{"id":3010,"date":"2022-12-21T12:17:26","date_gmt":"2022-12-21T17:17:26","guid":{"rendered":"https:\/\/labs.icahn.mssm.edu\/design\/?page_id=3010"},"modified":"2026-06-01T13:31:03","modified_gmt":"2026-06-01T17:31:03","slug":"research","status":"publish","type":"page","link":"https:\/\/labs.icahn.mssm.edu\/bachilab\/research\/","title":{"rendered":"Research"},"content":{"rendered":"

[et_pb_section fb_built=”1″ admin_label=”Fullwidth Header – Background Title Description – no slider – Section 1″ module_class=”header-title-desciption-no-slider-section1″ _builder_version=”4.16″ _module_preset=”default” background_color=”rgba(0,174,239,0.09)” background_enable_color=”off” background_image=”https:\/\/labs.icahn.mssm.edu\/placeholder4\/wp-content\/uploads\/sites\/634\/2022\/07\/ai-002-1.jpg” parallax=”on” custom_padding=”||||false|false” bottom_divider_style=”ramp2″ bottom_divider_color=”#FFFFFF” bottom_divider_height=”11vw” bottom_divider_arrangement=”above_content” saved_tabs=”all” locked=”off” collapsed=”on” global_colors_info=”{}”][et_pb_row column_structure=”1_2,1_2″ _builder_version=”4.16″ _module_preset=”default” background_color=”RGBA(0,0,0,0)” border_color_all=”RGBA(0,0,0,0)” global_colors_info=”{}”][et_pb_column type=”1_2″ _builder_version=”4.16″ _module_preset=”default” custom_padding=”10%||8vw||false|false” custom_padding_tablet=”0vw||0vw||true|false” custom_padding_phone=”” custom_padding_last_edited=”on|tablet” global_colors_info=”{}”][et_pb_text admin_label=”Text – Title” _builder_version=”4.16″ _module_preset=”b3e3ff14-5f5c-4608-8ecf-1885ce3da7aa” header_font=”||||||||” header_text_color=”#FFFFFF” header_font_size=”48px” header_line_height=”60px” custom_margin=”||10px||false|false” header_font_size_tablet=”40px” header_font_size_phone=”24px” header_font_size_last_edited=”on|desktop” global_colors_info=”{}”]<\/p>\n

Research<\/strong><\/h1>\n

[\/et_pb_text][et_pb_text admin_label=”Text – Description” _builder_version=”4.27.4″ _module_preset=”da86b6f0-f83c-4c7c-bdd8-3019777ddffe” text_font=”||||||||” text_text_color=”#FFFFFF” text_font_size=”20px” text_line_height=”32px” text_font_size_tablet=”15px” text_font_size_phone=”14px” text_font_size_last_edited=”on|desktop” global_colors_info=”{}”][\/et_pb_text][\/et_pb_column][et_pb_column type=”1_2″ _builder_version=”4.16″ _module_preset=”default” background_color=”RGBA(0,0,0,0)” global_colors_info=”{}”][\/et_pb_column][\/et_pb_row][\/et_pb_section][et_pb_section fb_built=”1″ _builder_version=”4.27.4″ _module_preset=”default” global_colors_info=”{}”][et_pb_row _builder_version=”4.27.4″ _module_preset=”default” global_colors_info=”{}”][et_pb_column type=”4_4″ _builder_version=”4.27.4″ _module_preset=”default” global_colors_info=”{}”][et_pb_text _builder_version=”4.27.4″ _module_preset=”default” global_colors_info=”{}”]<\/p>\n

Interested in participating in our\u00a0Pathophysiological Mechanisms of Cannabidiol in Stress Regulation<\/a>\u00a0study?<\/p>\n

Click\u00a0here<\/a>\u00a0to fill out our pre-screen survey. If you are eligible we will contact you to schedule your first screening visit.\u00a0<\/p>\n

