[et_pb_section fb_built=”1″ admin_label=”1 (Carousel)” _builder_version=”4.9.0″ _module_preset=”default” background_color=”#00aeef” background_image=”https:\/\/labs.icahn.mssm.edu\/davislab\/wp-content\/uploads\/sites\/547\/2022\/10\/Background-2.png” parallax=”on” custom_padding=”||||false|false” bottom_divider_style=”slant2″ bottom_divider_color=”#FFFFFF” bottom_divider_height=”11vw” bottom_divider_arrangement=”above_content” global_module=”1300″ locked=”off” collapsed=”off” global_colors_info=”{}”][et_pb_row column_structure=”1_2,1_2″ _builder_version=”4.16″ _module_preset=”default” background_color=”RGBA(0,0,0,0)” border_color_all=”RGBA(0,0,0,0)” global_colors_info=”{}”][et_pb_column type=”1_2″ _builder_version=”4.16″ _module_preset=”default” custom_padding=”10%||8vw||false|false” custom_padding_tablet=”0vw||0vw||true|false” custom_padding_phone=”” custom_padding_last_edited=”on|tablet” global_colors_info=”{}”][et_pb_text _builder_version=”4.16″ _module_preset=”b3e3ff14-5f5c-4608-8ecf-1885ce3da7aa” header_font=”||||||||” header_text_color=”#FFFFFF” header_font_size=”48px” header_line_height=”60px” custom_margin=”||10px||false|false” header_font_size_tablet=”40px” header_font_size_phone=”24px” header_font_size_last_edited=”on|desktop” global_colors_info=”{}”]<\/p>\n
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Our current research\u00a0spans many domains of medicine and psychiatry, ranging from neurodevelopmental disorders to women\u2019s health. We employ a population level approach to investigate the genetic basis of a wide range of complex health conditions, diseases, and common traits.<\/span><\/p>\n [\/et_pb_text][\/et_pb_column][et_pb_column type=”1_2″ _builder_version=”4.16″ _module_preset=”default” background_color=”RGBA(0,0,0,0)” global_colors_info=”{}”][et_pb_image src=”https:\/\/labs.icahn.mssm.edu\/davislab\/wp-content\/uploads\/sites\/547\/2025\/05\/IMG_0216-scaled.jpg” title_text=”IMG_0216″ align=”center” force_fullwidth=”on” _builder_version=”4.16″ _module_preset=”default” custom_margin=”80px||||false|false” custom_padding=”20px||||false|false” global_colors_info=”{}”][\/et_pb_image][\/et_pb_column][\/et_pb_row][\/et_pb_section][et_pb_section fb_built=”1″ _builder_version=”4.16″ _module_preset=”default” global_colors_info=”{}”][et_pb_row _builder_version=”4.16″ _module_preset=”default” global_colors_info=”{}”][et_pb_column type=”4_4″ _builder_version=”4.16″ _module_preset=”default” global_colors_info=”{}”][et_pb_text _builder_version=”4.16″ _module_preset=”default” text_font=”Encode Sans||||||||” text_font_size=”35px” header_text_align=”center” header_text_color=”#221F72″ header_font_size=”40px” global_colors_info=”{}”]<\/p>\n [\/et_pb_text][\/et_pb_column][\/et_pb_row][et_pb_row _builder_version=”4.16″ _module_preset=”default” global_colors_info=”{}”][et_pb_column type=”4_4″ _builder_version=”4.16″ _module_preset=”default” global_colors_info=”{}”][et_pb_text _builder_version=”4.16″ _module_preset=”default” global_colors_info=”{}”]<\/p>\n In the Davis Lab, we are interested in the genomics of a wide range of complex phenotypes. For most complex traits, much of the genetic liability is distributed throughout the genome and therefore each individual single nucleotide polymorphism (SNP) explains a very small proportion of the phenotypic variance (i.e., heritability) observed through traditional twin and family-based methods. While the contribution of each individual variant is small, for many complex or \u201cpolygenic\u201d traits, the cumulative effect of these contributory common SNPs is substantial. Additionally, complex traits are also influenced by rare genetic variants, and environmental factors. Our research\u00a0aims to understand how polygenic risk, rare variant risk, and environment interact to result in complex traits. We study a wide range of traits\u00a0including psychiatric and endocrine phenotypes and are particularly interested in understanding the genetics underlying the richness of neurodiversity in human populations.