{"id":106,"date":"2021-04-24T22:00:35","date_gmt":"2021-04-24T22:00:35","guid":{"rendered":"http:\/\/labs.icahn.mssm.edu\/abul-husnlab\/?page_id=106"},"modified":"2021-10-08T14:30:17","modified_gmt":"2021-10-08T14:30:17","slug":"publications","status":"publish","type":"page","link":"https:\/\/labs.icahn.mssm.edu\/abul-husnlab\/publications\/","title":{"rendered":"Publications"},"content":{"rendered":"

[et_pb_section fb_built=”1″ specialty=”on” _builder_version=”4.9.0″ _module_preset=”default”][et_pb_column type=”3_4″ specialty_columns=”3″ _builder_version=”3.25″ custom_padding=”|||” custom_padding__hover=”|||”][et_pb_row_inner _builder_version=”4.9.0″ _module_preset=”default”][et_pb_column_inner saved_specialty_column_type=”3_4″ _builder_version=”4.9.0″ _module_preset=”default”][et_pb_text _builder_version=”4.9.0″ _module_preset=”default” hover_enabled=”0″ sticky_enabled=”0″]<\/p>\n

A full list of publications can be found <\/strong>here<\/a><\/em><\/strong><\/span><\/h2>\n

[\/et_pb_text][et_pb_accordion _builder_version=”4.9.0″ _module_preset=”default” hover_enabled=”0″ sticky_enabled=”0″][et_pb_accordion_item _builder_version=”4.9.0″ _module_preset=”default” open=”on” title=”Selected publications on genomic medicine” hover_enabled=”0″ sticky_enabled=”0″]<\/p>\n

Implementing genomic screening in diverse populations<\/a><\/h4>\n

Genome Med<\/em><\/strong>. 2021 Feb 5;13(1):17. doi: 10.1186\/s13073-021-00832-y. PMID: 33546753; PMCID: PMC7863616.<\/p>\n

Genomic Screening Identifies Individuals at High Risk for Hereditary Transthyretin Amyloidosis<\/a><\/h4>\n

J Pers Med<\/em><\/strong>. 2021 Jan 15;11(1):49. doi: 10.3390\/jpm11010049. PMID: 33467513; PMCID: PMC7829706.<\/p>\n

Exome sequencing reveals a high prevalence of BRCA1 and BRCA2 founder variants in a diverse population-based biobank<\/a><\/h4>\n

Genome Med<\/em><\/strong>. 2019 Dec 31;12(1):2. doi: 10.1186\/s13073-019-0691-1. PMID: 31892343; PMCID: PMC6938627.<\/p>\n

Genetic identification of familial hypercholesterolemia within a single U.S. health care system<\/a><\/h4>\n

Science<\/em><\/strong>. 2016 Dec 23;354(6319):aaf7000. doi: 10.1126\/science.aaf7000. PMID: 28008010.<\/p>\n

[\/et_pb_accordion_item][et_pb_accordion_item _builder_version=”4.9.0″ _module_preset=”default” open=”off” title=”Selected publications on genomics research using EHRs” hover_enabled=”0″ sticky_enabled=”0″]<\/p>\n

Personalized Medicine and the Power of Electronic Health Records<\/a><\/h4>\n

Cell<\/em><\/strong>. 2019 Mar 21;177(1):58-69. doi: 10.1016\/j.cell.2019.02.039. PMID: 30901549; PMCID: PMC6921466.<\/p>\n

A Protein-Truncating HSD17B13 Variant and Protection from Chronic Liver Disease<\/a><\/h4>\n

N Engl J Med<\/em><\/strong>. 2018 Mar 22;378(12):1096-1106. doi: 10.1056\/NEJMoa1712191. PMID: 29562163; PMCID: PMC6668033.<\/p>\n

Distribution and clinical impact of functional variants in 50,726 whole-exome sequences from the DiscovEHR study<\/a><\/h4>\n

Science<\/em><\/strong>. 2016 Dec 23;354(6319):aaf6814. doi: 10.1126\/science.aaf6814. PMID: 28008009.<\/p>\n

Association of Arrhythmia-Related Genetic Variants With Phenotypes Documented in Electronic Medical Records<\/a><\/h4>\n

JAMA<\/em><\/strong>. 2016 Jan 5;315(1):47-57. doi: 10.1001\/jama.2015.17701. PMID: 26746457; PMCID: PMC4758131.<\/p>\n

 <\/p>\n

[\/et_pb_accordion_item][\/et_pb_accordion][\/et_pb_column_inner][\/et_pb_row_inner][\/et_pb_column][et_pb_column type=”1_4″ _builder_version=”3.25″ custom_padding=”|||” custom_padding__hover=”|||”][et_pb_sidebar _builder_version=”4.9.0″ _module_preset=”default”][\/et_pb_sidebar][\/et_pb_column][\/et_pb_section]<\/p>\n","protected":false},"excerpt":{"rendered":"

