Interested in participating in our Pathophysiological Mechanisms of Cannabidiol in Stress Regulation study?
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Pathophysiological Mechanisms of Cannabidiol in Stress Regulation
This is a study of stress system neurobiological mechanisms and the potential role of cannabidiol (CBD) in ameliorating acute stress responsivity effects in young adults at high-risk for psychopathology.
NCT07278505
NIMH 1R01MH139940-01
05/01/2025 - 04/30/2030
NIDA Clinical Trials Network: Big South/West Node 2025 Renewal Application
Sub-award: Mount Sinai
As a key site within the Big South/West Node of the NIDA Clinical Trials Network, our team contributes clinical, scientific, and operational expertise to multi-site trials focused on developing and evaluating innovative treatments for stimulant use disorders (StUD). Through high-quality site performance, participation in protocol development, and engagement in implementation science initiatives, we support the Node’s mission to advance rigorous, scalable interventions for addiction.
Dates: 03/01/2025 - 02/28/2032
Randomized, Placebo-Controlled Trial of Extended-Release Naltrexone and Monthly Extended-Release Buprenorphine for Cocaine Use Disorder (CURB-2)
This is an 8-week, double-blind, randomized placebo-controlled trial to determine the efficacy of a combination of Extended-Release Naltrexone (XR-NTR) and Monthly Extended-Release Buprenorphine (XR_BUP) compared to placebo injections (PBO-Inj) for the treatment of Cocaine Use Disorder. This is a 12-site study.
NCT05262270
NIDA UG1DA020024: CTN Protocol 0109
08/01/2022 - 09/30/2025
(Study Closeout in Progress)
