{"id":9,"date":"2016-07-21T17:02:52","date_gmt":"2016-07-21T21:02:52","guid":{"rendered":"http:\/\/labs.icahn.mssm.edu\/bhardwajlab\/?page_id=9"},"modified":"2026-02-06T19:03:06","modified_gmt":"2026-02-07T00:03:06","slug":"publications","status":"publish","type":"page","link":"https:\/\/labs.icahn.mssm.edu\/bhardwajlab\/publications\/","title":{"rendered":"RECENT PUBLICATIONS\u00a0"},"content":{"rendered":"

Click on article title to read<\/strong><\/p>\n

For a full list of publications please click here<\/a><\/strong><\/span><\/h1>\n

2026<\/strong><\/span><\/h2>\n

Onkar S, Bozkus CC, Saxena M, Bhardwaj N.<\/strong> Pipe dream to pipeline: Journey of cancer vaccines and the road ahead<\/a><\/strong>.<\/em> Nat Rev Cancer (2026). PMID: 41576943<\/span><\/span> . doi: 10.1016\/j.xcrm.2025.102575<\/p>\n

2025<\/strong><\/span><\/h2>\n

Nair SS, Chakravarty D, Balan S, Hakansson A, Duval M, Davicioni E, Liu Y, Bhardwaj S, Thin TH, Garcia-Barros M, Haines K, Al Shaarani M, Weil R, Meseck M, Ratnani P, Fatterpekar M, Gonzalez-Gugel E, Farkas A,<\/strong> Wagaskar V, Jambor I, Schlussel K, Pasat-Karasik C, Bhatt K, Dovey Z, Pedraza A, Gupta A, Lundon D, Peros A, Parekh S, Davenport L, Zhang X, Gupta R, Robison M, Knauer C, Ellis E, Rykunov D, Reva B, Padanilam B, Galsky MD, Brody R, Menon M, Salazar AM, Bhardwaj N,<\/strong> Tewari AK.<\/strong> Prostate cancer in situ autovaccination with the intratumoral viral mimic poly-ICLC: Modulating the cold tumor microenvironment<\/strong><\/a>.<\/em> Med 6, 100879 (2025). PMID: 41173002. doi: 10.1016\/j.medj.2025.100879. Epub 2025 Oct 30<\/p>\n

Mestrallet G, Ward RW, Brown M, <\/strong>Boumelha J, Rentzeperis F, Vaninov N, Saffern M, Olumuyide E, Suri P, Balan S, Velazquez L, Ananthanarayanan A, <\/strong>Chen Z, Lucas AL, Merad M, Bozkus CC, Vabret N, <\/strong>Samstein RM, Bhardwaj N.<\/strong> Targeting neoantigens conserved across organs and species overcomes tumor immune escape.<\/strong><\/a> bioRxiv (2025). doi:10.1101\/2025.09.25.678519. PMID: 41256707<\/p>\n

Balan S, <\/strong>O\u2019Brien L, Peros A, <\/strong>Wang X, Leal Rojas I, McClain C, Radford KJ, Bhardwaj N. Harnessing Notch signaling to enhance the generation and functionality of human conventional type 1 dendritic cells for cancer immunotherapy applications.<\/a> <\/strong>Cancer Immunol Res 13, 1328\u20131341 (2025). PMID: 40600891<\/p>\n

Cimen Bozkus C, Brown M, Velazquez L, <\/strong>Thomas M, Wilson EA, O\u2019Donnell T, Kaminska A, Ruchnewitz D, Geertz D, Bykov Y, Kodysh J, Oguntuyo KY, Roudko V, Hoyos D, Srivastava KD, Kleiner G, Alshammary H, Karekar N, McClain C, Gopal R, <\/strong>Nie K, Del Valle D, Delbeau-Zagelbaum D, Rodriguez D, Setal J; Mount Sinai COVID-19 Biobank Team; Carroll E, Wiesendanger M, Gulko PS, Charney A, Merad M, Kim-Schulze S, Lee B, Wajnberg A, Simon V, Greenbaum BD, Chowell D, Vabret N, Luksza M, Bhardwaj N.<\/strong> T cell epitope mapping reveals immunodominance of evolutionarily conserved regions within the SARS-CoV-2 proteome<\/strong><\/a>.<\/em> iScience<\/strong> 28<\/strong>, 113044 (2025). PMID: 40746995<\/p>\n

Shi Q, Simon EP, Cimen Bozkus C, Kaminska A, Velazquez L, Saxena M, <\/strong>Zhang Z, Belk JA, Wang S, Yang N, Zhang Y, Kwong A, Che Y, Stickels RR, Crain CR, Schmidt-Hong L, Lichti CF, Gaiha GD, Roth TL, Bhardwaj N, <\/strong>Satpathy AT, Yu B, Chang HY. Massively parallel immunopeptidome by DNA sequencing provides insights into cancer antigen presentation<\/a>.<\/strong> Nat Genet<\/strong> 57<\/strong>, 2062\u20132073 (2025). PMID: 40721532<\/p>\n

