
{"id":2494,"date":"2022-12-20T11:44:55","date_gmt":"2022-12-20T16:44:55","guid":{"rendered":"https:\/\/labs.icahn.mssm.edu\/design\/?page_id=2494"},"modified":"2025-08-06T10:53:44","modified_gmt":"2025-08-06T14:53:44","slug":"publications","status":"publish","type":"page","link":"https:\/\/labs.icahn.mssm.edu\/bernsteinlab\/publications\/","title":{"rendered":"Publications"},"content":{"rendered":"<p>[et_pb_section fb_built=&#8221;1&#8243; admin_label=&#8221;Fullwidth Header &#8211; Background Title Description &#8211; no slider &#8211; Section 1 &#8221; module_class=&#8221;header-title-desciption-no-slider-section1&#8243; _builder_version=&#8221;4.9.0&#8243; _module_preset=&#8221;default&#8221; background_color=&#8221;rgba(0,174,239,0.09)&#8221; background_enable_color=&#8221;off&#8221; background_image=&#8221;https:\/\/labs.icahn.mssm.edu\/bernsteinlab2\/wp-content\/uploads\/sites\/498\/2023\/12\/Emily_Bernstein_038copy-scaled.jpg&#8221; parallax=&#8221;on&#8221; custom_padding=&#8221;||||false|false&#8221; bottom_divider_style=&#8221;ramp2&#8243; bottom_divider_color=&#8221;#FFFFFF&#8221; bottom_divider_height=&#8221;11vw&#8221; bottom_divider_arrangement=&#8221;above_content&#8221; animation_style=&#8221;fade&#8221; animation_duration=&#8221;750ms&#8221; saved_tabs=&#8221;all&#8221; locked=&#8221;off&#8221; collapsed=&#8221;on&#8221;][et_pb_row _builder_version=&#8221;4.9.0&#8243; _module_preset=&#8221;default&#8221; background_color=&#8221;RGBA(0,0,0,0)&#8221; custom_padding=&#8221;||336px|||&#8221; border_color_all=&#8221;RGBA(0,0,0,0)&#8221;][et_pb_column type=&#8221;4_4&#8243; _builder_version=&#8221;4.9.0&#8243; _module_preset=&#8221;default&#8221; custom_padding=&#8221;10%||8vw||false|false&#8221; custom_padding_tablet=&#8221;0vw||0vw||true|false&#8221; custom_padding_phone=&#8221;&#8221; custom_padding_last_edited=&#8221;on|tablet&#8221;][\/et_pb_column][\/et_pb_row][\/et_pb_section][et_pb_section fb_built=&#8221;1&#8243; disabled_on=&#8221;off|off|off&#8221; admin_label=&#8221;Section 28 &#8211; Blog Style Publications&#8221; module_class=&#8221;section28_blog_style_publications&#8221; _builder_version=&#8221;4.9.0&#8243; background_color=&#8221;#FFFFFF&#8221; background_image=&#8221;https:\/\/labs.icahn.mssm.edu\/bernsteinlab2\/wp-content\/uploads\/sites\/498\/2022\/10\/Background-1.png&#8221; parallax=&#8221;on&#8221; parallax_method=&#8221;off&#8221; custom_padding=&#8221;100px||||false|false&#8221; animation_style=&#8221;fade&#8221; animation_duration=&#8221;700ms&#8221; saved_tabs=&#8221;all&#8221; locked=&#8221;off&#8221; collapsed=&#8221;off&#8221;][et_pb_row _builder_version=&#8221;4.9.0&#8243; _module_preset=&#8221;default&#8221; animation_style=&#8221;fade&#8221; animation_duration=&#8221;700ms&#8221;][et_pb_column type=&#8221;4_4&#8243; _builder_version=&#8221;4.9.0&#8243; _module_preset=&#8221;default&#8221;][et_pb_text _builder_version=&#8221;4.9.0&#8243; _module_preset=&#8221;default&#8221; text_font_size=&#8221;30px&#8221;]<\/p>\n<p style=\"text-align: center\"><b>Selected Publications<\/b><\/p>\n<p>[\/et_pb_text][\/et_pb_column][\/et_pb_row][et_pb_row column_structure=&#8221;1_2,1_2&#8243; _builder_version=&#8221;4.9.0&#8243; _module_preset=&#8221;default&#8221;][et_pb_column type=&#8221;1_2&#8243; _builder_version=&#8221;4.9.0&#8243; _module_preset=&#8221;default&#8221;][et_pb_button button_url=&#8221;http:\/\/www.ncbi.nlm.nih.gov\/sites\/myncbi\/1L5JO14jabY5s\/bibliography\/40544037\/public\/?sort=date&amp;direction=descending&#8221; url_new_window=&#8221;on&#8221; button_text=&#8221;See complete list of publications on PubMed&#8221; button_alignment=&#8221;center&#8221; _builder_version=&#8221;4.9.0&#8243; _module_preset=&#8221;default&#8221; custom_button=&#8221;on&#8221; button_text_size=&#8221;19px&#8221; button_border_radius=&#8221;8px&#8221; button_font=&#8221;Arial|600|||||||&#8221; button_icon=&#8221;%%53%%&#8221;][\/et_pb_button][\/et_pb_column][et_pb_column