
{"id":3010,"date":"2022-12-21T12:17:26","date_gmt":"2022-12-21T17:17:26","guid":{"rendered":"https:\/\/labs.icahn.mssm.edu\/design\/?page_id=3010"},"modified":"2026-05-05T17:35:10","modified_gmt":"2026-05-05T21:35:10","slug":"research","status":"publish","type":"page","link":"https:\/\/labs.icahn.mssm.edu\/bachilab\/research\/","title":{"rendered":"Research"},"content":{"rendered":"<p>[et_pb_section fb_built=&#8221;1&#8243; admin_label=&#8221;Fullwidth Header &#8211; Background Title Description &#8211; no slider &#8211; Section 1&#8243; module_class=&#8221;header-title-desciption-no-slider-section1&#8243; _builder_version=&#8221;4.16&#8243; _module_preset=&#8221;default&#8221; background_color=&#8221;rgba(0,174,239,0.09)&#8221; background_enable_color=&#8221;off&#8221; background_image=&#8221;https:\/\/labs.icahn.mssm.edu\/placeholder4\/wp-content\/uploads\/sites\/634\/2022\/07\/ai-002-1.jpg&#8221; parallax=&#8221;on&#8221; custom_padding=&#8221;||||false|false&#8221; bottom_divider_style=&#8221;ramp2&#8243; bottom_divider_color=&#8221;#FFFFFF&#8221; bottom_divider_height=&#8221;11vw&#8221; bottom_divider_arrangement=&#8221;above_content&#8221; saved_tabs=&#8221;all&#8221; locked=&#8221;on&#8221; collapsed=&#8221;on&#8221; global_colors_info=&#8221;{}&#8221;][et_pb_row column_structure=&#8221;1_2,1_2&#8243; _builder_version=&#8221;4.16&#8243; _module_preset=&#8221;default&#8221; background_color=&#8221;RGBA(0,0,0,0)&#8221; border_color_all=&#8221;RGBA(0,0,0,0)&#8221; global_colors_info=&#8221;{}&#8221;][et_pb_column type=&#8221;1_2&#8243; _builder_version=&#8221;4.16&#8243; _module_preset=&#8221;default&#8221; custom_padding=&#8221;10%||8vw||false|false&#8221; custom_padding_tablet=&#8221;0vw||0vw||true|false&#8221; custom_padding_phone=&#8221;&#8221; custom_padding_last_edited=&#8221;on|tablet&#8221; global_colors_info=&#8221;{}&#8221;][et_pb_text admin_label=&#8221;Text &#8211; Title&#8221; _builder_version=&#8221;4.16&#8243; _module_preset=&#8221;b3e3ff14-5f5c-4608-8ecf-1885ce3da7aa&#8221; header_font=&#8221;||||||||&#8221; header_text_color=&#8221;#FFFFFF&#8221; header_font_size=&#8221;48px&#8221; header_line_height=&#8221;60px&#8221; custom_margin=&#8221;||10px||false|false&#8221; header_font_size_tablet=&#8221;40px&#8221; header_font_size_phone=&#8221;24px&#8221; header_font_size_last_edited=&#8221;on|desktop&#8221; global_colors_info=&#8221;{}&#8221;]<\/p>\n<h1><strong>Research<\/strong><\/h1>\n<p>[\/et_pb_text][et_pb_text admin_label=&#8221;Text &#8211; Description&#8221; _builder_version=&#8221;4.16&#8243; _module_preset=&#8221;da86b6f0-f83c-4c7c-bdd8-3019777ddffe&#8221; text_font=&#8221;||||||||&#8221; text_text_color=&#8221;#FFFFFF&#8221; text_font_size=&#8221;20px&#8221; text_line_height=&#8221;32px&#8221; text_font_size_tablet=&#8221;15px&#8221; text_font_size_phone=&#8221;14px&#8221; text_font_size_last_edited=&#8221;on|desktop&#8221; global_colors_info=&#8221;{}&#8221;]<\/p>\n<p>Our current research focuses on birth of the hair follicle niche, growth control and regeneration, and tissue regression and reorganization.