Dongming Cai, MD, Ph.D, principal investigator. Dongming Cai is an Associate Professor of Neurology at the Icahn School of Medicine at Mount Sinai in New York, and a Physician Scientist at the James J. Peters VA Medical Center in Bronx. She trained in Neuroscience with Marie Filbin, Ph.D at Hunter College of The City University of New York, and in Molecular and Cellular Neurobiology during postdoctoral research with Nobel laureate Paul Greengard, Ph.D at The Rockefeller University. Later she received Neurology Residency training with Steve Waxman, MD, Ph.D at Yale School of Medicine. By combining expertise in basic neuroscience and clinical neurology, her laboratory studies focus on translating current understanding of disease mechanisms into development of novel diagnostic and therapeutic strategies for AD, TBI and other neurological disorders.
Jianwei Hou, MD, Senior Research Associate. Jianwei joined the Cai lab in August 2018. He works on understanding miRNA regulation of ApoE function in AD, as well as the interaction between ApoE4 and other risk factors such as sex in AD development and progression.
Jiqing Cao, MD, Ph.D, Postdoctoral Fellow. Jiqing (Spring) joined the Cai lab in September 2016. He works on understanding the molecular mechanisms underlying ApoE-regulated brain lipid homeostasis in AD, and the interaction between ApoE and gender in AD.
Carlos A Toro, Ph.D, Assistant Professor (co-mentor Dr. Christopher Cardozo). Carlos works under Dr. Cai’s guidance since 2018 on the project to investigate the role of ApoE isoforms in spinal cord injury-associated neuropathology, and determining whether manipulating brain lipid homeostasis could improve functional recovery of ApoE4 carriers after SCI.
Isabel Zats, BSc, Research Assistant. Isabel joined the Cai lab in June 2021. She works on exploring the microRNA regulation in AD development and progression. She will also participate in drug development project.
Yeji Lee, Research Intern. Yeji joined the Cai lab in December 2020. She works on exploring the interaction between ApoE4 and sex in AD development and progression.