{"id":8,"date":"2019-06-12T16:10:39","date_gmt":"2019-06-12T16:10:39","guid":{"rendered":"http:\/\/labs.icahn.mssm.edu\/ableslab\/?page_id=8"},"modified":"2026-03-06T16:22:43","modified_gmt":"2026-03-06T16:22:43","slug":"the-ables-lab-of-metabolic-psychiatry","status":"publish","type":"page","link":"https:\/\/labs.icahn.mssm.edu\/ableslab\/","title":{"rendered":"The Ables Lab of Metabolic Psychiatry"},"content":{"rendered":"

[et_pb_section fb_built=”1″ fullwidth=”on” disabled_on=”on|on|on” _builder_version=”4.16″ disabled=”on” global_colors_info=”{}”][et_pb_fullwidth_menu menu_id=”5″ submenu_direction=”downwards” fullwidth_menu=”off” _builder_version=”4.16″ global_colors_info=”{}”][\/et_pb_fullwidth_menu][\/et_pb_section][et_pb_section fb_built=”1″ fullwidth=”on” _builder_version=”4.16″ background_color=”#000000″ global_colors_info=”{}”][et_pb_fullwidth_slider show_pagination=”off” _builder_version=”4.16″ animation_style=”slide” animation_direction=”right” auto=”on” global_colors_info=”{}”][et_pb_slide heading=”Ables Laboratory” use_bg_overlay=”off” use_text_overlay=”off” _builder_version=”4.16″ use_background_color_gradient=”on” background_image=”https:\/\/labs.icahn.mssm.edu\/ableslab\/wp-content\/uploads\/sites\/306\/2019\/07\/amigo1-gfp-sst-nos1-ipn.jpg” button_on_hover=”on” global_colors_info=”{}” sticky_transition=”on”][\/et_pb_slide][et_pb_slide heading=”Lab of Metabolic Psychiatry” use_bg_overlay=”off” use_text_overlay=”off” _builder_version=”4.16″ use_background_color_gradient=”on” background_image=”https:\/\/labs.icahn.mssm.edu\/ableslab\/wp-content\/uploads\/sites\/306\/2019\/07\/epyc-gfp-amigo1-mcherry-nos1-ipn.jpg” button_on_hover=”on” global_colors_info=”{}” sticky_transition=”on”][\/et_pb_slide][\/et_pb_fullwidth_slider][\/et_pb_section][et_pb_section fb_built=”1″ module_id=”research” module_class=”research-section” _builder_version=”4.16″ global_colors_info=”{}”][et_pb_row column_structure=”3_4,1_4″ _builder_version=”4.16″ background_size=”initial” background_position=”top_left” background_repeat=”repeat” global_colors_info=”{}”][et_pb_column type=”3_4″ _builder_version=”4.16″ custom_padding=”|||” global_colors_info=”{}” custom_padding__hover=”|||”][et_pb_text admin_label=”research” _builder_version=”4.16″ global_colors_info=”{}”]<\/p>\n

Research<\/h3>\n

The goal of our research is to better understand the effects of chronic metabolic diseases, such as diabetes, on brain function. People with diabetes have double the rate of mental illness compared to those who don’t have diabetes and are twice as likely to not respond to current treatments. Currently, we use mouse models of diabetes to identify the ways in which chronic hyperglycemia can lead to behaviors associated with mental illness by exploring processes at the behavioral, circuit, cellular and molecular levels.\u00a0 A major focus of our work is on hyperglycemia-induced changes in gene expression within cholinergic neurons in the brain\u2019s reward circuitry. We also use operant models to explore how diabetes affects learning and response to rewards.\u00a0 In the near future, we plan to repeat many of these behavioral studies in people with diabetes or at risk of developing diabetes.<\/p>\n

PubMed publications<\/strong>
\nhttps:\/\/www.ncbi.nlm.nih.gov\/pubmed\/?term=ables+jl<\/a><\/p>\n

Google scholar<\/strong>
\nhttps:\/\/scholar.google.com\/citations?user=w9gNODEAAAAJ&hl=en<\/a>
\n[\/et_pb_text][\/et_pb_column][et_pb_column type=”1_4″ _builder_version=”4.16″ custom_padding=”|||” global_colors_info=”{}” custom_padding__hover=”|||”][et_pb_image src=”https:\/\/labs.icahn.mssm.edu\/ableslab\/wp-content\/uploads\/sites\/306\/2019\/07\/Ables.jpg” align=”center” align_tablet=”center” align_phone=”” align_last_edited=”on|desktop” admin_label=”Profile Image” _builder_version=”4.16″ border_radii=”on|3px|3px|3px|3px” global_colors_info=”{}”][\/et_pb_image][et_pb_text _builder_version=”4.16″ global_colors_info=”{}”]Jessica Ables, MD\/PhD<\/strong>
\nAssistant Professor
\nAnnenberg 19-38
\nPhone: 212-241-2774
\njessica.ables@mssm.edu<\/a>
\n[\/et_pb_text][\/et_pb_column][\/et_pb_row][\/et_pb_section][et_pb_section fb_built=”1″ module_id=”funding” module_class=”funding-section” _builder_version=”4.16″ background_color=”#eaf2f7″ global_colors_info=”{}”][et_pb_row _builder_version=”4.16″ global_colors_info=”{}” collapsed=”off”][et_pb_column type=”4_4″ _builder_version=”4.16″ custom_padding=”|||” global_colors_info=”{}” custom_padding__hover=”|||”][et_pb_text admin_label=”Funding and Awards” _builder_version=”4.16″ vertical_offset_tablet=”0″ horizontal_offset_tablet=”0″ z_index_tablet=”0″ text_text_shadow_horizontal_length_tablet=”0px” text_text_shadow_vertical_length_tablet=”0px” text_text_shadow_blur_strength_tablet=”1px” link_text_shadow_horizontal_length_tablet=”0px” link_text_shadow_vertical_length_tablet=”0px” link_text_shadow_blur_strength_tablet=”1px” ul_text_shadow_horizontal_length_tablet=”0px” ul_text_shadow_vertical_length_tablet=”0px” ul_text_shadow_blur_strength_tablet=”1px” ol_text_shadow_horizontal_length_tablet=”0px” ol_text_shadow_vertical_length_tablet=”0px” ol_text_shadow_blur_strength_tablet=”1px” quote_text_shadow_horizontal_length_tablet=”0px” quote_text_shadow_vertical_length_tablet=”0px” quote_text_shadow_blur_strength_tablet=”1px” header_text_shadow_horizontal_length_tablet=”0px” header_text_shadow_vertical_length_tablet=”0px” header_text_shadow_blur_strength_tablet=”1px” header_2_text_shadow_horizontal_length_tablet=”0px” header_2_text_shadow_vertical_length_tablet=”0px” header_2_text_shadow_blur_strength_tablet=”1px” header_3_text_shadow_horizontal_length_tablet=”0px” header_3_text_shadow_vertical_length_tablet=”0px” header_3_text_shadow_blur_strength_tablet=”1px” header_4_text_shadow_horizontal_length_tablet=”0px” header_4_text_shadow_vertical_length_tablet=”0px” header_4_text_shadow_blur_strength_tablet=”1px” header_5_text_shadow_horizontal_length_tablet=”0px” header_5_text_shadow_vertical_length_tablet=”0px” header_5_text_shadow_blur_strength_tablet=”1px” header_6_text_shadow_horizontal_length_tablet=”0px” header_6_text_shadow_vertical_length_tablet=”0px” header_6_text_shadow_blur_strength_tablet=”1px” box_shadow_horizontal_tablet=”0px” box_shadow_vertical_tablet=”0px” box_shadow_blur_tablet=”40px” box_shadow_spread_tablet=”0px” global_colors_info=”{}”]<\/p>\n

