{"id":2,"date":"2015-11-05T19:40:01","date_gmt":"2015-11-05T19:40:01","guid":{"rendered":"http:\/\/labs.icahn.mssm.edu\/chehadelab\/?page_id=2"},"modified":"2025-02-18T17:43:31","modified_gmt":"2025-02-18T22:43:31","slug":"msced","status":"publish","type":"page","link":"https:\/\/labs.icahn.mssm.edu\/chehadelab\/msced\/","title":{"rendered":"Home"},"content":{"rendered":"

Mount Sinai Center for Eosinophilic Disorders (MSCED)<\/strong><\/span><\/span><\/h2>\n

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About Us<\/span><\/b><\/h4>\n

The Mount Sinai Center for Eosinophilic Disorders (MSCED) is a comprehensive center that focuses on the diagnosis, treatment, and research of eosinophilic gastrointestinal disorders (EGIDs), including eosinophilic esophagitis (EoE), eosinophilic gastritis (EG), eosinophilic enteritis (EoN), and eosinophilic colitis (EoC). EGIDs are chronic inflammatory diseases of various parts of the gut, where one type of white blood cell, eosinophil, infiltrates the inner lining along with other immune cells, causing symptoms. EGIDs affect both children and adults.<\/span>\u00a0<\/span><\/p>\n

Symptoms of EoE include difficulty swallowing foods and a history of food getting stuck in the esophagus, but at times can be non-specific such as stomach pain, gastroesophageal reflux symptoms, and vomiting, especially in children, leading to a misdiagnosis of acid-induced gastroesophageal reflux disease.\u00a0<\/span>\u00a0<\/span><\/p>\n

Patients with EGIDs below the esophagus, present with symptoms related to the organ affected. Examples include stomach pain and vomiting in patients with EoG and stomach pain, vomiting and diarrhea in patients with EGE and EoN. Diarrhea and blood in the stools can also occur in EoC. Since these symptoms can occur in other gastrointestinal diseases, patients with EGIDs are at times misdiagnosed as having other gastrointestinal diseases as well, such as acid-induced gastritis, irritable bowel syndrome, and inflammatory bowel disease. Children with EGIDs can suffer from failure to thrive, which is fortunately reversible with proper treatment of the underlying inflammation.<\/span>\u00a0<\/span><\/p>\n

At the MSCED, we believe that patients with EGIDs have specific needs that are best treated by a team approach to management. Working closely together, our team will help the patient and family determine a diagnosis and set up a treatment plan which can include special diets, medications, and counseling. Dietary and feeding support are provided for every patient whose condition or treatment requires it. In addition, cutting-edge therapies are being provided at our center, mostly in the context of clinical research trials, for patients who do not respond to standard-of-care therapies or would like to stop these therapies because of side effects.<\/span>\u00a0<\/span>\u00a0<\/span><\/p>\n

Since EGIDs are newly recognized diseases, there is not a lot of information as to what causes them. MSCED\u2019s director, Dr. Mirna Chehade, MD, MPH, is one of the leading researchers of eosinophilic gastrointestinal disorders publishing a number of papers and spearheading a number of research projects to further understand how these diseases occur and explore novel therapies for EGIDs.<\/span>\u00a0<\/span><\/p>\n

Clinical focus of the MSCED:<\/span><\/b>\u00a0<\/span><\/h4>\n