<\/span><\/p>\n [\/et_pb_text][\/et_pb_column][\/et_pb_row][et_pb_row _builder_version=”4.27.4″ _module_preset=”default” global_colors_info=”{}”][et_pb_column type=”4_4″ _builder_version=”4.27.4″ _module_preset=”default” global_colors_info=”{}”][et_pb_button button_url=”https:\/\/labs.icahn.mssm.edu\/davislab\/team\/join-us\/” button_text=”Join Us!” button_alignment=”center” _builder_version=”4.27.4″ _module_preset=”default” hover_enabled=”0″ global_colors_info=”{}” sticky_enabled=”0″][\/et_pb_button][\/et_pb_column][\/et_pb_row][\/et_pb_section][et_pb_section fb_built=”1″ admin_label=”Two Column Title Over Text Next to Image – Section 5″ module_class=”section5_two_col_title_over_txt_next_to_img” _builder_version=”4.16″ _module_preset=”default” locked=”off” collapsed=”off” 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max_width=”100%” height=”1000px” hover_enabled=”0″ global_colors_info=”{}” sticky_enabled=”0″][\/et_pb_gallery][\/et_pb_column][\/et_pb_row][\/et_pb_section][et_pb_section fb_built=”1″ disabled_on=”off|off|off” admin_label=”Footer Fullwidth – Section 13″ module_class=”footer-section” _builder_version=”4.9.0″ background_color=”#221F72″ background_image=”https:\/\/labs.icahn.mssm.edu\/davislab\/wp-content\/uploads\/sites\/547\/2022\/10\/Rectangle-3.png” max_width=”100%” max_width_tablet=”” max_width_phone=”” max_width_last_edited=”on|phone” module_alignment=”center” custom_margin=”100px|||176px|false|false” custom_padding=”3px|0px|0px|0px|false|false” animation_style=”slide” animation_direction=”bottom” animation_intensity_slide=”14%” animation_starting_opacity=”100%” global_module=”3741″ saved_tabs=”all” locked=”off” collapsed=”on” global_colors_info=”{}”][et_pb_row _builder_version=”4.16″ background_color=”RGBA(0,0,0,0)” background_color_gradient_direction=”38deg” 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global_colors_info=”{}”]<\/p>\n Lab Address <\/strong> [\/et_pb_text][\/et_pb_column][\/et_pb_row][\/et_pb_section]<\/p>\n","protected":false},"excerpt":{"rendered":" Welcome to the Davis Lab!Our current research\u00a0spans many domains of medicine and psychiatry, ranging from neurodevelopmental disorders to women\u2019s health. We employ a population level approach to investigate the genetic basis of a wide range of complex health conditions, diseases, and common traits.What we do in the Davis LabIn the Davis Lab, we are interested […]<\/p>\n","protected":false},"author":545,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_et_pb_use_builder":"on","_et_pb_old_content":"","_et_gb_content_width":"","inline_featured_image":false,"footnotes":""},"class_list":["post-1349","page","type-page","status-publish","hentry"],"aioseo_notices":[],"_links":{"self":[{"href":"https:\/\/labs.icahn.mssm.edu\/davislab\/wp-json\/wp\/v2\/pages\/1349","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/labs.icahn.mssm.edu\/davislab\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/labs.icahn.mssm.edu\/davislab\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/labs.icahn.mssm.edu\/davislab\/wp-json\/wp\/v2\/users\/545"}],"replies":[{"embeddable":true,"href":"https:\/\/labs.icahn.mssm.edu\/davislab\/wp-json\/wp\/v2\/comments?post=1349"}],"version-history":[{"count":40,"href":"https:\/\/labs.icahn.mssm.edu\/davislab\/wp-json\/wp\/v2\/pages\/1349\/revisions"}],"predecessor-version":[{"id":5016,"href":"https:\/\/labs.icahn.mssm.edu\/davislab\/wp-json\/wp\/v2\/pages\/1349\/revisions\/5016"}],"wp:attachment":[{"href":"https:\/\/labs.icahn.mssm.edu\/davislab\/wp-json\/wp\/v2\/media?parent=1349"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}What we do in the Davis Lab<\/strong><\/span><\/h1>\n
Latest News in the Davis Lab!<\/span><\/h3>\n
\n
<\/a><\/span>Recent News and Gallery
Team and Alumni<\/a>
<\/a>Research<\/a>
Accessibility<\/a><\/span><\/p>\n
<\/strong>lea.davis@mssm.edu<\/p>\n
3 E. 101st Street
The Hamilton and Amabel James Center for Artificial Intelligence
New York, NY 10029<\/p>\n