
{"id":2494,"date":"2022-12-20T11:44:55","date_gmt":"2022-12-20T16:44:55","guid":{"rendered":"https:\/\/labs.icahn.mssm.edu\/design\/?page_id=2494"},"modified":"2025-12-18T16:04:32","modified_gmt":"2025-12-18T21:04:32","slug":"publications","status":"publish","type":"page","link":"https:\/\/labs.icahn.mssm.edu\/dardiklab\/publications\/","title":{"rendered":"Publications"},"content":{"rendered":"<p>[et_pb_section fb_built=&#8221;1&#8243; admin_label=&#8221;Fullwidth Header &#8211; Background Title Description &#8211; no slider &#8211; Section 1 &#8221; module_class=&#8221;header-title-desciption-no-slider-section1&#8243; _builder_version=&#8221;4.16&#8243; _module_preset=&#8221;default&#8221; background_color=&#8221;rgba(0,174,239,0.09)&#8221; background_enable_color=&#8221;off&#8221; background_image=&#8221;https:\/\/labs.icahn.mssm.edu\/dardiklab2\/wp-content\/uploads\/sites\/616\/2022\/07\/ai-002-1.jpg&#8221; parallax=&#8221;on&#8221; custom_padding=&#8221;||||false|false&#8221; bottom_divider_style=&#8221;ramp2&#8243; bottom_divider_color=&#8221;#FFFFFF&#8221; bottom_divider_height=&#8221;11vw&#8221; bottom_divider_arrangement=&#8221;above_content&#8221; saved_tabs=&#8221;all&#8221; locked=&#8221;off&#8221; collapsed=&#8221;on&#8221; global_colors_info=&#8221;{}&#8221;][et_pb_row column_structure=&#8221;1_2,1_2&#8243; _builder_version=&#8221;4.16&#8243; _module_preset=&#8221;default&#8221; background_color=&#8221;RGBA(0,0,0,0)&#8221; border_color_all=&#8221;RGBA(0,0,0,0)&#8221; global_colors_info=&#8221;{}&#8221;][et_pb_column type=&#8221;1_2&#8243; _builder_version=&#8221;4.16&#8243; _module_preset=&#8221;default&#8221; custom_padding=&#8221;10%||8vw||false|false&#8221; custom_padding_tablet=&#8221;0vw||0vw||true|false&#8221; custom_padding_phone=&#8221;&#8221; custom_padding_last_edited=&#8221;on|tablet&#8221; global_colors_info=&#8221;{}&#8221;][et_pb_text admin_label=&#8221;Text &#8211; Title&#8221; _builder_version=&#8221;4.16&#8243; _module_preset=&#8221;b3e3ff14-5f5c-4608-8ecf-1885ce3da7aa&#8221; header_font=&#8221;||||||||&#8221; header_text_color=&#8221;#FFFFFF&#8221; header_font_size=&#8221;48px&#8221; header_line_height=&#8221;60px&#8221; custom_margin=&#8221;||10px||false|false&#8221; header_font_size_tablet=&#8221;40px&#8221; header_font_size_phone=&#8221;24px&#8221; header_font_size_last_edited=&#8221;on|desktop&#8221; global_colors_info=&#8221;{}&#8221;]<\/p>\n<h1><strong>Publications<\/strong><\/h1>\n<p>[\/et_pb_text][et_pb_text admin_label=&#8221;Text &#8211; Description&#8221; _builder_version=&#8221;4.16&#8243; _module_preset=&#8221;da86b6f0-f83c-4c7c-bdd8-3019777ddffe&#8221; text_font=&#8221;||||||||&#8221; text_text_color=&#8221;#FFFFFF&#8221; text_font_size=&#8221;20px&#8221; text_line_height=&#8221;32px&#8221; custom_padding=&#8221;2px|||||&#8221; text_font_size_tablet=&#8221;15px&#8221; text_font_size_phone=&#8221;14px&#8221; text_font_size_last_edited=&#8221;on|desktop&#8221; global_colors_info=&#8221;{}&#8221;]<\/p>\n<p>Our current research focuses on the mechnism of arteriovenous fistula failure<\/p>\n<p>[\/et_pb_text][\/et_pb_column][et_pb_column type=&#8221;1_2&#8243; _builder_version=&#8221;4.16&#8243; _module_preset=&#8221;default&#8221; background_color=&#8221;RGBA(0,0,0,0)&#8221; global_colors_info=&#8221;{}&#8221;][\/et_pb_column][\/et_pb_row][\/et_pb_section][et_pb_section fb_built=&#8221;1&#8243; disabled_on=&#8221;off|off|off&#8221; admin_label=&#8221;Section 