{"id":2494,"date":"2022-12-20T11:44:55","date_gmt":"2022-12-20T16:44:55","guid":{"rendered":"https:\/\/labs.icahn.mssm.edu\/design\/?page_id=2494"},"modified":"2025-04-30T09:07:32","modified_gmt":"2025-04-30T13:07:32","slug":"publications","status":"publish","type":"page","link":"https:\/\/labs.icahn.mssm.edu\/devilab\/publications\/","title":{"rendered":"Publications"},"content":{"rendered":"

[et_pb_section fb_built=”1″ admin_label=”Fullwidth Header – Background Title Description – no slider – Section 1 ” module_class=”header-title-desciption-no-slider-section1″ _builder_version=”4.9.0″ _module_preset=”default” background_color=”rgba(0,174,239,0.09)” background_enable_color=”off” background_image=”https:\/\/labs.icahn.mssm.edu\/devilab-new\/wp-content\/uploads\/sites\/569\/2022\/07\/ai-002-1.jpg” parallax=”on” custom_padding=”||||false|false” bottom_divider_style=”ramp2″ bottom_divider_color=”#FFFFFF” bottom_divider_height=”11vw” bottom_divider_arrangement=”above_content” saved_tabs=”all” locked=”off” collapsed=”off”][et_pb_row column_structure=”1_2,1_2″ _builder_version=”4.9.0″ _module_preset=”default” background_color=”RGBA(0,0,0,0)” border_color_all=”RGBA(0,0,0,0)” collapsed=”on”][et_pb_column type=”1_2″ _builder_version=”4.9.0″ _module_preset=”default” custom_padding=”10%||8vw||false|false” custom_padding_tablet=”0vw||0vw||true|false” custom_padding_phone=”” custom_padding_last_edited=”on|tablet”][et_pb_text admin_label=”Text – Title” _builder_version=”4.9.0″ _module_preset=”b3e3ff14-5f5c-4608-8ecf-1885ce3da7aa” header_font=”||||||||” header_text_color=”#FFFFFF” header_font_size=”48px” header_line_height=”60px” custom_margin=”||10px||false|false” header_font_size_tablet=”40px” header_font_size_phone=”24px” header_font_size_last_edited=”on|desktop”]<\/p>\n

Publications<\/strong><\/h1>\n

[\/et_pb_text][et_pb_text admin_label=”Text – Description” _builder_version=”4.9.0″ _module_preset=”da86b6f0-f83c-4c7c-bdd8-3019777ddffe” text_font=”||||||||” text_text_color=”#FFFFFF” text_font_size=”20px” text_line_height=”32px” text_font_size_tablet=”15px” text_font_size_phone=”14px” text_font_size_last_edited=”on|desktop” disabled_on=”on|on|on” disabled=”on”]<\/p>\n

Our current research focuses on birth of the hair follicle niche, growth control and regeneration, and tissue regression and reorganization.<\/p>\n

[\/et_pb_text][\/et_pb_column][et_pb_column type=”1_2″ _builder_version=”4.9.0″ _module_preset=”default” background_color=”RGBA(0,0,0,0)”][\/et_pb_column][\/et_pb_row][\/et_pb_section][et_pb_section fb_built=”1″ disabled_on=”off|off|off” admin_label=”Section 28 – Blog Style Publications” module_class=”section28_blog_style_publications” _builder_version=”4.9.0″ background_color=”#FFFFFF” background_image=”https:\/\/labs.icahn.mssm.edu\/devilab-new\/wp-content\/uploads\/sites\/569\/2022\/10\/Background-1.png” parallax=”on” parallax_method=”off” custom_padding=”100px||||false|false” global_module=”2511″ saved_tabs=”all” locked=”off” collapsed=”off”][et_pb_row column_structure=”1_3,1_3,1_3″ _builder_version=”3.25″ background_size=”initial” background_position=”top_left” background_repeat=”repeat” collapsed=”on”][et_pb_column type=”1_3″ _builder_version=”3.25″ custom_padding=”|||” custom_padding__hover=”|||”][et_pb_text _builder_version=”4.9.0″ _module_preset=”default” text_font_size=”14px” text_line_height=”1.5em” background_color=”#FFFFFF” custom_padding=”20px|20px|20px|20px|true|true” link_option_url=”https:\/\/labs.icahn.mssm.edu\/rendl-lab\/wp-content\/uploads\/sites\/292\/2020\/01\/2019_Saxena.pdf” link_option_url_new_window=”on” box_shadow_style=”preset1″ box_shadow_vertical=”0px” box_shadow_blur=”40px” box_shadow_color=”rgba(0,0,0,0.14)”]<\/p>\n

Sierra S, Gomes I, Devi LA
<\/em>
Class A GPCRs: Cannabinoid and opioid receptor heteromers <\/strong><\/a>
Chapter 7. G-Protein-Coupled Receptor Dimers. 2017. doi:10.1007\/978-3-319-60174-8<\/p>\n

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Margolis EB, Fujita W, Devi LA, Fields HL
<\/em>
Two delta opioid receptor subtypes are functional in single ventral tegmental area neurons, and can interact with the mu opioid receptor.<\/a>\u00a0<\/strong>
Neuropharmacology. 2017 Jun 20. doi: 10.1016\/j.neuropharm.2017.06.019<\/p>\n

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Bobeck EN, Gomes I, Pena DA, Cummings KA, Clem RL, Mezei M, Devi LA
<\/em>
The BigLEN-GPR171 Peptide Receptor System Within the Basolateral Amygdala Regulates Anxiety-Like Behavior and Contextual Fear Conditioning.<\/a>\u00a0<\/strong>
Neuropsychopharmacology. 2017 Apr 20. doi: 10.1038\/npp.2917.79<\/p>\n

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Gomes I, Sierra S, Devi LA
<\/em>
Detection of Receptor Heteromerization Using In Situ Proximity Ligation Assay.\u00a0<\/strong><\/a>
Curr Protoc Pharmacol. 2016 Dec 13;75:2.16.1-2.16.31.<\/p>\n

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Wardman JH, Gomes I, Bobeck EN, Stockert JA, Kapoor A, Bisignano P, Gupta A, Mezei M, Kumar S, Filizola M, Devi LA
<\/em>
Identification of a small-molecule ligand that activates the neuropeptide receptor GPR171 and increases food intake.<\/a>\u00a0<\/strong>
Sci Signal. 2016 May 31;9(430):ra55.<\/p>\n

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Gupta A, Gomes I, Bobeck EN, Fakira AK, Massaro NP, Sharma I, Cav\u00e9 A, Hamm HE, Parello J, Devi LA.
<\/em>
Collybolide is a novel biased agonist of \u03ba-opioid receptors with potent antipruritic activity.\u00a0<\/strong><\/a>
Proc Natl Acad Sci U S A. 2016 May 24;113(21):6041-6. Epub 2016 May 9.<\/p>\n

[\/et_pb_text][\/et_pb_column][\/et_pb_row][et_pb_row column_structure=”1_4,1_4,1_4,1_4″ _builder_version=”3.25″ background_size=”initial” background_position=”top_left” background_repeat=”repeat” collapsed=”on”][et_pb_column type=”1_4″ _builder_version=”3.25″ custom_padding=”|||” custom_padding__hover=”|||”][et_pb_text _builder_version=”4.9.0″ _module_preset=”default” text_font_size=”14px” text_line_height=”1.5em” background_color=”#FFFFFF” custom_padding=”20px|20px|20px|20px|true|true” link_option_url=”https:\/\/labs.icahn.mssm.edu\/rendl-lab\/wp-content\/uploads\/sites\/292\/2020\/01\/2019_Saxena.pdf” link_option_url_new_window=”on” box_shadow_style=”preset1″ box_shadow_vertical=”0px” box_shadow_blur=”40px” box_shadow_color=”rgba(0,0,0,0.14)”]<\/p>\n

Gomes I, Bobeck EN, Margolis EB, Gupta A, Sierra S, Fakira AK, Fujita W, M\u00fcller TD, M\u00fcller A, Tsch\u00f6p MH, Kleinau G, Fricker LD, Devi LA.
<\/em>
Identification of GPR83 as the receptor for the neuroendocrine peptide PEN.\u00a0<\/strong><\/a>
Sci Signal. 2016 Apr 26;9(425):ra43.<\/p>\n

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Gomes I, Ayoub MA, Fujita W, Jaeger WC, Pfleger KD, Devi LA.
<\/em>
G Protein-Coupled Receptor Heteromers.\u00a0<\/strong><\/a>
Annu Rev Pharmacol Toxicol. 2016;56:403-25.Epub 2015 Oct 22.<\/p>\n

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Stockton SD Jr, Gomes I, Liu T, Moraje C, Hip\u00f3lito L, Jones MR, Ma\u2019ayan A, Mor\u00f3n JA, Li H, Devi LA.
<\/em>
Morphine Regulated Synaptic Networks Revealed by Integrated Proteomics and Network Analysis.\u00a0<\/strong><\/a>
Molecular & Cellular Proteomics. 2015 Jul 6. [Epub ahead of print]<\/p>\n