Funding and Awards<\/h4>\n

Funding:<\/strong><\/p>\n

\"\"<\/strong><\/p>\n

\"\"<\/p>\n

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NIDA R01DA059455<\/p>\n

\n

Awards:<\/strong><\/p>\n

Jessica Ables receives a Travel Award for the Molecular Psychiatry meeting<\/a>. (November 2023)<\/p>\n

Jessica Ables receives a Travel Award for the annual meeting of the Society for Biological Psychiatry<\/a>. (April 2023)<\/p>\n

Jessica Ables is awarded a Pilot & Feasibility Award from the Einstein-Mount Sinai Diabetes Research Center<\/a>. (September 2022)<\/p>\n

Jessica Ables is awarded a Whitehall Foundation Research Grant<\/a>. (December 2021)<\/p>\n

Jessica Ables is awarded an Alkermes Pathways Research Award<\/a>. (July 2021)<\/p>\n

Jessica Ables is awarded a NARSAD Young Investigator Grant<\/a>. (October 2019)<\/p>\n

Jessica Ables is elected to the Alpha Omega Alpha Honor Society<\/a>. (June 2019)<\/p>\n

Jessica Ables wins Best Poster, 2nd Place, Friedman Brain Institute Neuroscience Retreat. (May 2019)<\/p>\n

Jessica Ables is elected to the Career Development Institute for Psychiatry Class of 2019<\/a>. (January 2019)<\/p>\n

Jessica Ables is named Laughlin Fellow, American College of Psychiatrists<\/a>. (January 2019)<\/p>\n

Jessica Ables is named a Leon Levy Fellow in Neuroscience<\/a>. (April 2018)<\/p>\n

Jessica Ables is named Psychiatry Chief Resident for Research. (2018)<\/p>\n

Jessica Ables receives the NIMH Outstanding Resident Award<\/a>. (July 2017)<\/p>\n

Jessica Ables is named as a Junior Mentor for the Icahn School of Medicine MSTP. (2017)<\/p>\n

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Projects<\/h3>\n

[\/et_pb_text][et_pb_accordion icon_color=”#00aeef” _builder_version=”4.16″ vertical_offset_tablet=”0″ horizontal_offset_tablet=”0″ text_orientation=”left” z_index_tablet=”0″ toggle_text_shadow_horizontal_length_tablet=”0px” toggle_text_shadow_vertical_length_tablet=”0px” toggle_text_shadow_blur_strength_tablet=”1px” closed_toggle_text_shadow_horizontal_length_tablet=”0px” closed_toggle_text_shadow_vertical_length_tablet=”0px” closed_toggle_text_shadow_blur_strength_tablet=”1px” body_text_shadow_horizontal_length_tablet=”0px” body_text_shadow_vertical_length_tablet=”0px” body_text_shadow_blur_strength_tablet=”1px” body_link_text_shadow_horizontal_length_tablet=”0px” body_link_text_shadow_vertical_length_tablet=”0px” body_link_text_shadow_blur_strength_tablet=”1px” body_ul_text_shadow_horizontal_length_tablet=”0px” body_ul_text_shadow_vertical_length_tablet=”0px” body_ul_text_shadow_blur_strength_tablet=”1px” body_ol_text_shadow_horizontal_length_tablet=”0px” body_ol_text_shadow_vertical_length_tablet=”0px” body_ol_text_shadow_blur_strength_tablet=”1px” body_quote_text_shadow_horizontal_length_tablet=”0px” body_quote_text_shadow_vertical_length_tablet=”0px” body_quote_text_shadow_blur_strength_tablet=”1px” border_radii=”on|3px|3px|3px|3px” border_width_all=”0.5px” border_color_all=”#00aeef” box_shadow_horizontal_tablet=”0px” box_shadow_vertical_tablet=”0px” box_shadow_blur_tablet=”40px” box_shadow_spread_tablet=”0px” text_shadow_horizontal_length_tablet=”0px” text_shadow_vertical_length_tablet=”0px” text_shadow_blur_strength_tablet=”1px” global_colors_info=”{}”][et_pb_accordion_item title=”1. Nitric oxide in development of tolerance” open=”on” _builder_version=”4.16″ global_colors_info=”{}”]\"\"<\/p>\n

