[et_pb_section fb_built=”1″ admin_label=”Fullwidth Header – Background Title Description – no slider – Section 1″ module_class=”header-title-desciption-no-slider-section1″ _builder_version=”4.9.0″ _module_preset=”default” background_color=”rgba(0,174,239,0.09)” background_enable_color=”off” background_image=”https:\/\/labs.icahn.mssm.edu\/bansallab-new\/wp-content\/uploads\/sites\/564\/2022\/07\/ai-002-1.jpg” parallax=”on” custom_padding=”||||false|false” bottom_divider_style=”ramp2″ bottom_divider_color=”#FFFFFF” bottom_divider_height=”11vw” bottom_divider_arrangement=”above_content” saved_tabs=”all” locked=”off” collapsed=”on”][et_pb_row column_structure=”1_2,1_2″ _builder_version=”4.9.0″ _module_preset=”default” background_color=”RGBA(0,0,0,0)” border_color_all=”RGBA(0,0,0,0)” collapsed=”on”][et_pb_column type=”1_2″ _builder_version=”4.9.0″ _module_preset=”default” custom_padding=”10%||8vw||false|false” custom_padding_tablet=”0vw||0vw||true|false” custom_padding_phone=”” custom_padding_last_edited=”on|tablet”][et_pb_text admin_label=”Text – Title” _builder_version=”4.9.0″ _module_preset=”b3e3ff14-5f5c-4608-8ecf-1885ce3da7aa” header_font=”||||||||” header_text_color=”#FFFFFF” header_font_size=”48px” header_line_height=”60px” custom_margin=”||10px||false|false” header_font_size_tablet=”40px” header_font_size_phone=”24px” header_font_size_last_edited=”on|desktop”]<\/p>\n
[\/et_pb_text][et_pb_text disabled_on=”on|on|on” admin_label=”Text – Description” _builder_version=”4.9.0″ _module_preset=”da86b6f0-f83c-4c7c-bdd8-3019777ddffe” text_font=”||||||||” text_text_color=”#FFFFFF” text_font_size=”20px” text_line_height=”32px” text_font_size_tablet=”15px” text_font_size_phone=”14px” text_font_size_last_edited=”on|desktop” disabled=”on”]Our current research focuses on birth of the hair follicle niche, growth control and regeneration, and tissue regression and reorganization.
\n[\/et_pb_text][\/et_pb_column][et_pb_column type=”1_2″ _builder_version=”4.9.0″ _module_preset=”default” background_color=”RGBA(0,0,0,0)”][\/et_pb_column][\/et_pb_row][\/et_pb_section][et_pb_section fb_built=”1″ admin_label=”Section 27 – Two Column – Title Over Text Over Button Next to Image” module_class=”section27_two_column_title_over_txt_over_btn_next_to_img” _builder_version=”4.9.0″ _module_preset=”default” background_image=”https:\/\/labs.icahn.mssm.edu\/bansallab-new\/wp-content\/uploads\/sites\/564\/2022\/12\/9-alt.png” parallax=”on” parallax_method=”off” locked=”off” collapsed=”on”][et_pb_row column_structure=”1_2,1_2″ _builder_version=”4.9.0″ module_alignment=”center” custom_margin=”|||” custom_margin_tablet=”” custom_margin_phone=”” custom_margin_last_edited=”on|phone” custom_padding=”||150px|||” global_module=”3003″ collapsed=”on”][et_pb_column type=”1_2″ _builder_version=”3.25″ background_color_gradient_direction=”35deg” custom_padding=”|60px||” custom_padding__hover=”|||”][et_pb_text disabled_on=”on|on|on” _builder_version=”4.9.0″ text_font=”||||||||” header_font=”||||||||” header_text_align=”left” header_text_color=”#2b2b2b” header_font_size=”36px” header_line_height=”1.3em” header_2_font=”|700|||||||” header_2_text_align=”left” header_2_text_color=”#2b2b2b” header_2_font_size=”36px” header_2_line_height=”1.5em” text_orientation=”center” module_alignment=”center” custom_margin=”||10px|” disabled=”on”]<\/p>\n
[\/et_pb_text][et_pb_text _builder_version=”4.9.0″ text_font=”||||||||” text_text_color=”#141414″ text_line_height=”1.9em” header_font=”||||||||” header_2_font=”||||||||” module_alignment=”center” custom_margin=”||30px|”]<\/p>\n