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Stockert JA, Devi LA.
<\/em>
Advancements in therapeutically targeting orphan GPCRs.\u00a0<\/strong><\/a>
Frontiers in Pharmacology. 2015 May 8;6:100<\/p>\n

[\/et_pb_text][\/et_pb_column][\/et_pb_row][et_pb_row column_structure=”1_5,1_5,1_5,1_5,1_5″ _builder_version=”3.25″ background_size=”initial” background_position=”top_left” background_repeat=”repeat” collapsed=”on”][et_pb_column type=”1_5″ _builder_version=”3.25″ custom_padding=”|||” custom_padding__hover=”|||”][et_pb_text _builder_version=”4.9.0″ _module_preset=”default” text_font_size=”14px” text_line_height=”1.5em” background_color=”#FFFFFF” custom_padding=”20px|20px|20px|20px|true|true” link_option_url=”https:\/\/labs.icahn.mssm.edu\/rendl-lab\/wp-content\/uploads\/sites\/292\/2020\/01\/2019_Saxena.pdf” link_option_url_new_window=”on” box_shadow_style=”preset1″ box_shadow_vertical=”0px” box_shadow_blur=”40px” box_shadow_color=”rgba(0,0,0,0.14)”]<\/p>\n

Gupta A, Fujita W, Gomes I, Bobeck E, Devi LA.
<\/em>
Endothelin-converting enzyme 2 differentially regulates opioid receptor activity.\u00a0<\/strong><\/a>
British Journal of Pharmacology. 2015 Jan;172(2):704-19. Epub 2014 Sep 5.<\/p>\n

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Cox, B. M., Christie, M. J., Devi, LA. Toll, L. and Traynor, J.R.
<\/em>
Challenges for opioid receptor nomenclature.\u00a0<\/strong><\/a>
British Journal of Pharmacology. 2015 Jan;172(2):317-23. Epub 2014 Jul 1.<\/p>\n

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Fujita W, Gomes I, Devi LA.
<\/em>
Heteromers of \u03bc-\u03b4 opioid receptors: new pharmacology and novel therapeutic possibilities.\u00a0<\/strong><\/a>
British Journal of Pharmacology. 2015 Jan;172(2):375-87. Epub 2014 Jul 1.<\/p>\n

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Gomes I, Gupta A, Bushlin I, Devi LA.
<\/em>
Antibodies to probe endogenous G protein-coupled receptor heteromer expression, regulation, and function.<\/a>\u00a0<\/strong>
Frontiers in Pharmacology. 2014 Dec 3;5:268.<\/p>\n

[\/et_pb_text][\/et_pb_column][et_pb_column type=”1_5″ _builder_version=”4.9.0″ _module_preset=”default”][et_pb_text admin_label=”Text” _builder_version=”4.9.0″ _module_preset=”default” text_font_size=”14px” text_line_height=”1.5em” background_color=”#FFFFFF” custom_padding=”20px|20px|20px|20px|true|true” link_option_url=”https:\/\/labs.icahn.mssm.edu\/rendl-lab\/wp-content\/uploads\/sites\/292\/2020\/01\/2019_Saxena.pdf” link_option_url_new_window=”on” box_shadow_style=”preset1″ box_shadow_vertical=”0px” box_shadow_blur=”40px” box_shadow_color=”rgba(0,0,0,0.14)”]<\/p>\n

Fujita W, Gomes I, Dove LS, Prohaska D, McIntyre G, Devi LA.
<\/em>
Molecular characterization of eluxadoline as a potential ligand targeting mu-delta opioid receptor heteromers.<\/a>\u00a0<\/strong>
Biochemical Pharmacology. 2014 Dec 1;92(3):448-56.<\/p>\n

[\/et_pb_text][\/et_pb_column][\/et_pb_row][et_pb_row column_structure=”1_5,1_5,1_5,1_5,1_5″ _builder_version=”3.25″ background_size=”initial” background_position=”top_left” background_repeat=”repeat” collapsed=”on”][et_pb_column type=”1_5″ _builder_version=”3.25″ custom_padding=”|||” custom_padding__hover=”|||”][et_pb_text _builder_version=”4.9.0″ _module_preset=”default” text_font_size=”14px” text_line_height=”1.5em” background_color=”#FFFFFF” custom_padding=”20px|20px|20px|20px|true|true” link_option_url=”https:\/\/labs.icahn.mssm.edu\/rendl-lab\/wp-content\/uploads\/sites\/292\/2020\/01\/2019_Saxena.pdf” link_option_url_new_window=”on” box_shadow_style=”preset1″ box_shadow_vertical=”0px” box_shadow_blur=”40px” box_shadow_color=”rgba(0,0,0,0.14)”]<\/p>\n

Kivell B, Uzelac Z, Sundaramurthy S, Rajamanickam J, Ewald A, Chefer V, Jaligam V, Bolan E, Simonson B, Annamalai B, Mannangatti P, Prisinzano TE, Gomes I, Devi LA, Jayanthi LD, Sitte HH, Ramamoorthy S, Shippenberg TS. Salvinorin
<\/em>
Salvinorin A regulates dopamine transporter function via a kappa opioid receptor and ERK1\/2-dependent mechanism.<\/a>\u00a0<\/strong>
Neuropharmacology. 2014 Nov;86:228-40.<\/p>\n

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Fujita W, Gomes I, Devi LA.
<\/em>
Revolution in GPCR signalling: opioid receptor heteromers as novel therapeutic targets: IUPHAR review 10.<\/a>\u00a0<\/strong>
British Journal of Pharmacology. 2014 Sep;171(18):4155-76.<\/p>\n

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Gupta A, Gomes I, Wardman J, Devi LA.
<\/em>
Opioid Receptor Function is Regulated by Post-endocytic Peptide Processing.\u00a0<\/strong><\/a>
Journal of Biological Chemistry 2014 Jul 11;289(28):19613-26.<\/p>\n

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Toniolo EF, Maique ET, Ferreira WA Jr, Heimann AS, Ferro ES, Ramos-Ortolaza DL, Miller L, Devi LA, Dale CS.
<\/em>
Hemopressin, an inverse agonist of cannabinoid receptors, inhibits neuropathic pain in rats.\u00a0<\/strong><\/a>
Peptides. 2014 Jun;56:125-31.<\/p>\n

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Guerrero M, Urbano M, Brown SJ, Cayanan C, Ferguson J, Cameron M, Devi LA, Roberts E, Rosen H.
<\/em>
Optimization and characterization of an opioid kappa receptor (OPRK1) antagonist.\u00a0<\/strong><\/a>
Probe Reports from the NIH Molecular Libraries Program [Internet]. Bethesda (MD): National Center for Biotechnology Information (US); 2010-.2013 Apr 15 [updated 2014 Sep 18].<\/p>\n

[\/et_pb_text][\/et_pb_column][\/et_pb_row][et_pb_row column_structure=”1_5,1_5,1_5,1_5,1_5″ _builder_version=”3.25″ background_size=”initial” background_position=”top_left” background_repeat=”repeat” collapsed=”on”][et_pb_column type=”1_5″ _builder_version=”3.25″ custom_padding=”|||” custom_padding__hover=”|||”][et_pb_text _builder_version=”4.9.0″ _module_preset=”default” text_font_size=”14px” text_line_height=”1.5em” background_color=”#FFFFFF” custom_padding=”20px|20px|20px|20px|true|true” link_option_url=”https:\/\/labs.icahn.mssm.edu\/rendl-lab\/wp-content\/uploads\/sites\/292\/2020\/01\/2019_Saxena.pdf” link_option_url_new_window=”on” box_shadow_style=”preset1″ box_shadow_vertical=”0px” box_shadow_blur=”40px” box_shadow_color=”rgba(0,0,0,0.14)”]<\/p>\n

Yang, L, Rozenfeld, R, Wu, D, Devi, LA, Zhang, Z and Cederbaum, A.
<\/em>
Cannabidiol protects liver from binge alcohol-induced steatosis by mechanisms including inhibition of oxidative stress and increase in autophagy.<\/a>\u00a0<\/strong>
Free. Radical Biology & Medicine. 68:260-267, 2014 Mar; Epub 2014 Jan 4.<\/p>\n

[\/et_pb_text][\/et_pb_column][et_pb_column type=”1_5″ _builder_version=”3.25″ custom_padding=”|||” custom_padding__hover=”|||”][et_pb_text _builder_version=”4.9.0″ _module_preset=”default” text_font_size=”14px” text_line_height=”1.5em” background_color=”#FFFFFF” custom_padding=”20px|20px|20px|20px|true|true” link_option_url=”https:\/\/labs.icahn.mssm.edu\/rendl-lab\/wp-content\/uploads\/sites\/292\/2020\/01\/2019_Saxena.pdf” link_option_url_new_window=”on” box_shadow_style=”preset1″ box_shadow_vertical=”0px” box_shadow_blur=”40px” box_shadow_color=”rgba(0,0,0,0.14)”]<\/p>\n