A full list of publications can be found hereImplementing genomic screening in diverse populations Genome Med. 2021 Feb 5;13(1):17. doi: 10.1186\/s13073-021-00832-y. PMID: 33546753; PMCID: PMC7863616. Genomic Screening Identifies Individuals at High Risk for Hereditary Transthyretin Amyloidosis J Pers Med. 2021 Jan 15;11(1):49. doi: 10.3390\/jpm11010049. PMID: 33467513; PMCID: PMC7829706. Exome sequencing reveals a high prevalence of […]<\/p>\n","protected":false},"author":9,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_et_pb_use_builder":"on","_et_pb_old_content":"

A full list of publications can be found <\/strong>here<\/a><\/em><\/strong><\/span><\/h2>

Selected publications on genomic medicine<\/strong><\/span><\/h2>

Retinol binding protein 4 as a screening biomarker for hereditary TTR amyloidosis in African American adults with TTR V142I<\/a><\/h3>

J Card Fail<\/strong>.<\/em> 2021 May 26;S1071-9164(21)00199-8. doi: 10.1016\/j.cardfail.2021.05.009.<\/span>\u00a0<\/span>Online ahead of print. PMID:\u00a034051348.<\/span><\/span><\/span><\/p>

CDH1 pathogenic variants and cancer risk in an unselected patient population<\/a><\/h3>

Fam Cancer<\/em><\/strong>. 2021 Apr 22. doi: 10.1007\/s10689-021-00257-x. Epub ahead of print. PMID: 33886068.<\/p>

Implementing genomic screening in diverse populations<\/a><\/h3>

Genome Med<\/em><\/strong>. 2021 Feb 5;13(1):17. doi: 10.1186\/s13073-021-00832-y. PMID: 33546753; PMCID: PMC7863616.<\/p>

Genomic Screening Identifies Individuals at High Risk for Hereditary Transthyretin Amyloidosis<\/a><\/h3>

J Pers Med<\/em><\/strong>. 2021 Jan 15;11(1):49. doi: 10.3390\/jpm11010049. PMID: 33467513; PMCID: PMC7829706.<\/p>

Lynch Syndrome-Associated Variants and Cancer Rates in an Ancestrally Diverse Biobank<\/a><\/h3>

JCO Precis Oncol<\/em><\/strong>. 2020 Nov 23;4:PO.20.00290. doi: 10.1200\/PO.20.00290. PMID: 33283134; PMCID: PMC7713527.<\/p>

Exome sequencing reveals a high prevalence of BRCA1 and BRCA2 founder variants in a diverse population-based biobank<\/a><\/h3>

Genome Med<\/em><\/strong>. 2019 Dec 31;12(1):2. doi: 10.1186\/s13073-019-0691-1. PMID: 31892343; PMCID: PMC6938627.<\/p>

Genetic identification of familial hypercholesterolemia within a single U.S. health care system<\/a><\/h3>

Science<\/em><\/strong>. 2016 Dec 23;354(6319):aaf7000. doi: 10.1126\/science.aaf7000. PMID: 28008010.<\/p>

Selected publications on genomics research using EHRs<\/strong><\/span><\/h2>

Toward a fine-scale population health monitoring system<\/a><\/h3>

Cell<\/em><\/strong>. 2021 Apr 15;184(8):2068-2083.e11. doi: 10.1016\/j.cell.2021.03.034. PMID: 33861964.<\/p>

A common variant in PNPLA3 is associated with age at diagnosis of NAFLD in patients from a multi-ethnic biobank<\/a><\/h3>

J Hepatol<\/em><\/strong>. 2020 Jun;72(6):1070-1081. doi: 10.1016\/j.jhep.2020.01.029. Epub 2020 Mar 5. PMID: 32145261; PMCID: PMC7840172.<\/p>

Association of the V122I Hereditary Transthyretin Amyloidosis Genetic Variant With Heart Failure Among Individuals of African or Hispanic\/Latino Ancestry<\/a><\/h3>

JAMA<\/em><\/strong>. 2019 Dec 10;322(22):2191-2202. doi: 10.1001\/jama.2019.17935. PMID: 31821430; PMCID: PMC7081752.<\/p>

Personalized Medicine and the Power of Electronic Health Records<\/a><\/h3>

Cell<\/em><\/strong>. 2019 Mar 21;177(1):58-69. doi: 10.1016\/j.cell.2019.02.039. PMID: 30901549; PMCID: PMC6921466.<\/p>

A Protein-Truncating HSD17B13 Variant and Protection from Chronic Liver Disease<\/a><\/h3>

N Engl J Med<\/em><\/strong>. 2018 Mar 22;378(12):1096-1106. doi: 10.1056\/NEJMoa1712191. PMID: 29562163; PMCID: PMC6668033.<\/p>