type=&#8221;1_2&#8243; _builder_version=&#8221;4.9.0&#8243; _module_preset=&#8221;default&#8221;][et_pb_button button_url=&#8221;https:\/\/scholar.google.com\/citations?user=LaoHqNoAAAAJ&amp;hl=en&#8221; url_new_window=&#8221;on&#8221; button_text=&#8221;See complete list of publications on Google Scholar&#8221; button_alignment=&#8221;center&#8221; _builder_version=&#8221;4.9.0&#8243; _module_preset=&#8221;default&#8221; custom_button=&#8221;on&#8221; button_text_size=&#8221;19px&#8221; button_border_radius=&#8221;8px&#8221; button_font=&#8221;Arial|600|||||||&#8221; button_icon=&#8221;%%53%%&#8221; button_icon_placement=&#8221;left&#8221;][\/et_pb_button][\/et_pb_column][\/et_pb_row][et_pb_row column_structure=&#8221;1_3,1_3,1_3&#8243; _builder_version=&#8221;4.9.0&#8243; background_size=&#8221;initial&#8221; background_position=&#8221;top_left&#8221; background_repeat=&#8221;repeat&#8221; animation_style=&#8221;fade&#8221; animation_duration=&#8221;700ms&#8221;][et_pb_column type=&#8221;1_3&#8243; _builder_version=&#8221;3.25&#8243; custom_padding=&#8221;|||&#8221; custom_padding__hover=&#8221;|||&#8221;][et_pb_text _builder_version=&#8221;4.9.0&#8243; _module_preset=&#8221;default&#8221; text_font_size=&#8221;14px&#8221; text_line_height=&#8221;1.5em&#8221; background_color=&#8221;#FFFFFF&#8221; custom_padding=&#8221;20px|20px|20px|20px|true|true&#8221; link_option_url_new_window=&#8221;on&#8221; box_shadow_style=&#8221;preset1&#8243; box_shadow_vertical=&#8221;0px&#8221; box_shadow_blur=&#8221;40px&#8221; box_shadow_color=&#8221;rgba(0,0,0,0.14)&#8221;]<\/p>\n<p style=\"text-align: justify\"><em>Grossi E, Nguyen CB, Carcamo S, Kirigin Calla\u00fa V, Moran S, Filipescu D, Tagore S, Firestone TM, Keogh MC, Sun L, Izar B, Hasson D, Bernstein E.<br \/><\/em><\/p>\n<p class=\"heading-title\" style=\"text-align: justify\"><strong>The SWI\/SNF PBAF complex facilitates REST occupancy at repressive chromatin.<\/strong><\/p>\n<p style=\"text-align: justify\">Molecular Cell 2025; 85(9): 1714-1729.e7.<\/p>\n<p style=\"text-align: justify\"><strong><a href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S109727652500303X?via%3Dihub\" target=\"_blank\" rel=\"noopener noreferrer\">Full Article<\/a><\/strong><\/p>\n<p>[\/et_pb_text][\/et_pb_column][et_pb_column type=&#8221;1_3&#8243; _builder_version=&#8221;3.25&#8243; custom_padding=&#8221;|||&#8221; custom_padding__hover=&#8221;|||&#8221;][et_pb_text _builder_version=&#8221;4.9.0&#8243; _module_preset=&#8221;default&#8221; text_font_size=&#8221;14px&#8221; text_line_height=&#8221;1.5em&#8221; background_color=&#8221;#FFFFFF&#8221; custom_padding=&#8221;20px|20px|20px|20px|true|true&#8221; link_option_url_new_window=&#8221;on&#8221; hover_enabled=&#8221;0&#8243; box_shadow_style=&#8221;preset1&#8243; box_shadow_vertical=&#8221;0px&#8221; box_shadow_blur=&#8221;40px&#8221; box_shadow_color=&#8221;rgba(0,0,0,0.14)&#8221; sticky_enabled=&#8221;0&#8243;]<\/p>\n<p style=\"text-align: justify\"><em>Jostes S, Vardabasso C, Dong J, Carcamo S, Singh R, Phelps R, Meadows A, Grossi E, Hasson D,\u00a0Bernstein E.<br \/><\/em><\/p>\n<p class=\"heading-title\" style=\"text-align: justify\"><strong>H2A.Z chaperones coverage on E2F target genes for melanoma cell proliferation.<\/strong><\/p>\n<p style=\"text-align: justify\">Genes &amp; Development 2024; 38(7-8): 336- 353.