Matsumoto, K, Narita, M, Muramatsu, N, Nakayama, T, Misawa, K, Kitajima, M, Tashima, K, Devi, LA, Suzuki, T, Takayama, H and Horie, S.
<\/em>
The orally active opioid m\/d dual agonist MGM-16, a derivative of indole alkaloid mitragynine, exhibits potent anti-allodynic effect on neuropathic pain in mice.<\/a>\u00a0<\/strong>
Journal of Pharmacology and Experimental Therapeutics. 348:383-92, 2014 March<\/p>\n

[\/et_pb_text][\/et_pb_column][et_pb_column type=”1_5″ _builder_version=”4.9.0″ _module_preset=”default”][et_pb_text _builder_version=”4.9.0″ _module_preset=”default” text_font_size=”14px” text_line_height=”1.5em” background_color=”#FFFFFF” custom_padding=”20px|20px|20px|20px|true|true” link_option_url=”https:\/\/labs.icahn.mssm.edu\/rendl-lab\/wp-content\/uploads\/sites\/292\/2020\/01\/2019_Saxena.pdf” link_option_url_new_window=”on” box_shadow_style=”preset1″ box_shadow_vertical=”0px” box_shadow_blur=”40px” box_shadow_color=”rgba(0,0,0,0.14)”]<\/p>\n

Ferr\u00e9 S, Casad\u00f3 V, Devi LA, Filizola M, Jockers R, Lohse MJ, Milligan G, Pin JP, Guitart X.
<\/em>
G protein-coupled receptor oligomerization revisited: functional and pharmacological perspectives.\u00a0<\/strong><\/a>
Pharmacological Reviews. 2014 Feb 10;66(2):413-34.<\/p>\n

[\/et_pb_text][\/et_pb_column][et_pb_column type=”1_5″ _builder_version=”4.9.0″ _module_preset=”default”][et_pb_text _builder_version=”4.9.0″ _module_preset=”default” text_font_size=”14px” text_line_height=”1.5em” background_color=”#FFFFFF” custom_padding=”20px|20px|20px|20px|true|true” link_option_url=”https:\/\/labs.icahn.mssm.edu\/rendl-lab\/wp-content\/uploads\/sites\/292\/2020\/01\/2019_Saxena.pdf” link_option_url_new_window=”on” box_shadow_style=”preset1″ box_shadow_vertical=”0px” box_shadow_blur=”40px” box_shadow_color=”rgba(0,0,0,0.14)”]<\/p>\n

Stockton SD Jr, Devi LA.
<\/em>
An integrated quantitative proteomics and systems biology approach to explore synaptic protein profile changes during morphine exposure.\u00a0<\/strong><\/a>
Neuropsychopharmacology 2014 Jan; 39(1).<\/p>\n

[\/et_pb_text][\/et_pb_column][et_pb_column type=”1_5″ _builder_version=”4.9.0″ _module_preset=”default”][et_pb_text admin_label=”Text” _builder_version=”4.9.0″ _module_preset=”default” text_font_size=”14px” text_line_height=”1.5em” background_color=”#FFFFFF” custom_padding=”20px|20px|20px|20px|true|true” link_option_url=”https:\/\/labs.icahn.mssm.edu\/rendl-lab\/wp-content\/uploads\/sites\/292\/2020\/01\/2019_Saxena.pdf” link_option_url_new_window=”on” box_shadow_style=”preset1″ box_shadow_vertical=”0px” box_shadow_blur=”40px” box_shadow_color=”rgba(0,0,0,0.14)”]<\/p>\n

Gomes I, Aryal DK, Wardman JH, Gupta A, Gagnidze K, Rodriguiz RM, Kumar S, Wetsel WC, Pintar JE, Fricker LD, Devi LA.
<\/em>
GPR171 is a hypothalamic G protein-coupled receptor for BigLEN, a neuropeptide involved in feeding.<\/a>\u00a0<\/strong>
Proceedings of the National Academy of Sciences U S A. 2013 Oct 1;110(40):16211-16216.<\/p>\n

[\/et_pb_text][\/et_pb_column][\/et_pb_row][et_pb_row column_structure=”1_5,1_5,1_5,1_5,1_5″ _builder_version=”3.25″ background_size=”initial” background_position=”top_left” background_repeat=”repeat” collapsed=”on”][et_pb_column type=”1_5″ _builder_version=”3.25″ custom_padding=”|||” custom_padding__hover=”|||”][et_pb_text _builder_version=”4.9.0″ _module_preset=”default” text_font_size=”14px” text_line_height=”1.5em” background_color=”#FFFFFF” custom_padding=”20px|20px|20px|20px|true|true” link_option_url=”https:\/\/labs.icahn.mssm.edu\/rendl-lab\/wp-content\/uploads\/sites\/292\/2020\/01\/2019_Saxena.pdf” link_option_url_new_window=”on” box_shadow_style=”preset1″ box_shadow_vertical=”0px” box_shadow_blur=”40px” box_shadow_color=”rgba(0,0,0,0.14)”]<\/p>\n

Gomes I, Fujita W, Gupta A, Saldanha AS, Negri A, Pinello CE, Roberts E, Filizola M, Hodder P, Devi LA.
<\/em>
Identification of a \u03bc-\u03b4 opioid receptor heteromer-biased agonist with antinociceptive activity.\u00a0<\/strong><\/a>
Proceedings of the National Academy of Sciences U S A. 2013 Jul 16;110(29):12072-7.<\/p>\n

[\/et_pb_text][\/et_pb_column][et_pb_column type=”1_5″ _builder_version=”3.25″ custom_padding=”|||” custom_padding__hover=”|||”][et_pb_text _builder_version=”4.9.0″ _module_preset=”default” text_font_size=”14px” text_line_height=”1.5em” background_color=”#FFFFFF” custom_padding=”20px|20px|20px|20px|true|true” link_option_url=”https:\/\/labs.icahn.mssm.edu\/rendl-lab\/wp-content\/uploads\/sites\/292\/2020\/01\/2019_Saxena.pdf” link_option_url_new_window=”on” box_shadow_style=”preset1″ box_shadow_vertical=”0px” box_shadow_blur=”40px” box_shadow_color=”rgba(0,0,0,0.14)”]<\/p>\n

Narita M, Imai S, Nakamura A, Ozeki A, Asato M, Rahmadi M, Sudo Y, Hojo M, Uezono Y, Devi LA, Kuzumaki N, Suzuki T.
<\/em>
Possible involvement of prolonging spinal \u00b5-opioid receptor desensitization in the development of antihyperalgesic tolerance to \u00b5-opioids under a neuropathic pain-like state.\u00a0<\/strong><\/a>
Addict Biol. 2013 Jul;18(4):614-22.<\/p>\n

[\/et_pb_text][\/et_pb_column][et_pb_column type=”1_5″ _builder_version=”4.9.0″ _module_preset=”default”][et_pb_text _builder_version=”4.9.0″ _module_preset=”default” text_font_size=”14px” text_line_height=”1.5em” background_color=”#FFFFFF” custom_padding=”20px|20px|20px|20px|true|true” link_option_url=”https:\/\/labs.icahn.mssm.edu\/rendl-lab\/wp-content\/uploads\/sites\/292\/2020\/01\/2019_Saxena.pdf” link_option_url_new_window=”on” box_shadow_style=”preset1″ box_shadow_vertical=”0px” box_shadow_blur=”40px” box_shadow_color=”rgba(0,0,0,0.14)”]<\/p>\n

Hern\u00e1ndez-Gea V, Hilscher M, Rozenfeld R, Lim MP, Nieto N, Werner S, Devi LA, Friedman SL.
<\/em>
Endoplasmic reticulum stress induces fibrogenic activity in hepatic stellate cells through autophagy.\u00a0<\/strong><\/a>
J Hepatol. 2013 Jul;59(1):98-104.<\/p>\n

[\/et_pb_text][\/et_pb_column][et_pb_column type=”1_5″ _builder_version=”4.9.0″ _module_preset=”default”][et_pb_text _builder_version=”4.9.0″ _module_preset=”default” text_font_size=”14px” text_line_height=”1.5em” background_color=”#FFFFFF” custom_padding=”20px|20px|20px|20px|true|true” link_option_url=”https:\/\/labs.icahn.mssm.edu\/rendl-lab\/wp-content\/uploads\/sites\/292\/2020\/01\/2019_Saxena.pdf” link_option_url_new_window=”on” box_shadow_style=”preset1″ box_shadow_vertical=”0px” box_shadow_blur=”40px” box_shadow_color=”rgba(0,0,0,0.14)”]<\/p>\n

Gomes I, Fujita W, Chandrakala MV, Devi LA.
<\/em>
Disease-specific heteromerization of G-protein-coupled receptors that target drugs of abuse.\u00a0<\/strong><\/a>
Progress in Molecular Biology and Translational Science. 2013;117:207-65.<\/p>\n

