LCF., Barber, GN, and A. Fernandez-Sesma. 2012. PLoS Pathog 2012 Oct; 8((10)): e1002934doi: 10.1371/journal.ppat.1002934. Epub 2012 Oct PMC3464218\
  9. Inhibition of Type I IFN Response in Human Dendritic Cells by Dengue Virus Infection Requires Catalytically Active NS2B3 Complex. Rodriguez-Madoz, J.R., Belicha-Villanueva, A. Bernal-Rubio, D., Ashour, J., Ayllon, J., and.  A. Fernandez-Sesma. 2010. J Virol, Oct;84(19):9760-9774. PMC2937777
  10. Interferon-b Pretreatment of Conventional and Plasmacytoid Human Dendritic Cells Enhances their Activation by Influenza Virus. Phipps-Yonas, H., Seto, J., Sealfon, S.C., Moran,T.M. and A. Fernandez-Sesma. 2008. PLoS Pathog, Oct;4(10): e1000193. (Epub 2008 Oct 31). PMC2568957.
  11. Type I IFN modulates innate and specific antiviral immunity. Durbin, J.E., Fernandez-Sesma, A., Lee, C-K., Rao, T.D., Frey, A.B., Moran, T.M.,Vukmanovic, S., Garcia-sastre, A., and D.E. Levy. 2000.  J Immunol., 164:4220-4228. PMID:10754318