The primary focus in the laboratory is to understand how HIV promotes liver inflammation and fibrosis through interactions with both activated hepatic stellate cells (HSCs) and liver macrophages (Kupffer cells). We were the first to identify the presence of CXCR4, one of the HIV co-receptors, on HSCs in vitro and in vivo (Hong F, Hepatology, 2009). Subsequently, we demonstrated that HIV and its envelope protein infects and elicits pro-inflammatory and profibrogenic effects on HSCs through interaction with CXCR4 (Tuyama A, Hepatology, 2010; Hong F, PLoS ONE, 2012). In addition, we have found that HIV robustly infects Kupffer cells and elicits a number of pro-inflammatory and pro-fibrogenic effects. In addition, we are exploring whether intrahepatic macrophages are a reservoir for HIV in patients on anti-retroviral therapies. Our work relies heavily on the use of primary human liver cells derived from both non-HIV infected and HIV-infected patients undergoing liver resection or transplant and is complemented using relevant cell lines.<\/p>\n
In addition, the lab is interested in understanding mechanisms of non-alcoholic fatty liver disease (NAFLD) in both HIV and non-HIV infected patients. Dr. Bansal is involved in a number of clinical trials and translational studies focused on anti-fibrotic therapies, new HCV therapies, and novel treatments for NAFLD.<\/p>\n
[\/et_pb_text][et_pb_button button_url=”https:\/\/labs.icahn.mssm.edu\/design\/option1-research” button_text=”Read More” disabled_on=”on|on|on” _builder_version=”4.9.0″ _module_preset=”default” custom_button=”on” button_text_color=”#FFFFFF” button_bg_color=”#00AEEF” button_border_radius=”0px” box_shadow_style=”preset1″ disabled=”on” locked=”off”][\/et_pb_button][\/et_pb_column][et_pb_column type=”1_2″ module_class=”imageallignment” _builder_version=”4.9.0″ background_color=”RGBA(0,0,0,0)” use_background_color_gradient=”on” background_color_gradient_start=”#00aeef” background_color_gradient_end=”#221f72″ background_color_gradient_direction=”115deg” custom_padding=”|||” custom_padding__hover=”|||” custom_css_main_element_last_edited=”on|desktop” custom_css_main_element_tablet=”margin-top:60px!important”][et_pb_image src=”https:\/\/labs.icahn.mssm.edu\/bansallab-new\/wp-content\/uploads\/sites\/564\/2025\/04\/Research.jpg” title_text=”Research” align=”center” _builder_version=”4.9.0″ background_color=”#221F72″ custom_margin=”-40px|40px|40px|-40px|false|false” custom_margin_tablet=”” custom_margin_phone=”-40px|40px|40px|-40px|false|false” custom_margin_last_edited=”on|phone” custom_padding=”|||” animation_style=”zoom” animation_direction=”right” animation_intensity_zoom=”6%” animation_starting_opacity=”100%” always_center_on_mobile=”off”][\/et_pb_image][\/et_pb_column][\/et_pb_row][et_pb_row column_structure=”1_2,1_2″ make_equal=”on” disabled_on=”on|on|on” _builder_version=”4.9.0″ module_alignment=”center” custom_margin=”|auto|150px|auto||” custom_padding=”0px||0px|” disabled=”on” global_module=”3004″ collapsed=”on”][et_pb_column type=”1_2″ _builder_version=”4.9.0″ background_color=”#00AEEF” use_background_color_gradient=”on” background_color_gradient_start=”#00aeef” background_color_gradient_end=”#d80b8c” background_color_gradient_direction=”33deg” background_enable_image=”off” parallax=”on” custom_padding=”|5%||5%” custom_padding__hover=”|||”][et_pb_image