The interpeduncular nucleus (IPN) is a GABAergic nucleus that is characterized by high expression of neuronal nitric oxide synthase (NOS1) as well as striking vascularity. We have found that NOS1 is increased in IPN after chronic exposure to nicotine, and more recently, to oxycodone. We hypothesize that this increase in NOS1 mediates the development of tolerance to both the aversive and positive effects of drugs. Our goal is to determine if this increase in NOS1 in the IPN generalizes to all other drugs of abuse and might represent a target for the general treatment of addiction. Future studies will focus on visualizing nitric oxide release and the effects of nitric oxide on the epigenome, transcriptome and function of neurons in the reward circuitry.
\n[\/et_pb_accordion_item][et_pb_accordion_item title=”2. Cholinergic vulnerability to hyperglycemia” _builder_version=”4.16″ global_colors_info=”{}” open=”off”]<\/p>\n

\"\"Animal models of diabetes indicate that cholinergic neurons are particularly vulnerable to persistent hyperglycemia and resulting oxidative and nitrosative stress, and we hypothesize that this vulnerability may contribute to the neurocognitive and affective impairments observed in diabetic patients. The medial habenula (MHb) is a highly conserved cholinergic nucleus in the epithalamus that projects to the IPN to regulate levels of serotonin, dopamine and epinephrine and, as a result, mood. The MHb is susceptible to degeneration after repeated administration of drugs of abuse, however, to date no one has examined the effect of persistent hyperglycemia on the functional or structural plasticity of the MHb. Our goal is to understand the molecular, cellular and functional consequences of persistent hyperglycemia on cholinergic neurons in the reward circuitry using cell-type specific epigenomic and transcriptional profiling in combination with viral-mediated gene transfer. We will then relate these changes to behavior.<\/p>\n

\u00a0Check out our recent publication<\/a> examining mitochondrial morphology within the MHb in a mouse model of diabetes.<\/span><\/p>\n

\n

\u00a0And take a look at our collaboration<\/a> with the Sweis lab<\/a> to examine foraging behavior in a mouse model of diabetes.\u00a0<\/p>\n<\/blockquote>\n

 <\/p>\n

[\/et_pb_accordion_item][et_pb_accordion_item title=”3. Axonal transcriptome” title_tablet=”3. Axonal transcriptome” title_phone=”3. Axonal transcriptome” _builder_version=”4.16″ vertical_offset_tablet=”0″ vertical_offset_phone=”0″ horizontal_offset_tablet=”0″ horizontal_offset_phone=”0″ background_color_gradient_direction_tablet=”180deg” background_color_gradient_direction_phone=”180deg” background_color_gradient_stops_tablet=”#2b87da 0%|#29c4a9 100%” background_color_gradient_stops_phone=”#2b87da 0%|#29c4a9 100%” background_color_gradient_start_position_tablet=”0%” background_color_gradient_start_position_phone=”0%” background_color_gradient_end_position_tablet=”100%” background_color_gradient_end_position_phone=”100%” z_index_tablet=”1″ z_index_phone=”1″ hover_transition_duration_tablet=”300ms” hover_transition_duration_phone=”300ms” hover_transition_delay_tablet=”0ms” hover_transition_delay_phone=”0ms” body_text_shadow_horizontal_length_tablet=”0px” body_text_shadow_horizontal_length_phone=”0px” body_text_shadow_vertical_length_tablet=”0px” body_text_shadow_vertical_length_phone=”0px” body_text_shadow_blur_strength_tablet=”1px” body_text_shadow_blur_strength_phone=”1px” body_link_text_shadow_horizontal_length_tablet=”0px” body_link_text_shadow_horizontal_length_phone=”0px” body_link_text_shadow_vertical_length_tablet=”0px” body_link_text_shadow_vertical_length_phone=”0px” body_link_text_shadow_blur_strength_tablet=”1px” body_link_text_shadow_blur_strength_phone=”1px” body_ul_text_shadow_horizontal_length_tablet=”0px” body_ul_text_shadow_horizontal_length_phone=”0px” body_ul_text_shadow_vertical_length_tablet=”0px” body_ul_text_shadow_vertical_length_phone=”0px” body_ul_text_shadow_blur_strength_tablet=”1px” body_ul_text_shadow_blur_strength_phone=”1px” body_ol_text_shadow_horizontal_length_tablet=”0px” body_ol_text_shadow_horizontal_length_phone=”0px” body_ol_text_shadow_vertical_length_tablet=”0px” body_ol_text_shadow_vertical_length_phone=”0px” body_ol_text_shadow_blur_strength_tablet=”1px” body_ol_text_shadow_blur_strength_phone=”1px” body_quote_text_shadow_horizontal_length_tablet=”0px” body_quote_text_shadow_horizontal_length_phone=”0px” body_quote_text_shadow_vertical_length_tablet=”0px” body_quote_text_shadow_vertical_length_phone=”0px” body_quote_text_shadow_blur_strength_tablet=”1px” body_quote_text_shadow_blur_strength_phone=”1px” box_shadow_horizontal_tablet=”0px” box_shadow_horizontal_phone=”0px” box_shadow_vertical_tablet=”0px” box_shadow_vertical_phone=”0px” box_shadow_blur_tablet=”40px” box_shadow_blur_phone=”40px” box_shadow_spread_tablet=”0px” box_shadow_spread_phone=”0px” text_shadow_horizontal_length_tablet=”0em” text_shadow_horizontal_length_phone=”0em” text_shadow_vertical_length_tablet=”0em” text_shadow_vertical_length_phone=”0em” text_shadow_blur_strength_tablet=”0em” text_shadow_blur_strength_phone=”0em” global_colors_info=”{}” toggle_text_shadow_horizontal_length_tablet=”0px” toggle_text_shadow_horizontal_length_phone=”0px” toggle_text_shadow_vertical_length_tablet=”0px” toggle_text_shadow_vertical_length_phone=”0px” toggle_text_shadow_blur_strength_tablet=”1px” toggle_text_shadow_blur_strength_phone=”1px” closed_toggle_text_shadow_horizontal_length_tablet=”0px” closed_toggle_text_shadow_horizontal_length_phone=”0px” closed_toggle_text_shadow_vertical_length_tablet=”0px” closed_toggle_text_shadow_vertical_length_phone=”0px” closed_toggle_text_shadow_blur_strength_tablet=”1px” closed_toggle_text_shadow_blur_strength_phone=”1px” open=”off”]\"\"Recent research has revealed that neuronal axons have specialized mechanisms to regulate delivery and utilization of mRNAs independently of the neuronal cell body, where the nucleus resides. This is not surprising given that in many cases (e.g. motor neurons in the limbs), the axons are far removed from the cell body and require the ability to respond to stimuli on timescales that would prohibit gene expression from the nucleus and subsequent delivery to the distal axon. Projection neurons in the brain provide a unique opportunity to profile the transcripts that are utilized in discrete compartments of the cell, as the axons are physically separate from the cell body. Our lab is currently profiling axonal transcriptomes in specific cell populations in the normal mouse brain during fear learning. Our goal is to determine how translation is locally regulated in response to various stimuli, including stress and metabolic derangements.
\n[\/et_pb_accordion_item][\/et_pb_accordion][\/et_pb_column][\/et_pb_row][\/et_pb_section][et_pb_section fb_built=”1″ module_id=”team” module_class=”team-section” _builder_version=”4.16″ background_color=”#ffffff” global_colors_info=”{}”][et_pb_row admin_label=”team” _builder_version=”4.16″ custom_margin=”||-50px|” global_colors_info=”{}”][et_pb_column type=”4_4″ _builder_version=”4.16″ custom_padding=”|||” global_colors_info=”{}” custom_padding__hover=”|||”][et_pb_text admin_label=”team” _builder_version=”4.16″ global_colors_info=”{}”]<\/p>\n