Genetic identification of a common collagen disease in puerto ricans via identity-by-descent mapping in a health system<\/a><\/h3>

Elife<\/em><\/strong>. 2017 Sep 12;6:e25060. doi: 10.7554\/eLife.25060. PMID: 28895531; PMCID: PMC5595434.<\/p>

Distribution and clinical impact of functional variants in 50,726 whole-exome sequences from the DiscovEHR study<\/a><\/h3>

Science<\/em><\/strong>. 2016 Dec 23;354(6319):aaf6814. doi: 10.1126\/science.aaf6814. PMID: 28008009.<\/p>

Association of Arrhythmia-Related Genetic Variants With Phenotypes Documented in Electronic Medical Records<\/a><\/h3>

JAMA<\/em><\/strong>. 2016 Jan 5;315(1):47-57. doi: 10.1001\/jama.2015.17701. PMID: 26746457; PMCID: PMC4758131.<\/p>

Other selected publications<\/strong><\/span><\/h2>

The intersection of genetics and COVID-19 in 2021: preview of the 2021 Rodney Howell Symposium (2021)<\/a><\/h3>

Genet Med<\/em><\/strong>. 2021 Mar 12:1\u20133. doi: 10.1038\/s41436-021-01113-0. Epub ahead of print. PMID: 33712732; PMCID: PMC7953182.<\/p>

GU\u00cdA: a digital platform to facilitate result disclosure in genetic counseling<\/a><\/h3>

Genet Med<\/em><\/strong>. 2021 Feb 2. doi: 10.1038\/s41436-020-01063-z. Epub ahead of print. PMID: 33531665.<\/p>

The NYCKidSeq project: study protocol for a randomized controlled trial incorporating genomics into the clinical care of diverse New York City children<\/a><\/h3>

Trials<\/strong><\/em> 22(1):56. doi: 10.1186\/s13063-020-04953-4. Erratum in: Trials. 2021 Feb 16;22(1):146. PMID: 33446240.<\/p>

COVID-19 outcomes and the human genome<\/a><\/h3>

Genet Med<\/em><\/strong>. 2020 Jul;22(7):1175-1177. doi: 10.1038\/s41436-020-0832-3. Epub 2020 May 12. PMID: 32393819.<\/p>

A stepwise approach to implementing pharmacogenetic testing in the primary care setting<\/a><\/h3>

Pharmacogenomics<\/em><\/strong>. 2019 Oct;20(15):1103-1112. doi: 10.2217\/pgs-2019-0053. PMID: 31588877; PMCID: PMC6854439.<\/p>

Healthcare provider education to support integration of pharmacogenomics in practice: the eMERGE Network experience<\/a><\/h3>

Pharmacogenomics<\/em><\/strong>. 2017 Jul;18(10):1013-1025. doi: 10.2217\/pgs-2017-0038. Epub 2017 Jun 22. PMID: 28639489; PMCID: PMC5941709.<\/p>

Implementing algorithm-guided warfarin dosing in an ethnically diverse patient population using electronic health records and pre-emptive CYP2C9 and VKORC1 genetic testing<\/a><\/h3>

Clin Pharmacol Ther<\/em><\/strong>. 2016 Nov;100(5):427-430. doi: 10.1002\/cpt.425. Epub 2016 Aug 18. PMID: 27393744; PMCID: PMC5638436.<\/p>

Medical student preparedness for an era of personalized medicine: findings from one US medical school<\/a><\/h3>

Per Med<\/em><\/strong>. 2016 Mar;13(2):129-141. doi: 10.2217\/pme.15.58. PMID: 27528879; PMCID: PMC4982654.<\/p>","_et_gb_content_width":"","footnotes":""},"class_list":["post-106","page","type-page","status-publish","hentry"],"aioseo_notices":[],"_links":{"self":[{"href":"https:\/\/labs.icahn.mssm.edu\/abul-husnlab\/wp-json\/wp\/v2\/pages\/106","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/labs.icahn.mssm.edu\/abul-husnlab\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/labs.icahn.mssm.edu\/abul-husnlab\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/labs.icahn.mssm.edu\/abul-husnlab\/wp-json\/wp\/v2\/users\/9"}],"replies":[{"embeddable":true,"href":"https:\/\/labs.icahn.mssm.edu\/abul-husnlab\/wp-json\/wp\/v2\/comments?post=106"}],"version-history":[{"count":37,"href":"https:\/\/labs.icahn.mssm.edu\/abul-husnlab\/wp-json\/wp\/v2\/pages\/106\/revisions"}],"predecessor-version":[{"id":731,"href":"https:\/\/labs.icahn.mssm.edu\/abul-husnlab\/wp-json\/wp\/v2\/pages\/106\/revisions\/731"}],"wp:attachment":[{"href":"https:\/\/labs.icahn.mssm.edu\/abul-husnlab\/wp-json\/wp\/v2\/media?parent=106"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}