
{"id":3010,"date":"2022-12-21T12:17:26","date_gmt":"2022-12-21T17:17:26","guid":{"rendered":"https:\/\/labs.icahn.mssm.edu\/design\/?page_id=3010"},"modified":"2026-04-09T16:13:04","modified_gmt":"2026-04-09T20:13:04","slug":"research","status":"publish","type":"page","link":"https:\/\/labs.icahn.mssm.edu\/cardozolab\/research\/","title":{"rendered":"Laboratory Research"},"content":{"rendered":"<p>[et_pb_section fb_built=&#8221;1&#8243; admin_label=&#8221;Fullwidth Header &#8211; Background Title Description &#8211; no slider &#8211; Section 1&#8243; module_class=&#8221;header-title-desciption-no-slider-section1&#8243; _builder_version=&#8221;4.16&#8243; _module_preset=&#8221;default&#8221; background_color=&#8221;rgba(0,174,239,0.09)&#8221; background_enable_color=&#8221;off&#8221; background_image=&#8221;https:\/\/labs.icahn.mssm.edu\/cardozolab2\/wp-content\/uploads\/sites\/539\/2022\/07\/ai-002-1.jpg&#8221; parallax=&#8221;on&#8221; custom_padding=&#8221;||||false|false&#8221; bottom_divider_style=&#8221;ramp2&#8243; bottom_divider_color=&#8221;#FFFFFF&#8221; bottom_divider_height=&#8221;11vw&#8221; bottom_divider_arrangement=&#8221;above_content&#8221; saved_tabs=&#8221;all&#8221; locked=&#8221;off&#8221; collapsed=&#8221;on&#8221; global_colors_info=&#8221;{}&#8221;][et_pb_row column_structure=&#8221;3_4,1_4&#8243; _builder_version=&#8221;4.16&#8243; _module_preset=&#8221;default&#8221; background_color=&#8221;RGBA(0,0,0,0)&#8221; border_color_all=&#8221;RGBA(0,0,0,0)&#8221; global_colors_info=&#8221;{}&#8221;][et_pb_column type=&#8221;3_4&#8243; _builder_version=&#8221;4.16&#8243; _module_preset=&#8221;default&#8221; custom_padding=&#8221;10%||8vw||false|false&#8221; custom_padding_tablet=&#8221;0vw||0vw||true|false&#8221; custom_padding_phone=&#8221;&#8221; custom_padding_last_edited=&#8221;on|tablet&#8221; global_colors_info=&#8221;{}&#8221;][et_pb_text admin_label=&#8221;Text &#8211; Title&#8221; _builder_version=&#8221;4.16&#8243; _module_preset=&#8221;b3e3ff14-5f5c-4608-8ecf-1885ce3da7aa&#8221; header_font=&#8221;||||||||&#8221; header_text_color=&#8221;#FFFFFF&#8221; header_font_size=&#8221;48px&#8221; header_line_height=&#8221;60px&#8221; custom_margin=&#8221;||10px||false|false&#8221; header_font_size_tablet=&#8221;40px&#8221; header_font_size_phone=&#8221;24px&#8221; header_font_size_last_edited=&#8221;on|desktop&#8221; global_colors_info=&#8221;{}&#8221;]<\/p>\n<h1><strong>Laboratory Research<\/strong><\/h1>\n<p>[\/et_pb_text][et_pb_text admin_label=&#8221;Text &#8211; Description&#8221; _builder_version=&#8221;4.16&#8243; _module_preset=&#8221;da86b6f0-f83c-4c7c-bdd8-3019777ddffe&#8221; text_font=&#8221;||||||||&#8221; text_text_color=&#8221;#FFFFFF&#8221; text_font_size=&#8221;20px&#8221; text_line_height=&#8221;32px&#8221; text_font_size_tablet=&#8221;15px&#8221; text_font_size_phone=&#8221;14px&#8221; text_font_size_last_edited=&#8221;on|desktop&#8221; global_colors_info=&#8221;{}&#8221;]<\/p>\n<p>Our current research focuses on drug development for 4 significant health concerns: spinal cord injury, traumatic brain injury, peripheral nerve injury, and pain.