Saxena M, Anker JF, <\/strong>Kodysh J, O\u2019Donnell T, Kaminska AM, <\/strong>Meseck M, <\/strong>Hapanowicz O, Niglio SA, Salazar AM, Shah HR, Kinoshita Y, Brody R, Rubinsteyn A, Sebra RP, Bhardwaj N, <\/strong>Galsky MD. Atezolizumab plus personalized neoantigen vaccination in urothelial cancer: a phase 1 trial.<\/a><\/strong>Nat Cancer 6, 988\u2013999 (2025). PMID: 40346292<\/p>\n

Saxena M, <\/strong>Marron TU, Kodysh J, Finnigan JP Jr, Onkar S, Kaminska A, <\/strong>Tuballes K, Guo R, Sabado RL, Meseck M, O\u2019Donnell TJ, <\/strong>Sebra RP, Parekh S, Galsky MD, Blasquez A, <\/strong>Gimenez G, Bicak M, Cimen Bozkus C, <\/strong>Delbeau-Zagelbaum D, Rodriguez D, Acuna-Villaorduna A, Misiukiewicz KJ, Posner MR, Miles BA, Irie HY, Tiersten A, Doroshow DB, Wolf A, Mandeli J, Brody R, Salazar AM, Gnjatic S, Hammerbacher J, Schadt E, Friedlander P, Rubinsteyn A, Bhardwaj N. PGV001, a multi-peptide personalized neoantigen vaccine platform: Phase I study in patients with solid and hematologic malignancies in the adjuvant setting.<\/a> <\/strong>Cancer Discov 15, 930\u2013947 (2025). PMID: 40094414<\/p>\n

Galsky MD, Autio KA, Cabanski CR, Wentzel K, Graff JN, Friedlander TW, Howes TR, Shotts KM, Densmore J, Spasic M, Da Silva DM, Chen RO, Lata J, Skolnik J, Keler T, Yellin MJ, LaVallee TM, Fairchild J, Boffo S, O\u2019Donnell-Tormey J, Dugan U, Bhardwaj N, <\/strong>Subudhi SK, Fong L. Clinical and translational results from PORTER, a multicohort phase I platform trial of combination immunotherapy in metastatic castration-resistant prostate cancer.<\/em><\/a><\/strong>Clin Cancer Res 31, 1463\u20131475 (2025). PMID: 39964352<\/p>\n

Withers HG, Matsuzaki J, Long M, Rosario SR, Chodon T, Tsuji T, Koya R, Yan L, Wang J, Keler T, Lele SB, Zsiros E, Lugade A, Hutson A, Blank S, Bhardwaj N, <\/strong>Shrikant P, Liu S, Odunsi K. mTOR inhibition modulates vaccine-induced immune responses to generate memory T cells in patients with solid tumors. <\/a><\/strong>J Immunother Cancer 13, e010408 (2025). PMID: 40132910<\/p>\n

Yoo SK, Fitzgerald CW, Cho BA, Fitzgerald BG, Han C, Koh ES, Pandey A, Sfreddo H, Crowley F, Korostin MR, Debnath N, Leyfman Y, Valero C, Lee M, Vos JL, Lee AS, Zhao K, Lam S, Olumuyide E, Kuo F, Wilson EA, Hamon P, Hennequin C, Saffern M, Vuong L, Hakimi AA, Brown B, Merad M, Gnjatic S, Bhardwaj N,<\/strong> Galsky MD, Schadt EE, Samstein RM, Marron TU, G\u00f6nen M, Morris LGT, Chowell D. Prediction of checkpoint inhibitor immunotherapy efficacy for cancer using routine blood tests and clinical data. <\/a><\/strong>Nat Med 31, 869\u2013880 (2025). PMID: 39762425<\/p>\n

Mestrallet G, Brown M,<\/strong> Vaninov N, Cho NW, Velazquez L, Ananthanarayanan A, <\/strong>Spitzer M, Vabret N, Bozkus CC, <\/strong>Samstein RM, Bhardwaj N. Coordinated macrophage and T cell interactions mediate response to checkpoint blockade in colorectal cancer. <\/strong>bioRxiv (2025). doi:10.1101\/2025.02.12.637954. PMID: 40027748<\/p>\n