[\/et_pb_text][\/et_pb_column][et_pb_column type=”1_5″ _builder_version=”4.9.0″ _module_preset=”default”][et_pb_text admin_label=”Text” _builder_version=”4.9.0″ _module_preset=”default” text_font_size=”14px” text_line_height=”1.5em” background_color=”#FFFFFF” custom_padding=”20px|20px|20px|20px|true|true” link_option_url=”https:\/\/labs.icahn.mssm.edu\/rendl-lab\/wp-content\/uploads\/sites\/292\/2020\/01\/2019_Saxena.pdf” link_option_url_new_window=”on” box_shadow_style=”preset1″ box_shadow_vertical=”0px” box_shadow_blur=”40px” box_shadow_color=”rgba(0,0,0,0.14)”]<\/p>\n

Gomes I, Gupta A, Devi LA.
<\/em>
G-protein-coupled heteromers: regulation in disease.\u00a0<\/strong><\/a>
Methods in Enzymology. 2013;521:219-38.<\/p>\n

[\/et_pb_text][\/et_pb_column][\/et_pb_row][et_pb_row column_structure=”1_5,1_5,1_5,1_5,1_5″ _builder_version=”3.25″ background_size=”initial” background_position=”top_left” background_repeat=”repeat” collapsed=”on”][et_pb_column type=”1_5″ _builder_version=”3.25″ custom_padding=”|||” custom_padding__hover=”|||”][et_pb_text _builder_version=”4.9.0″ _module_preset=”default” text_font_size=”14px” text_line_height=”1.5em” background_color=”#FFFFFF” custom_padding=”20px|20px|20px|20px|true|true” link_option_url=”https:\/\/labs.icahn.mssm.edu\/rendl-lab\/wp-content\/uploads\/sites\/292\/2020\/01\/2019_Saxena.pdf” link_option_url_new_window=”on” box_shadow_style=”preset1″ box_shadow_vertical=”0px” box_shadow_blur=”40px” box_shadow_color=”rgba(0,0,0,0.14)”]<\/p>\n

Filizola M, Devi LA.
<\/em>
Grand opening of structure-guided design for novel opioids.\u00a0<\/strong><\/a>
Trends in Pharmacological Sciences. 2013 Jan;34(1):6-12. Epub 2012 Nov 3. Review.<\/p>\n

[\/et_pb_text][\/et_pb_column][et_pb_column type=”1_5″ _builder_version=”3.25″ custom_padding=”|||” custom_padding__hover=”|||”][et_pb_text _builder_version=”4.9.0″ _module_preset=”default” text_font_size=”14px” text_line_height=”1.5em” background_color=”#FFFFFF” custom_padding=”20px|20px|20px|20px|true|true” link_option_url=”https:\/\/labs.icahn.mssm.edu\/rendl-lab\/wp-content\/uploads\/sites\/292\/2020\/01\/2019_Saxena.pdf” link_option_url_new_window=”on” box_shadow_style=”preset1″ box_shadow_vertical=”0px” box_shadow_blur=”40px” box_shadow_color=”rgba(0,0,0,0.14)”]<\/p>\n

Pinello C, Guerrero M, Eberhart C, Volmar CH, Saldanha SA, Cayanan C, Urbano M, Brown SJ, Ferguson J, Gomes I, Devi LA, Roberts E, Hodder P, Rosen H.
<\/em>
Characterization of an agonist probe for opioid receptor mu 1 (OPRM1)-opioid receptor delta 1 (OPRD1) heterodimerization.\u00a0<\/strong><\/a>
Probe Reports from the NIH Molecular Libraries Program [Internet]. Bethesda (MD): National Center for Biotechnology Information (US); 2010-2012 Dec 17 [updated 2013 Apr 5].<\/p>\n

[\/et_pb_text][\/et_pb_column][et_pb_column type=”1_5″ _builder_version=”4.9.0″ _module_preset=”default”][et_pb_text _builder_version=”4.9.0″ _module_preset=”default” text_font_size=”14px” text_line_height=”1.5em” background_color=”#FFFFFF” custom_padding=”20px|20px|20px|20px|true|true” link_option_url=”https:\/\/labs.icahn.mssm.edu\/rendl-lab\/wp-content\/uploads\/sites\/292\/2020\/01\/2019_Saxena.pdf” link_option_url_new_window=”on” box_shadow_style=”preset1″ box_shadow_vertical=”0px” box_shadow_blur=”40px” box_shadow_color=”rgba(0,0,0,0.14)”]<\/p>\n

Bushlin I, Gupta A, Stockton SD Jr, Miller LK, Devi LA.
<\/em>
Dimerization with cannabinoid receptors allosterically modulates delta opioid receptor activity during neuropathic pain.\u00a0<\/strong><\/a>
PLoS One. 2012;7(12):e49789. Epub 2012 Dec 14.<\/p>\n

[\/et_pb_text][\/et_pb_column][et_pb_column type=”1_5″ _builder_version=”4.9.0″ _module_preset=”default”][et_pb_text _builder_version=”4.9.0″ _module_preset=”default” text_font_size=”14px” text_line_height=”1.5em” background_color=”#FFFFFF” custom_padding=”20px|20px|20px|20px|true|true” link_option_url=”https:\/\/labs.icahn.mssm.edu\/rendl-lab\/wp-content\/uploads\/sites\/292\/2020\/01\/2019_Saxena.pdf” link_option_url_new_window=”on” box_shadow_style=”preset1″ box_shadow_vertical=”0px” box_shadow_blur=”40px” box_shadow_color=”rgba(0,0,0,0.14)”]<\/p>\n

Filizola M, Devi LA.
<\/em>
Structural biology: How opioid drugs bind to receptors.\u00a0<\/strong><\/a>
Nature. 2012 May 16;485(7398):314-7.<\/p>\n

[\/et_pb_text][\/et_pb_column][et_pb_column type=”1_5″ _builder_version=”4.9.0″ _module_preset=”default”][et_pb_text admin_label=”Text” _builder_version=”4.9.0″ _module_preset=”default” text_font_size=”14px” text_line_height=”1.5em” background_color=”#FFFFFF” custom_padding=”20px|20px|20px|20px|true|true” link_option_url=”https:\/\/labs.icahn.mssm.edu\/rendl-lab\/wp-content\/uploads\/sites\/292\/2020\/01\/2019_Saxena.pdf” link_option_url_new_window=”on” box_shadow_style=”preset1″ box_shadow_vertical=”0px” box_shadow_blur=”40px” box_shadow_color=”rgba(0,0,0,0.14)”]<\/p>\n

Costantino CM, Gomes I, Stockton SD, Lim MP, Devi LA.
<\/em>
Opioid receptor heteromers in analgesia.\u00a0<\/strong><\/a>
Expert Reviews in Molecular Medicine. 2012 Apr 10;14:e9.<\/p>\n

[\/et_pb_text][\/et_pb_column][\/et_pb_row][et_pb_row column_structure=”1_5,1_5,1_5,1_5,1_5″ _builder_version=”3.25″ background_size=”initial” background_position=”top_left” background_repeat=”repeat” collapsed=”on”][et_pb_column type=”1_5″ _builder_version=”3.25″ custom_padding=”|||” custom_padding__hover=”|||”][et_pb_text _builder_version=”4.9.0″ _module_preset=”default” text_font_size=”14px” text_line_height=”1.5em” background_color=”#FFFFFF” custom_padding=”20px|20px|20px|20px|true|true” link_option_url=”https:\/\/labs.icahn.mssm.edu\/rendl-lab\/wp-content\/uploads\/sites\/292\/2020\/01\/2019_Saxena.pdf” link_option_url_new_window=”on” box_shadow_style=”preset1″ box_shadow_vertical=”0px” box_shadow_blur=”40px” box_shadow_color=”rgba(0,0,0,0.14)”]<\/p>\n

Costantino CM, Gupta A, Yewdall AW, Dale BM, Devi LA, Chen BK.
<\/em>
Cannabinoid receptor 2-mediated attenuation of CXCR4-tropic HIV infection in primary CD4+ T cells.\u00a0<\/strong><\/a>
PLoS One. 2012;7(3):e33961. Epub 2012 Mar 20.<\/p>\n

[\/et_pb_text][\/et_pb_column][et_pb_column type=”1_5″ _builder_version=”3.25″ custom_padding=”|||” custom_padding__hover=”|||”][et_pb_text _builder_version=”4.9.0″ _module_preset=”default” text_font_size=”14px” text_line_height=”1.5em” background_color=”#FFFFFF” custom_padding=”20px|20px|20px|20px|true|true” link_option_url=”https:\/\/labs.icahn.mssm.edu\/rendl-lab\/wp-content\/uploads\/sites\/292\/2020\/01\/2019_Saxena.pdf” link_option_url_new_window=”on” box_shadow_style=”preset1″ box_shadow_vertical=”0px” box_shadow_blur=”40px” box_shadow_color=”rgba(0,0,0,0.14)”]<\/p>\n