Current Team<\/h3>\n

[\/et_pb_text][\/et_pb_column][\/et_pb_row][et_pb_row column_structure=”1_3,1_3,1_3″ _builder_version=”4.16″ global_colors_info=”{}”][et_pb_column type=”1_3″ _builder_version=”4.16″ custom_padding=”|||” global_colors_info=”{}” custom_padding__hover=”|||”][et_pb_image src=”https:\/\/labs.icahn.mssm.edu\/ableslab\/wp-content\/uploads\/sites\/306\/2019\/07\/Jess-headshot3.jpg” align_tablet=”center” align_phone=”” align_last_edited=”on|desktop” _builder_version=”4.16″ border_radii=”on|4px|4px|4px|4px” global_colors_info=”{}”][\/et_pb_image][et_pb_text admin_label=”Mount Sinai” _builder_version=”4.16″ global_colors_info=”{}”]<\/p>\n

Jessica Ables, MD\/PhD<\/strong>
Assistant Professor
jessica.ables@mssm.edu<\/a><\/p>\n

[\/et_pb_text][et_pb_image src=”https:\/\/labs.icahn.mssm.edu\/ableslab\/wp-content\/uploads\/sites\/306\/2021\/09\/Sam-Brown-scaled.jpg” align_tablet=”center” align_phone=”” align_last_edited=”on|desktop” _builder_version=”4.16″ vertical_offset_tablet=”0″ horizontal_offset_tablet=”0″ max_width=”70%” z_index_tablet=”0″ border_color_all=”#ffffff” box_shadow_horizontal_tablet=”0px” box_shadow_vertical_tablet=”0px” box_shadow_blur_tablet=”40px” box_shadow_spread_tablet=”0px” global_colors_info=”{}”][\/et_pb_image][et_pb_text admin_label=”Mount Sinai” _builder_version=”4.16″ vertical_offset_tablet=”0″ horizontal_offset_tablet=”0″ z_index_tablet=”0″ text_text_shadow_horizontal_length_tablet=”0px” text_text_shadow_vertical_length_tablet=”0px” text_text_shadow_blur_strength_tablet=”1px” link_text_shadow_horizontal_length_tablet=”0px” link_text_shadow_vertical_length_tablet=”0px” link_text_shadow_blur_strength_tablet=”1px” ul_text_shadow_horizontal_length_tablet=”0px” ul_text_shadow_vertical_length_tablet=”0px” ul_text_shadow_blur_strength_tablet=”1px” ol_text_shadow_horizontal_length_tablet=”0px” ol_text_shadow_vertical_length_tablet=”0px” ol_text_shadow_blur_strength_tablet=”1px” quote_text_shadow_horizontal_length_tablet=”0px” quote_text_shadow_vertical_length_tablet=”0px” quote_text_shadow_blur_strength_tablet=”1px” header_text_shadow_horizontal_length_tablet=”0px” header_text_shadow_vertical_length_tablet=”0px” header_text_shadow_blur_strength_tablet=”1px” header_2_text_shadow_horizontal_length_tablet=”0px” header_2_text_shadow_vertical_length_tablet=”0px” header_2_text_shadow_blur_strength_tablet=”1px” header_3_text_shadow_horizontal_length_tablet=”0px” header_3_text_shadow_vertical_length_tablet=”0px” header_3_text_shadow_blur_strength_tablet=”1px” header_4_text_shadow_horizontal_length_tablet=”0px” header_4_text_shadow_vertical_length_tablet=”0px” header_4_text_shadow_blur_strength_tablet=”1px” header_5_text_shadow_horizontal_length_tablet=”0px” header_5_text_shadow_vertical_length_tablet=”0px” header_5_text_shadow_blur_strength_tablet=”1px” header_6_text_shadow_horizontal_length_tablet=”0px” header_6_text_shadow_vertical_length_tablet=”0px” header_6_text_shadow_blur_strength_tablet=”1px” box_shadow_horizontal_tablet=”0px” box_shadow_vertical_tablet=”0px” box_shadow_blur_tablet=”40px” box_shadow_spread_tablet=”0px” global_colors_info=”{}”]Samantha Brown<\/strong>
\nMD\/PhD Student (2021-)
\nsamantha.brown@icahn.mssm.edu<\/a>
\n[\/et_pb_text][et_pb_image src=”https:\/\/labs.icahn.mssm.edu\/ableslab\/wp-content\/uploads\/sites\/306\/2025\/03\/Ables-Eftychia.png” title_text=”Ables-Eftychia” _builder_version=”4.16″ _module_preset=”default” global_colors_info=”{}”][\/et_pb_image][et_pb_text _builder_version=”4.16″ _module_preset=”default” global_colors_info=”{}”]<\/p>\n