<\/p>\n<p style=\"text-align: justify\"><strong><a href=\"https:\/\/genesdev.cshlp.org\/content\/38\/7-8\/336.long\" target=\"_blank\" rel=\"noopener noreferrer\">Full Article<\/a><\/strong><\/p>\n<p>[\/et_pb_text][\/et_pb_column][et_pb_column type=&#8221;1_3&#8243; _builder_version=&#8221;4.9.0&#8243; _module_preset=&#8221;default&#8221;][et_pb_text _builder_version=&#8221;4.9.0&#8243; _module_preset=&#8221;default&#8221; text_font_size=&#8221;14px&#8221; text_line_height=&#8221;1.5em&#8221; background_color=&#8221;#FFFFFF&#8221; custom_padding=&#8221;20px|20px|20px|20px|true|true&#8221; link_option_url_new_window=&#8221;on&#8221; box_shadow_style=&#8221;preset1&#8243; box_shadow_vertical=&#8221;0px&#8221; box_shadow_blur=&#8221;40px&#8221; box_shadow_color=&#8221;rgba(0,0,0,0.14)&#8221;]<\/p>\n<p><em><span>Filipescu D, Carcamo S, Agarwal A, Tung N, Humblin \u00c9, Goldberg MS, Vyas NS, Beaumont KG, Demircioglu D, Sridhar S, Ghiraldini FG, Capparelli C, Aplin AE, Salmon H, Sebra R, Kamphorst AO, Merad M, Hasson D,\u00a0<\/span>Bernstein E.<br \/> <\/em><\/p>\n<p class=\"heading-title\"><strong>MacroH2A restricts inflammatory gene expression in melanoma cancer-associated fibroblasts by coordinating chromatin looping.<\/strong><\/p>\n<p>Nature Cell Biology 2023; 25(9): 1332-1345.<\/p>\n<p><strong><a href=\"https:\/\/www.nature.com\/articles\/s41556-023-01208-7\" target=\"_blank\" rel=\"noopener noreferrer\">Full Article<\/a><\/strong><\/p>\n<p><strong>Highlighted in:<\/strong> Nature Cell Biology &#8216;News and Views&#8217; (2023): <a href=\"https:\/\/www.nature.com\/articles\/s41556-023-01183-z\" target=\"_blank\" rel=\"noopener noreferrer\">Read here<\/a><\/p>\n<p>[\/et_pb_text][\/et_pb_column][\/et_pb_row][et_pb_row column_structure=&#8221;1_3,1_3,1_3&#8243; _builder_version=&#8221;4.9.0&#8243; background_size=&#8221;initial&#8221; background_position=&#8221;top_left&#8221; background_repeat=&#8221;repeat&#8221; animation_style=&#8221;fade&#8221; animation_duration=&#8221;700ms&#8221;][et_pb_column type=&#8221;1_3&#8243; _builder_version=&#8221;3.25&#8243; custom_padding=&#8221;|||&#8221; custom_padding__hover=&#8221;|||&#8221;][et_pb_text _builder_version=&#8221;4.9.0&#8243; _module_preset=&#8221;default&#8221; text_font_size=&#8221;14px&#8221; text_line_height=&#8221;1.5em&#8221; background_color=&#8221;#FFFFFF&#8221; custom_padding=&#8221;20px|20px|20px|20px|true|true&#8221; link_option_url_new_window=&#8221;on&#8221; box_shadow_style=&#8221;preset1&#8243; box_shadow_vertical=&#8221;0px&#8221; box_shadow_blur=&#8221;40px&#8221; box_shadow_color=&#8221;rgba(0,0,0,0.14)&#8221;]<\/p>\n<p><em>Ghiraldini FG, Filipescu D, Bernstein E.<br \/><\/em><\/p>\n<p class=\"heading-title\"><strong>Solid tumours hijack the histone variant network.<\/strong><\/p>\n<p>Nature reviews. Cancer 2021; 21(4): 257-275.<\/p>\n<p><strong><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/33568791\/\" target=\"_blank\" rel=\"noopener noreferrer\">Full Article<\/a><\/strong><\/p>\n<p style=\"text-align: justify\">[\/et_pb_text][\/et_pb_column][et_pb_column type=&#8221;1_3&#8243; _builder_version=&#8221;3.25&#8243; custom_padding=&#8221;|||&#8221; custom_padding__hover=&#8221;|||&#8221;][et_pb_text _builder_version=&#8221;4.9.0&#8243; _module_preset=&#8221;default&#8221; text_font_size=&#8221;14px&#8221; text_line_height=&#8221;1.5em&#8221; background_color=&#8221;#FFFFFF&#8221; custom_padding=&#8221;20px|20px|20px|20px|true|true&#8221; link_option_url_new_window=&#8221;on&#8221; box_shadow_style=&#8221;preset1&#8243; box_shadow_vertical=&#8221;0px&#8221; box_shadow_blur=&#8221;40px&#8221; box_shadow_color=&#8221;rgba(0,0,0,0.14)&#8221;]<\/p>\n<p><em><span>Qadeer ZA, Valle-Garcia D, Hasson D, Sun Z, Cook A, Nguyen C, Soriano A, Ma A, Griffiths LM, Zeineldin M, Filipescu D, Jubierre L, Chowdhury A, Deevy O, Chen X, Finkelstein DB, Bahrami A, Stewart E, Federico S, Gallego S, Dekio F, Fowkes M, Meni D, Maris JM, Weiss WA, Roberts SS, Cheung NV, Jin J, Segura MF, Dyer MA,\u00a0<\/span>Bernstein E.