Belabed M, Park MD, Blouin CM, Balan S, <\/strong>Moon CY, Freed G, Quijada-\u00c1lamo M, Peros A, <\/strong>Mattiuz R, Reid AM, <\/strong>Yatim N, Boumelha J, Azimi CS, LaMarche NM, Troncoso L, Amabile A, Le Berichel J, Chen ST, Wilk CM, Brown BD, Radford KJ, Ghosh S, Rothlin CV, Yvan-Charvet L, Marron TU, Puleston DJ, Wagenblast E, Bhardwaj N, <\/strong>Lamaze C, Merad M. Cholesterol mobilization regulates dendritic cell maturation and the immunogenic response to cancer.<\/strong> Nat Immunol 26, 188\u2013199 (2025). PMID: 39838105<\/p>\n

Lurain K, Ramaswami R, Ekwede I, Eulo V, Goyal G, Menon M, Odeny TA, Sharon E, Wagner MJ, Wang CJ, Bhardwaj N, <\/strong>Friedlander PA, Abdul-Hay M, Cornejo Castro EM, Labo N, Marshall VA, Miley W, Moore K, Roshan R, Whitby D, Kask AS, Kaiser J, Han E, Wright A, Yarchoan R, Fling SP, Uldrick TS.<\/strong> Cancer Immunotherapy Trials Network 12: Pembrolizumab in HIV-associated Kaposi sarcoma.<\/strong>J Clin Oncol 43, 432\u2013442 (2025). PMID: 39356983<\/p>\n

Ward RW, Ananthanarayanan A, Bhardwaj N, Vabret N.<\/strong> Generation of lipid nanoparticle mRNA vaccines and evaluation of antigen-specific CD8\u207a T-cell responses.<\/strong>Methods Mol Biol 2965, 151\u2013178 (2025). PMID: 40877502<\/p>\n

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2024<\/strong><\/span><\/h2>\n<\/div>\n<\/div>\n<\/div>\n

Finnigan JP, Newman JH,<\/strong> Patskovsky Y, Patskovska L, Ishizuka AS, Lynn GM, Seder RA, Krogsgaard M, Bhardwaj N<\/b>. Structural basis for self-discrimination by neoantigen-specific TCRs<\/a>.<\/strong>\u00a0Nat Commun<\/i>\u00a015<\/b>, 2140 (2024) PMID: 36778273<\/p>\n

Luke JJ, Davar D, Andtbacka RH, Bhardwaj N<\/b>, Brody JD, Chesney J, Coffin R, de Baere T, de Gruijl TD, Fury M, Goldmacher G, Harrington KJ, Kaufman H, Kelly CM, Khilnani AD, Liu K, Loi S, Long GV, Melero I, Middleton M, Neyns B, Pinato DJ, Sheth RA, Solomon SB, Szapary P, Marabelle A. Society for Immunotherapy of Cancer (SITC) recommendations on intratumoral immunotherapy clinical trials (IICT): from premalignant to metastatic disease.<\/a><\/strong> J Immunother Cancer. 2024 Apr 18;12(4): e008378. doi: 10.1136\/jitc-2023-008378. PMID: 38641350<\/p>\n

Iyer RF, Verweij MC, Nair SS, Morrow D, Mansouri M, Chakravarty D, Beechwood T, Meyer C, Uebelhoer L, Lauron EJ, Selseth A, John N, Thin TH, Dzedzik S, Havenar-Daughton C, Axthelm MK, Douglas J, Korman A, Bhardwaj N<\/b>, Tewari AK, Hansen S, Malouli D, Picker LJ, Fr\u00fch K. CD8+<\/sup><\/span>\u00a0T cell targeting of tumor antigens presented by HLA-E<\/a><\/strong>. Sci Adv. 2024 May 10;10(19):eadm7515. doi: 10.1126\/sciadv.adm7515. Epub 2024 May 10. PMID: 38728394<\/p>\n

Wang L, Izadmehr S, Sfakianos JP, Tran M,<\/strong> Beaumont KG, Brody R, Cordon-Cardo C, Horowitz A, Sebra R, Oh WK, Bhardwaj N<\/b>, Galsky MD, Zhu J. Single-cell transcriptomic-informed deconvolution of bulk data identifies immune checkpoint blockade resistance in urothelial cancer<\/a><\/strong>. iScience. 2024 May 7;27(6):109928. doi:10.1016\/j.isci.2024.109928. PMID: 38812546<\/p>\n

Karekar N, Reid Cahn A<\/strong>, Morla-Folch J, Saffon A, Ward RW, Ananthanarayanan A<\/strong>, Teunissen AJP, Bhardwaj N<\/b>, Vabret N. Protocol for the development of mRNA lipid nanoparticle vaccines and analysis of immunization efficiency in mice.<\/a><\/strong> STAR Protoc. 2024 Jun 21;5(2):103087. doi: 10.1016\/j.xpro.2024.103087. Epub 2024 May 23. PMID: 38795353<\/p>\n