<\/p>\n<p>[\/et_pb_text][\/et_pb_column][et_pb_column type=&#8221;1_4&#8243; _builder_version=&#8221;4.16&#8243; _module_preset=&#8221;default&#8221; background_color=&#8221;RGBA(0,0,0,0)&#8221; global_colors_info=&#8221;{}&#8221;][\/et_pb_column][\/et_pb_row][\/et_pb_section][et_pb_section fb_built=&#8221;1&#8243; admin_label=&#8221;Section 27 &#8211; Two Column &#8211; Title Over Text Over Button Next to Image&#8221; module_class=&#8221;section27_two_column_title_over_txt_over_btn_next_to_img&#8221; _builder_version=&#8221;4.16&#8243; _module_preset=&#8221;default&#8221; background_image=&#8221;https:\/\/labs.icahn.mssm.edu\/cardozolab2\/wp-content\/uploads\/sites\/539\/2022\/12\/9-alt.png&#8221; parallax=&#8221;on&#8221; parallax_method=&#8221;off&#8221; locked=&#8221;off&#8221; collapsed=&#8221;off&#8221; global_colors_info=&#8221;{}&#8221;][et_pb_row column_structure=&#8221;1_2,1_2&#8243; _builder_version=&#8221;4.16&#8243; _module_preset=&#8221;default&#8221; global_colors_info=&#8221;{}&#8221;][et_pb_column type=&#8221;1_2&#8243; _builder_version=&#8221;4.16&#8243; _module_preset=&#8221;default&#8221; global_colors_info=&#8221;{}&#8221;][et_pb_text _builder_version=&#8221;4.27.4&#8243; _module_preset=&#8221;default&#8221; global_colors_info=&#8221;{}&#8221;]<\/p>\n<h3>Spinal cord injury (SCI)<\/h3>\n<p><span style=\"font-weight: 400\">In this line of research, we test the mechanisms of action of small molecule agents, in order to develop new lines of drugs that would be used following SCI to reduce the severity of injury.<\/span><\/p>\n<p>[\/et_pb_text][\/et_pb_column][et_pb_column type=&#8221;1_2&#8243; _builder_version=&#8221;4.16&#8243; _module_preset=&#8221;default&#8221; global_colors_info=&#8221;{}&#8221;][et_pb_text _builder_version=&#8221;4.16&#8243; _module_preset=&#8221;default&#8221; global_colors_info=&#8221;{}&#8221;]<\/p>\n<h3><span style=\"font-weight: 400\">Traumatic brain injury (TBI)<\/span><\/h3>\n<p><span style=\"font-weight: 400\">We investigate the effects of small molecule inhibitors on behavioral traits that resemble TSD in humans, with the ultimate aim of developing oral medications that treat mild TBI-induced psychiatric problems.<\/span><\/p>\n<p>[\/et_pb_text][\/et_pb_column][\/et_pb_row][et_pb_row column_structure=&#8221;1_2,1_2&#8243; _builder_version=&#8221;4.16&#8243; _module_preset=&#8221;default&#8221; global_colors_info=&#8221;{}&#8221;][et_pb_column type=&#8221;1_2&#8243; _builder_version=&#8221;4.16&#8243; _module_preset=&#8221;default&#8221; global_colors_info=&#8221;{}&#8221;][et_pb_text _builder_version=&#8221;4.16&#8243; _module_preset=&#8221;default&#8221; global_colors_info=&#8221;{}&#8221;]<\/p>\n<h3>Peripheral nerve injury (PNI)<\/h3>\n<p><span style=\"font-weight: 400\">We study the mechanisms by which specific small molecules delay degeneration of the distal nerve stump, with the goal of improving success of surgical repair of damaged peripheral nerves.<\/span><\/p>\n<p>[\/et_pb_text][\/et_pb_column][et_pb_column type=&#8221;1_2&#8243; _builder_version=&#8221;4.16&#8243; _module_preset=&#8221;default&#8221; global_colors_info=&#8221;{}&#8221;][et_pb_text _builder_version=&#8221;4.16&#8243; _module_preset=&#8221;default&#8221; global_colors_info=&#8221;{}&#8221;]<\/p>\n<h3><span style=\"font-weight: 400\">Pain<\/span><\/h3>\n<p><span style=\"font-weight: 400\">We are researching new mechanism-based small molecules, in order to develop nonaddictive pain relief medication for peripheral nerve injury.