<\/p>\n<p>[\/et_pb_text][\/et_pb_column][et_pb_column type=&#8221;1_2&#8243; _builder_version=&#8221;4.16&#8243; _module_preset=&#8221;default&#8221; background_color=&#8221;RGBA(0,0,0,0)&#8221; global_colors_info=&#8221;{}&#8221;][\/et_pb_column][\/et_pb_row][\/et_pb_section][et_pb_section fb_built=&#8221;1&#8243; _builder_version=&#8221;4.27.4&#8243; _module_preset=&#8221;default&#8221; global_colors_info=&#8221;{}&#8221;][et_pb_row _builder_version=&#8221;4.27.4&#8243; _module_preset=&#8221;default&#8221; global_colors_info=&#8221;{}&#8221;][et_pb_column type=&#8221;4_4&#8243; _builder_version=&#8221;4.27.4&#8243; _module_preset=&#8221;default&#8221; global_colors_info=&#8221;{}&#8221;][et_pb_text _builder_version=&#8221;4.27.4&#8243; _module_preset=&#8221;default&#8221; global_colors_info=&#8221;{}&#8221;]<\/p>\n<p>Interested in participating in our\u00a0<a href=\"https:\/\/labs.icahn.mssm.edu\/bachilab2\/research\/\">Pathophysiological Mechanisms of Cannabidiol in Stress Regulation<\/a>\u00a0study?<\/p>\n<p>Click\u00a0<a href=\"https:\/\/redcap.mountsinai.org\/redcap\/surveys\/?s=M9CWHXECDLTWDHFR\">here<\/a>\u00a0to fill out our pre-screen survey. If you are eligible we will contact you to schedule your first screening visit.\u00a0<\/p>\n<p>[\/et_pb_text][\/et_pb_column][\/et_pb_row][\/et_pb_section][et_pb_section fb_built=&#8221;1&#8243; admin_label=&#8221;Section 27 &#8211; Two Column &#8211; Title Over Text Over Button Next to Image&#8221; module_class=&#8221;section27_two_column_title_over_txt_over_btn_next_to_img&#8221; _builder_version=&#8221;4.16&#8243; _module_preset=&#8221;default&#8221; background_image=&#8221;https:\/\/labs.icahn.mssm.edu\/placeholder4\/wp-content\/uploads\/sites\/634\/2022\/12\/9-alt.png&#8221; parallax=&#8221;on&#8221; parallax_method=&#8221;off&#8221; locked=&#8221;off&#8221; collapsed=&#8221;off&#8221; global_colors_info=&#8221;{}&#8221;][et_pb_row column_structure=&#8221;1_2,1_2&#8243; _builder_version=&#8221;4.9.0&#8243; module_alignment=&#8221;center&#8221; custom_margin=&#8221;|||&#8221; custom_margin_tablet=&#8221;&#8221; custom_margin_phone=&#8221;&#8221; custom_margin_last_edited=&#8221;on|phone&#8221; custom_padding=&#8221;||150px|||&#8221; global_module=&#8221;3003&#8243; collapsed=&#8221;off&#8221; global_colors_info=&#8221;{}&#8221;][et_pb_column type=&#8221;1_2&#8243; _builder_version=&#8221;4.16&#8243; background_color_gradient_direction=&#8221;35deg&#8221; custom_padding=&#8221;|60px||&#8221; global_colors_info=&#8221;{}&#8221; custom_padding__hover=&#8221;|||&#8221;][et_pb_text _builder_version=&#8221;4.27.4&#8243; text_font=&#8221;||||||||&#8221; text_text_color=&#8221;#141414&#8243; text_line_height=&#8221;1.9em&#8221; header_font=&#8221;||||||||&#8221; header_2_font=&#8221;||||||||&#8221; module_alignment=&#8221;center&#8221; custom_margin=&#8221;||30px|&#8221; global_colors_info=&#8221;{}&#8221;]<\/p>\n<h2>Pathophysiological Mechanisms of Cannabidiol in Stress Regulation<\/h2>\n<p>This is a study of stress system neurobiological mechanisms and the potential role of cannabidiol (CBD) in ameliorating acute stress responsivity effects in young adults at high-risk for psychopathology.