Tran MA, Youssef D<\/strong>, Shroff S, Chowhan D, Beaumont KG, Sebra R, Mehrazin R, Wiklund P, Lin JJ, Horowitz A, Farkas AM,<\/strong> Galsky MD, Sfakianos JP, Bhardwaj N<\/b>. Urine scRNAseq reveals new insights into the bladder tumor immune microenvironment. J Exp Med. 2024 Aug 5;221(8)<\/a><\/strong>: e20240045. doi: 10.1084\/jem.20240045. Epub 2024 Jun 7. PMID: 38847806<\/span><\/p>\n

Bicak M, Cimen Bozkus C,<\/strong> Bhardwaj N<\/b>. Checkpoint therapy in cancer treatment: progress, challenges, and future directions.<\/a> <\/strong>J Clin Invest. 2024 Sep 17;134(18): e184846. doi: 10.1172\/JCI184846. PMID: 39286978<\/p>\n

Gupta R, Das CK, Nair SS, Pedraza-Bermeo AM, Zahalka AH, Kyprianou N, Bhardwaj N,<\/b> Tewari AK. From foes to friends: rethinking the role of lymph nodes in prostate cancer<\/strong>.<\/a> Nat Rev Urol. 2024 Nov;21(11):687-700. doi: 10.1038\/s41585-024-00912-9. Epub 2024 Aug 2. PMID: 39095580.<\/span><\/p>\n

Lurain K, Ramaswami R, Ekwede I, Eulo V, Goyal G, Menon M, Odeny TA, Sharon E, Wagner MJ, Wang CJ, Bhardwaj N<\/b>, Friedlander PA, Abdul-Hay M, Cornejo Castro EM, Labo N, Marshall VA, Miley W, Moore K, Roshan R, Whitby D, Kask AS, Kaiser J, Han E, Wright A, Yarchoan R, Fling SP, Uldrick TS. Cancer Immunotherapy Trials Network 12: Pembrolizumab in HIV-Associated Kaposi Sarcoma<\/strong>.<\/a> J Clin Oncol. 2024 Oct 2: JCO2400640. doi:\u00a0 10.1200\/JCO.24.00640. Epub ahead of print. PMID: 39356983<\/p>\n

Farkas AM, Youssef D, Tran MA, Balan S, Newman JH<\/strong>, Audenet F, Anastos H, Velazquez LG, Peros A, Ananthanarayanan A, <\/strong>Daza J, Gonzalez-Gugel E, Sadanala K, <\/strong>Theorell J, <\/strong>Galsky MD, Horowitz A, Sfakianos JP, Bhardwaj N.<\/strong> Natural killer cell dysfunction in human bladder cancer is caused by tissue-specific suppression of SLAMF6 signaling. <\/strong>bioRxiv (2024). doi:10.1101\/2024.04.30.591366. PMID: 38746459<\/p>\n

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FOR A LIST OF ALL PUBLICATIONS – <\/strong>CLICK HERE<\/strong><\/a><\/p>\n

————————————————————————————<\/p>\n","protected":false},"excerpt":{"rendered":"

Click on article title to read For a full list of publications please click here 2026 Onkar S, Bozkus CC, Saxena M, Bhardwaj N. Pipe dream to pipeline: Journey of cancer vaccines and the road ahead. Nat Rev Cancer (2026). PMID: 41576943 . doi: 10.1016\/j.xcrm.2025.102575 2025 Nair SS, Chakravarty D, Balan S, Hakansson A, Duval […]<\/p>\n","protected":false},"author":184,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"footnotes":""},"class_list":["post-9","page","type-page","status-publish","hentry"],"aioseo_notices":[],"_links":{"self":[{"href":"https:\/\/labs.icahn.mssm.edu\/bhardwajlab\/wp-json\/wp\/v2\/pages\/9","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/labs.icahn.mssm.edu\/bhardwajlab\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/labs.icahn.mssm.edu\/bhardwajlab\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/labs.icahn.mssm.edu\/bhardwajlab\/wp-json\/wp\/v2\/users\/184"}],"replies":[{"embeddable":true,"href":"https:\/\/labs.icahn.mssm.edu\/bhardwajlab\/wp-json\/wp\/v2\/comments?post=9"}],"version-history":[{"count":134,"href":"https:\/\/labs.icahn.mssm.edu\/bhardwajlab\/wp-json\/wp\/v2\/pages\/9\/revisions"}],"predecessor-version":[{"id":1075,"href":"https:\/\/labs.icahn.mssm.edu\/bhardwajlab\/wp-json\/wp\/v2\/pages\/9\/revisions\/1075"}],"wp:attachment":[{"href":"https:\/\/labs.icahn.mssm.edu\/bhardwajlab\/wp-json\/wp\/v2\/media?parent=9"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}