<\/span><\/p>\n<p>[\/et_pb_text][\/et_pb_column][\/et_pb_row][\/et_pb_section][et_pb_section fb_built=&#8221;1&#8243; _builder_version=&#8221;4.16&#8243; _module_preset=&#8221;default&#8221; global_colors_info=&#8221;{}&#8221;][\/et_pb_section][et_pb_section fb_built=&#8221;1&#8243; disabled_on=&#8221;on|on|on&#8221; admin_label=&#8221;Footer &#8211; Section 13&#8243; module_class=&#8221;footer-section&#8221; _builder_version=&#8221;4.9.0&#8243; background_color=&#8221;#c7eafb&#8221; background_image=&#8221;https:\/\/labs.icahn.mssm.edu\/cardozolab2\/wp-content\/uploads\/sites\/539\/2022\/10\/Rectangle-3.png&#8221; max_width=&#8221;80%&#8221; max_width_tablet=&#8221;&#8221; max_width_phone=&#8221;&#8221; max_width_last_edited=&#8221;on|phone&#8221; module_alignment=&#8221;center&#8221; custom_margin=&#8221;100px|||176px|false|false&#8221; custom_padding=&#8221;3px|0px|40px|0px||&#8221; animation_style=&#8221;slide&#8221; animation_direction=&#8221;bottom&#8221; animation_intensity_slide=&#8221;14%&#8221; animation_starting_opacity=&#8221;100%&#8221; disabled=&#8221;on&#8221; global_module=&#8221;425&#8243; saved_tabs=&#8221;all&#8221; locked=&#8221;off&#8221; collapsed=&#8221;on&#8221; global_colors_info=&#8221;{}&#8221;][et_pb_row column_structure=&#8221;1_3,1_3,1_3&#8243; _builder_version=&#8221;4.16&#8243; background_color=&#8221;RGBA(0,0,0,0)&#8221; background_color_gradient_direction=&#8221;38deg&#8221; module_alignment=&#8221;center&#8221; custom_margin=&#8221;|auto|-2px|auto||&#8221; custom_padding=&#8221;0px|||||&#8221; locked=&#8221;off&#8221; global_colors_info=&#8221;{}&#8221;][et_pb_column type=&#8221;1_3&#8243; _builder_version=&#8221;4.16&#8243; custom_padding=&#8221;|||&#8221; global_colors_info=&#8221;{}&#8221; custom_padding__hover=&#8221;|||&#8221;][et_pb_text _builder_version=&#8221;4.16&#8243; _module_preset=&#8221;default&#8221; text_font=&#8221;||||||||&#8221; text_text_color=&#8221;#FFFFFF&#8221; text_line_height=&#8221;22px&#8221; global_colors_info=&#8221;{}&#8221;]<\/p>\n<p><span style=\"color: #ffffff\"><a style=\"color: #ffffff\" href=\"https:\/\/labs.icahn.mssm.edu\/design\">Contact Us<br \/><\/a><\/span><a href=\"https:\/\/labs.icahn.mssm.edu\/design\" style=\"font-size: 16px;color: #ffffff\">Recent News<br \/><\/a><a href=\"https:\/\/labs.icahn.mssm.edu\/design\" style=\"font-size: 16px;color: #ffffff\">Alumni<br \/><\/a><a href=\"https:\/\/labs.icahn.mssm.edu\/design\" style=\"font-size: 16px;color: #ffffff\">Researchers<br \/><\/a><a href=\"https:\/\/labs.icahn.mssm.edu\/design\" style=\"font-size: 16px;color: #ffffff\">Gallery<br \/><\/a><a href=\"https:\/\/labs.icahn.mssm.edu\/design\" style=\"font-size: 16px;color: #ffffff\">Resources<br \/><\/a><a href=\"https:\/\/labs.icahn.mssm.edu\/design\" style=\"font-size: 16px;color: #ffffff\">Submit Inquiry<br \/><\/a><a href=\"https:\/\/labs.icahn.mssm.edu\/design\" style=\"font-size: 