<\/p>\n<h6 style=\"text-align: right\"><a href=\"https:\/\/clinicaltrials.gov\/study\/NCT07278505\">NCT07278505<\/a><\/h6>\n<h6 style=\"text-align: right\">NIMH 1R01MH139940-01<\/h6>\n<h6 style=\"text-align: right\">05\/01\/2025 &#8211; 04\/30\/2030<\/h6>\n<p>[\/et_pb_text][et_pb_button button_url=&#8221;https:\/\/labs.icahn.mssm.edu\/design\/option1-research&#8221; button_text=&#8221;Read More&#8221; disabled_on=&#8221;on|on|on&#8221; _builder_version=&#8221;4.16&#8243; _module_preset=&#8221;default&#8221; custom_button=&#8221;on&#8221; button_text_color=&#8221;#FFFFFF&#8221; button_bg_color=&#8221;#00AEEF&#8221; button_border_radius=&#8221;0px&#8221; box_shadow_style=&#8221;preset1&#8243; disabled=&#8221;on&#8221; locked=&#8221;off&#8221; global_colors_info=&#8221;{}&#8221;][\/et_pb_button][\/et_pb_column][et_pb_column type=&#8221;1_2&#8243; module_class=&#8221;imageallignment&#8221; _builder_version=&#8221;4.16&#8243; background_color=&#8221;RGBA(0,0,0,0)&#8221; use_background_color_gradient=&#8221;on&#8221; background_color_gradient_direction=&#8221;115deg&#8221; background_color_gradient_stops=&#8221;#00aeef 0%|#221f72 100%&#8221; background_color_gradient_start=&#8221;#00aeef&#8221; background_color_gradient_end=&#8221;#221f72&#8243; 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animation_direction=&#8221;right&#8221; animation_intensity_zoom=&#8221;6%&#8221; animation_starting_opacity=&#8221;100%&#8221; always_center_on_mobile=&#8221;off&#8221; global_colors_info=&#8221;{}&#8221;][\/et_pb_image][\/et_pb_column][\/et_pb_row][et_pb_row column_structure=&#8221;1_2,1_2&#8243; make_equal=&#8221;on&#8221; _builder_version=&#8221;4.9.0&#8243; module_alignment=&#8221;center&#8221; custom_margin=&#8221;|auto|150px|auto||&#8221; custom_padding=&#8221;0px||0px|&#8221; global_module=&#8221;3004&#8243; collapsed=&#8221;off&#8221; global_colors_info=&#8221;{}&#8221;][et_pb_column type=&#8221;1_2&#8243; _builder_version=&#8221;4.16&#8243; background_color=&#8221;#00AEEF&#8221; use_background_color_gradient=&#8221;on&#8221; background_color_gradient_direction=&#8221;33deg&#8221; background_color_gradient_stops=&#8221;#00aeef 0%|#d80b8c 100%&#8221; background_color_gradient_start=&#8221;#00aeef&#8221; background_color_gradient_end=&#8221;#d80b8c&#8221; background_enable_image=&#8221;off&#8221; 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global_colors_info=&#8221;{}&#8221;]<\/p>\n<h2>NIDA Clinical Trials Network: Big South\/West Node 2025 Renewal Application<\/h2>\n<h2><span style=\"font-size: large\"><strong>Sub-award: Mount Sinai\u00a0<\/strong><\/span><\/h2>\n<p>As a key site within the Big South\/West Node of the NIDA Clinical Trials Network, our team contributes clinical, scientific, and operational expertise to multi-site trials focused on developing and evaluating innovative treatments for stimulant use disorders (StUD). Through high-quality site performance, participation in protocol development, and engagement in implementation science initiatives, we support the Node\u2019s mission to advance rigorous, scalable interventions for addiction.