<br \/> <\/em><\/p>\n<p class=\"heading-title\"><strong>ATRX In-Frame Fusion Neuroblastoma Is Sensitive to EZH2 Inhibition via Modulation of Neuronal Gene Signatures.<\/strong><\/p>\n<p>Cancer Cell 2019; 36(5): 512-527.<\/p>\n<p><strong><a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/31631027\" target=\"_blank\" rel=\"noopener noreferrer\">Full Article<\/a><\/strong><\/p>\n<p>[\/et_pb_text][\/et_pb_column][et_pb_column type=&#8221;1_3&#8243; _builder_version=&#8221;4.9.0&#8243; _module_preset=&#8221;default&#8221;][et_pb_text _builder_version=&#8221;4.9.0&#8243; _module_preset=&#8221;default&#8221; text_font_size=&#8221;14px&#8221; text_line_height=&#8221;1.5em&#8221; background_color=&#8221;#FFFFFF&#8221; custom_padding=&#8221;20px|20px|20px|20px|true|true&#8221; link_option_url_new_window=&#8221;on&#8221; box_shadow_style=&#8221;preset1&#8243; box_shadow_vertical=&#8221;0px&#8221; box_shadow_blur=&#8221;40px&#8221; box_shadow_color=&#8221;rgba(0,0,0,0.14)&#8221;]<\/p>\n<p><em><span><img loading=\"lazy\" decoding=\"async\" src=\"https:\/\/labs.icahn.mssm.edu\/bernsteinlab2\/wp-content\/uploads\/sites\/498\/2023\/10\/Nature-Cover-226x300.png\" width=\"131\" height=\"174\" alt=\"\" class=\"wp-image-5098 alignnone size-medium\" style=\"margin-left: auto;margin-right: auto\" srcset=\"https:\/\/labs.icahn.mssm.edu\/bernsteinlab\/wp-content\/uploads\/sites\/498\/2023\/10\/Nature-Cover-226x300.png 226w, https:\/\/labs.icahn.mssm.edu\/bernsteinlab\/wp-content\/uploads\/sites\/498\/2023\/10\/Nature-Cover.png 440w\" sizes=\"(max-width: 131px) 100vw, 131px\" \/><\/span><\/em><em><span>Sun Z, Filipescu D, Andrade J, Gaspar-Maia A, Ueberheide B, <\/span>Bernstein E.<\/em><\/p>\n<p><strong>Transcription-associated histone pruning demarcates macroH2A chromatin domains.<\/strong><\/p>\n<p>Nature Structural &amp; Molecular Biology 2018; 25(10): 958-970.<\/p>\n<p><strong><a href=\"https:\/\/www.nature.com\/articles\/s41594-018-0134-5?utm_source=feedburner&amp;utm_medium=feed&amp;utm_campaign=Feed%3A+nsmb%2Frss%2Fcurrent+%28Nature+Structural+%26+Molecular+Biology+-+Issue%29\" target=\"_blank\" rel=\"noopener noreferrer\">Full Article<\/a><\/strong><\/p>\n<p class=\"contentpasted1\" style=\"background: white;text-align: justify\"><span style=\"font-size: 9pt\"><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/33568791\/\" target=\"_blank\" rel=\"noopener noreferrer\"><span style=\"font-family: Helvetica, sans-serif;color: #333333\"><\/span><\/a><\/span><span style=\"font-family: 'Helvetica',sans-serif;color: #333333\"><\/span><\/p>\n<p>[\/et_pb_text][\/et_pb_column][\/et_pb_row][et_pb_row column_structure=&#8221;1_3,1_3,1_3&#8243; _builder_version=&#8221;4.9.0&#8243; background_size=&#8221;initial&#8221; background_position=&#8221;top_left&#8221; background_repeat=&#8221;repeat&#8221; animation_style=&#8221;fade&#8221; animation_duration=&#8221;700ms&#8221;][et_pb_column type=&#8221;1_3&#8243; _builder_version=&#8221;3.25&#8243; custom_padding=&#8221;|||&#8221; custom_padding__hover=&#8221;|||&#8221;][et_pb_text _builder_version=&#8221;4.9.0&#8243; _module_preset=&#8221;default&#8221; text_font_size=&#8221;14px&#8221; text_line_height=&#8221;1.5em&#8221; background_color=&#8221;#FFFFFF&#8221; custom_padding=&#8221;20px|20px|20px|20px|true|true&#8221; link_option_url_new_window=&#8221;on&#8221; box_shadow_style=&#8221;preset1&#8243; box_shadow_vertical=&#8221;0px&#8221; box_shadow_blur=&#8221;40px&#8221; box_shadow_color=&#8221;rgba(0,0,0,0.14)&#8221;]<\/p>\n<p><em><span><img loading=\"lazy\" decoding=\"async\" src=\"https:\/\/labs.icahn.mssm.edu\/bernsteinlab2\/wp-content\/uploads\/sites\/498\/2023\/10\/Molecular-Cell-Cover-231x300.jpg\" width=\"138\" height=\"179\" alt=\"\" class=\"wp-image-5102 aligncenter size-medium\" \/><\/span><\/em><\/p>\n<p><em><span>Fontanals-Cirera B, Hasson D, Vardabasso C, Di Micco R, Agrawal\u00a0 P,\u00a0 Chowdhury A, Gantz M, de Pablos-Aragoneses A, Morgenstern A, Wu P, Filipescu D, Valle-Garcia D, Darvishian F, Roe JS, Davies MA, Vakoc CR, Hernando E,\u00a0<\/span>Bernstein E.