16px;color: #ffffff\">Resources<br \/><\/a><a href=\"https:\/\/labs.icahn.mssm.edu\/design\" style=\"font-size: 16px;color: #ffffff\">Lab Trials<br \/> Accessibility<\/a><span style=\"font-size: 16px\"><\/span><\/p>\n<p>[\/et_pb_text][\/et_pb_column][et_pb_column type=&#8221;1_3&#8243; _builder_version=&#8221;4.16&#8243; custom_padding=&#8221;|||&#8221; global_colors_info=&#8221;{}&#8221; custom_padding__hover=&#8221;|||&#8221;][et_pb_text _builder_version=&#8221;4.16&#8243; text_font=&#8221;||||||||&#8221; text_text_color=&#8221;#FFFFFF&#8221; text_line_height=&#8221;1.25em&#8221; header_font=&#8221;||||||||&#8221; header_4_font=&#8221;|700||on|||||&#8221; header_4_font_size=&#8221;16px&#8221; header_4_letter_spacing=&#8221;1px&#8221; header_4_line_height=&#8221;1.5em&#8221; background_layout=&#8221;dark&#8221; locked=&#8221;off&#8221; global_colors_info=&#8221;{}&#8221;]<\/p>\n<p><strong>E-mail<br \/><\/strong>labname@mssm.edu<\/p>\n<p><strong>Phone<br \/><\/strong>Tel: 555-555-5555<\/p>\n<p>[\/et_pb_text][\/et_pb_column][et_pb_column type=&#8221;1_3&#8243; _builder_version=&#8221;4.16&#8243; custom_padding=&#8221;|||&#8221; global_colors_info=&#8221;{}&#8221; custom_padding__hover=&#8221;|||&#8221;][et_pb_text _builder_version=&#8221;4.16&#8243; text_font=&#8221;||||||||&#8221; text_text_color=&#8221;#FFFFFF&#8221; text_line_height=&#8221;1.25em&#8221; header_font=&#8221;||||||||&#8221; header_4_font=&#8221;|700||on|||||&#8221; header_4_font_size=&#8221;16px&#8221; header_4_letter_spacing=&#8221;1px&#8221; header_4_line_height=&#8221;1.5em&#8221; background_layout=&#8221;dark&#8221; locked=&#8221;off&#8221; global_colors_info=&#8221;{}&#8221;]<\/p>\n<p><strong>Lab Address <\/strong><br \/>One Gustave L. Levy Place<br \/>Annenberg<br \/>New York, NY 10029<\/p>\n<p><strong>Mailing Address <\/strong><\/p>\n<p>Lab Name<br \/> Icahn School of Medicine <br \/>at Mount Sinai<br \/><span style=\"font-size: 16px\">One Gustave L. Levy Place<br \/><\/span><span style=\"font-size: 16px\">Annenberg<br \/><\/span><span style=\"font-size: 16px\">New York, NY 10029<\/span><\/p>\n<p>[\/et_pb_text][\/et_pb_column][\/et_pb_row][\/et_pb_section][et_pb_section fb_built=&#8221;1&#8243; disabled_on=&#8221;off|off|off&#8221; admin_label=&#8221;Footer Fullwidth &#8211; Section 13&#8243; module_class=&#8221;footer-section&#8221; _builder_version=&#8221;4.9.0&#8243; background_color=&#8221;#c7eafb&#8221; background_image=&#8221;https:\/\/labs.icahn.mssm.edu\/cardozolab2\/wp-content\/uploads\/sites\/539\/2022\/10\/Rectangle-3.png&#8221; max_width=&#8221;100%&#8221; max_width_tablet=&#8221;&#8221; max_width_phone=&#8221;&#8221; max_width_last_edited=&#8221;on|phone&#8221; module_alignment=&#8221;center&#8221; custom_margin=&#8221;100px|||176px|false|false&#8221; custom_padding=&#8221;3px|0px|0px|0px|false|false&#8221; animation_style=&#8221;slide&#8221; animation_direction=&#8221;bottom&#8221; animation_intensity_slide=&#8221;14%&#8221; animation_starting_opacity=&#8221;100%&#8221; global_module=&#8221;3741&#8243; saved_tabs=&#8221;all&#8221; locked=&#8221;off&#8221; collapsed=&#8221;on&#8221; global_colors_info=&#8221;{}&#8221;][et_pb_row _builder_version=&#8221;4.16&#8243; background_color=&#8221;RGBA(0,0,0,0)&#8221; background_color_gradient_direction=&#8221;38deg&#8221; module_alignment=&#8221;center&#8221; custom_margin=&#8221;|auto||147px||&#8221; locked=&#8221;off&#8221; collapsed=&#8221;on&#8221; global_colors_info=&#8221;{}&#8221;][et_pb_column type=&#8221;4_4&#8243; _builder_version=&#8221;4.16&#8243; custom_padding=&#8221;|||&#8221; global_colors_info=&#8221;{}&#8221; custom_padding__hover=&#8221;|||&#8221;][et_pb_text _builder_version=&#8221;4.16&#8243; _module_preset=&#8221;default&#8221; text_text_color=&#8221;#FFFFFF&#8221; text_font_size=&#8221;24px&#8221; global_colors_info=&#8221;{}&#8221;]<\/p>\n<p style=\"text-align: center\"><strong>Contact Us<\/strong><\/p>\n<p>[\/et_pb_text][\/et_pb_column][\/et_pb_row][et_pb_row column_structure=&#8221;1_3,1_3,1_3&#8243; _builder_version=&#8221;4.16&#8243; background_color=&#8221;RGBA(0,0,0,0)&#8221; background_color_gradient_direction=&#8221;38deg&#8221; module_alignment=&#8221;center&#8221; custom_margin=&#8221;|auto|-2px|auto||&#8221; custom_padding=&#8221;0px|||||&#8221; locked=&#8221;off&#8221; collapsed=&#8221;on&#8221; global_colors_info=&#8221;{}&#8221;][et_pb_column type=&#8221;1_3&#8243; _builder_version=&#8221;4.16&#8243; custom_padding=&#8221;|||&#8221; global_colors_info=&#8221;{}&#8221; custom_padding__hover=&#8221;|||&#8221;][et_pb_text _builder_version=&#8221;4.16&#8243; _module_preset=&#8221;default&#8221; text_font=&#8221;||||||||&#8221; text_text_color=&#8221;#FFFFFF&#8221; text_line_height=&#8221;22px&#8221; global_colors_info=&#8221;{}&#8221;]<\/p>\n<p><span style=\"color: #ffffff\"><a style=\"color: #ffffff\" href=\"https:\/\/labs.icahn.mssm.edu\/design\">Contact Us<br \/><\/a><\/span><a href=\"https:\/\/labs.icahn.mssm.edu\/design\" style=\"font-size: 16px;color: #ffffff\">Recent News<br \/><\/a><a href=\"https:\/\/labs.icahn.mssm.edu\/design\" style=\"font-size: 16px;color: #ffffff\">Alumni<br \/><\/a><a href=\"https:\/\/labs.icahn.mssm.edu\/design\" style=\"font-size: 16px;color: #ffffff\">Researchers<br \/><\/a><a href=\"https:\/\/labs.icahn.mssm.edu\/design\" style=\"font-size: 16px;color: #ffffff\">Gallery<br \/><\/a><a href=\"https:\/\/labs.icahn.mssm.edu\/design\" style=\"font-size: 16px;color: #ffffff\">Resources<br \/><\/a><a href=\"https:\/\/labs.icahn.mssm.edu\/design\" style=\"font-size: 16px;color: #ffffff\">Submit Inquiry<br \/><\/a><a href=\"https:\/\/labs.icahn.mssm.edu\/design\" style=\"font-size: 16px;color: #ffffff\">Resources<br \/><\/a><a href=\"https:\/\/labs.icahn.mssm.edu\/design\" style=\"font-size: 16px;color: #ffffff\">Lab Trials<br \/> Accessibility<\/a><span style=\"font-size: 16px\"><\/span><\/p>\n<p>[\/et_pb_text][\/et_pb_column][et_pb_column type=&#8221;1_3&#8243; _builder_version=&#8221;4.16&#8243; custom_padding=&#8221;|||&#8221; global_colors_info=&#8221;{}&#8221; custom_padding__hover=&#8221;|||&#8221;][et_pb_text _builder_version=&#8221;4.16&#8243; text_font=&#8221;||||||||&#8221; text_text_color=&#8221;#FFFFFF&#8221; text_line_height=&#8221;1.25em&#8221; header_font=&#8221;||||||||&#8221; header_4_font=&#8221;|700||on|||||&#8221; header_4_font_size=&#8221;16px&#8221; header_4_letter_spacing=&#8221;1px&#8221; header_4_line_height=&#8221;1.5em&#8221; background_layout=&#8221;dark&#8221; custom_padding=&#8221;||8px|||&#8221; locked=&#8221;off&#8221; global_colors_info=&#8221;{}&#8221;]<\/p>\n<p><strong>E-mail<br \/> <\/strong>christopher.cardozo@mssm.edu<\/p>\n<p><strong>Phone<br \/><\/strong><span>718-584-9000 x1828<\/span><\/p>\n<p>[\/et_pb_text][\/et_pb_column][et_pb_column type=&#8221;1_3&#8243; _builder_version=&#8221;4.16&#8243; custom_padding=&#8221;|||&#8221; global_colors_info=&#8221;{}&#8221; custom_padding__hover=&#8221;|||&#8221;][et_pb_text _builder_version=&#8221;4.16&#8243; text_font=&#8221;||||||||&#8221; text_text_color=&#8221;#FFFFFF&#8221; text_line_height=&#8221;1.25em&#8221; header_font=&#8221;||||||||&#8221; header_4_font=&#8221;|700||on|||||&#8221; header_4_font_size=&#8221;16px&#8221; header_4_letter_spacing=&#8221;1px&#8221; header_4_line_height=&#8221;1.5em&#8221; background_layout=&#8221;dark&#8221; locked=&#8221;off&#8221; global_colors_info=&#8221;{}&#8221;]<\/p>\n<p><strong>Lab Address <\/strong><br \/><span>James J. Peters VAMC<\/span><br \/><span>Rm 3F-01<\/span><br \/><span>130 W Kingsbridge Rd.<\/span><br \/><span>Bronx, NY 10468<\/span><\/p>\n<p><strong>Mailing Address <\/strong><br \/><span>James J. Peters VAMC<\/span><br \/><span>Rm 3F-01<\/span><br \/><span>130 W Kingsbridge Rd.<\/span><br \/><span>Bronx, NY 10468<\/span><\/p>\n<p>[\/et_pb_text][\/et_pb_column][\/et_pb_row][\/et_pb_section]<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Laboratory ResearchOur current research focuses on drug development for 4 significant health concerns: spinal cord injury, traumatic brain injury, peripheral nerve injury, and pain.Spinal cord injury (SCI) In this line of research, we test the mechanisms of action of small molecule agents, in order to develop new lines of drugs that would be used following [&hellip;]<\/p>\n","protected":false},"author":545,"featured_media":0,"parent":0,"menu_order":3,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_et_pb_use_builder":"on","_et_pb_old_content":"","_et_gb_content_width":"","inline_featured_image":false,"footnotes":""},"class_list":["post-3010","page","type-page","status-publish","hentry"],"aioseo_notices":[],"_links":{"self":[{"href":"https:\/\/labs.icahn.mssm.edu\/cardozolab\/wp-json\/wp\/v2\/pages\/3010","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/labs.icahn.mssm.edu\/cardozolab\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/labs.icahn.mssm.edu\/cardozolab\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/labs.icahn.mssm.edu\/cardozolab\/wp-json\/wp\/v2\/users\/545"}],"replies":[{"embeddable":true,"href":"https:\/\/labs.icahn.mssm.edu\/cardozolab\/wp-json\/wp\/v2\/comments?post=3010"}],"version-history":[{"count":10,"href":"https:\/\/labs.icahn.mssm.edu\/cardozolab\/wp-json\/wp\/v2\/pages\/3010\/revisions"}],"predecessor-version":[{"id":5043,"href":"https:\/\/labs.icahn.mssm.edu\/cardozolab\/wp-json\/wp\/v2\/pages\/3010\/revisions\/5043"}],"wp:attachment":[{"href":"https:\/\/labs.icahn.mssm.edu\/cardozolab\/wp-json\/wp\/v2\/media?parent=3010"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}