<\/p>\n<h6 style=\"text-align: right\">Dates: 03\/01\/2025 &#8211; 02\/28\/2032<\/h6>\n<p>[\/et_pb_text][et_pb_button button_url=&#8221;https:\/\/labs.icahn.mssm.edu\/design\/option1-research&#8221; button_text=&#8221;Read More&#8221; disabled_on=&#8221;on|on|on&#8221; _builder_version=&#8221;4.16&#8243; _module_preset=&#8221;default&#8221; custom_button=&#8221;on&#8221; button_text_color=&#8221;#FFFFFF&#8221; button_bg_color=&#8221;#00AEEF&#8221; button_border_radius=&#8221;0px&#8221; box_shadow_style=&#8221;preset1&#8243; disabled=&#8221;on&#8221; locked=&#8221;off&#8221; global_colors_info=&#8221;{}&#8221;][\/et_pb_button][\/et_pb_column][\/et_pb_row][et_pb_row column_structure=&#8221;1_2,1_2&#8243; make_equal=&#8221;on&#8221; _builder_version=&#8221;4.9.0&#8243; module_alignment=&#8221;center&#8221; custom_margin=&#8221;|auto|-1px|auto||&#8221; custom_padding=&#8221;0px|0px|0px|0px&#8221; global_module=&#8221;3005&#8243; collapsed=&#8221;off&#8221; global_colors_info=&#8221;{}&#8221;][et_pb_column type=&#8221;1_2&#8243; _builder_version=&#8221;4.16&#8243; background_color_gradient_direction=&#8221;35deg&#8221; custom_padding=&#8221;40px|40px|40px|40px&#8221; global_colors_info=&#8221;{}&#8221; custom_padding__hover=&#8221;|||&#8221;][et_pb_text _builder_version=&#8221;4.27.4&#8243; text_font=&#8221;||||||||&#8221; text_text_color=&#8221;#141414&#8243; text_line_height=&#8221;1.9em&#8221; header_font=&#8221;||||||||&#8221; header_2_font=&#8221;||||||||&#8221; module_alignment=&#8221;center&#8221; custom_margin=&#8221;||30px|&#8221; global_colors_info=&#8221;{}&#8221;]<\/p>\n<h2><strong><span data-olk-copy-source=\"MessageBody\">Randomized, Placebo-Controlled Trial of Extended-Release Naltrexone and Monthly Extended-Release Buprenorphine for Cocaine Use Disorder (CURB-2)<\/span><\/strong><\/h2>\n<p>This is an 8-week, double-blind, randomized placebo-controlled trial to determine the efficacy of a combination of Extended-Release Naltrexone (XR-NTR) and Monthly Extended-Release Buprenorphine (XR_BUP) compared to placebo injections (PBO-Inj) for the treatment of Cocaine Use Disorder. This is a 12-site study.<\/p>\n<h6 style=\"text-align: right\"><a href=\"https:\/\/clinicaltrials.gov\/study\/NCT05262270\">NCT05262270<\/a><\/h6>\n<h6 style=\"text-align: right\">NIDA UG1DA020024:\u00a0CTN Protocol 0109<\/h6>\n<h6 style=\"text-align: right\">08\/01\/2022 &#8211; 09\/30\/2025<\/h6>\n<h6 style=\"text-align: right\">(Study Closeout in Progress)<\/h6>\n<p>&nbsp;<\/p>\n<p>[\/et_pb_text][et_pb_button button_url=&#8221;https:\/\/labs.icahn.mssm.edu\/design\/option1-research&#8221; button_text=&#8221;Read