Rozenfeld R, Bushlin I, Gomes I, Tzavaras N, Gupta A, Neves S, Battini L, Gusella GL, Lachmann A, Ma\u2019ayan A, Blitzer RD, Devi LA.
<\/em>
Receptor heteromerization expands the repertoire of cannabinoid signaling in rodent neurons.\u00a0<\/strong><\/a>
PLoS One. 2012;7(1):e29239. Epub 2012 Jan 3.<\/p>\n

[\/et_pb_text][\/et_pb_column][et_pb_column type=”1_5″ _builder_version=”4.9.0″ _module_preset=”default”][et_pb_text _builder_version=”4.9.0″ _module_preset=”default” text_font_size=”14px” text_line_height=”1.5em” background_color=”#FFFFFF” custom_padding=”20px|20px|20px|20px|true|true” link_option_url=”https:\/\/labs.icahn.mssm.edu\/rendl-lab\/wp-content\/uploads\/sites\/292\/2020\/01\/2019_Saxena.pdf” link_option_url_new_window=”on” box_shadow_style=”preset1″ box_shadow_vertical=”0px” box_shadow_blur=”40px” box_shadow_color=”rgba(0,0,0,0.14)”]<\/p>\n

Stockton SD Jr, Devi LA.
<\/em>
Functional relevance of \u03bc-\u03b4 opioid receptor heteromerization: a role in novel signaling and implications for the treatment of addiction disorders: from a symposium on new concepts in mu-opioid pharmacology.\u00a0<\/strong><\/a>
Drug and Alcohol Dependence. 2012 Mar 1;121(3):167-72. Epub 2011 Nov 23. Review.<\/p>\n

[\/et_pb_text][\/et_pb_column][et_pb_column type=”1_5″ _builder_version=”4.9.0″ _module_preset=”default”][et_pb_text _builder_version=”4.9.0″ _module_preset=”default” text_font_size=”14px” text_line_height=”1.5em” background_color=”#FFFFFF” custom_padding=”20px|20px|20px|20px|true|true” link_option_url=”https:\/\/labs.icahn.mssm.edu\/rendl-lab\/wp-content\/uploads\/sites\/292\/2020\/01\/2019_Saxena.pdf” link_option_url_new_window=”on” box_shadow_style=”preset1″ box_shadow_vertical=”0px” box_shadow_blur=”40px” box_shadow_color=”rgba(0,0,0,0.14)”]<\/p>\n

Berg KA, Rowan MP, Gupta A, Sanchez TA, Silva M, Gomes I, McGuire BA, Portoghese PS, Hargreaves KM, Devi LA, Clarke WP.
<\/em>
Allosteric interactions between \u03b4 and \u03ba opioid receptors in peripheral sensory neurons.\u00a0<\/strong><\/a>
Molecular Pharmacology. 2012 Feb;81(2):264-72. Epub 2011 Nov 9.<\/p>\n

[\/et_pb_text][\/et_pb_column][et_pb_column type=”1_5″ _builder_version=”4.9.0″ _module_preset=”default”][et_pb_text admin_label=”Text” _builder_version=”4.9.0″ _module_preset=”default” text_font_size=”14px” text_line_height=”1.5em” background_color=”#FFFFFF” custom_padding=”20px|20px|20px|20px|true|true” link_option_url=”https:\/\/labs.icahn.mssm.edu\/rendl-lab\/wp-content\/uploads\/sites\/292\/2020\/01\/2019_Saxena.pdf” link_option_url_new_window=”on” box_shadow_style=”preset1″ box_shadow_vertical=”0px” box_shadow_blur=”40px” box_shadow_color=”rgba(0,0,0,0.14)”]<\/p>\n

Miller LK, Hou X, Rodriguiz RM, Gagnidze K, Sweedler JV, Wetsel WC, Devi LA.
<\/em>
Mice deficient in endothelin-converting enzyme-2 exhibit abnormal responses to morphine and altered peptide levels in the spinal cord.\u00a0<\/strong><\/a>
Journal of Neurochemistry. 2011 Dec;119(5):1074-85. Epub 2011 Nov 1.<\/p>\n

[\/et_pb_text][\/et_pb_column][\/et_pb_row][et_pb_row column_structure=”1_5,1_5,1_5,1_5,1_5″ _builder_version=”3.25″ background_size=”initial” background_position=”top_left” background_repeat=”repeat” collapsed=”on”][et_pb_column type=”1_5″ _builder_version=”3.25″ custom_padding=”|||” custom_padding__hover=”|||”][et_pb_text _builder_version=”4.9.0″ _module_preset=”default” text_font_size=”14px” text_line_height=”1.5em” background_color=”#FFFFFF” custom_padding=”20px|20px|20px|20px|true|true” link_option_url=”https:\/\/labs.icahn.mssm.edu\/rendl-lab\/wp-content\/uploads\/sites\/292\/2020\/01\/2019_Saxena.pdf” link_option_url_new_window=”on” box_shadow_style=”preset1″ box_shadow_vertical=”0px” box_shadow_blur=”40px” box_shadow_color=”rgba(0,0,0,0.14)”]<\/p>\n

Abul-Husn NS, Annangudi SP, Ma\u2019ayan A, Ramos-Ortolaza DL, Stockton SD Jr, Gomes I, Sweedler JV, Devi LA.
<\/em>
Chronic morphine alters the presynaptic protein profile: identification of novel molecular targets using proteomics and network analysis.\u00a0<\/strong><\/a>
PLoS One. 2011;6(10):e25535. Epub 2011 Oct 17.<\/p>\n

[\/et_pb_text][\/et_pb_column][et_pb_column type=”1_5″ _builder_version=”3.25″ custom_padding=”|||” custom_padding__hover=”|||”][et_pb_text _builder_version=”4.9.0″ _module_preset=”default” text_font_size=”14px” text_line_height=”1.5em” background_color=”#FFFFFF” custom_padding=”20px|20px|20px|20px|true|true” link_option_url=”https:\/\/labs.icahn.mssm.edu\/rendl-lab\/wp-content\/uploads\/sites\/292\/2020\/01\/2019_Saxena.pdf” link_option_url_new_window=”on” box_shadow_style=”preset1″ box_shadow_vertical=”0px” box_shadow_blur=”40px” box_shadow_color=”rgba(0,0,0,0.14)”]<\/p>\n

Gupta A, Devi LA, Gomes I.
<\/em>
Potentiation of \u03bc-opioid receptor-mediated signaling by ketamine.\u00a0<\/strong><\/a>
Journal of Neurochemistry. 2011 Oct;119(2):294-302. Epub 2011 Sep 20.<\/p>\n

[\/et_pb_text][\/et_pb_column][et_pb_column type=”1_5″ _builder_version=”4.9.0″ _module_preset=”default”][et_pb_text _builder_version=”4.9.0″ _module_preset=”default” text_font_size=”14px” text_line_height=”1.5em” background_color=”#FFFFFF” custom_padding=”20px|20px|20px|20px|true|true” link_option_url=”https:\/\/labs.icahn.mssm.edu\/rendl-lab\/wp-content\/uploads\/sites\/292\/2020\/01\/2019_Saxena.pdf” link_option_url_new_window=”on” box_shadow_style=”preset1″ box_shadow_vertical=”0px” box_shadow_blur=”40px” box_shadow_color=”rgba(0,0,0,0.14)”]<\/p>\n

Miller LK, Devi LA.
<\/em>
The highs and lows of cannabinoid receptor expression in disease: mechanisms and their therapeutic implications.\u00a0<\/strong><\/a>
Pharmacological Reviews. 2011 Sep;63(3):461-70. Epub 2011 Jul 13. Review.<\/p>\n

[\/et_pb_text][\/et_pb_column][et_pb_column type=”1_5″ _builder_version=”4.9.0″ _module_preset=”default”][et_pb_text _builder_version=”4.9.0″ _module_preset=”default” text_font_size=”14px” text_line_height=”1.5em” background_color=”#FFFFFF” custom_padding=”20px|20px|20px|20px|true|true” link_option_url=”https:\/\/labs.icahn.mssm.edu\/rendl-lab\/wp-content\/uploads\/sites\/292\/2020\/01\/2019_Saxena.pdf” link_option_url_new_window=”on” box_shadow_style=”preset1″ box_shadow_vertical=”0px” box_shadow_blur=”40px” box_shadow_color=”rgba(0,0,0,0.14)”]<\/p>\n

Imai S, Sudo Y, Nakamura A, Ozeki A, Asato M, Hojo M, Devi LA, Kuzumaki N, Suzuki T, Uezono Y, Narita M.
<\/em>
Possible involvement of \u03b2-endorphin in a loss of the coordinated balance of \u03bc-opioid receptors trafficking processes by fentanyl.\u00a0<\/strong><\/a>
Synapse. 2011 Sep;65(9):962-6. Epub 2011 Apr 11. No abstract available.<\/p>\n