Eftychia Markopoulou
<\/strong>Research Associate (2025-)
eftychia.markopoulou@mssm.edu<\/p>\n

[\/et_pb_text][\/et_pb_column][et_pb_column type=”1_3″ _builder_version=”4.16″ custom_padding=”|||” global_colors_info=”{}” custom_padding__hover=”|||”][et_pb_image src=”https:\/\/labs.icahn.mssm.edu\/ableslab\/wp-content\/uploads\/sites\/306\/2021\/09\/Mo-Jodieri.jpg” align_tablet=”center” align_phone=”” align_last_edited=”on|desktop” _builder_version=”4.16″ vertical_offset_tablet=”0″ horizontal_offset_tablet=”0″ max_width=”70%” z_index_tablet=”0″ border_color_all=”#ffffff” box_shadow_horizontal_tablet=”0px” box_shadow_vertical_tablet=”0px” box_shadow_blur_tablet=”40px” box_shadow_spread_tablet=”0px” global_colors_info=”{}”][\/et_pb_image][et_pb_text admin_label=”Mount Sinai” _builder_version=”4.16″ vertical_offset_tablet=”0″ horizontal_offset_tablet=”0″ z_index_tablet=”0″ text_text_shadow_horizontal_length_tablet=”0px” text_text_shadow_vertical_length_tablet=”0px” text_text_shadow_blur_strength_tablet=”1px” link_text_shadow_horizontal_length_tablet=”0px” link_text_shadow_vertical_length_tablet=”0px” link_text_shadow_blur_strength_tablet=”1px” ul_text_shadow_horizontal_length_tablet=”0px” ul_text_shadow_vertical_length_tablet=”0px” ul_text_shadow_blur_strength_tablet=”1px” ol_text_shadow_horizontal_length_tablet=”0px” ol_text_shadow_vertical_length_tablet=”0px” ol_text_shadow_blur_strength_tablet=”1px” quote_text_shadow_horizontal_length_tablet=”0px” quote_text_shadow_vertical_length_tablet=”0px” quote_text_shadow_blur_strength_tablet=”1px” header_text_shadow_horizontal_length_tablet=”0px” header_text_shadow_vertical_length_tablet=”0px” header_text_shadow_blur_strength_tablet=”1px” header_2_text_shadow_horizontal_length_tablet=”0px” header_2_text_shadow_vertical_length_tablet=”0px” header_2_text_shadow_blur_strength_tablet=”1px” header_3_text_shadow_horizontal_length_tablet=”0px” header_3_text_shadow_vertical_length_tablet=”0px” header_3_text_shadow_blur_strength_tablet=”1px” header_4_text_shadow_horizontal_length_tablet=”0px” header_4_text_shadow_vertical_length_tablet=”0px” header_4_text_shadow_blur_strength_tablet=”1px” header_5_text_shadow_horizontal_length_tablet=”0px” header_5_text_shadow_vertical_length_tablet=”0px” header_5_text_shadow_blur_strength_tablet=”1px” header_6_text_shadow_horizontal_length_tablet=”0px” header_6_text_shadow_vertical_length_tablet=”0px” header_6_text_shadow_blur_strength_tablet=”1px” box_shadow_horizontal_tablet=”0px” box_shadow_vertical_tablet=”0px” box_shadow_blur_tablet=”40px” box_shadow_spread_tablet=”0px” global_colors_info=”{}”]<\/p>\n

Mohammad Jodeiri Farshbaf, PhD<\/strong>
Postdoctoral Researcher (2021-)
mohammad.jodeirifarshbaf@mssm.edu<\/a><\/p>\n

[\/et_pb_text][et_pb_image src=”https:\/\/labs.icahn.mssm.edu\/ableslab\/wp-content\/uploads\/sites\/306\/2022\/10\/Sep-20-2021WTC2031-e1741193102136.jpg” title_text=”Sep 20 2021WTC2031″ _builder_version=”4.16″ _module_preset=”default” global_colors_info=”{}”][\/et_pb_image][et_pb_text admin_label=”Mount Sinai” _builder_version=”4.16″ vertical_offset_tablet=”0″ horizontal_offset_tablet=”0″ z_index_tablet=”0″ text_text_shadow_horizontal_length_tablet=”0px” text_text_shadow_vertical_length_tablet=”0px” text_text_shadow_blur_strength_tablet=”1px” link_text_shadow_horizontal_length_tablet=”0px” link_text_shadow_vertical_length_tablet=”0px” link_text_shadow_blur_strength_tablet=”1px” ul_text_shadow_horizontal_length_tablet=”0px” ul_text_shadow_vertical_length_tablet=”0px” ul_text_shadow_blur_strength_tablet=”1px” ol_text_shadow_horizontal_length_tablet=”0px” ol_text_shadow_vertical_length_tablet=”0px” ol_text_shadow_blur_strength_tablet=”1px” quote_text_shadow_horizontal_length_tablet=”0px” quote_text_shadow_vertical_length_tablet=”0px” quote_text_shadow_blur_strength_tablet=”1px” header_text_shadow_horizontal_length_tablet=”0px” header_text_shadow_vertical_length_tablet=”0px” header_text_shadow_blur_strength_tablet=”1px” header_2_text_shadow_horizontal_length_tablet=”0px” header_2_text_shadow_vertical_length_tablet=”0px” header_2_text_shadow_blur_strength_tablet=”1px” header_3_text_shadow_horizontal_length_tablet=”0px” header_3_text_shadow_vertical_length_tablet=”0px” header_3_text_shadow_blur_strength_tablet=”1px” header_4_text_shadow_horizontal_length_tablet=”0px” header_4_text_shadow_vertical_length_tablet=”0px” header_4_text_shadow_blur_strength_tablet=”1px” header_5_text_shadow_horizontal_length_tablet=”0px” header_5_text_shadow_vertical_length_tablet=”0px” header_5_text_shadow_blur_strength_tablet=”1px” header_6_text_shadow_horizontal_length_tablet=”0px” header_6_text_shadow_vertical_length_tablet=”0px” header_6_text_shadow_blur_strength_tablet=”1px” box_shadow_horizontal_tablet=”0px” box_shadow_vertical_tablet=”0px” box_shadow_blur_tablet=”40px” box_shadow_spread_tablet=”0px” global_colors_info=”{}”]Adriana Mendez
\n<\/strong>Neuroscience PhD Student (2022-)
\nadriana.mendez@icahn.mssm.edu<\/a>
\n[\/et_pb_text][et_pb_image src=”https:\/\/labs.icahn.mssm.edu\/ableslab\/wp-content\/uploads\/sites\/306\/2025\/03\/Ables-Mariam.png” title_text=”Ables-Mariam” align=”center” admin_label=”Eftychia” _builder_version=”4.16″ _module_preset=”default” border_radii=”on|6px|6px|6px|6px” global_colors_info=”{}”][\/et_pb_image][et_pb_text _builder_version=”4.16″ _module_preset=”default” global_colors_info=”{}”]<\/p>\n