More&#8221; disabled_on=&#8221;on|on|on&#8221; _builder_version=&#8221;4.16&#8243; _module_preset=&#8221;default&#8221; custom_button=&#8221;on&#8221; button_text_color=&#8221;#FFFFFF&#8221; button_bg_color=&#8221;#00AEEF&#8221; button_border_radius=&#8221;0px&#8221; box_shadow_style=&#8221;preset1&#8243; disabled=&#8221;on&#8221; locked=&#8221;off&#8221; global_colors_info=&#8221;{}&#8221;][\/et_pb_button][\/et_pb_column][et_pb_column type=&#8221;1_2&#8243; _builder_version=&#8221;4.16&#8243; 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animation_starting_opacity=&#8221;100%&#8221; global_colors_info=&#8221;{}&#8221;][\/et_pb_image][et_pb_image src=&#8221;https:\/\/labs.icahn.mssm.edu\/bachilab3\/wp-content\/uploads\/sites\/634\/2026\/03\/ctnlogo.jpg&#8221; title_text=&#8221;ctnlogo&#8221; align=&#8221;center&#8221; _builder_version=&#8221;4.27.4&#8243; _module_preset=&#8221;default&#8221; custom_padding=&#8221;27px||||false|false&#8221; global_colors_info=&#8221;{}&#8221;][\/et_pb_image][\/et_pb_column][\/et_pb_row][\/et_pb_section][et_pb_section fb_built=&#8221;1&#8243; disabled_on=&#8221;off|off|off&#8221; admin_label=&#8221;Footer Fullwidth &#8211; Section 13&#8243; module_class=&#8221;footer-section&#8221; _builder_version=&#8221;4.27.4&#8243; background_color=&#8221;#c7eafb&#8221; background_image=&#8221;https:\/\/labs.icahn.mssm.edu\/placeholder4\/wp-content\/uploads\/sites\/634\/2022\/10\/Rectangle-3.png&#8221; max_width=&#8221;100%&#8221; max_width_tablet=&#8221;&#8221; max_width_phone=&#8221;&#8221; max_width_last_edited=&#8221;on|phone&#8221; 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_builder_version=&#8221;4.16&#8243; background_color=&#8221;RGBA(0,0,0,0)&#8221; background_color_gradient_direction=&#8221;38deg&#8221; module_alignment=&#8221;center&#8221; custom_margin=&#8221;|auto|-2px|auto||&#8221; custom_padding=&#8221;0px|||||&#8221; locked=&#8221;off&#8221; collapsed=&#8221;on&#8221; global_colors_info=&#8221;{}&#8221;][et_pb_column type=&#8221;1_3&#8243; _builder_version=&#8221;4.16&#8243; custom_padding=&#8221;|||&#8221; global_colors_info=&#8221;{}&#8221; custom_padding__hover=&#8221;|||&#8221;][et_pb_text _builder_version=&#8221;4.27.4&#8243; _module_preset=&#8221;default&#8221; text_font=&#8221;||||||||&#8221; text_text_color=&#8221;#FFFFFF&#8221; text_line_height=&#8221;22px&#8221; custom_padding=&#8221;||0px|||&#8221; global_colors_info=&#8221;{}&#8221;]<\/p>\n<p style=\"text-align: center\"><span style=\"font-size: 16px\"><strong>Lab Address<\/strong><br \/>1399 Park Avenue<br \/>New York, NY 10029<\/span><\/p>\n<p>[\/et_pb_text][\/et_pb_column][et_pb_column type=&#8221;1_3&#8243; _builder_version=&#8221;4.16&#8243; custom_padding=&#8221;|||&#8221; global_colors_info=&#8221;{}&#8221; custom_padding__hover=&#8221;|||&#8221;][et_pb_text _builder_version=&#8221;4.27.4&#8243; text_font=&#8221;||||||||&#8221; text_text_color=&#8221;#FFFFFF&#8221; text_line_height=&#8221;1.25em&#8221; header_font=&#8221;||||||||&#8221; header_4_font=&#8221;|700||on|||||&#8221; header_4_font_size=&#8221;16px&#8221; header_4_letter_spacing=&#8221;1px&#8221; header_4_line_height=&#8221;1.5em&#8221; background_layout=&#8221;dark&#8221; custom_margin=&#8221;|4px||||&#8221; locked=&#8221;off&#8221; global_colors_info=&#8221;{}&#8221;]<\/p>\n<p