{"id":17,"date":"2014-09-26T15:16:37","date_gmt":"2014-09-26T15:16:37","guid":{"rendered":"http:\/\/labs.icahn.mssm.edu\/brodylab\/?page_id=17"},"modified":"2020-12-01T17:19:06","modified_gmt":"2020-12-01T17:19:06","slug":"publications","status":"publish","type":"page","link":"https:\/\/labs.icahn.mssm.edu\/brodylab\/publications\/","title":{"rendered":"Publications"},"content":{"rendered":"<p>Please visit our new webpage at: <a href=\"https:\/\/thebrodylab.org\">https:\/\/thebrodylab.org<\/a><\/p>\n<p>In situ vaccination for the treatment of cancer.<br \/>\nHammerich L, Bhardwaj N, Kohrt HE, Brody JD. Immunotherapy. 2016 Mar;8(3):315-30. doi: 10.2217\/imt.15.120. PMID: 26860335<\/p>\n<p>Expansion and Activation of CD103(+) Dendritic Cell Progenitors at the Tumor Site Enhances Tumor Responses to Therapeutic PD-L1 and BRAF Inhibition.<br \/>\nSalmon H, Idoyaga J, Rahman A, Leboeuf M, Remark R, Jordan S, Casanova-Acebes M, Khudoynazarova M, Agudo J, Tung N, Chakarov S, Rivera C, Hogstad B, Bosenberg M, Hashimoto D, Gnjatic S, Bhardwaj N, Palucka AK, Brown BD, Brody J, Ginhoux F, Merad M. Immunity. 2016 Apr 19;44(4):924-38. doi: 10.1016\/j.immuni.2016.03.012. PMID: 27096321<\/p>\n<p>DC-SIGN(+) Macrophages Control the Induction of Transplantation Tolerance.<br \/>\nConde P, Rodriguez M, van der Touw W, Jimenez A, Burns M, Miller J, Brahmachary M, Chen HM, Boros P, Rausell-Palamos F, Yun TJ, Riquelme P, Rastrojo A, Aguado B, Stein-Streilein J, Tanaka M, Zhou L, Zhang J, Lowary TL, Ginhoux F, Park CG, Cheong C, Brody J, Turley SJ, Lira SA, Bronte V, Gordon S, Heeger PS, Merad M, Hutchinson J, Chen SH, Ochando J. Immunity. 2015 Jun 16;42(6):1143-58. doi: 10.1016\/j.immuni.2015.05.009. PMID: 26070485<\/p>\n<p>In situ vaccination: Cancer immunotherapy both personalized and off-the-shelf.<br \/>\nHammerich L, Binder A, Brody JD. Mol Oncol. 2015 Dec;9(10):1966-81. doi: 10.1016\/j.molonc.2015.10.016. Review. PMID: 26632446<\/p>\n<p>Lymph nodes can accurately be measured on PET-CT for lymphoma staging\/restaging without a concomitant contrast enhanced CT scan.<br \/>\nSimpson WL Jr, Lee KM, Sosa N, Cooper N, Scigliano E, Brody JD, Doucette JT, Kostakoglu L. Leuk Lymphoma. 2016 May;57(5):1083-93. doi: 10.3109\/10428194.2015.1089437. Epub 2015 Nov 16. PMID: 26422408<\/p>\n<p>In-situ tumor vaccination: Bringing the fight to the tumor.<br \/>\nPierce RH, Campbell JS, Pai SI, Brody JD, Kohrt HE. Hum Vaccin Immunother. 2015;11(8):1901-9. doi: 10.1080\/21645515.2015.1049779. Review. PMID: 26055074<\/p>\n<p>Lymphoma: immune evasion strategies.<br \/>\nUpadhyay R, Hammerich L, Peng P, Brown B, Merad M, Brody JD. Cancers (Basel). 2015 Apr 30;7(2):736-62. doi: 10.3390\/cancers7020736. Review. PMID: 25941795 Free PMC Article<\/p>\n<p>Dendritic cells and lymphoma cells: come together right now.<br \/>\nBhardwaj N, Brody JD. Blood. 2015 Jan 1;125(1):5-7. doi: 10.1182\/blood-2014-11-606608. No abstract available. PMID: 25554743<\/p>\n<p>Signaling pathways in lymphoma: pathogenesis and therapeutic targets.