28 &#8211; Blog Style Publications&#8221; module_class=&#8221;section28_blog_style_publications&#8221; _builder_version=&#8221;4.9.0&#8243; background_color=&#8221;#FFFFFF&#8221; background_image=&#8221;https:\/\/labs.icahn.mssm.edu\/dardiklab2\/wp-content\/uploads\/sites\/616\/2022\/10\/Background-1.png&#8221; parallax=&#8221;on&#8221; parallax_method=&#8221;off&#8221; custom_padding=&#8221;100px||||false|false&#8221; global_module=&#8221;2511&#8243; saved_tabs=&#8221;all&#8221; locked=&#8221;off&#8221; collapsed=&#8221;off&#8221; global_colors_info=&#8221;{}&#8221;][et_pb_row column_structure=&#8221;1_3,1_3,1_3&#8243; _builder_version=&#8221;4.16&#8243; background_size=&#8221;initial&#8221; background_position=&#8221;top_left&#8221; background_repeat=&#8221;repeat&#8221; global_colors_info=&#8221;{}&#8221;][et_pb_column type=&#8221;1_3&#8243; _builder_version=&#8221;4.16&#8243; custom_padding=&#8221;|||&#8221; global_colors_info=&#8221;{}&#8221; custom_padding__hover=&#8221;|||&#8221;][et_pb_text _builder_version=&#8221;4.27.4&#8243; _module_preset=&#8221;default&#8221; text_font_size=&#8221;14px&#8221; text_line_height=&#8221;1.5em&#8221; background_color=&#8221;#FFFFFF&#8221; custom_padding=&#8221;20px|20px|20px|20px|true|true&#8221; link_option_url=&#8221;https:\/\/labs.icahn.mssm.edu\/rendl-lab\/wp-content\/uploads\/sites\/292\/2020\/01\/2019_Saxena.pdf&#8221; link_option_url_new_window=&#8221;on&#8221; box_shadow_style=&#8221;preset1&#8243; box_shadow_vertical=&#8221;0px&#8221; box_shadow_blur=&#8221;40px&#8221; box_shadow_color=&#8221;rgba(0,0,0,0.14)&#8221; global_colors_info=&#8221;{}&#8221;]<\/p>\n<p><em>Aoyagi Y, Schwartz AW, Li Z, Bai H, Ho B, Lazcano-Etchebarne C, Gonzalez L, Ohashi Y, Kano M, Yatsula B, Ochoa Chaar CI, Martin K, Vazquez-Padron R, Dai G, Dardik A. Sox17 mediates venous adaptive remodeling after arteriovenous fistula creation. JVS Vasc Sci. 2025 Aug 28;6:100392. doi: 10.1016\/j.jvssci.2025.100392. PMID: 41127450; PMCID: PMC12538405.<br \/><\/em><\/p>\n<p><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/41127450\/\">Download<\/a><\/p>\n<p>[\/et_pb_text][\/et_pb_column][et_pb_column type=&#8221;1_3&#8243; _builder_version=&#8221;4.16&#8243; custom_padding=&#8221;|||&#8221; global_colors_info=&#8221;{}&#8221; custom_padding__hover=&#8221;|||&#8221;][et_pb_text _builder_version=&#8221;4.27.4&#8243; _module_preset=&#8221;default&#8221; text_font_size=&#8221;14px&#8221; text_line_height=&#8221;1.5em&#8221; background_color=&#8221;#FFFFFF&#8221; custom_padding=&#8221;20px|20px|20px|20px|true|true&#8221; link_option_url=&#8221;https:\/\/labs.icahn.mssm.edu\/rendl-lab\/wp-content\/uploads\/sites\/292\/2020\/01\/2019_Saxena.pdf&#8221; link_option_url_new_window=&#8221;on&#8221; box_shadow_style=&#8221;preset1&#8243; box_shadow_vertical=&#8221;0px&#8221; box_shadow_blur=&#8221;40px&#8221; box_shadow_color=&#8221;rgba(0,0,0,0.14)&#8221; global_colors_info=&#8221;{}&#8221;]<\/p>\n<p><em>Gonzalez LA, Zhang W, Bai H, Taniguchi R, Ramachandra AB, Jovin DG, Ohashi Y, Nguyen M, Thaxton C, Yatsula B, Vazquez-Padron RI, Humphrey JD, Martin KA, Kyriakides TR, Dardik A. Sustained tenascin-C expression drives neointimal hyperplasia and promotes aortocaval fistula failure. Am J Physiol Heart Circ Physiol. 2025 Jun 1;328(6):H1147-H1167. doi: 10.1152\/ajpheart.00661.2024. Epub 2025 Apr 17. PMID: 40247455; PMCID: PMC12150301.