Mariam Mahboob<\/strong>
Neuroscience PhD student
mariam.mahboob@icahn.mssm.edu<\/a><\/p>\n

[\/et_pb_text][\/et_pb_column][et_pb_column type=”1_3″ _builder_version=”4.16″ custom_padding=”|||” global_colors_info=”{}” custom_padding__hover=”|||”][et_pb_image src=”https:\/\/labs.icahn.mssm.edu\/ableslab\/wp-content\/uploads\/sites\/306\/2025\/03\/Nrice.jpg” title_text=”Nrice” align_tablet=”center” align_phone=”” align_last_edited=”on|desktop” _builder_version=”4.16″ max_width=”70%” border_color_all=”#ffffff” global_colors_info=”{}”][\/et_pb_image][et_pb_text admin_label=”Mount Sinai” _builder_version=”4.16″ vertical_offset_tablet=”0″ horizontal_offset_tablet=”0″ z_index_tablet=”0″ text_text_shadow_horizontal_length_tablet=”0px” text_text_shadow_vertical_length_tablet=”0px” text_text_shadow_blur_strength_tablet=”1px” link_text_shadow_horizontal_length_tablet=”0px” link_text_shadow_vertical_length_tablet=”0px” link_text_shadow_blur_strength_tablet=”1px” ul_text_shadow_horizontal_length_tablet=”0px” ul_text_shadow_vertical_length_tablet=”0px” ul_text_shadow_blur_strength_tablet=”1px” ol_text_shadow_horizontal_length_tablet=”0px” ol_text_shadow_vertical_length_tablet=”0px” ol_text_shadow_blur_strength_tablet=”1px” quote_text_shadow_horizontal_length_tablet=”0px” quote_text_shadow_vertical_length_tablet=”0px” quote_text_shadow_blur_strength_tablet=”1px” header_text_shadow_horizontal_length_tablet=”0px” header_text_shadow_vertical_length_tablet=”0px” header_text_shadow_blur_strength_tablet=”1px” header_2_text_shadow_horizontal_length_tablet=”0px” header_2_text_shadow_vertical_length_tablet=”0px” header_2_text_shadow_blur_strength_tablet=”1px” header_3_text_shadow_horizontal_length_tablet=”0px” header_3_text_shadow_vertical_length_tablet=”0px” header_3_text_shadow_blur_strength_tablet=”1px” header_4_text_shadow_horizontal_length_tablet=”0px” header_4_text_shadow_vertical_length_tablet=”0px” header_4_text_shadow_blur_strength_tablet=”1px” header_5_text_shadow_horizontal_length_tablet=”0px” header_5_text_shadow_vertical_length_tablet=”0px” header_5_text_shadow_blur_strength_tablet=”1px” header_6_text_shadow_horizontal_length_tablet=”0px” header_6_text_shadow_vertical_length_tablet=”0px” header_6_text_shadow_blur_strength_tablet=”1px” box_shadow_horizontal_tablet=”0px” box_shadow_vertical_tablet=”0px” box_shadow_blur_tablet=”40px” box_shadow_spread_tablet=”0px” global_colors_info=”{}”]<\/p>\n

Natasha Rice<\/strong>
Master’s Student (2023-)
natasha.rice@icahn.mssm.edu<\/a><\/p>\n

[\/et_pb_text][et_pb_image src=”https:\/\/labs.icahn.mssm.edu\/ableslab\/wp-content\/uploads\/sites\/306\/2025\/03\/TMatos.jpg” title_text=”TMatos” _builder_version=”4.16″ _module_preset=”default” global_colors_info=”{}”][\/et_pb_image][et_pb_text _builder_version=”4.16″ _module_preset=”default” global_colors_info=”{}”]<\/p>\n

Taelor Matos<\/strong>
PREP Student (2023-)
taelor.matos@icahn.mssm.edu<\/a><\/p>\n

[\/et_pb_text][et_pb_text admin_label=”Mount Sinai” _builder_version=”4.16″ global_colors_info=”{}”] 
\n[\/et_pb_text][\/et_pb_column][\/et_pb_row][et_pb_row column_structure=”4_4,1_4″ admin_label=”team” _builder_version=”4.16″ custom_margin=”||-50px|” global_colors_info=”{}”][et_pb_column type=”4_4″ _builder_version=”4.16″ custom_padding=”|||” global_colors_info=”{}” custom_padding__hover=”|||”][et_pb_text admin_label=”team” _builder_version=”4.16″ global_colors_info=”{}”]<\/p>\n