<br \/>\nArita A, McFarland DC, Myklebust JH, Parekh S, Petersen B, Gabrilove J, Brody JD. Future Oncol. 2013 Oct;9(10):1549-71. doi: 10.2217\/fon.13.113. Review. PMID: 24106904<\/p>\n<p>\u03b2-Catenin-independent activation of TCF1\/LEF1 in human hematopoietic tumor cells through interaction with ATF2 transcription factors.<br \/>\nGrumolato L, Liu G, Haremaki T, Mungamuri SK, Mong P, Akiri G, Lopez-Bergami P, Arita A, Anouar Y, Mlodzik M, Ronai ZA, Brody J, Weinstein DC, Aaronson SA. PLoS Genet. 2013;9(8):e1003603. doi: 10.1371\/journal.pgen.1003603.<\/p>\n<p>Depleting tumor-specific Tregs at a single site eradicates disseminated tumors.<br \/>\nMarabelle A, Kohrt H, Sagiv-Barfi I, Ajami B, Axtell RC, Zhou G, Rajapaksa R, Green MR, Torchia J, Brody J, Luong R, Rosenblum MD, Steinman L, Levitsky HI,Tse V, Levy R. J Clin Invest. 2013 Jun 3;123(6):2447-63.<\/p>\n<p>High PD-1 expression and suppressed cytokine signaling distinguish T cells infiltrating follicular lymphoma tumors from peripheral T cells.<br \/>\nMyklebust JH, Irish JM, Brody J, Czerwinski DK, Houot R, Kohrt HE, Timmerman J, Said J, Green MR, Delabie J, Kolstad A, Alizadeh AA, Levy R. Blood. 2013 Feb 21;121(8):1367-76. doi: 10.1182\/blood-2012-04-421826.<\/p>\n<p>Cancer vaccines and T cell therapy.<br \/>\nRezvani K, Brody JD, Kohrt HE, Logan AC, Advani R, Czerwinski DK, Weng WK, Negrin RS, Carlton V, Faham M, Levy R, Barrett J. Biol Blood Marrow Transplant. 2013 Jan;19(1 Suppl):S97-S101. doi: 10.1016\/j.bbmt.2012.09.020. Epub 2012 Oct 3. Review. PMID: 23041602<\/p>\n<p>A vaccine directed to B cells and produced by cell-free protein synthesis generates potent antilymphoma immunity.<br \/>\nNg PP, Jia M, Patel KG, Brody JD, Swartz JR, Levy S, Levy R. Proc Natl Acad Sci U S A. 2012 Sep 4;109(36):14526-31. doi: 10.1073\/pnas.1211018109. PMID: 22875703<\/p>\n<p>In situ vaccination against mycosis fungoides by intratumoral injection of a TLR9 agonist combined with radiation: a phase 1\/2 study.<br \/>\nKim YH, Gratzinger D, Harrison C, Brody JD, Czerwinski DK, Ai WZ, Morales A, Abdulla F, Xing L, Navi D, Tibshirani RJ, Advani RH, Lingala B, Shah S, Hoppe RT, Levy R. Blood. 2012 Jan 12;119(2):355-63. doi: 10.1182\/blood-2011-05-355222. PMID: 22045986<\/p>\n<p>Idiotype vaccine strategies for treatment of follicular lymphoma.<br \/>\nMahaseth H, Brody JD, Sinha R, Shenoy PJ, Flowers CR. Future Oncol. 2011 Jan;7(1):111-22. doi: 10.2217\/fon.10.159. Review. PMID: 21174542<\/p>\n<p>A CpG-loaded tumor cell vaccine induces antitumor CD4+ T cells that are effective in adoptive therapy for large and established tumors.<br \/>\nGoldstein MJ, Varghese B, Brody JD, Rajapaksa R, Kohrt H, Czerwinski DK, Levy S, Levy R.<br \/>\nBlood. 2011 Jan 6;117(1):118-27. doi: 10.1182\/blood-2010-06-288456. PMID: 20876455<\/p>\n<p>In situ vaccination with a TLR9 agonist induces systemic lymphoma regression: a phase I\/II study.