<\/em><\/p>\n<p><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/40247455\/\">download<\/a><\/p>\n<p>[\/et_pb_text][\/et_pb_column][et_pb_column type=&#8221;1_3&#8243; _builder_version=&#8221;4.16&#8243; _module_preset=&#8221;default&#8221; global_colors_info=&#8221;{}&#8221;][et_pb_text _builder_version=&#8221;4.27.4&#8243; _module_preset=&#8221;default&#8221; text_font_size=&#8221;14px&#8221; text_line_height=&#8221;1.5em&#8221; background_color=&#8221;#FFFFFF&#8221; custom_padding=&#8221;20px|20px|20px|20px|true|true&#8221; link_option_url=&#8221;https:\/\/labs.icahn.mssm.edu\/rendl-lab\/wp-content\/uploads\/sites\/292\/2020\/01\/2019_Saxena.pdf&#8221; link_option_url_new_window=&#8221;on&#8221; box_shadow_style=&#8221;preset1&#8243; box_shadow_vertical=&#8221;0px&#8221; box_shadow_blur=&#8221;40px&#8221; box_shadow_color=&#8221;rgba(0,0,0,0.14)&#8221; global_colors_info=&#8221;{}&#8221;]<\/p>\n<p>Zhang W, Gonzalez L, Li X, Bai H, Li Z, Taniguchi R, Langford J, Ohashi Y, Thaxton C, Aoyagi Y, Yatsula B, Martin KA, Goodwin J, Tellides G, Long X, Shu C, Dardik A. Endothelial TGF-\u03b2 Signaling Regulates Endothelial-Mesenchymal Transition During Arteriovenous Fistula Remodeling in Mice With Chronic Kidney Disease. Arterioscler Thromb Vasc Biol. 2024 Dec;44(12):2509-2526. doi: 10.1161\/ATVBAHA.124.320933. Epub 2024 Sep 19. PMID: 39297205; PMCID: PMC11593991.<\/p>\n<p><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/39297205\/\">download<\/a><\/p>\n<p>[\/et_pb_text][\/et_pb_column][\/et_pb_row][et_pb_row column_structure=&#8221;1_3,1_3,1_3&#8243; _builder_version=&#8221;4.16&#8243; background_size=&#8221;initial&#8221; background_position=&#8221;top_left&#8221; background_repeat=&#8221;repeat&#8221; global_colors_info=&#8221;{}&#8221;][et_pb_column type=&#8221;1_3&#8243; _builder_version=&#8221;4.16&#8243; custom_padding=&#8221;|||&#8221; global_colors_info=&#8221;{}&#8221; custom_padding__hover=&#8221;|||&#8221;][et_pb_text _builder_version=&#8221;4.27.4&#8243; _module_preset=&#8221;default&#8221; text_font_size=&#8221;14px&#8221; text_line_height=&#8221;1.5em&#8221; background_color=&#8221;#FFFFFF&#8221; custom_padding=&#8221;20px|20px|20px|20px|true|true&#8221; link_option_url=&#8221;https:\/\/labs.icahn.mssm.edu\/rendl-lab\/wp-content\/uploads\/sites\/292\/2020\/01\/2019_Saxena.pdf&#8221; link_option_url_new_window=&#8221;on&#8221; box_shadow_style=&#8221;preset1&#8243; box_shadow_vertical=&#8221;0px&#8221; box_shadow_blur=&#8221;40px&#8221; box_shadow_color=&#8221;rgba(0,0,0,0.14)&#8221; global_colors_info=&#8221;{}&#8221;]<\/p>\n<p>Bai H, Li Z, Zhang W, Thaxton C, Ohashi Y, Gonzalez L, Kano M, Yatsula B, Hwa J, Dardik A. Early thrombus formation is required for eccentric and heterogeneous neointimal hyperplasia under disturbed flow. J Thromb Haemost. 2024 Dec;22(12):3614-3628. doi: 10.1016\/j.jtha.2024.07.028. Epub 2024 Aug 21. PMID: 39173878; PMCID: PMC11608155.