[et_pb_section fb_built=”1″ _builder_version=”4.16″ _module_preset=”default” use_background_color_gradient=”on” background_color_gradient_stops=”#4c4c4c 0%|#7a7a7a 100%” background_color_gradient_start=”#4c4c4c” background_color_gradient_end=”#7a7a7a” global_colors_info=”{}”][et_pb_row _builder_version=”4.16″ _module_preset=”default” hover_enabled=”0″ global_colors_info=”{}” sticky_enabled=”0″][et_pb_column type=”4_4″ _builder_version=”4.16″ _module_preset=”default” global_colors_info=”{}”][et_pb_text _builder_version=”4.27.4″ _module_preset=”default” hover_enabled=”0″ global_colors_info=”{}” sticky_enabled=”0″]<\/p>\n
2025<\/strong><\/span><\/p>\n Bado IL <\/strong>(Corresponding). Deterministic Role of FOXF2 in Organ-Specific Macrometastasis Transition. Cancer Res<\/em>. Read more<\/a>.<\/span><\/span><\/p>\n Alam R, Reva A, Edwards DG, Lege BM, Munoz-Arcos LS, Reduzzi C, Singh S, Hao X, Wu YH, Tian Z, Natalee LM, Damle G, Demircioglu D, Wang Y, Wu L, Molteni E, Hasson D, Lim B, Gugala Z, Chipuk JE, Lang JE, Sparano JA, Cheng C, Cristofanilli M, Xiao H, Zhang XH, Bado IL <\/strong>(Corresponding). Bone-Induced HER2 Promotes Secondary Metastasis in HR+\/HER2\u2212 Breast Cancer. Cancer Discov<\/em>. Read more<\/a>.<\/span><\/span><\/p>\n Yu L, Liebenberg K, Shen Y, Liu F, Xu Z, Hao X, Wu L, Zhang W, Chan HL, Wei B, Lorenzi PL, Gao Y, Bado I<\/strong>, Becerra-Dominguez L, Rivas CH, Aguirre S, Pingel BC, Wu YH, Ding Y, Liu J, Edwards DG, Eberlin LS, Zhang XH. <\/span>Tumor-derived arachidonic acid reprograms neutrophils to promote immune suppression and therapy resistance in triple-negative breast cancer. Immunity. <\/em><\/span>Read more<\/a><\/span>.<\/span><\/em><\/p>\n 2024<\/strong><\/span><\/p>\n Darbandi M, Bado IL<\/strong>.\u00a0Tumor Microenvironment and Epigenetic Implications in Breast Cancer Progression. Advances in Experimental Medicine and Biology. Adv Exp Med Biol<\/em>. Read more<\/a>.<\/span><\/span><\/p>\n 2023<\/strong><\/span><\/p>\n Hao X, Shen Y, Chen N, Zhang W, Valverde E, Wu L, Chan HL, Xu Z, Yu L, Gao Y, Bado I<\/strong>, Michie LN, Rivas CH, Dominguez LB, Aguirre S, Pingel BC, Wu YH, Liu F, Ding Y, Edwards DG, Liu J, Alexander A, Ueno NT, Hsueh PR, Tu CY, Liu LC, Chen SH, Hung MC, Lim B, Zhang XH<\/span>. Osteoprogenitor-GMP crosstalk underpins solid tumor-induced systemic immunosuppression and persists after tumor removal. Cell Stem Cell<\/em>. Read more<\/a>.<\/span><\/span><\/p>\n 2022<\/strong><\/span><\/p>\n Zhang W, Xu Z, Ha X, He T, Li J, Shen Y, Liu K, Gao Y, Liu J, Edwards D, Muscareela AM, Wu L, Yu L, Xu L, Chen X, Wu YH, Bado IL<\/strong>, Ding Y, Aquirre S, Wang H, Gugagla Z, Satcher RL, Wong ST, Zhang XH. Bone metastasis initiation is coupled with bone remodeling through osteogenic differentation of NG2+ cells.\u00a0Cancer Discov<\/em>. Read more<\/a>.<\/span><\/p>\n Barsky L, Coehn-Erez I,\u00a0Bado I<\/strong>, Zhang XH, Vago R. Review old bone, new tricks.\u00a0Clin Exp Metastasis<\/em> 39 (5). Read more<\/a><\/span>.