<br \/>\nBrody JD, Ai WZ, Czerwinski DK, Torchia JA, Levy M, Advani RH, Kim YH, Hoppe RT, Knox SJ, Shin LK, Wapnir I, Tibshirani RJ, Levy R. J Clin Oncol. 2010 Oct 1;28(28):4324-32. doi: 10.1200\/JCO.2010.28.9793. PMID: 20697067 Free PMC Article<\/p>\n<p>Immunotransplantation preferentially expands T-effector cells over T-regulatory cells and cures large lymphoma tumors.<br \/>\nBrody JD, Goldstein MJ, Czerwinski DK, Levy R. Blood. 2009 Jan 1;113(1):85-94. doi: 10.1182\/blood-2008-05-155457. Epub 2008 Sep 23. PMID: 18812472 Free PMC Article<\/p>\n<p>Splenic diffuse large B-cell lymphoma in a patient with type 1 Gaucher disease: Diagnostic and therapeutic challenges.<br \/>\nBrody JD, Advani R, Shin LK, Bingham DB, Rosenberg SA. Ann Hematol. 2006 Nov;85(11):817-20. Epub 2006 Aug 26. No abstract available. PMID: 16937096<\/p>\n<p>DC-based cancer vaccines: lessons from clinical trials.<br \/>\nBrody JD, Engleman EG. Cytotherapy. 2004;6(2):122-7. Review. PMID: 15203988<\/p>\n<p><a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/?term=Brody%20JD[auth]\">\u00a0<\/a><br \/>\n<a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/?term=Brody%20JD[auth]\">Click here<\/a> to view a complete list of Dr. Brody&#8217;s publications.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Please visit our new webpage at: https:\/\/thebrodylab.org In situ vaccination for the treatment of cancer. Hammerich L, Bhardwaj N, Kohrt HE, Brody JD. Immunotherapy. 2016 Mar;8(3):315-30. doi: 10.2217\/imt.15.120. PMID: 26860335 Expansion and Activation of CD103(+) Dendritic Cell Progenitors at the Tumor Site Enhances Tumor Responses to Therapeutic PD-L1 and BRAF Inhibition. Salmon H, Idoyaga J, [&hellip;]<\/p>\n","protected":false},"author":146,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"open","ping_status":"open","template":"","meta":{"_et_pb_use_builder":"","_et_pb_old_content":"","_et_gb_content_width":"","footnotes":""},"class_list":["post-17","page","type-page","status-publish","hentry"],"aioseo_notices":[],"_links":{"self":[{"href":"https:\/\/labs.icahn.mssm.edu\/brodylab\/wp-json\/wp\/v2\/pages\/17","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/labs.icahn.mssm.edu\/brodylab\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/labs.icahn.mssm.edu\/brodylab\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/labs.icahn.mssm.edu\/brodylab\/wp-json\/wp\/v2\/users\/146"}],"replies":[{"embeddable":true,"href":"https:\/\/labs.icahn.mssm.edu\/brodylab\/wp-json\/wp\/v2\/comments?post=17"}],"version-history":[{"count":3,"href":"https:\/\/labs.icahn.mssm.edu\/brodylab\/wp-json\/wp\/v2\/pages\/17\/revisions"}],"predecessor-version":[{"id":131,"href":"https:\/\/labs.icahn.mssm.edu\/brodylab\/wp-json\/wp\/v2\/pages\/17\/revisions\/131"}],"wp:attachment":[{"href":"https:\/\/labs.icahn.mssm.edu\/brodylab\/wp-json\/wp\/v2\/media?parent=17"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}