[\/et_pb_text][\/et_pb_column][et_pb_column type=”1_5″ _builder_version=”4.9.0″ _module_preset=”default”][et_pb_text admin_label=”Text” _builder_version=”4.9.0″ _module_preset=”default” text_font_size=”14px” text_line_height=”1.5em” background_color=”#FFFFFF” custom_padding=”20px|20px|20px|20px|true|true” link_option_url=”https:\/\/labs.icahn.mssm.edu\/rendl-lab\/wp-content\/uploads\/sites\/292\/2020\/01\/2019_Saxena.pdf” link_option_url_new_window=”on” box_shadow_style=”preset1″ box_shadow_vertical=”0px” box_shadow_blur=”40px” box_shadow_color=”rgba(0,0,0,0.14)”]<\/p>\n

Lim MP, Devi LA, Rozenfeld R.
<\/em>
Cannabidiol causes activated hepatic stellate cell death through a mechanism of endoplasmic reticulum stress-induced apoptosis.\u00a0<\/strong><\/a>
Cell Death & Disease. 2011 Jun 9;2:e170.<\/p>\n

[\/et_pb_text][\/et_pb_column][\/et_pb_row][et_pb_row column_structure=”1_5,1_5,1_5,1_5,1_5″ _builder_version=”3.25″ background_size=”initial” background_position=”top_left” background_repeat=”repeat” collapsed=”on”][et_pb_column type=”1_5″ _builder_version=”3.25″ custom_padding=”|||” custom_padding__hover=”|||”][et_pb_text _builder_version=”4.9.0″ _module_preset=”default” text_font_size=”14px” text_line_height=”1.5em” background_color=”#FFFFFF” custom_padding=”20px|20px|20px|20px|true|true” link_option_url=”https:\/\/labs.icahn.mssm.edu\/rendl-lab\/wp-content\/uploads\/sites\/292\/2020\/01\/2019_Saxena.pdf” link_option_url_new_window=”on” box_shadow_style=”preset1″ box_shadow_vertical=”0px” box_shadow_blur=”40px” box_shadow_color=”rgba(0,0,0,0.14)”]<\/p>\n

Gomes I, Ijzerman AP, Ye K, Maillet EL, Devi LA.
<\/em>
G protein-coupled receptor heteromerization: a role in allosteric modulation of ligand binding.\u00a0<\/strong><\/a>
Molecular Pharmacology. 2011 Jun;79(6):1044-52. doi: 10.1124\/mol.110.070847. Epub 2011 Mar 17.<\/p>\n

[\/et_pb_text][\/et_pb_column][et_pb_column type=”1_5″ _builder_version=”3.25″ custom_padding=”|||” custom_padding__hover=”|||”][et_pb_text _builder_version=”4.9.0″ _module_preset=”default” text_font_size=”14px” text_line_height=”1.5em” background_color=”#FFFFFF” custom_padding=”20px|20px|20px|20px|true|true” link_option_url=”https:\/\/labs.icahn.mssm.edu\/rendl-lab\/wp-content\/uploads\/sites\/292\/2020\/01\/2019_Saxena.pdf” link_option_url_new_window=”on” box_shadow_style=”preset1″ box_shadow_vertical=”0px” box_shadow_blur=”40px” box_shadow_color=”rgba(0,0,0,0.14)”]<\/p>\n

Rozenfeld R, Gupta A, Gagnidze K, Lim MP, Gomes I, Lee-Ramos D, Nieto N, Devi LA.
<\/em>
AT1R-CB\u2081R heteromerization reveals a new mechanism for the pathogenic properties of angiotensin II.\u00a0<\/strong><\/a>
EMBO J. 2011 May 3;30(12):2350-63.<\/p>\n

[\/et_pb_text][\/et_pb_column][et_pb_column type=”1_5″ _builder_version=”4.9.0″ _module_preset=”default”][et_pb_text _builder_version=”4.9.0″ _module_preset=”default” text_font_size=”14px” text_line_height=”1.5em” background_color=”#FFFFFF” custom_padding=”20px|20px|20px|20px|true|true” link_option_url=”https:\/\/labs.icahn.mssm.edu\/rendl-lab\/wp-content\/uploads\/sites\/292\/2020\/01\/2019_Saxena.pdf” link_option_url_new_window=”on” box_shadow_style=”preset1″ box_shadow_vertical=”0px” box_shadow_blur=”40px” box_shadow_color=”rgba(0,0,0,0.14)”]<\/p>\n

Rozenfeld R, Devi LA.
<\/em>
Exploring a role for heteromerization in GPCR signalling specificity.\u00a0<\/strong><\/a>
Biochemical Journal. 2011 Jan 1;433(1):11-8. Review.<\/p>\n

[\/et_pb_text][\/et_pb_column][et_pb_column type=”1_5″ _builder_version=”4.9.0″ _module_preset=”default”][et_pb_text _builder_version=”4.9.0″ _module_preset=”default” text_font_size=”14px” text_line_height=”1.5em” background_color=”#FFFFFF” custom_padding=”20px|20px|20px|20px|true|true” link_option_url=”https:\/\/labs.icahn.mssm.edu\/rendl-lab\/wp-content\/uploads\/sites\/292\/2020\/01\/2019_Saxena.pdf” link_option_url_new_window=”on” box_shadow_style=”preset1″ box_shadow_vertical=”0px” box_shadow_blur=”40px” box_shadow_color=”rgba(0,0,0,0.14)”]<\/p>\n

Gomes I, Dale CS, Casten K, Geigner MA, Gozzo FC, Ferro ES, Heimann AS, Devi LA.
<\/em>
Hemoglobin-derived peptides as novel type of bioactive signaling molecules.\u00a0<\/strong><\/a>
AAPS Journal. 2010 Dec;12(4):658-69. Epub 2010 Sep 2. Review.<\/p>\n

[\/et_pb_text][\/et_pb_column][et_pb_column type=”1_5″ _builder_version=”4.9.0″ _module_preset=”default”][et_pb_text admin_label=”Text” _builder_version=”4.9.0″ _module_preset=”default” text_font_size=”14px” text_line_height=”1.5em” background_color=”#FFFFFF” custom_padding=”20px|20px|20px|20px|true|true” link_option_url=”https:\/\/labs.icahn.mssm.edu\/rendl-lab\/wp-content\/uploads\/sites\/292\/2020\/01\/2019_Saxena.pdf” link_option_url_new_window=”on” box_shadow_style=”preset1″ box_shadow_vertical=”0px” box_shadow_blur=”40px” box_shadow_color=”rgba(0,0,0,0.14)”]<\/p>\n

Ouimet T, Orng SV, Poras H, Gagnidze K, Devi LA, Fourni\u00e9-Zaluski MC, Roques BP.
<\/em>
Identification of an endothelin-converting enzyme-2-specific fluorigenic substrate and development of an in vitro and ex vivo enzymatic assay.\u00a0<\/strong><\/a>
The Journal of Biological Chemistry. 2010 Nov 5;285(45):34390-400. Epub 2010 Aug 31.<\/p>\n

[\/et_pb_text][\/et_pb_column][\/et_pb_row][et_pb_row column_structure=”1_5,1_5,1_5,1_5,1_5″ _builder_version=”3.25″ background_size=”initial” background_position=”top_left” background_repeat=”repeat” collapsed=”on”][et_pb_column type=”1_5″ _builder_version=”3.25″ custom_padding=”|||” custom_padding__hover=”|||”][et_pb_text _builder_version=”4.9.0″ _module_preset=”default” text_font_size=”14px” text_line_height=”1.5em” background_color=”#FFFFFF” custom_padding=”20px|20px|20px|20px|true|true” link_option_url=”https:\/\/labs.icahn.mssm.edu\/rendl-lab\/wp-content\/uploads\/sites\/292\/2020\/01\/2019_Saxena.pdf” link_option_url_new_window=”on” box_shadow_style=”preset1″ box_shadow_vertical=”0px” box_shadow_blur=”40px” box_shadow_color=”rgba(0,0,0,0.14)”]<\/p>\n

LaRocca TJ, Schwarzkopf M, Altman P, Zhang S, Gupta A, Gomes I, Alvin Z, Champion HC, Haddad G, Hajjar RJ, Devi LA, Schecter AD, Tarzami ST.
<\/em>
\u03b22-Adrenergic receptor signaling in the cardiac myocyte is modulated by interactions with CXCR4.\u00a0<\/strong><\/a>
Journal of Cardiovascular Pharmacology. 2010 Nov;56(5):548-59.<\/p>\n

[\/et_pb_text][\/et_pb_column][et_pb_column type=”1_5″ _builder_version=”3.25″ custom_padding=”|||” custom_padding__hover=”|||”][et_pb_text _builder_version=”4.9.0″ _module_preset=”default” text_font_size=”14px” text_line_height=”1.5em” background_color=”#FFFFFF” custom_padding=”20px|20px|20px|20px|true|true” link_option_url=”https:\/\/labs.icahn.mssm.edu\/rendl-lab\/wp-content\/uploads\/sites\/292\/2020\/01\/2019_Saxena.pdf” link_option_url_new_window=”on” box_shadow_style=”preset1″ box_shadow_vertical=”0px” box_shadow_blur=”40px” box_shadow_color=”rgba(0,0,0,0.14)”]<\/p>\n