[\/et_pb_text][\/et_pb_column][\/et_pb_row][\/et_pb_section][et_pb_section fb_built=”1″ admin_label=”Section 27 – Two Column – Title Over Text Over Button Next to Image” module_class=”section27_two_column_title_over_txt_over_btn_next_to_img” _builder_version=”4.16″ _module_preset=”default” background_image=”https:\/\/labs.icahn.mssm.edu\/placeholder4\/wp-content\/uploads\/sites\/634\/2022\/12\/9-alt.png” parallax=”on” parallax_method=”off” locked=”off” collapsed=”off” global_colors_info=”{}”][et_pb_row column_structure=”1_2,1_2″ _builder_version=”4.9.0″ module_alignment=”center” custom_margin=”|||” custom_margin_tablet=”” custom_margin_phone=”” custom_margin_last_edited=”on|phone” custom_padding=”||150px|||” global_module=”3003″ collapsed=”off” global_colors_info=”{}”][et_pb_column type=”1_2″ _builder_version=”4.16″ background_color_gradient_direction=”35deg” custom_padding=”|60px||” global_colors_info=”{}” custom_padding__hover=”|||”][et_pb_text _builder_version=”4.27.4″ text_font=”||||||||” text_text_color=”#141414″ text_line_height=”1.9em” header_font=”||||||||” header_2_font=”||||||||” module_alignment=”center” custom_margin=”||30px|” global_colors_info=”{}”]<\/p>\n

Pathophysiological Mechanisms of Cannabidiol in Stress Regulation<\/h2>\n

This is a study of stress system neurobiological mechanisms and the potential role of cannabidiol (CBD) in ameliorating acute stress responsivity effects in young adults at high-risk for psychopathology.<\/p>\n

NCT07278505<\/a><\/h6>\n
NIMH 1R01MH139940-01<\/h6>\n
05\/01\/2025 – 04\/30\/2030<\/h6>\n

[\/et_pb_text][et_pb_button button_url=”https:\/\/labs.icahn.mssm.edu\/design\/option1-research” button_text=”Read More” disabled_on=”on|on|on” _builder_version=”4.16″ _module_preset=”default” custom_button=”on” button_text_color=”#FFFFFF” button_bg_color=”#00AEEF” button_border_radius=”0px” box_shadow_style=”preset1″ disabled=”on” locked=”off” global_colors_info=”{}”][\/et_pb_button][\/et_pb_column][et_pb_column type=”1_2″ module_class=”imageallignment” _builder_version=”4.16″ background_color=”RGBA(0,0,0,0)” use_background_color_gradient=”on” background_color_gradient_direction=”115deg” background_color_gradient_stops=”#00aeef 0%|#221f72 100%” background_color_gradient_start=”#00aeef” background_color_gradient_end=”#221f72″ custom_padding=”|||” global_colors_info=”{}” custom_padding__hover=”|||” custom_css_main_element_last_edited=”on|desktop” custom_css_main_element_tablet=”margin-top:60px!important” custom_css_main_element_phone=”margin-top:60px!important”][et_pb_image src=”https:\/\/labs.icahn.mssm.edu\/bachilab3\/wp-content\/uploads\/sites\/634\/2026\/03\/Screenshot-2025-11-28-at-12.06.57-PM-e1766237125666.png” title_text=”Screenshot-2025-11-28-at-12.06.57-PM-e1766237125666″ align=”center” _builder_version=”4.27.4″ background_color=”#221F72″ width=”74%” module_alignment=”center” custom_margin=”43px|40px|43px|-40px|false|false” custom_margin_tablet=”” custom_margin_phone=”-40px|40px|40px|-40px|false|false” custom_margin_last_edited=”on|phone” custom_padding=”|||” animation_style=”zoom” animation_direction=”right” animation_intensity_zoom=”6%” animation_starting_opacity=”100%” always_center_on_mobile=”off” global_colors_info=”{}”][\/et_pb_image][\/et_pb_column][\/et_pb_row][et_pb_row column_structure=”1_2,1_2″ make_equal=”on” _builder_version=”4.9.0″ module_alignment=”center” custom_margin=”|auto|150px|auto||” custom_padding=”0px||0px|” global_module=”3004″ collapsed=”off” global_colors_info=”{}”][et_pb_column type=”1_2″ _builder_version=”4.16″ background_color=”#00AEEF” use_background_color_gradient=”on” background_color_gradient_direction=”33deg” background_color_gradient_stops=”#00aeef 0%|#d80b8c 100%” background_color_gradient_start=”#00aeef” background_color_gradient_end=”#d80b8c” background_enable_image=”off” parallax=”on” custom_padding=”|5%||5%” global_colors_info=”{}” custom_padding__hover=”|||”][et_pb_image src=”https:\/\/labs.icahn.mssm.edu\/bachilab3\/wp-content\/uploads\/sites\/634\/2026\/03\/ctnlogo.jpg” title_text=”ctnlogo” force_fullwidth=”on” _builder_version=”4.27.4″ _module_preset=”default” custom_margin=”187px||||false|false” global_colors_info=”{}”][\/et_pb_image][\/et_pb_column][et_pb_column type=”1_2″ _builder_version=”4.16″ custom_padding=”40px|40px|40px|40px” global_colors_info=”{}” custom_padding__hover=”|||”][et_pb_text _builder_version=”4.16″ text_font=”||||||||” text_text_color=”#141414″ text_line_height=”1.9em” header_font=”||||||||” header_2_font=”||||||||” module_alignment=”center” custom_margin=”||30px|” global_colors_info=”{}”]<\/p>\n