<br \/> <\/em><\/p>\n<p class=\"heading-title\"><strong>Harnessing BET Inhibitor Sensitivity Reveals AMIGO2 as a Melanoma Survival Gene.<\/strong><\/p>\n<p>Molecular Cell 2017; 68(4): 731-744.e9.<\/p>\n<p><strong><a href=\"http:\/\/www.sciencedirect.com\/science\/article\/pii\/S1097276517308390\" target=\"_blank\" rel=\"noopener noreferrer\">Full Article<\/a><\/strong><\/p>\n<p><em><span>\u00a0<\/span><\/em><\/p>\n<p style=\"text-align: justify\">[\/et_pb_text][\/et_pb_column][et_pb_column type=&#8221;1_3&#8243; _builder_version=&#8221;3.25&#8243; custom_padding=&#8221;|||&#8221; custom_padding__hover=&#8221;|||&#8221;][et_pb_text _builder_version=&#8221;4.9.0&#8243; _module_preset=&#8221;default&#8221; text_font_size=&#8221;14px&#8221; text_line_height=&#8221;1.5em&#8221; background_color=&#8221;#FFFFFF&#8221; custom_padding=&#8221;20px|20px|20px|20px|true|true&#8221; link_option_url_new_window=&#8221;on&#8221; box_shadow_style=&#8221;preset1&#8243; box_shadow_vertical=&#8221;0px&#8221; box_shadow_blur=&#8221;40px&#8221; box_shadow_color=&#8221;rgba(0,0,0,0.14)&#8221;]<\/p>\n<p><em><span>Chung C-Y, Sun Z, Mullokandov G, , Bosch A, Qadeer ZA, Cihan E, , Rapp Z, Parsons R, Aguirre-Ghiso JA, \u00a0Farias EF, Brown BD, Gaspar-Maia A, <\/span>Bernstein E.<br \/> <\/em><\/p>\n<p class=\"heading-title\"><strong>Cbx8 acts non-canonically with Wdr5 to promote mammary tumorigenesis.<\/strong><\/p>\n<p>Cell Reports 2016; 16(2): 472-486.<\/p>\n<p><strong><a href=\"http:\/\/dx.doi.org\/10.1016\/j.celrep.2016.06.002\" target=\"_blank\" rel=\"noopener noreferrer\">Full Article<\/a><\/strong><\/p>\n<p style=\"text-align: justify\">\n<p class=\"contentpasted1\" style=\"background: white;text-align: justify\"><span style=\"font-size: 9pt\"><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/33568791\/\" target=\"_blank\" rel=\"noopener noreferrer\"><span style=\"font-family: Helvetica, sans-serif;color: #333333\"><\/span><\/a><\/span><span style=\"font-family: 'Helvetica',sans-serif;color: #333333\"><\/span><\/p>\n<p>[\/et_pb_text][\/et_pb_column][et_pb_column type=&#8221;1_3&#8243; _builder_version=&#8221;4.9.0&#8243; _module_preset=&#8221;default&#8221;][et_pb_text _builder_version=&#8221;4.9.0&#8243; _module_preset=&#8221;default&#8221; text_font_size=&#8221;14px&#8221; text_line_height=&#8221;1.5em&#8221; background_color=&#8221;#FFFFFF&#8221; custom_padding=&#8221;20px|20px|20px|20px|true|true&#8221; link_option_url_new_window=&#8221;on&#8221; box_shadow_style=&#8221;preset1&#8243; box_shadow_vertical=&#8221;0px&#8221; box_shadow_blur=&#8221;40px&#8221; box_shadow_color=&#8221;rgba(0,0,0,0.14)&#8221;]<\/p>\n<p style=\"text-align: justify\"><strong><a href=\"http:\/\/www.sciencedirect.com\/science\/article\/pii\/S1097276517308390\" target=\"_blank\" rel=\"noopener noreferrer\"><\/a><\/strong><em style=\"font-size: 14px;text-align: left\">Valle-Garcia D, Qadeer ZA, McHugh D, Ghiraldini FG, Chowdhury AH, Hasson D, Dyer MA, Recillas-Targa F, Bernstein E.<\/em><\/p>\n<p class=\"heading-title\"><strong>ATRX binds to atypical chromatin domains at the 3\u2019 exons of ZNF genes to preserve H3K9me3 enrichment.<\/strong><\/p>\n<p>Epigenetics 2016; 11(6): 398-414.