Williams D, Devi LA.
<\/em>
Escorts take the lead molecular chaperones as therapeutic targets.\u00a0<\/strong><\/a>
Progress in Molecular Biology and Translational Science. 2010;91:121-49. Review.<\/p>\n

[\/et_pb_text][\/et_pb_column][et_pb_column type=”1_5″ _builder_version=”4.9.0″ _module_preset=”default”][et_pb_text _builder_version=”4.9.0″ _module_preset=”default” text_font_size=”14px” text_line_height=”1.5em” background_color=”#FFFFFF” custom_padding=”20px|20px|20px|20px|true|true” link_option_url=”https:\/\/labs.icahn.mssm.edu\/rendl-lab\/wp-content\/uploads\/sites\/292\/2020\/01\/2019_Saxena.pdf” link_option_url_new_window=”on” box_shadow_style=”preset1″ box_shadow_vertical=”0px” box_shadow_blur=”40px” box_shadow_color=”rgba(0,0,0,0.14)”]<\/p>\n

Hipser C, Bushlin I, Gupta A, Gomes I, Devi LA.
<\/em>
Role of antibodies in developing drugs that target G-protein-coupled receptor dimers.\u00a0<\/strong><\/a>
Mount Sinai Journal of Medicine. 2010 Jul-Aug;77(4):374-80. Review.<\/p>\n

[\/et_pb_text][\/et_pb_column][et_pb_column type=”1_5″ _builder_version=”4.9.0″ _module_preset=”default”][et_pb_text _builder_version=”4.9.0″ _module_preset=”default” text_font_size=”14px” text_line_height=”1.5em” background_color=”#FFFFFF” custom_padding=”20px|20px|20px|20px|true|true” link_option_url=”https:\/\/labs.icahn.mssm.edu\/rendl-lab\/wp-content\/uploads\/sites\/292\/2020\/01\/2019_Saxena.pdf” link_option_url_new_window=”on” box_shadow_style=”preset1″ box_shadow_vertical=”0px” box_shadow_blur=”40px” box_shadow_color=”rgba(0,0,0,0.14)”]<\/p>\n

Gupta A, Mulder J, Gomes I, Rozenfeld R, Bushlin I, Ong E, Lim M, Maillet E, Junek M, Cahill CM, Harkany T, Devi LA.
<\/em>
Increased abundance of opioid receptor heteromers after chronic morphine administration.\u00a0<\/strong><\/a>
Science Signaling. 2010 Jul 20;3(131):ra54.<\/p>\n

[\/et_pb_text][\/et_pb_column][et_pb_column type=”1_5″ _builder_version=”4.9.0″ _module_preset=”default”][et_pb_text admin_label=”Text” _builder_version=”4.9.0″ _module_preset=”default” text_font_size=”14px” text_line_height=”1.5em” background_color=”#FFFFFF” custom_padding=”20px|20px|20px|20px|true|true” link_option_url=”https:\/\/labs.icahn.mssm.edu\/rendl-lab\/wp-content\/uploads\/sites\/292\/2020\/01\/2019_Saxena.pdf” link_option_url_new_window=”on” box_shadow_style=”preset1″ box_shadow_vertical=”0px” box_shadow_blur=”40px” box_shadow_color=”rgba(0,0,0,0.14)”]<\/p>\n

Khelashvili G, Dorff K, Shan J, Camacho-Artacho M, Skrabanek L, Vroling B, Bouvier M, Devi LA, George SR, Javitch JA, Lohse MJ, Milligan G, Neubig RR, Palczewski K, Parmentier M, Pin JP, Vriend G, Campagne F, Filizola M.
<\/em>
GPCR-OKB: the G Protein Coupled Receptor Oligomer Knowledge Base.\u00a0<\/strong><\/a>
Bioinformatics. 2010 Jul 15;26(14):1804-5. Epub 2010 May 25.<\/p>\n

[\/et_pb_text][\/et_pb_column][\/et_pb_row][et_pb_row column_structure=”1_5,1_5,1_5,1_5,1_5″ _builder_version=”3.25″ background_size=”initial” background_position=”top_left” background_repeat=”repeat” collapsed=”on”][et_pb_column type=”1_5″ _builder_version=”3.25″ custom_padding=”|||” custom_padding__hover=”|||”][et_pb_text _builder_version=”4.9.0″ _module_preset=”default” text_font_size=”14px” text_line_height=”1.5em” background_color=”#FFFFFF” custom_padding=”20px|20px|20px|20px|true|true” link_option_url=”https:\/\/labs.icahn.mssm.edu\/rendl-lab\/wp-content\/uploads\/sites\/292\/2020\/01\/2019_Saxena.pdf” link_option_url_new_window=”on” box_shadow_style=”preset1″ box_shadow_vertical=”0px” box_shadow_blur=”40px” box_shadow_color=”rgba(0,0,0,0.14)”]<\/p>\n

Morgan DJ, Wei S, Gomes I, Czyzyk T, Mzhavia N, Pan H, Devi LA, Fricker LD, Pintar JE.
<\/em>
The propeptide precursor proSAAS is involved in fetal neuropeptide processing and body weight regulation.\u00a0<\/strong><\/a>
Journal of Neurochemistry. 2010 Jun;113(5):1275-84. Epub 2010 Mar 26.<\/p>\n

[\/et_pb_text][\/et_pb_column][et_pb_column type=”1_5″ _builder_version=”3.25″ custom_padding=”|||” custom_padding__hover=”|||”][et_pb_text _builder_version=”4.9.0″ _module_preset=”default” text_font_size=”14px” text_line_height=”1.5em” background_color=”#FFFFFF” custom_padding=”20px|20px|20px|20px|true|true” link_option_url=”https:\/\/labs.icahn.mssm.edu\/rendl-lab\/wp-content\/uploads\/sites\/292\/2020\/01\/2019_Saxena.pdf” link_option_url_new_window=”on” box_shadow_style=”preset1″ box_shadow_vertical=”0px” box_shadow_blur=”40px” box_shadow_color=”rgba(0,0,0,0.14)”]<\/p>\n

Rozenfeld R, Devi LA.
<\/em>
Receptor heteromerization and drug discovery.\u00a0<\/strong><\/a>
Trends in Pharmacological Sciences. 2010 Mar;31(3):124-30. Epub 2010 Jan 7.<\/p>\n

[\/et_pb_text][\/et_pb_column][et_pb_column type=”1_5″ _builder_version=”4.9.0″ _module_preset=”default”][et_pb_text _builder_version=”4.9.0″ _module_preset=”default” text_font_size=”14px” text_line_height=”1.5em” background_color=”#FFFFFF” custom_padding=”20px|20px|20px|20px|true|true” link_option_url=”https:\/\/labs.icahn.mssm.edu\/rendl-lab\/wp-content\/uploads\/sites\/292\/2020\/01\/2019_Saxena.pdf” link_option_url_new_window=”on” box_shadow_style=”preset1″ box_shadow_vertical=”0px” box_shadow_blur=”40px” box_shadow_color=”rgba(0,0,0,0.14)”]<\/p>\n

Ramos-Ortolaza DL, Bushlin I, Abul-Husn N, Annangudi SP, Sweedler J, Devi LA.
<\/em>
Quantitative neuroproteomics of the synapse.\u00a0<\/strong><\/a>
Methods in Molecular Biology. 2010;615:227-46.<\/p>\n

[\/et_pb_text][\/et_pb_column][et_pb_column type=”1_5″ _builder_version=”4.9.0″ _module_preset=”default”][et_pb_text _builder_version=”4.9.0″ _module_preset=”default” text_font_size=”14px” text_line_height=”1.5em” background_color=”#FFFFFF” custom_padding=”20px|20px|20px|20px|true|true” link_option_url=”https:\/\/labs.icahn.mssm.edu\/rendl-lab\/wp-content\/uploads\/sites\/292\/2020\/01\/2019_Saxena.pdf” link_option_url_new_window=”on” box_shadow_style=”preset1″ box_shadow_vertical=”0px” box_shadow_blur=”40px” box_shadow_color=”rgba(0,0,0,0.14)”]<\/p>\n

Mor\u00f3n JA, Gullapalli S, Taylor C, Gupta A, Gomes I, Devi LA.
<\/em>
Modulation of opiate-related signaling molecules in morphine-dependent conditioned behavior: conditioned place preference to morphine induces CREB phosphorylation.\u00a0<\/strong><\/a>
Neuropsychopharmacology. 2010 Mar;35(4):955-66. Epub 2009 Dec 2.<\/p>\n

[\/et_pb_text][\/et_pb_column][et_pb_column type=”1_5″ _builder_version=”4.9.0″ _module_preset=”default”][et_pb_text admin_label=”Text” _builder_version=”4.9.0″ _module_preset=”default” text_font_size=”14px” text_line_height=”1.5em” background_color=”#FFFFFF” custom_padding=”20px|20px|20px|20px|true|true” link_option_url=”https:\/\/labs.icahn.mssm.edu\/rendl-lab\/wp-content\/uploads\/sites\/292\/2020\/01\/2019_Saxena.pdf” link_option_url_new_window=”on” box_shadow_style=”preset1″ box_shadow_vertical=”0px” box_shadow_blur=”40px” box_shadow_color=”rgba(0,0,0,0.14)”]<\/p>\n