NIDA Clinical Trials Network: Big South\/West Node 2025 Renewal Application<\/h2>\n

Sub-award: Mount Sinai\u00a0<\/strong><\/span><\/h2>\n

As a key site within the Big South\/West Node of the NIDA Clinical Trials Network, our team contributes clinical, scientific, and operational expertise to multi-site trials focused on developing and evaluating innovative treatments for stimulant use disorders (StUD). Through high-quality site performance, participation in protocol development, and engagement in implementation science initiatives, we support the Node\u2019s mission to advance rigorous, scalable interventions for addiction.<\/p>\n

Dates: 03\/01\/2025 – 02\/28\/2032<\/h6>\n

[\/et_pb_text][et_pb_button button_url=”https:\/\/labs.icahn.mssm.edu\/design\/option1-research” button_text=”Read More” disabled_on=”on|on|on” _builder_version=”4.16″ _module_preset=”default” custom_button=”on” button_text_color=”#FFFFFF” button_bg_color=”#00AEEF” button_border_radius=”0px” box_shadow_style=”preset1″ disabled=”on” locked=”off” global_colors_info=”{}”][\/et_pb_button][\/et_pb_column][\/et_pb_row][et_pb_row column_structure=”1_2,1_2″ make_equal=”on” _builder_version=”4.9.0″ module_alignment=”center” custom_margin=”|auto|-1px|auto||” custom_padding=”0px|0px|0px|0px” global_module=”3005″ collapsed=”off” global_colors_info=”{}”][et_pb_column type=”1_2″ _builder_version=”4.16″ background_color_gradient_direction=”35deg” custom_padding=”40px|40px|40px|40px” global_colors_info=”{}” custom_padding__hover=”|||”][et_pb_text _builder_version=”4.27.4″ text_font=”||||||||” text_text_color=”#141414″ text_line_height=”1.9em” header_font=”||||||||” header_2_font=”||||||||” module_alignment=”center” custom_margin=”||30px|” global_colors_info=”{}”]<\/p>\n

Randomized, Placebo-Controlled Trial of Extended-Release Naltrexone and Monthly Extended-Release Buprenorphine for Cocaine Use Disorder (CURB-2)<\/span><\/strong><\/h2>\n

This is an 8-week, double-blind, randomized placebo-controlled trial to determine the efficacy of a combination of Extended-Release Naltrexone (XR-NTR) and Monthly Extended-Release Buprenorphine (XR_BUP) compared to placebo injections (PBO-Inj) for the treatment of Cocaine Use Disorder. This is a 12-site study.<\/p>\n