src=”https:\/\/labs.icahn.mssm.edu\/bansallab-new\/wp-content\/uploads\/sites\/564\/2022\/12\/Research-1-800×1129-1.jpg” title_text=”Research-1-800×1129″ align=”center” align_tablet=”center” align_phone=”” align_last_edited=”on|desktop” _builder_version=”4.9.0″ custom_margin=”-20px||-20px|” custom_padding=”|||” animation_style=”zoom” animation_direction=”left” animation_intensity_zoom=”10%” animation_starting_opacity=”100%”][\/et_pb_image][\/et_pb_column][et_pb_column type=”1_2″ _builder_version=”3.25″ custom_padding=”40px|40px|40px|40px” custom_padding__hover=”|||”][et_pb_text _builder_version=”4.9.0″ header_font=”|700|||||||” header_font_size=”36px” header_3_font=”Playfair Display|700|||||||” header_3_text_color=”#2b2b2b” header_3_font_size=”28px” header_3_line_height=”1.5em” custom_margin=”||10px|”]<\/p>\n
[\/et_pb_text][et_pb_text _builder_version=”4.9.0″ text_font=”||||||||” text_text_color=”#141414″ text_line_height=”1.9em” header_font=”||||||||” header_2_font=”||||||||” module_alignment=”center” custom_margin=”||30px|”]<\/p>\n
One of the causes contributing to poor healing of aged musculoskeletal tissues is that mature tissues have decreased stem cell numbers and activities. To overcome this hurdle, cell-based therapies have been proposed as a strategy to trigger native tissue formation and function restoration.<\/p>\n
[\/et_pb_text][et_pb_button button_url=”https:\/\/labs.icahn.mssm.edu\/design\/option1-research” button_text=”Read More” _builder_version=”4.9.0″ _module_preset=”default” custom_button=”on” button_text_color=”#FFFFFF” button_bg_color=”#00AEEF” button_border_radius=”0px” box_shadow_style=”preset1″ locked=”off”][\/et_pb_button][\/et_pb_column][\/et_pb_row][et_pb_row column_structure=”1_2,1_2″ make_equal=”on” disabled_on=”on|on|on” _builder_version=”4.9.0″ module_alignment=”center” custom_margin=”||200px|” custom_padding=”0px|0px|0px|0px” disabled=”on” global_module=”3005″ collapsed=”off”][et_pb_column type=”1_2″ _builder_version=”3.25″ background_color_gradient_direction=”35deg” custom_padding=”40px|40px|40px|40px” custom_padding__hover=”|||”][et_pb_text _builder_version=”4.9.0″ header_font=”||||||||” header_3_font=”Playfair Display|700|||||||” header_3_text_color=”#2b2b2b” header_3_font_size=”28px” header_3_line_height=”1.5em” custom_margin=”||10px|”]<\/p>\n
[\/et_pb_text][et_pb_text _builder_version=”4.9.0″ text_font=”||||||||” text_text_color=”#141414″ text_line_height=”1.9em” header_font=”||||||||” header_2_font=”||||||||” module_alignment=”center” custom_margin=”||30px|”]<\/p>\n
Tendons are mechanosensitive load-bearing tissues. Decreased loading causes defects during development and structural remodeling in adult tendons. \u00a0To further illustrate underlying principles, tendon progenitor\/stem cells have been reported to acquire chondrogenic and osteogenic features after mechanical stimulation.\u00a0<\/p>\n
[\/et_pb_text][et_pb_button button_url=”https:\/\/labs.icahn.mssm.edu\/design\/option1-research” button_text=”Read More” _builder_version=”4.9.0″ _module_preset=”default” custom_button=”on” button_text_color=”#FFFFFF” button_bg_color=”#00AEEF” button_border_radius=”0px” box_shadow_style=”preset1″ locked=”off”][\/et_pb_button][\/et_pb_column][et_pb_column type=”1_2″ _builder_version=”4.9.0″ background_color=”#00AEEF” use_background_color_gradient=”on” background_color_gradient_start=”#221f72″ background_color_gradient_end=”#d80b8c” background_color_gradient_direction=”33deg” background_enable_image=”off” parallax=”on” custom_padding=”|5%||5%” custom_padding__hover=”|||”][et_pb_image