Current Volunteers<\/span><\/p>\n

Jake Tetenman – Washington University at St. Louis<\/p>\n

Zim Khan – McNair Scholar, Hunter College, CUNY<\/p>\n

Hridika Tasnim – McNair Scholar, Hunter College, CUNY<\/p>\n

[\/et_pb_text][\/et_pb_column][et_pb_column type=”1_4″ _builder_version=”4.16″ custom_padding=”|||” global_colors_info=”{}” custom_padding__hover=”|||”][\/et_pb_column][\/et_pb_row][et_pb_row admin_label=”team” _builder_version=”4.16″ custom_margin=”||-50px|” global_colors_info=”{}”][et_pb_column type=”4_4″ _builder_version=”4.16″ custom_padding=”|||” global_colors_info=”{}” custom_padding__hover=”|||”][et_pb_text admin_label=”team” _builder_version=”4.16″ global_colors_info=”{}”]<\/p>\n

Former Members<\/h3>\n

[\/et_pb_text][\/et_pb_column][\/et_pb_row][et_pb_row column_structure=”1_5,1_5,1_5,1_5,1_5″ _builder_version=”4.16″ collapsed=”off” global_colors_info=”{}”][et_pb_column type=”1_5″ _builder_version=”4.16″ custom_padding=”|||” global_colors_info=”{}” custom_padding__hover=”|||”][et_pb_image src=”https:\/\/labs.icahn.mssm.edu\/ableslab\/wp-content\/uploads\/sites\/306\/2019\/07\/Zainab-NSM_0009-2.jpg” align_tablet=”center” align_phone=”” align_last_edited=”on|desktop” _builder_version=”4.16″ border_radii=”on|4px|4px|4px|4px” global_colors_info=”{}”][\/et_pb_image][et_pb_text admin_label=”Mount Sinai” _builder_version=”4.16″ global_colors_info=”{}”]Zainab Oketokoun<\/strong>
\nAssociate Researcher (2018-2022)
\n[\/et_pb_text][\/et_pb_column][et_pb_column type=”1_5″ _builder_version=”4.16″ custom_padding=”|||” global_colors_info=”{}” custom_padding__hover=”|||”][et_pb_image src=”https:\/\/labs.icahn.mssm.edu\/ableslab\/wp-content\/uploads\/sites\/306\/2022\/10\/Chino1.jpg” title_text=”Chino1″ _builder_version=”4.16″ _module_preset=”default” global_colors_info=”{}”][\/et_pb_image][et_pb_text admin_label=”Mount Sinai” _builder_version=”4.16″ global_colors_info=”{}”]Chino Nwakama<\/strong>
\nUniversity of Minnesota – SURP4US<\/a> Student (2022) – Now an MSTP student at Icahn School of Medicine at Mount Sinai
\n[\/et_pb_text][\/et_pb_column][et_pb_column type=”1_5″ _builder_version=”4.16″ custom_padding=”|||” global_colors_info=”{}” custom_padding__hover=”|||”][et_pb_image src=”https:\/\/labs.icahn.mssm.edu\/ableslab\/wp-content\/uploads\/sites\/306\/2022\/10\/2023_haller.jpg” title_text=”2023_haller” _builder_version=”4.16″ _module_preset=”default” global_colors_info=”{}”][\/et_pb_image][et_pb_text admin_label=”Mount Sinai” _builder_version=”4.16″ global_colors_info=”{}”]<\/p>\n

Jillian Haller<\/strong>
Scranton University – Undergraduate Volunteer (2022)<\/p>\n

[\/et_pb_text][\/et_pb_column][et_pb_column type=”1_5″ _builder_version=”4.16″ _module_preset=”default” global_colors_info=”{}”][et_pb_image src=”https:\/\/labs.icahn.mssm.edu\/ableslab\/wp-content\/uploads\/sites\/306\/2020\/11\/headshotfinalKN-e1741192437879.jpg” title_text=”headshotfinalKN” _builder_version=”4.16″ _module_preset=”default” global_colors_info=”{}”][\/et_pb_image][et_pb_text _builder_version=”4.16″ _module_preset=”default” global_colors_info=”{}”]<\/p>\n

Krist Niblo<\/strong>
Master’s Student – (2020-2023)<\/p>\n

[\/et_pb_text][\/et_pb_column][et_pb_column type=”1_5″ _builder_version=”4.16″ custom_padding=”|||” global_colors_info=”{}” custom_padding__hover=”|||”][\/et_pb_column][\/et_pb_row][et_pb_row column_structure=”4_4,1_4″ admin_label=”team” _builder_version=”4.16″ custom_margin=”||-50px|” global_colors_info=”{}”][et_pb_column type=”4_4″ _builder_version=”4.16″ custom_padding=”|||” global_colors_info=”{}” custom_padding__hover=”|||”][et_pb_text admin_label=”team” _builder_version=”4.16″ global_colors_info=”{}”]<\/p>\n

Former Volunteers<\/h3>\n

Gabby Chavez (2018-2023) – Pelham Memorial High School & Fordham University<\/p>\n