<\/span><\/p>\n Stires H,\u00a0Bado I<\/strong>, Brown T, Carlson M, Chan IS, Echeverria GV, Ewald AJ, Lim B, Lloyd C, Maues J, Oesterreich S, Riter RN, Shanahan K, Welm AL, Newby J. Improving the odds together: a framework for breast cancer research scientists to include patient advocates in their research.\u00a0NPJ Breast Cancer<\/em> 8 (1). Read more<\/a><\/span>.<\/span><\/p>\n Singh S, Lee N, Pedroza DA,\u00a0Bado IL<\/strong>, Hamor C, Zhang L, Aguirre S, Hu J, Shen Y, Xu Y, Gao Y, Zhao N, Chen SH, Wan YW, Liu Z, Chang JT, Hollern D, Perou CM, Zhang XHF, Rosen JM. Chemotherapy coupled to macrophage inhibition induces T-cell and B-cell infiltration and durable regression in triple-negative breast cancer.\u00a0Cancer Res<\/em> 82 (12). Read more<\/a><\/span>.<\/span><\/p>\n \u00a02021<\/strong><\/span><\/p>\n Tian Z, Wu L, Yu C, Chen Y, XU Z,\u00a0Bado I<\/strong>, Loredo A, Wang L, Wang H, Wu KL, Zhang W, Zhang XH, Xiao H. Harnessing the power of antibodies to fight bone metastasis.\u00a0Sci Adv<\/em> 7 (26). Read more<\/a><\/span>.<\/span><\/p>\n Bado IL<\/strong>, Zhang W, Hu J, Xu Z, Wang H, Sarkar P, Li L, Wan YW, Liu J, Wu W, Lo HC, Kim IS, Singh S, Janghorban M, Muscarella AM, Goldstein A, Singh P, Jeong HH, Liu C, Schiff R, Huang S, Ellis MJ, Gaber MW, Gugala Z, Liu Z, Zhang XH. The bone microenvironment increases phenotypic plasticity of ER+ breast cancer cells.\u00a0Dev Cell<\/em> 56 (8). Read more<\/a><\/span>.<\/span><\/p>\n Zhang W,\u00a0 Bado IL<\/strong>, Hu J, Wan YW, Wu L, Wang H, Gao Y, Jeong HH, Xu Z, Hao X, Lege BM, Al-Ouran R, Li L, Li J, Yu L, Singh S, Lo HC, Niu M, Liu J, Jiang W, Li Y, Wong STC, Cheng C, Liu Z, Zhang XH. The bone microenvironemtn invigorates metastatic seeds for further dissemination.\u00a0 Cell<\/em> 184 (9). Read more<\/a><\/span>.<\/span><\/p>\n 2020<\/strong><\/span><\/p>\n Bado I<\/b>, Zhang XH. Senesce to Survive: YAP-Mediated Dormancy Escapes EGFR\/MEK Inhibition.\u00a0Cancer Cell<\/em> 37 (1). Read more<\/a><\/span>.<\/span><\/p>\n Wang H, Zhang W,\u00a0Bado I<\/strong>, Zhang XH. Bone tropism in cancer metastases.\u00a0Cold Spring Harb Perspect Med<\/em> 10 (10). Read more<\/a><\/span>.<\/span><\/p>\n 2019<\/strong><\/span><\/p>\n Kim IS, Gao Y, Welte T, Wang H, Liu J, Janghorban M, Sheng Km Niu Y, Goldstein A, Zhao N,\u00a0Bado I<\/strong>, Lo HC, Nguyen T, Bu W, Jiang W, Arnold J, Gu F, He J, Jebakumar D, Walker K, Li Y , Mo Q, Westbrook TF, Toneff MJ, Zong C, Rao A, Sreekumar A, Rosen JM, Zhang XH. Immuno-subtyping of breast cancer reveals distinct myeloid cell profiles and immunotherapy resistance mechanisms.\u00a0Nat Cell Biol<\/em> 21 (9). Read more<\/a><\/span>.<\/span><\/p>\n Gao Y,\u00a0Bado I<\/strong>, Wang H, Zhang W, Rosen JM, Zhang XH. Metastasis Organotropism: Redefining the Congenial Soil.\u00a0Dev Cell\u00a0<\/em> 49 (3). Read more<\/a><\/span>.<\/span><\/p>\n Zhang W,\u00a0Bado I<\/strong>, Wang H, Lo HC, Zhang XH. Bone Metastasis: Find Your Niche and Fit in.\u00a0Trends Cancer<\/em> 52 (2). Read more<\/a><\/span>.<\/span><\/p>\n 2018<\/strong><\/span><\/p>\n Wang H, Tian L, Liu J, Goldstein A,\u00a0Bado I<\/strong>, Zhang W, Arenkiel BR, Li Z, Yang M, Du S, Zhao H, Rowley DR, Wong STC, Gugala Z, Zhang XH. The osteogenic niche is a calcium reservoir of boe micrometastases and confers unexpected therapeutic vulnerability.