<\/p>\n<p><strong><a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC4939920\/\" target=\"_blank\" rel=\"noopener noreferrer\">Full Article<\/a><\/strong><\/p>\n<p style=\"text-align: center\"><em><span>\u00a0<\/span><\/em><\/p>\n<p>[\/et_pb_text][\/et_pb_column][\/et_pb_row][et_pb_row column_structure=&#8221;1_3,1_3,1_3&#8243; _builder_version=&#8221;4.9.0&#8243; background_size=&#8221;initial&#8221; background_position=&#8221;top_left&#8221; background_repeat=&#8221;repeat&#8221; animation_style=&#8221;fade&#8221; animation_duration=&#8221;700ms&#8221;][et_pb_column type=&#8221;1_3&#8243; _builder_version=&#8221;3.25&#8243; custom_padding=&#8221;|||&#8221; custom_padding__hover=&#8221;|||&#8221;][et_pb_text _builder_version=&#8221;4.9.0&#8243; _module_preset=&#8221;default&#8221; text_font_size=&#8221;14px&#8221; text_line_height=&#8221;1.5em&#8221; background_color=&#8221;#FFFFFF&#8221; custom_padding=&#8221;20px|20px|20px|20px|true|true&#8221; link_option_url_new_window=&#8221;on&#8221; box_shadow_style=&#8221;preset1&#8243; box_shadow_vertical=&#8221;0px&#8221; box_shadow_blur=&#8221;40px&#8221; box_shadow_color=&#8221;rgba(0,0,0,0.14)&#8221;]<\/p>\n<p><em>Vardabasso C, Gaspar-Maia A, Hasson D, P\u00fcnzeler S, Valle-Garcia D, Straub T, Keilhauer EC Strub T, Panda T, Chung C-Y, Dong J, Segura MF, Fontanals-Cirera B, Verma A, Mann M, Hernando E, Hake SB, Bernstein E.<br \/> <\/em><\/p>\n<p class=\"heading-title\"><strong>Histone variant H2A.Z.2 mediates proliferation and drug sensitivity of malignant melanoma.<\/strong><\/p>\n<p>Molecular Cell 2015; 59: 75-88.<\/p>\n<p><strong><a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC4490946\/\" target=\"_blank\" rel=\"noopener noreferrer\">Full Article<\/a><\/strong><\/p>\n<p><strong>Highlighted in:<br \/> <\/strong>Cancer Discover &#8216;Research Watch&#8217; (2015) <a href=\"https:\/\/aacrjournals.org\/cancerdiscovery\/article\/5\/8\/795\/5315\/The-Histone-Variant-H2A-Z-2-Regulates\" target=\"_blank\" rel=\"noopener noreferrer\">Read here<\/a><br \/> Nature Review Cancer (2015) <a href=\"https:\/\/www.nature.com\/articles\/nrc3996\" target=\"_blank\" rel=\"noopener noreferrer\">Read here<\/a><\/p>\n<p style=\"text-align: justify\">[\/et_pb_text][\/et_pb_column][et_pb_column type=&#8221;1_3&#8243; _builder_version=&#8221;3.25&#8243; custom_padding=&#8221;|||&#8221; custom_padding__hover=&#8221;|||&#8221;][et_pb_text _builder_version=&#8221;4.9.0&#8243; _module_preset=&#8221;default&#8221; text_font_size=&#8221;14px&#8221; text_line_height=&#8221;1.5em&#8221; background_color=&#8221;#FFFFFF&#8221; custom_padding=&#8221;20px|20px|20px|20px|true|true&#8221; link_option_url_new_window=&#8221;on&#8221; box_shadow_style=&#8221;preset1&#8243; box_shadow_vertical=&#8221;0px&#8221; box_shadow_blur=&#8221;40px&#8221; box_shadow_color=&#8221;rgba(0,0,0,0.14)&#8221;]<\/p>\n<p><em><span>Duarte LF, Young ARJ, Wang Z, Wu H-A, Panda T, Kou Y, Kapoor A, Hasson D, Mills NR, Ma\u2019ayan A, Narita M, <\/span>Bernstein E.<br \/> <\/em><\/p>\n<p class=\"heading-title\"><strong>Histone H3.3 and its proteolytically processed form drive a cellular senescence program.<span>\u00a0<\/span><\/strong><\/p>\n<p>Nature Communications 2014; 5:5210.<\/p>\n<p><strong><a href=\"https:\/\/www.nature.com\/articles\/ncomms6210\" target=\"_blank\" rel=\"noopener noreferrer\">Full Article<\/a><\/strong><\/p>\n<p><strong>Highlighted in:<\/strong> Cancer Research, Highlights from Recent Cancer Literature (2014) <a href=\"https:\/\/aacrjournals.org\/cancerres\/article\/74\/24\/7159\/599160\/Highlights-from-Recent-Cancer-Literature\" target=\"_blank\" rel=\"noopener noreferrer\">Read here<\/a><\/p>\n<p style=\"text-align: justify\">\n<p class=\"contentpasted1\" style=\"background: white;text-align: justify\"><span style=\"font-size: 9pt\"><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/33568791\/\" target=\"_blank\" rel=\"noopener noreferrer\"><span style=\"font-family: Helvetica, sans-serif;color: #333333\"><\/span><\/a><\/span><span style=\"font-family: 'Helvetica',sans-serif;color: #333333\"><\/span><\/p>\n<p>[\/et_pb_text][\/et_pb_column][et_pb_column