src=”https:\/\/labs.icahn.mssm.edu\/bansallab-new\/wp-content\/uploads\/sites\/564\/2022\/12\/Research-2-800×977-1.jpg” title_text=”Research-2-800×977″ align=”center” align_tablet=”center” align_phone=”” align_last_edited=”on|desktop” _builder_version=”4.9.0″ custom_margin=”-20px||-20px|” custom_padding=”|||” animation_style=”zoom” animation_direction=”right” animation_intensity_zoom=”10%” animation_starting_opacity=”100%”][\/et_pb_image][\/et_pb_column][\/et_pb_row][\/et_pb_section][et_pb_section fb_built=”1″ disabled_on=”on|on|on” admin_label=”Footer – Section 13″ module_class=”footer-section” _builder_version=”4.9.0″ background_color=”#c7eafb” background_image=”https:\/\/labs.icahn.mssm.edu\/bansallab-new\/wp-content\/uploads\/sites\/564\/2022\/10\/Rectangle-3.png” max_width=”80%” max_width_tablet=”” max_width_phone=”” max_width_last_edited=”on|phone” module_alignment=”center” custom_margin=”100px|||176px|false|false” custom_padding=”3px|0px|40px|0px||” animation_style=”slide” animation_direction=”bottom” animation_intensity_slide=”14%” animation_starting_opacity=”100%” disabled=”on” global_module=”425″ saved_tabs=”all” locked=”off” collapsed=”on”][et_pb_row _builder_version=”4.9.0″ background_color=”RGBA(0,0,0,0)” background_color_gradient_direction=”38deg” module_alignment=”center” custom_margin=”|auto||147px||” locked=”off”][et_pb_column type=”4_4″ _builder_version=”3.25″ custom_padding=”|||” custom_padding__hover=”|||”][et_pb_social_media_follow _builder_version=”4.9.0″ _module_preset=”default” background_color=”RGBA(0,0,0,0)” text_orientation=”center”][et_pb_social_media_follow_network social_network=”linkedin” url=”https:\/\/www.linkedin.com\/school\/icahnmountsinai\/%20″ use_icon_font_size=”on” icon_font_size=”24px” _builder_version=”4.9.0″ _module_preset=”default” background_color=”RGBA(0,0,0,0)” background_enable_color=”on”]linkedin[\/et_pb_social_media_follow_network][et_pb_social_media_follow_network social_network=”facebook” url=”https:\/\/www.facebook.com\/IcahnMountSinai” use_icon_font_size=”on” icon_font_size=”24px” _builder_version=”4.9.0″ _module_preset=”default” background_color=”RGBA(0,0,0,0)” background_enable_color=”on”]facebook[\/et_pb_social_media_follow_network][et_pb_social_media_follow_network social_network=”twitter” url=”https:\/\/twitter.com\/icahnmountsinai” use_icon_font_size=”on” icon_font_size=”24px” _builder_version=”4.9.0″ _module_preset=”default” background_color=”RGBA(0,0,0,0)” background_enable_color=”on”]twitter[\/et_pb_social_media_follow_network][et_pb_social_media_follow_network social_network=”youtube” url=”https:\/\/www.youtube.com\/user\/MountSinaiSchool” use_icon_font_size=”on” icon_font_size=”24px” _builder_version=”4.9.0″ _module_preset=”default” background_color=”RGBA(0,0,0,0)” background_enable_color=”on”]youtube[\/et_pb_social_media_follow_network][et_pb_social_media_follow_network social_network=”instagram” url=”https:\/\/www.instagram.com\/icahnmountsinai\/” use_icon_font_size=”on” icon_font_size=”24px” _builder_version=”4.9.0″ _module_preset=”default” background_color=”RGBA(0,0,0,0)” background_enable_color=”on”]instagram[\/et_pb_social_media_follow_network][\/et_pb_social_media_follow][et_pb_text _builder_version=”4.9.0″ _module_preset=”default” text_text_color=”#FFFFFF” text_font_size=”24px”]<\/p>\n
