{"id":1374,"date":"2021-02-20T20:29:43","date_gmt":"2021-02-20T20:29:43","guid":{"rendered":"https:\/\/labs.icahn.mssm.edu\/cholab\/?p=1374"},"modified":"2023-06-20T13:32:22","modified_gmt":"2023-06-20T13:32:22","slug":"september-2019-in-collaboration-with-miriam-merad-and-effi-kenigsberg-we-identified-a-new-cellular-module-that-is-associated-with-resistance-to-anti-tnf-therapy-for-crohns-disease","status":"publish","type":"post","link":"https:\/\/labs.icahn.mssm.edu\/cholab\/september-2019-in-collaboration-with-miriam-merad-and-effi-kenigsberg-we-identified-a-new-cellular-module-that-is-associated-with-resistance-to-anti-tnf-therapy-for-crohns-disease\/","title":{"rendered":"September 2019 \u2013 In collaboration with Miriam Merad and Effi Kenigsberg, we identified a new cellular module that is associated with resistance to anti-TNF therapy for Crohn\u2019s disease using single cell analysis of the terminal ileum involved in active disease."},"content":{"rendered":"<p><a title=\"\" href=\"https:\/\/labs.icahn.mssm.edu\/cholab\/wp-content\/uploads\/sites\/2\/2019\/11\/1-s2.0-S0092867419308967-fx1.jpg\"><img loading=\"lazy\" decoding=\"async\" class=\" wp-image-1328 aligncenter\" src=\"https:\/\/labs.icahn.mssm.edu\/cholab\/wp-content\/uploads\/sites\/2\/2019\/11\/1-s2.0-S0092867419308967-fx1-300x300.jpg\" alt=\"\" width=\"189\" height=\"189\" srcset=\"https:\/\/labs.icahn.mssm.edu\/cholab\/wp-content\/uploads\/sites\/2\/2019\/11\/1-s2.0-S0092867419308967-fx1-300x300.jpg 300w, https:\/\/labs.icahn.mssm.edu\/cholab\/wp-content\/uploads\/sites\/2\/2019\/11\/1-s2.0-S0092867419308967-fx1-150x150.jpg 150w, https:\/\/labs.icahn.mssm.edu\/cholab\/wp-content\/uploads\/sites\/2\/2019\/11\/1-s2.0-S0092867419308967-fx1.jpg 375w\" sizes=\"auto, (max-width: 189px) 100vw, 189px\" \/><\/a><\/p>\n<p><small>Martin, J. C., Chang, C., Boschetti, G., Ungaro, R., Giri, M., Grout, J. A., \u2026 &amp; Dubinsky, M. (2019). Single-Cell Analysis of Crohn\u2019s Disease Lesions Identifies a Pathogenic Cellular Module Associated with Resistance to Anti-TNF Therapy.\u00a0<i>Cell<\/i>,\u00a0<i>178<\/i>(6), 1493-1508.<\/small><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Martin, J. C., Chang, C., Boschetti, G., Ungaro, R., Giri, M., Grout, J. A., \u2026 &amp; Dubinsky, M. (2019). Single-Cell Analysis of Crohn\u2019s Disease Lesions Identifies a Pathogenic Cellular Module Associated with Resistance to Anti-TNF Therapy.\u00a0Cell,\u00a0178(6), 1493-1508.<\/p>\n","protected":false},"author":4,"featured_media":0,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[1],"tags":[],"class_list":["post-1374","post","type-post","status-publish","format-standard","hentry","category-uncategorized"],"aioseo_notices":[],"_links":{"self":[{"href":"https:\/\/labs.icahn.mssm.edu\/cholab\/wp-json\/wp\/v2\/posts\/1374","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/labs.icahn.mssm.edu\/cholab\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/labs.icahn.mssm.edu\/cholab\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/labs.icahn.mssm.edu\/cholab\/wp-json\/wp\/v2\/users\/4"}],"replies":[{"embeddable":true,"href":"https:\/\/labs.icahn.mssm.edu\/cholab\/wp-json\/wp\/v2\/comments?post=1374"}],"version-history":[{"count":1,"href":"https:\/\/labs.icahn.mssm.edu\/cholab\/wp-json\/wp\/v2\/posts\/1374\/revisions"}],"predecessor-version":[{"id":1375,"href":"https:\/\/labs.icahn.mssm.edu\/cholab\/wp-json\/wp\/v2\/posts\/1374\/revisions\/1375"}],"wp:attachment":[{"href":"https:\/\/labs.icahn.mssm.edu\/cholab\/wp-json\/wp\/v2\/media?parent=1374"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/labs.icahn.mssm.edu\/cholab\/wp-json\/wp\/v2\/categories?post=1374"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/labs.icahn.mssm.edu\/cholab\/wp-json\/wp\/v2\/tags?post=1374"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}