style=\"text-align: center\"><strong>E-mail<br \/><\/strong>bachilab@mssm.edu<\/p>\n<p style=\"text-align: center\"><strong>Phone<br \/><\/strong>Tel: 646-984-3519<\/p>\n<p>[\/et_pb_text][\/et_pb_column][et_pb_column type=&#8221;1_3&#8243; _builder_version=&#8221;4.16&#8243; custom_padding=&#8221;|||&#8221; global_colors_info=&#8221;{}&#8221; custom_padding__hover=&#8221;|||&#8221;][et_pb_text _builder_version=&#8221;4.27.4&#8243; text_font=&#8221;||||||||&#8221; text_text_color=&#8221;#FFFFFF&#8221; text_line_height=&#8221;1.25em&#8221; header_font=&#8221;||||||||&#8221; header_4_font=&#8221;|700||on|||||&#8221; header_4_font_size=&#8221;16px&#8221; header_4_letter_spacing=&#8221;1px&#8221; header_4_line_height=&#8221;1.5em&#8221; background_layout=&#8221;dark&#8221; locked=&#8221;off&#8221; global_colors_info=&#8221;{}&#8221;]<\/p>\n<p style=\"text-align: center\"><span style=\"font-size: 16px\"><strong>Mailing Address <\/strong><br \/>Bachi Lab<br \/>Icahn School of Medicine at Mount Sinai<br \/>One Gustave L. Levy Place<br \/>Annenberg<br \/>New York, NY 10029<\/span><\/p>\n<p style=\"text-align: right\">[\/et_pb_text][\/et_pb_column][\/et_pb_row][\/et_pb_section]<\/p>\n","protected":false},"excerpt":{"rendered":"<p>ResearchOur current research focuses on birth of the hair follicle niche, growth control and regeneration, and tissue regression and reorganization.Interested in participating in our\u00a0Pathophysiological Mechanisms of Cannabidiol in Stress Regulation\u00a0study? Click\u00a0here\u00a0to fill out our pre-screen survey. If you are eligible we will contact you to schedule your first screening visit.\u00a0Pathophysiological Mechanisms of Cannabidiol in Stress [&hellip;]<\/p>\n","protected":false},"author":545,"featured_media":0,"parent":0,"menu_order":3,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_et_pb_use_builder":"on","_et_pb_old_content":"","_et_gb_content_width":"","inline_featured_image":false,"footnotes":""},"class_list":["post-3010","page","type-page","status-publish","hentry"],"aioseo_notices":[],"_links":{"self":[{"href":"https:\/\/labs.icahn.mssm.edu\/bachilab\/wp-json\/wp\/v2\/pages\/3010","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/labs.icahn.mssm.edu\/bachilab\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/labs.icahn.mssm.edu\/bachilab\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/labs.icahn.mssm.edu\/bachilab\/wp-json\/wp\/v2\/users\/545"}],"replies":[{"embeddable":true,"href":"https:\/\/labs.icahn.mssm.edu\/bachilab\/wp-json\/wp\/v2\/comments?post=3010"}],"version-history":[{"count":13,"href":"https:\/\/labs.icahn.mssm.edu\/bachilab\/wp-json\/wp\/v2\/pages\/3010\/revisions"}],"predecessor-version":[{"id":4704,"href":"https:\/\/labs.icahn.mssm.edu\/bachilab\/wp-json\/wp\/v2\/pages\/3010\/revisions\/4704"}],"wp:attachment":[{"href":"https:\/\/labs.icahn.mssm.edu\/bachilab\/wp-json\/wp\/v2\/media?parent=3010"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}