Contact Us<\/strong><\/p>\n [\/et_pb_text][\/et_pb_column][\/et_pb_row][et_pb_row column_structure=”1_3,1_3,1_3″ _builder_version=”4.9.0″ background_color=”RGBA(0,0,0,0)” background_color_gradient_direction=”38deg” module_alignment=”center” custom_margin=”|auto|-2px|auto||” custom_padding=”0px|||||” locked=”off”][et_pb_column type=”1_3″ _builder_version=”4.9.0″ custom_padding=”|||” custom_padding__hover=”|||”][et_pb_text _builder_version=”4.9.0″ _module_preset=”default” text_font=”||||||||” text_text_color=”#FFFFFF” text_line_height=”22px”]<\/p>\n Contact Us [\/et_pb_text][\/et_pb_column][et_pb_column type=”1_3″ _builder_version=”3.25″ custom_padding=”|||” custom_padding__hover=”|||”][et_pb_text _builder_version=”4.9.0″ text_font=”||||||||” text_text_color=”#FFFFFF” text_line_height=”1.25em” header_font=”||||||||” header_4_font=”|700||on|||||” header_4_font_size=”16px” header_4_letter_spacing=”1px” header_4_line_height=”1.5em” background_layout=”dark” locked=”off”]<\/p>\n E-mail Phone [\/et_pb_text][\/et_pb_column][et_pb_column type=”1_3″ _builder_version=”3.25″ custom_padding=”|||” custom_padding__hover=”|||”][et_pb_text _builder_version=”4.9.0″ text_font=”||||||||” text_text_color=”#FFFFFF” text_line_height=”1.25em” header_font=”||||||||” header_4_font=”|700||on|||||” header_4_font_size=”16px” header_4_letter_spacing=”1px” header_4_line_height=”1.5em” background_layout=”dark” locked=”off”]<\/p>\n Lab Address <\/strong> Mailing Address <\/strong><\/p>\n Lab Name [\/et_pb_text][\/et_pb_column][\/et_pb_row][\/et_pb_section]<\/p>\n","protected":false},"excerpt":{"rendered":" Research Our current research focuses on birth of the hair follicle niche, growth control and regeneration, and tissue regression and reorganization. Cell Therapies for Improving Tissue RegenerationThe primary focus in the laboratory is to understand how HIV promotes liver inflammation and fibrosis through interactions with both activated hepatic stellate cells (HSCs) and liver macrophages (Kupffer […]<\/p>\n","protected":false},"author":545,"featured_media":0,"parent":0,"menu_order":3,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_et_pb_use_builder":"on","_et_pb_old_content":"","_et_gb_content_width":"","inline_featured_image":false,"footnotes":""},"class_list":["post-3010","page","type-page","status-publish","hentry"],"aioseo_notices":[],"_links":{"self":[{"href":"https:\/\/labs.icahn.mssm.edu\/bansallab\/wp-json\/wp\/v2\/pages\/3010","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/labs.icahn.mssm.edu\/bansallab\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/labs.icahn.mssm.edu\/bansallab\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/labs.icahn.mssm.edu\/bansallab\/wp-json\/wp\/v2\/users\/545"}],"replies":[{"embeddable":true,"href":"https:\/\/labs.icahn.mssm.edu\/bansallab\/wp-json\/wp\/v2\/comments?post=3010"}],"version-history":[{"count":5,"href":"https:\/\/labs.icahn.mssm.edu\/bansallab\/wp-json\/wp\/v2\/pages\/3010\/revisions"}],"predecessor-version":[{"id":4669,"href":"https:\/\/labs.icahn.mssm.edu\/bansallab\/wp-json\/wp\/v2\/pages\/3010\/revisions\/4669"}],"wp:attachment":[{"href":"https:\/\/labs.icahn.mssm.edu\/bansallab\/wp-json\/wp\/v2\/media?parent=3010"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}
<\/a><\/span>Recent News
<\/a>Alumni
<\/a>Researchers
<\/a>Gallery
<\/a>Resources
<\/a>Submit Inquiry
<\/a>Resources
<\/a>Lab Trials
Accessibility<\/a><\/span><\/p>\n
<\/strong>labname@mssm.edu<\/p>\n
<\/strong>Tel: 555-555-5555<\/p>\n
One Gustave L. Levy Place
Annenberg
New York, NY 10029<\/p>\n
Icahn School of Medicine
at Mount Sinai
One Gustave L. Levy Place
<\/span>Annenberg
<\/span>New York, NY 10029<\/span><\/p>\n