type=&#8221;1_3&#8243; _builder_version=&#8221;4.9.0&#8243; _module_preset=&#8221;default&#8221;][et_pb_text _builder_version=&#8221;4.9.0&#8243; _module_preset=&#8221;default&#8221; text_font_size=&#8221;14px&#8221; text_line_height=&#8221;1.5em&#8221; background_color=&#8221;#FFFFFF&#8221; custom_padding=&#8221;20px|20px|20px|20px|true|true&#8221; link_option_url_new_window=&#8221;on&#8221; box_shadow_style=&#8221;preset1&#8243; box_shadow_vertical=&#8221;0px&#8221; box_shadow_blur=&#8221;40px&#8221; box_shadow_color=&#8221;rgba(0,0,0,0.14)&#8221;]<\/p>\n<p><em><span>Gaspar-Maia A, Qadeer ZA, Ratnakumar K, Hasson D, Leu NA, Leroy G, Liu S, Costanzi C, Schaniel C, Lemischka IR, Garcia BA, Pehrson JR, <\/span>Bernstein E.<br \/> <\/em><\/p>\n<p class=\"heading-title\"><strong>macroH2A histone variants act as a barrier upon reprogramming towards pluripotency.<\/strong><\/p>\n<p>Nature Communications 2013; 4: 1565.<\/p>\n<p><strong><a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC4055026\/\" target=\"_blank\" rel=\"noopener noreferrer\">Full Article<\/a><\/strong><\/p>\n<p style=\"text-align: justify\"><strong><\/strong><\/p>\n<p>[\/et_pb_text][\/et_pb_column][\/et_pb_row][et_pb_row _builder_version=&#8221;4.9.0&#8243; 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module_alignment=&#8221;center&#8221; custom_margin=&#8221;|auto|-2px|auto||&#8221; custom_padding=&#8221;0px||104px|||&#8221; locked=&#8221;off&#8221; collapsed=&#8221;on&#8221;][et_pb_column type=&#8221;1_3&#8243; _builder_version=&#8221;4.9.0&#8243; custom_padding=&#8221;|||&#8221; custom_padding__hover=&#8221;|||&#8221;][et_pb_text _builder_version=&#8221;4.9.0&#8243; _module_preset=&#8221;default&#8221; text_font=&#8221;||||||||&#8221; text_text_color=&#8221;#FFFFFF&#8221; text_line_height=&#8221;22px&#8221; background_color=&#8221;#FFFFFF&#8221;]<\/p>\n<p><span style=\"color: #141414\"><a style=\"color: #141414\" href=\"https:\/\/labs.icahn.mssm.edu\/design\"><strong>Resources<\/strong><\/a><\/span><\/p>\n<p><a href=\"https:\/\/icahn.mssm.edu\/about\/departments\/oncological-sciences?pk_vid=99d97a63a4704bc316963459161f7a93\" target=\"_blank\" rel=\"noopener noreferrer\"><span>Department of Oncological Sciences<\/span><\/a><br \/> <a href=\"https:\/\/icahn.mssm.edu\/research\/black-family-stem-cell\" target=\"_blank\" rel=\"noopener noreferrer\"><span>Black Family Stem Cell Institute<\/span><\/a><br \/> <a href=\"https:\/\/icahn.mssm.edu\/research\/tisch\" target=\"_blank\" rel=\"noopener noreferrer\"><span>Tisch Cancer Institute<\/span><\/a><br \/> <a href=\"https:\/\/icahn.mssm.edu\/about\/departments\/dermatology\" target=\"_blank\" rel=\"noopener noreferrer\">Department of Dermatology<\/a><br \/> <a href=\"https:\/\/icahn.mssm.edu\/education\/graduate\" target=\"_blank\" rel=\"noopener noreferrer\"><span>Graduate School of Biomedical Sciences<\/span><\/a><\/p>\n<p><a href=\"https:\/\/icahn.mssm.edu\/\" target=\"_blank\" rel=\"noopener noreferrer\"><img loading=\"lazy\" decoding=\"async\" src=\"https:\/\/labs.icahn.mssm.edu\/bernsteinlab2\/wp-content\/uploads\/sites\/498\/2022\/07\/MSSMLogo.png\" width=\"276\" height=\"54\" alt=\"MSSMLogo\" class=\"wp-image-315 alignnone size-full\" srcset=\"https:\/\/labs.icahn.mssm.edu\/bernsteinlab\/wp-content\/uploads\/sites\/498\/2022\/07\/MSSMLogo.png 353w, https:\/\/labs.icahn.mssm.edu\/bernsteinlab\/wp-content\/uploads\/sites\/498\/2022\/07\/MSSMLogo-300x59.png 300w\" sizes=\"(max-width: 276px) 100vw, 276px\" \/><\/a><\/p>\n<p>[\/et_pb_text][\/et_pb_column][et_pb_column type=&#8221;1_3&#8243; _builder_version=&#8221;3.25&#8243; custom_padding=&#8221;|||&#8221; custom_padding__hover=&#8221;|||&#8221;][et_pb_text _builder_version=&#8221;4.9.0&#8243; text_font=&#8221;||||||||&#8221; text_text_color=&#8221;#FFFFFF&#8221; text_line_height=&#8221;1.25em&#8221; header_font=&#8221;||||||||&#8221; header_4_font=&#8221;|700||on|||||&#8221; header_4_font_size=&#8221;16px&#8221; header_4_letter_spacing=&#8221;1px&#8221; header_4_line_height=&#8221;1.5em&#8221; background_color=&#8221;#FFFFFF&#8221; background_layout=&#8221;dark&#8221; locked=&#8221;off&#8221;]<\/p>\n<p><span style=\"color: #000000\"><strong>E-mail<br \/> <\/strong><a href=\"mailto:emily.bernstein@mssm.edu\" target=\"_blank\" rel=\"noopener noreferrer\">emily.bernstein@mssm.edu<\/a><\/span><\/p>\n<p><span style=\"color: #000000\"><strong>Phone<br \/> <\/strong>Tel: 212-824-9335<\/p>\n<p><\/span><\/p>\n<p>[\/et_pb_text][\/et_pb_column][et_pb_column type=&#8221;1_3&#8243; _builder_version=&#8221;3.25&#8243; custom_padding=&#8221;|||&#8221; custom_padding__hover=&#8221;|||&#8221;][et_pb_text _builder_version=&#8221;4.9.0&#8243; text_font=&#8221;||||||||&#8221; text_text_color=&#8221;#FFFFFF&#8221; text_line_height=&#8221;1.25em&#8221; header_font=&#8221;||||||||&#8221; header_4_font=&#8221;|700||on|||||&#8221; header_4_font_size=&#8221;16px&#8221; header_4_letter_spacing=&#8221;1px&#8221; header_4_line_height=&#8221;1.5em&#8221; background_layout=&#8221;dark&#8221; locked=&#8221;off&#8221;]<\/p>\n<p><span style=\"color: #000000\"><strong>Lab Address <\/strong><\/span><br \/><span style=\"color: #000000\"> Department of Oncological Sciences<\/span><br \/><span style=\"color: #000000\"> Icahn School of Medicine at Mount Sinai<\/span><br \/><span style=\"color: #000000\"> One Gustave L. Levy Place, Box 1044A<\/span><br \/><span style=\"color: #000000\"> New York, NY 10029<\/span><\/p>\n<p><span style=\"color: #000000\"><strong>Administrative Assistant<\/strong><\/span><br \/><span style=\"color: #000000\"> Genevieve Joseph, PhD<\/span><br \/><span style=\"color: #000000\"> Tel: 212-824-9367<\/span><br \/> <span><span style=\"color: #000000\">E-mail:<\/span> <a href=\"mailto:genevieve.joseph@mssm.edu\">genevieve.joseph@mssm.edu<\/a><\/span><\/p>\n<p>[\/et_pb_text][\/et_pb_column][\/et_pb_row][\/et_pb_section]<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Selected PublicationsGrossi E, Nguyen CB, Carcamo S, Kirigin Calla\u00fa V, Moran S, Filipescu D, Tagore S, Firestone TM, Keogh MC, Sun L, Izar B, Hasson D, Bernstein E. The SWI\/SNF PBAF complex facilitates REST occupancy at repressive chromatin. Molecular Cell 2025; 85(9): 1714-1729.e7. Full ArticleJostes S, Vardabasso C, Dong J, Carcamo S, Singh R, Phelps [&hellip;]<\/p>\n","protected":false},"author":545,"featured_media":0,"parent":0,"menu_order":4,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_et_pb_use_builder":"on","_et_pb_old_content":"","_et_gb_content_width":"","inline_featured_image":false,"footnotes":""},"class_list":["post-2494","page","type-page","status-publish","hentry"],"aioseo_notices":[],"_links":{"self":[{"href":"https:\/\/labs.icahn.mssm.edu\/bernsteinlab\/wp-json\/wp\/v2\/pages\/2494","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/labs.icahn.mssm.edu\/bernsteinlab\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/labs.icahn.mssm.edu\/bernsteinlab\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/labs.icahn.mssm.edu\/bernsteinlab\/wp-json\/wp\/v2\/users\/545"}],"replies":[{"embeddable":true,"href":"https:\/\/labs.icahn.mssm.edu\/bernsteinlab\/wp-json\/wp\/v2\/comments?post=2494"}],"version-history":[{"count":102,"href":"https:\/\/labs.icahn.mssm.edu\/bernsteinlab\/wp-json\/wp\/v2\/pages\/2494\/revisions"}],"predecessor-version":[{"id":6352,"href":"https:\/\/labs.icahn.mssm.edu\/bernsteinlab\/wp-json\/wp\/v2\/pages\/2494\/revisions\/6352"}],"wp:attachment":[{"href":"https:\/\/labs.icahn.mssm.edu\/bernsteinlab\/wp-json\/wp\/v2\/media?parent=2494"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}