{"id":2,"date":"2019-04-19T17:28:04","date_gmt":"2019-04-19T17:28:04","guid":{"rendered":"http:\/\/labs.icahn.mssm.edu\/bravo-cordero-lab\/?page_id=2"},"modified":"2020-10-02T16:45:48","modified_gmt":"2020-10-02T16:45:48","slug":"home","status":"publish","type":"page","link":"https:\/\/labs.icahn.mssm.edu\/bravo-cordero-lab\/","title":{"rendered":""},"content":{"rendered":"<h2>Overview<\/h2>\n<div style=\"width: 646px;\" class=\"wp-video\"><!--[if lt IE 9]><script>document.createElement('video');<\/script><![endif]-->\n<video class=\"wp-video-shortcode\" id=\"video-2-1\" width=\"646\" height=\"335\" loop autoplay preload=\"metadata\" controls=\"controls\"><source type=\"video\/mp4\" src=\"https:\/\/labs.icahn.mssm.edu\/bravo-cordero-lab\/wp-content\/uploads\/sites\/299\/2020\/10\/Gif-with-space.mp4?_=1\" \/><a href=\"https:\/\/labs.icahn.mssm.edu\/bravo-cordero-lab\/wp-content\/uploads\/sites\/299\/2020\/10\/Gif-with-space.mp4\">https:\/\/labs.icahn.mssm.edu\/bravo-cordero-lab\/wp-content\/uploads\/sites\/299\/2020\/10\/Gif-with-space.mp4<\/a><\/video><\/div>\n<p>&nbsp;<\/p>\n<p style=\"text-align: justify\">The goal of the \u201cIn vivo imaging of metastasis lab\u201d is to focus on understanding how tumor cells disseminate during metastasis and how the interaction with the tumor microenvironment, in particular the extracellular matrix, determinate the fate of disseminated cancer cells. We utilize high-resolution in vivo microscopy in order to study the plastic behavior of disseminating cancer cells and their dormancy-awaken transitions <em>in vivo<\/em>. The ultimate goal of the laboratory is to design therapeutic strategies to prevent metastatic recurrence by exploiting the mechanisms that cancer cells utilize to remain dormant at metastatic organs after dissemination.<\/p>\n<p><img loading=\"lazy\" decoding=\"async\" class=\"size-large wp-image-311 aligncenter\" src=\"https:\/\/labs.icahn.mssm.edu\/bravo-cordero-lab\/wp-content\/uploads\/sites\/299\/2020\/10\/Metastatic-Cascade-2-1024x644.jpg\" alt=\"\" width=\"646\" height=\"406\" srcset=\"https:\/\/labs.icahn.mssm.edu\/bravo-cordero-lab\/wp-content\/uploads\/sites\/299\/2020\/10\/Metastatic-Cascade-2-1024x644.jpg 1024w, https:\/\/labs.icahn.mssm.edu\/bravo-cordero-lab\/wp-content\/uploads\/sites\/299\/2020\/10\/Metastatic-Cascade-2-300x189.jpg 300w, https:\/\/labs.icahn.mssm.edu\/bravo-cordero-lab\/wp-content\/uploads\/sites\/299\/2020\/10\/Metastatic-Cascade-2-768x483.jpg 768w\" sizes=\"auto, (max-width: 646px) 100vw, 646px\" \/><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Overview &nbsp; The goal of the \u201cIn vivo imaging of metastasis lab\u201d is to focus on understanding how tumor cells disseminate during metastasis and how the interaction with the tumor microenvironment, in particular the extracellular matrix, determinate the fate of disseminated cancer cells. We utilize high-resolution in vivo microscopy in order to study the plastic [&hellip;]<\/p>\n","protected":false},"author":146,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"footnotes":""},"class_list":["post-2","page","type-page","status-publish","hentry"],"aioseo_notices":[],"_links":{"self":[{"href":"https:\/\/labs.icahn.mssm.edu\/bravo-cordero-lab\/wp-json\/wp\/v2\/pages\/2","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/labs.icahn.mssm.edu\/bravo-cordero-lab\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/labs.icahn.mssm.edu\/bravo-cordero-lab\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/labs.icahn.mssm.edu\/bravo-cordero-lab\/wp-json\/wp\/v2\/users\/146"}],"replies":[{"embeddable":true,"href":"https:\/\/labs.icahn.mssm.edu\/bravo-cordero-lab\/wp-json\/wp\/v2\/comments?post=2"}],"version-history":[{"count":107,"href":"https:\/\/labs.icahn.mssm.edu\/bravo-cordero-lab\/wp-json\/wp\/v2\/pages\/2\/revisions"}],"predecessor-version":[{"id":312,"href":"https:\/\/labs.icahn.mssm.edu\/bravo-cordero-lab\/wp-json\/wp\/v2\/pages\/2\/revisions\/312"}],"wp:attachment":[{"href":"https:\/\/labs.icahn.mssm.edu\/bravo-cordero-lab\/wp-json\/wp\/v2\/media?parent=2"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}