<\/p>\n<p><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/39173878\/\">download<\/a><\/p>\n<p>[\/et_pb_text][\/et_pb_column][et_pb_column type=&#8221;1_3&#8243; _builder_version=&#8221;4.16&#8243; custom_padding=&#8221;|||&#8221; global_colors_info=&#8221;{}&#8221; custom_padding__hover=&#8221;|||&#8221;][et_pb_text _builder_version=&#8221;4.27.4&#8243; _module_preset=&#8221;default&#8221; text_font_size=&#8221;14px&#8221; text_line_height=&#8221;1.5em&#8221; background_color=&#8221;#FFFFFF&#8221; custom_padding=&#8221;20px|20px|20px|20px|true|true&#8221; link_option_url=&#8221;https:\/\/labs.icahn.mssm.edu\/rendl-lab\/wp-content\/uploads\/sites\/292\/2020\/01\/2019_Saxena.pdf&#8221; link_option_url_new_window=&#8221;on&#8221; box_shadow_style=&#8221;preset1&#8243; box_shadow_vertical=&#8221;0px&#8221; box_shadow_blur=&#8221;40px&#8221; box_shadow_color=&#8221;rgba(0,0,0,0.14)&#8221; global_colors_info=&#8221;{}&#8221;]<\/p>\n<p>Bai H, Varsanik MA, Thaxton C, Ohashi Y, Gonzalez L, Zhang W, Aoyagi Y, Kano M, Yatsula B, Li Z, Pocivavsek L, Dardik A. Disturbed flow in the juxta-anastomotic area of an arteriovenous fistula correlates with endothelial loss, acute thrombus formation, and neointimal hyperplasia. Am J Physiol Heart Circ Physiol. 2024 Jun 1;326(6):H1446-H1461. doi: 10.1152\/ajpheart.00054.2024. Epub 2024 Apr 5. PMID: 38578237; PMCID: PMC11380968.<\/p>\n<p><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/38578237\/\">download<\/a><\/p>\n<p>[\/et_pb_text][\/et_pb_column][et_pb_column type=&#8221;1_3&#8243; _builder_version=&#8221;4.16&#8243; _module_preset=&#8221;default&#8221; global_colors_info=&#8221;{}&#8221;][et_pb_text _builder_version=&#8221;4.27.4&#8243; _module_preset=&#8221;default&#8221; text_font_size=&#8221;14px&#8221; text_line_height=&#8221;1.5em&#8221; background_color=&#8221;#FFFFFF&#8221; custom_padding=&#8221;20px|20px|20px|20px|true|true&#8221; link_option_url=&#8221;https:\/\/labs.icahn.mssm.edu\/rendl-lab\/wp-content\/uploads\/sites\/292\/2020\/01\/2019_Saxena.pdf&#8221; link_option_url_new_window=&#8221;on&#8221; box_shadow_style=&#8221;preset1&#8243; box_shadow_vertical=&#8221;0px&#8221; box_shadow_blur=&#8221;40px&#8221; box_shadow_color=&#8221;rgba(0,0,0,0.14)&#8221; global_colors_info=&#8221;{}&#8221;]<\/p>\n<p><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/?term=alan+dardik&amp;sort=date\"><strong><i>Full publications<\/i><\/strong><\/a><\/p>\n<p>&nbsp;<\/p>\n<p>[\/et_pb_text][\/et_pb_column][\/et_pb_row][\/et_pb_section][et_pb_section fb_built=&#8221;1&#8243; 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Levy Place<br \/>Annenberg<br \/>New York, NY 10029<\/p>\n<p><strong>Mailing Address <\/strong><\/p>\n<p>Lab Name<br \/> Icahn School of Medicine <br \/>at Mount Sinai<br \/><span style=\"font-size: 16px\">One Gustave L. Levy Place<br \/><\/span><span style=\"font-size: 16px\">Annenberg<br \/><\/span><span style=\"font-size: 16px\">New York, NY 10029<\/span><\/p>\n<p>[\/et_pb_text][\/et_pb_column][\/et_pb_row][\/et_pb_section][et_pb_section fb_built=&#8221;1&#8243; disabled_on=&#8221;off|off|off&#8221; admin_label=&#8221;Footer Fullwidth &#8211; Section 13&#8243; module_class=&#8221;footer-section&#8221; _builder_version=&#8221;4.9.0&#8243; background_color=&#8221;#c7eafb&#8221; background_image=&#8221;https:\/\/labs.icahn.mssm.edu\/dardiklab2\/wp-content\/uploads\/sites\/616\/2022\/10\/Rectangle-3.png&#8221; max_width=&#8221;100%&#8221; max_width_tablet=&#8221;&#8221; max_width_phone=&#8221;&#8221; max_width_last_edited=&#8221;on|phone&#8221; module_alignment=&#8221;center&#8221; custom_margin=&#8221;100px|||176px|false|false&#8221; custom_padding=&#8221;3px|0px|0px|0px|false|false&#8221; animation_style=&#8221;slide&#8221; animation_direction=&#8221;bottom&#8221; animation_intensity_slide=&#8221;14%&#8221; 