\u00a0Cancer Cell<\/em> 34 (5). Read more<\/a><\/span>.<\/span><\/p>\n Bado I<\/strong>, Pham E, Soibam B, Nikolos F, Gustafsson J\u00c5, Thomas C. ER\u03b2\u00a0alters the chemosensitivity of luminal breast cancer cells by regulating p53 function.\u00a0Oncotarget<\/em>\u00a09 (32).\u00a0<\/em>Read more<\/a><\/span>.<\/span><\/p>\n Nikolos F, Thomas C,\u00a0Bado I<\/strong>,\u00a0Gustafsson J\u00c5. ER\u03b2 sensitizes NSCLC to chemotherapy by regulating DNA damage response.\u00a0Mol Cancer Res<\/em> 16 (2). Read more<\/a><\/span>.<\/span><\/p>\n 2017<\/strong><\/span><\/p>\n Bado I<\/strong>, Nikolos F, Rajapaksa, Wu W, Castaneda J, Krishnamurthy S, Webb P,\u00a0Gustafsson J\u00c5, Thomas C. Somatic loss of estrogen receptor beta and p53 synergize to induce breast tumorigenesis.\u00a0Breast Cancer Res<\/em> 19 (1). Read more<\/a><\/span>.<\/span><\/p>\n 2016<\/strong><\/span><\/p>\n Bado I<\/strong>,\u00a0Nikolos F, Rajapaksa,\u00a0Gustafsson J\u00c5, Thomas C.\u00a0ER\u03b2 decreases the invasiveness of triple-negative breast cancer cells by regulating mutant p53 oncogenic function.\u00a0Oncotarget<\/em> 7 (12). Read more<\/a><\/span>.<\/span><\/p>\n 2014<\/strong><\/span><\/p>\n Nikolos F,\u00a0 Thomas C, Rajapaksa,\u00a0Bado I<\/strong>,\u00a0Gustafsson J\u00c5.\u00a0ER\u03b2 regulates NSCLC phenotypes by controlling oncogenic RAS signaling.\u00a0Mol Cancer Res<\/em> 12 (6). Read more<\/a><\/span>.<\/span><\/p>\n [\/et_pb_text][\/et_pb_column][\/et_pb_row][\/et_pb_section]<\/p>\n","protected":false},"excerpt":{"rendered":" 2025 Bado IL (Corresponding). Deterministic Role of FOXF2 in Organ-Specific Macrometastasis Transition. Cancer Res. Read more. Alam R, Reva A, Edwards DG, Lege BM, Munoz-Arcos LS, Reduzzi C, Singh S, Hao X, Wu YH, Tian Z, Natalee LM, Damle G, Demircioglu D, Wang Y, Wu L, Molteni E, Hasson D, Lim B, Gugala Z, Chipuk […]<\/p>\n","protected":false},"author":393,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_et_pb_use_builder":"on","_et_pb_old_content":"","_et_gb_content_width":"","footnotes":""},"class_list":["post-97","page","type-page","status-publish","hentry"],"aioseo_notices":[],"_links":{"self":[{"href":"https:\/\/labs.icahn.mssm.edu\/badolab\/wp-json\/wp\/v2\/pages\/97","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/labs.icahn.mssm.edu\/badolab\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/labs.icahn.mssm.edu\/badolab\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/labs.icahn.mssm.edu\/badolab\/wp-json\/wp\/v2\/users\/393"}],"replies":[{"embeddable":true,"href":"https:\/\/labs.icahn.mssm.edu\/badolab\/wp-json\/wp\/v2\/comments?post=97"}],"version-history":[{"count":17,"href":"https:\/\/labs.icahn.mssm.edu\/badolab\/wp-json\/wp\/v2\/pages\/97\/revisions"}],"predecessor-version":[{"id":343,"href":"https:\/\/labs.icahn.mssm.edu\/badolab\/wp-json\/wp\/v2\/pages\/97\/revisions\/343"}],"wp:attachment":[{"href":"https:\/\/labs.icahn.mssm.edu\/badolab\/wp-json\/wp\/v2\/media?parent=97"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}