NCT05262270<\/a><\/h6>\n
NIDA UG1DA020024:\u00a0CTN Protocol 0109<\/h6>\n
08\/01\/2022 – 09\/30\/2025<\/h6>\n
(Study Closeout in Progress)<\/h6>\n

 <\/p>\n

[\/et_pb_text][et_pb_button button_url=”https:\/\/labs.icahn.mssm.edu\/design\/option1-research” button_text=”Read More” disabled_on=”on|on|on” _builder_version=”4.16″ _module_preset=”default” custom_button=”on” button_text_color=”#FFFFFF” button_bg_color=”#00AEEF” button_border_radius=”0px” box_shadow_style=”preset1″ disabled=”on” locked=”off” global_colors_info=”{}”][\/et_pb_button][\/et_pb_column][et_pb_column type=”1_2″ _builder_version=”4.16″ background_color=”#00AEEF” use_background_color_gradient=”on” background_color_gradient_direction=”33deg” background_color_gradient_stops=”#221f72 0%|#d80b8c 100%” background_color_gradient_start=”#221f72″ background_color_gradient_end=”#d80b8c” background_enable_image=”off” parallax=”on” custom_padding=”|5%||5%” global_colors_info=”{}” custom_padding__hover=”|||”][et_pb_image src=”https:\/\/labs.icahn.mssm.edu\/bachilab3\/wp-content\/uploads\/sites\/634\/2026\/03\/curb2-logo.png” title_text=”curb2 logo” align=”center” align_tablet=”center” align_phone=”” align_last_edited=”on|desktop” _builder_version=”4.27.4″ custom_margin=”142px||0px||false|false” custom_padding=”|||” animation_style=”zoom” animation_direction=”left” animation_intensity_zoom=”10%” animation_starting_opacity=”100%” global_colors_info=”{}”][\/et_pb_image][et_pb_image src=”https:\/\/labs.icahn.mssm.edu\/bachilab3\/wp-content\/uploads\/sites\/634\/2026\/03\/ctnlogo.jpg” title_text=”ctnlogo” align=”center” _builder_version=”4.27.4″ _module_preset=”default” custom_padding=”27px||||false|false” global_colors_info=”{}”][\/et_pb_image][\/et_pb_column][\/et_pb_row][\/et_pb_section][et_pb_section fb_built=”1″ disabled_on=”off|off|off” admin_label=”Footer Fullwidth – Section 13″ module_class=”footer-section” _builder_version=”4.27.4″ background_color=”#c7eafb” background_image=”https:\/\/labs.icahn.mssm.edu\/placeholder4\/wp-content\/uploads\/sites\/634\/2022\/10\/Rectangle-3.png” max_width=”100%” max_width_tablet=”” max_width_phone=”” max_width_last_edited=”on|phone” module_alignment=”center” custom_margin=”0px|||176px|false|false” custom_padding=”0px|0px|0px|0px|false|false” animation_style=”slide” animation_direction=”bottom” animation_intensity_slide=”14%” animation_starting_opacity=”100%” global_module=”3741″ saved_tabs=”all” locked=”off” collapsed=”off” global_colors_info=”{}”][et_pb_row _builder_version=”4.27.4″ _module_preset=”default” global_colors_info=”{}”][et_pb_column type=”4_4″ _builder_version=”4.27.4″ _module_preset=”default” global_colors_info=”{}”][et_pb_text _builder_version=”4.27.4″ _module_preset=”default” header_text_color=”#FFFFFF” header_2_text_color=”#FFFFFF” global_colors_info=”{}”]<\/p>\n

Contact Us<\/strong><\/h2>\n

[\/et_pb_text][\/et_pb_column][\/et_pb_row][et_pb_row column_structure=”1_3,1_3,1_3″ _builder_version=”4.16″ background_color=”RGBA(0,0,0,0)” background_color_gradient_direction=”38deg” module_alignment=”center” custom_margin=”|auto|-2px|auto||” custom_padding=”0px|||||” locked=”off” collapsed=”off” global_colors_info=”{}”][et_pb_column type=”1_3″ _builder_version=”4.16″ custom_padding=”|||” global_colors_info=”{}” custom_padding__hover=”|||”][et_pb_text _builder_version=”4.27.4″ _module_preset=”default” text_font=”||||||||” text_text_color=”#FFFFFF” text_line_height=”22px” custom_padding=”||0px|||” global_colors_info=”{}”]<\/p>\n