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_builder_version=&#8221;4.16&#8243; custom_padding=&#8221;|||&#8221; global_colors_info=&#8221;{}&#8221; custom_padding__hover=&#8221;|||&#8221;][et_pb_text admin_label=&#8221;Text&#8221; _builder_version=&#8221;4.27.4&#8243; text_font=&#8221;||||||||&#8221; text_text_color=&#8221;#FFFFFF&#8221; text_line_height=&#8221;1.25em&#8221; header_font=&#8221;||||||||&#8221; header_4_font=&#8221;|700||on|||||&#8221; header_4_font_size=&#8221;16px&#8221; header_4_letter_spacing=&#8221;1px&#8221; header_4_line_height=&#8221;1.5em&#8221; background_layout=&#8221;dark&#8221; locked=&#8221;off&#8221; global_colors_info=&#8221;{}&#8221;]<\/p>\n<p><strong>E-mail<br \/><\/strong>alan.dardik@mountsinai.org<\/p>\n<p>&nbsp;<\/p>\n<p>[\/et_pb_text][\/et_pb_column][et_pb_column type=&#8221;1_3&#8243; _builder_version=&#8221;4.16&#8243; custom_padding=&#8221;|||&#8221; global_colors_info=&#8221;{}&#8221; custom_padding__hover=&#8221;|||&#8221;][et_pb_text _builder_version=&#8221;4.27.4&#8243; text_font=&#8221;||||||||&#8221; text_text_color=&#8221;#FFFFFF&#8221; text_line_height=&#8221;1.25em&#8221; header_font=&#8221;||||||||&#8221; header_4_font=&#8221;|700||on|||||&#8221; header_4_font_size=&#8221;16px&#8221; header_4_letter_spacing=&#8221;1px&#8221; header_4_line_height=&#8221;1.5em&#8221; background_layout=&#8221;dark&#8221; locked=&#8221;off&#8221; global_colors_info=&#8221;{}&#8221;]<\/p>\n<p><strong>Lab Address <\/strong><br \/>Icahn School of Medicine at Mount Sinai, Annenberg Building, Room 25-98, 5 E 98th St, \u00a0New York, NY 10029, United States.<\/p>\n<p><strong>Mailing Address <\/strong><\/p>\n<p>Icahn School of Medicine at Mount Sinai, \u00a05 E 98th St, Box 1259, New York, NY 10029, United States.<\/p>\n<p>[\/et_pb_text][\/et_pb_column][\/et_pb_row][\/et_pb_section]<\/p>\n","protected":false},"excerpt":{"rendered":"<p>PublicationsOur current research focuses on the mechnism of arteriovenous fistula failureAoyagi Y, Schwartz AW, Li Z, Bai H, Ho B, Lazcano-Etchebarne C, Gonzalez L, Ohashi Y, Kano M, Yatsula B, Ochoa Chaar CI, Martin K, Vazquez-Padron R, Dai G, Dardik A. Sox17 mediates venous adaptive remodeling after arteriovenous fistula creation. JVS Vasc Sci. 2025 Aug [&hellip;]<\/p>\n","protected":false},"author":545,"featured_media":0,"parent":0,"menu_order":4,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_et_pb_use_builder":"on","_et_pb_old_content":"","_et_gb_content_width":"","inline_featured_image":false,"footnotes":""},"class_list":["post-2494","page","type-page","status-publish","hentry"],"aioseo_notices":[],"_links":{"self":[{"href":"https:\/\/labs.icahn.mssm.edu\/dardiklab\/wp-json\/wp\/v2\/pages\/2494","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/labs.icahn.mssm.edu\/dardiklab\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/labs.icahn.mssm.edu\/dardiklab\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/labs.icahn.mssm.edu\/dardiklab\/wp-json\/wp\/v2\/users\/545"}],"replies":[{"embeddable":true,"href":"https:\/\/labs.icahn.mssm.edu\/dardiklab\/wp-json\/wp\/v2\/comments?post=2494"}],"version-history":[{"count":10,"href":"https:\/\/labs.icahn.mssm.edu\/dardiklab\/wp-json\/wp\/v2\/pages\/2494\/revisions"}],"predecessor-version":[{"id":4711,"href":"https:\/\/labs.icahn.mssm.edu\/dardiklab\/wp-json\/wp\/v2\/pages\/2494\/revisions\/4711"}],"wp:attachment":[{"href":"https:\/\/labs.icahn.mssm.edu\/dardiklab\/wp-json\/wp\/v2\/media?parent=2494"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}