Bushlin I, Rozenfeld R, Devi LA.
<\/em>
Cannabinoid-opioid interactions during neuropathic pain and analgesia.\u00a0<\/strong><\/a>
Current Opinion in Pharmacology. 2010 Feb;10(1):80-6. Epub 2009 Oct 25. Review.<\/p>\n

[\/et_pb_text][\/et_pb_column][\/et_pb_row][et_pb_row column_structure=”1_5,1_5,1_5,1_5,1_5″ disabled_on=”on|on|on” _builder_version=”3.25″ background_size=”initial” background_position=”top_left” background_repeat=”repeat” disabled=”on” collapsed=”on”][et_pb_column type=”1_5″ _builder_version=”3.25″ custom_padding=”|||” custom_padding__hover=”|||”][et_pb_text _builder_version=”4.9.0″ _module_preset=”default” text_font_size=”14px” text_line_height=”1.5em” background_color=”#FFFFFF” custom_padding=”20px|20px|20px|20px|true|true” link_option_url=”https:\/\/labs.icahn.mssm.edu\/rendl-lab\/wp-content\/uploads\/sites\/292\/2020\/01\/2019_Saxena.pdf” link_option_url_new_window=”on” box_shadow_style=”preset1″ box_shadow_vertical=”0px” box_shadow_blur=”40px” box_shadow_color=”rgba(0,0,0,0.14)”]<\/p>\n

Rezza A, Sennett R, Rendl M.
<\/em>
Wdr5 mediates self-renewal and reprogramming via the embryonic stem cell core transcriptional network.<\/strong>
Current Topics in Developmental Biology 2014, 107C:333-372.<\/p>\n

Download<\/a><\/strong><\/p>\n

[\/et_pb_text][\/et_pb_column][et_pb_column type=”1_5″ _builder_version=”3.25″ custom_padding=”|||” custom_padding__hover=”|||”][et_pb_text _builder_version=”4.9.0″ _module_preset=”default” text_font_size=”14px” text_line_height=”1.5em” background_color=”#FFFFFF” custom_padding=”20px|20px|20px|20px|true|true” link_option_url=”https:\/\/labs.icahn.mssm.edu\/rendl-lab\/wp-content\/uploads\/sites\/292\/2020\/01\/2019_Saxena.pdf” link_option_url_new_window=”on” box_shadow_style=”preset1″ box_shadow_vertical=”0px” box_shadow_blur=”40px” box_shadow_color=”rgba(0,0,0,0.14)”]<\/p>\n

Sennett R, Rezza A, Dauber KL, Clavel C, Rendl M.
<\/em>
Cxcr4 is transiently expressed in both epithelial and mesenchymal compartment formation.\u00a0<\/strong>
Experimental Dermatology\u00a0<\/em>2014, 23:748-50<\/p>\n

Download<\/a><\/strong><\/p>\n

[\/et_pb_text][\/et_pb_column][et_pb_column type=”1_5″ _builder_version=”4.9.0″ _module_preset=”default”][et_pb_text _builder_version=”4.9.0″ _module_preset=”default” text_font_size=”14px” text_line_height=”1.5em” background_color=”#FFFFFF” custom_padding=”20px|20px|20px|20px|true|true” link_option_url=”https:\/\/labs.icahn.mssm.edu\/rendl-lab\/wp-content\/uploads\/sites\/292\/2020\/01\/2019_Saxena.pdf” link_option_url_new_window=”on” box_shadow_style=”preset1″ box_shadow_vertical=”0px” box_shadow_blur=”40px” box_shadow_color=”rgba(0,0,0,0.14)”]<\/p>\n

Tsai SY*, Sennett R*, Rezza A, Clavel C, Grisanti L, Zemla R, Najam S, Rendl M.
<\/em>
Wnt\/\u03b2-catenin signaling in dermal condensates is required for hair follicle formation.\u00a0<\/strong>
Developmental Biology 2014, 385:179-88.<\/p>\n

Download<\/a><\/strong><\/p>\n

[\/et_pb_text][\/et_pb_column][et_pb_column type=”1_5″ _builder_version=”4.9.0″ _module_preset=”default”][et_pb_text _builder_version=”4.9.0″ _module_preset=”default” text_font_size=”14px” text_line_height=”1.5em” background_color=”#FFFFFF” custom_padding=”20px|20px|20px|20px|true|true” link_option_url=”https:\/\/labs.icahn.mssm.edu\/rendl-lab\/wp-content\/uploads\/sites\/292\/2020\/01\/2019_Saxena.pdf” link_option_url_new_window=”on” box_shadow_style=”preset1″ box_shadow_vertical=”0px” box_shadow_blur=”40px” box_shadow_color=”rgba(0,0,0,0.14)”]<\/p>\n

Grisanti L, Rezza A, Clavel C, Sennett R, Rendl M.
<\/em>
Enpp2\/Autotaxin in Dermal Papilla Precursors is Dispensable for Hair Follicle Morphogenesis.\u00a0<\/strong>
Journal of Investigative Dermatology\u00a0<\/em>2013, 133:2332-9.<\/p>\n

Download<\/a><\/strong><\/p>\n

[\/et_pb_text][\/et_pb_column][et_pb_column type=”1_5″ _builder_version=”4.9.0″ _module_preset=”default”][et_pb_text admin_label=”Text” _builder_version=”4.9.0″ _module_preset=”default” text_font_size=”14px” text_line_height=”1.5em” background_color=”#FFFFFF” custom_padding=”20px|20px|20px|20px|true|true” link_option_url=”https:\/\/labs.icahn.mssm.edu\/rendl-lab\/wp-content\/uploads\/sites\/292\/2020\/01\/2019_Saxena.pdf” link_option_url_new_window=”on” box_shadow_style=”preset1″ box_shadow_vertical=”0px” box_shadow_blur=”40px” box_shadow_color=”rgba(0,0,0,0.14)”]<\/p>\n

Nguyen H, Merrill BJ, Polak L, Nikolova M, Rendl M, Shaver TM, Pasolli HA, Fuchs E.
<\/em>
Mesenchymal-epithelial interactions during hair follicle morphogenesis.\u00a0<\/strong>
Seminars in Cell Developmental Biology2012, 23:917-27<\/p>\n

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Icahn School of Medicine
at Mount Sinai
One Gustave L. Levy Place
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New York, NY 10029
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Office Location<\/strong>
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Annenberg Building, Room 19-86
1468 Madison Avenue
New York, NY 10029<\/p>\n

Mailing Address <\/strong><\/p>\n

Icahn School of Medicine at Mount Sinai
Department of Pharmacology and Systems Therapeutics
One Gustave L. Levy Place
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[\/et_pb_text][\/et_pb_column][\/et_pb_row][\/et_pb_section]<\/p>\n","protected":false},"excerpt":{"rendered":"

PublicationsOur current research focuses on birth of the hair follicle niche, growth control and regeneration, and tissue regression and reorganization.Sierra S, Gomes I, Devi LAClass A GPCRs: Cannabinoid and opioid receptor heteromers Chapter 7. G-Protein-Coupled Receptor Dimers. 2017. doi:10.1007\/978-3-319-60174-8Margolis EB, Fujita W, Devi LA, Fields HLTwo delta opioid receptor subtypes are functional in single ventral […]<\/p>\n","protected":false},"author":545,"featured_media":0,"parent":0,"menu_order":4,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_et_pb_use_builder":"on","_et_pb_old_content":"","_et_gb_content_width":"","inline_featured_image":false,"footnotes":""},"class_list":["post-2494","page","type-page","status-publish","hentry"],"aioseo_notices":[],"_links":{"self":[{"href":"https:\/\/labs.icahn.mssm.edu\/devilab\/wp-json\/wp\/v2\/pages\/2494","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/labs.icahn.mssm.edu\/devilab\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/labs.icahn.mssm.edu\/devilab\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/labs.icahn.mssm.edu\/devilab\/wp-json\/wp\/v2\/users\/545"}],"replies":[{"embeddable":true,"href":"https:\/\/labs.icahn.mssm.edu\/devilab\/wp-json\/wp\/v2\/comments?post=2494"}],"version-history":[{"count":5,"href":"https:\/\/labs.icahn.mssm.edu\/devilab\/wp-json\/wp\/v2\/pages\/2494\/revisions"}],"predecessor-version":[{"id":4798,"href":"https:\/\/labs.icahn.mssm.edu\/devilab\/wp-json\/wp\/v2\/pages\/2494\/revisions\/4798"}],"wp:attachment":[{"href":"https:\/\/labs.icahn.mssm.edu\/devilab\/wp-json\/wp\/v2\/media?parent=2494"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}