Lab Address<\/strong>
1399 Park Avenue
New York, NY 10029<\/span><\/p>\n

[\/et_pb_text][\/et_pb_column][et_pb_column type=”1_3″ _builder_version=”4.16″ custom_padding=”|||” global_colors_info=”{}” custom_padding__hover=”|||”][et_pb_text _builder_version=”4.27.4″ text_font=”||||||||” text_text_color=”#FFFFFF” text_line_height=”1.25em” header_font=”||||||||” header_4_font=”|700||on|||||” header_4_font_size=”16px” header_4_letter_spacing=”1px” header_4_line_height=”1.5em” background_layout=”dark” custom_margin=”|4px||||” locked=”off” global_colors_info=”{}”]<\/p>\n

E-mail
<\/strong>bachilab@mssm.edu<\/p>\n

Phone
<\/strong>Tel: 646-984-3519<\/p>\n

[\/et_pb_text][\/et_pb_column][et_pb_column type=”1_3″ _builder_version=”4.16″ custom_padding=”|||” global_colors_info=”{}” custom_padding__hover=”|||”][et_pb_text _builder_version=”4.27.4″ text_font=”||||||||” text_text_color=”#FFFFFF” text_line_height=”1.25em” header_font=”||||||||” header_4_font=”|700||on|||||” header_4_font_size=”16px” header_4_letter_spacing=”1px” header_4_line_height=”1.5em” background_layout=”dark” locked=”off” global_colors_info=”{}”]<\/p>\n

Mailing Address <\/strong>
Bachi Lab
Icahn School of Medicine at Mount Sinai
One Gustave L. Levy Place
Annenberg
New York, NY 10029<\/span><\/p>\n

[\/et_pb_text][\/et_pb_column][\/et_pb_row][\/et_pb_section]<\/p>\n","protected":false},"excerpt":{"rendered":"

ResearchInterested in participating in our\u00a0Pathophysiological Mechanisms of Cannabidiol in Stress Regulation\u00a0study? Click\u00a0here\u00a0to fill out our pre-screen survey. If you are eligible we will contact you to schedule your first screening visit.\u00a0Pathophysiological Mechanisms of Cannabidiol in Stress Regulation This is a study of stress system neurobiological mechanisms and the potential role of cannabidiol (CBD) in ameliorating […]<\/p>\n","protected":false},"author":545,"featured_media":0,"parent":0,"menu_order":3,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_et_pb_use_builder":"on","_et_pb_old_content":"","_et_gb_content_width":"","inline_featured_image":false,"footnotes":""},"class_list":["post-3010","page","type-page","status-publish","hentry"],"aioseo_notices":[],"_links":{"self":[{"href":"https:\/\/labs.icahn.mssm.edu\/bachilab\/wp-json\/wp\/v2\/pages\/3010","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/labs.icahn.mssm.edu\/bachilab\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/labs.icahn.mssm.edu\/bachilab\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/labs.icahn.mssm.edu\/bachilab\/wp-json\/wp\/v2\/users\/545"}],"replies":[{"embeddable":true,"href":"https:\/\/labs.icahn.mssm.edu\/bachilab\/wp-json\/wp\/v2\/comments?post=3010"}],"version-history":[{"count":15,"href":"https:\/\/labs.icahn.mssm.edu\/bachilab\/wp-json\/wp\/v2\/pages\/3010\/revisions"}],"predecessor-version":[{"id":4767,"href":"https:\/\/labs.icahn.mssm.edu\/bachilab\/wp-json\/wp\/v2\/pages\/3010\/revisions\/4767"}],"wp:attachment":[{"href":"https:\/\/labs.icahn.mssm.edu\/bachilab\/wp-json\/wp\/v2\/media?parent=3010"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}