Martha Solomon (2019) – SUNY Downstate Medical Student<\/p>\n

Nazeen Shah (2021-2022) -Spackenkill High School<\/p>\n

Almer Yu (2022) – Hunter College High School<\/p>\n

Yacoub Alokam – St. Francis College Undergraduate<\/p>\n

Sophia Leng – Hunter College High School<\/p>\n

Alp Vargelci – Stuyvesant High School<\/p>\n

Natalia Zheng – Stuyvesant High School<\/p>\n

Namrata Marjit, MS – Icahn School of Medicine<\/p>\n

Stella Lodewick – Clemson University
\n[\/et_pb_text][\/et_pb_column][et_pb_column type=”1_4″ _builder_version=”4.16″ custom_padding=”|||” global_colors_info=”{}” custom_padding__hover=”|||”][\/et_pb_column][\/et_pb_row][et_pb_row column_structure=”4_4,1_4″ admin_label=”team” _builder_version=”4.16″ custom_margin=”||-50px|” global_colors_info=”{}”][et_pb_column type=”4_4″ _builder_version=”4.16″ custom_padding=”|||” global_colors_info=”{}” custom_padding__hover=”|||”][et_pb_text admin_label=”team” _builder_version=”4.16″ global_colors_info=”{}”][\/et_pb_text][\/et_pb_column][et_pb_column type=”1_4″ _builder_version=”4.16″ custom_padding=”|||” global_colors_info=”{}” custom_padding__hover=”|||”][\/et_pb_column][\/et_pb_row][\/et_pb_section][et_pb_section fb_built=”1″ module_id=”positions” module_class=”positions-section” _builder_version=”4.16″ custom_margin=”||5em|” global_colors_info=”{}”][et_pb_row admin_label=”team” _builder_version=”4.16″ custom_margin=”||-50px|” global_colors_info=”{}”][et_pb_column type=”4_4″ _builder_version=”4.16″ custom_padding=”|||” global_colors_info=”{}” custom_padding__hover=”|||”][et_pb_divider divider_style=”dotted” divider_position=”center” divider_weight=”0.5″ _builder_version=”4.16″ height=”25px” custom_margin=”-5em||2em|” global_colors_info=”{}”][\/et_pb_divider][et_pb_text admin_label=”Postitions” _builder_version=”4.16″ global_colors_info=”{}”]<\/p>\n

Potential Lab Members<\/h3>\n

Icahn School of Medicine at Mount Sinai is seeking enthusiastic, detail-oriented applicants. The School is one of the nation\u2019s leading medical schools, ranked in the top 20 schools for NIH funding. Both the Psychiatry and Neuroscience Departments offer an outstanding intellectual and multidisciplinary research environment with a commitment to translational research. Note that we do not offer observerships for foreign medical graduates.<\/strong><\/p>\n

Volunteers:\u00a0<\/strong>
\nWe typically accept 1-2 high school and 1-2 undergraduate volunteers each year, with the majority of the time in the lab spent during the summer. Volunteers are expected to work independently with supervision after training. Interested candidates should send their resume\/CV in January<\/strong> for a summer position.<\/p>\n

Graduate Students:<\/strong>
\nAll graduate students interested in our lab must first apply and be accepted into a program at Mount Sinai.<\/a><\/p>\n

Postdoctoral Fellows:<\/strong>
\nPostdoctoral candidates should have a Ph.D. and\/or M.D. and a strong basic science<\/strong> background in molecular\/cellular neuroscience.\u00a0Those with experience in the following fields are particularly encouraged to apply: computational approaches for analysis of sequencing datasets, machine learning approaches for animal behavior, electrophysiology, fiber photometry or in vivo imaging.<\/p>\n

Interested candidates should submit their Curriculum Vitae and contact information for at least three professional references to Jessica.ables@mssm.edu.
\n[\/et_pb_text][\/et_pb_column][\/et_pb_row][\/et_pb_section][et_pb_section fb_built=”1″ _builder_version=”4.16″ background_color=”#000000″ border_width_all=”0.5px” border_color_bottom=”#00aeef” global_colors_info=”{}”][et_pb_row column_structure=”1_4,1_4,1_4,1_4″ _builder_version=”4.16″ background_size=”initial” background_position=”top_left” background_repeat=”repeat” global_colors_info=”{}”][et_pb_column type=”1_4″ _builder_version=”4.16″ custom_padding=”|||” global_colors_info=”{}” custom_padding__hover=”|||”][et_pb_text _builder_version=”4.16″ text_text_color=”#ffffff” global_colors_info=”{}”]Location<\/strong>
\nANNENBERG BUILDING 19-38
\nIcahn School of Medicine at Mount Sinai
\n1 Gustave L. Levy Pl, New York, NY 10029
\n[\/et_pb_text][\/et_pb_column][et_pb_column type=”1_4″ _builder_version=”4.16″ custom_padding=”|||” global_colors_info=”{}” custom_padding__hover=”|||”][\/et_pb_column][et_pb_column type=”1_4″ _builder_version=”4.16″ custom_padding=”|||” global_colors_info=”{}” custom_padding__hover=”|||”][\/et_pb_column][et_pb_column type=”1_4″ _builder_version=”4.16″ custom_padding=”|||” global_colors_info=”{}” custom_padding__hover=”|||”][\/et_pb_column][\/et_pb_row][\/et_pb_section]<\/p>\n","protected":false},"excerpt":{"rendered":"

Research The goal of our research is to better understand the effects of chronic metabolic diseases, such as diabetes, on brain function. People with diabetes have double the rate of mental illness compared to those who don’t have diabetes and are twice as likely to not respond to current treatments. Currently, we use mouse models […]<\/p>\n","protected":false},"author":337,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_et_pb_use_builder":"on","_et_pb_old_content":"[et_pb_section fb_built=\"1\" fullwidth=\"on\" disabled_on=\"on|on|on\" _builder_version=\"3.22\" disabled=\"on\"][et_pb_fullwidth_menu menu_id=\"5\" submenu_direction=\"downwards\" fullwidth_menu=\"off\" _builder_version=\"3.19.10\"][\/et_pb_fullwidth_menu][\/et_pb_section][et_pb_section fb_built=\"1\" fullwidth=\"on\" _builder_version=\"3.22\" background_color=\"#000000\"][et_pb_fullwidth_slider show_pagination=\"off\" _builder_version=\"3.19.10\" animation_style=\"slide\" animation_direction=\"right\" auto=\"on\"][et_pb_slide heading=\"Ables Laboratory\" use_bg_overlay=\"off\" use_text_overlay=\"off\" _builder_version=\"3.19.10\" use_background_color_gradient=\"on\" background_image=\"https:\/\/labs.icahn.mssm.edu\/ableslab\/wp-content\/uploads\/sites\/306\/2019\/07\/amigo1-gfp-sst-nos1-ipn.jpg\" button_on_hover=\"on\" sticky_transition=\"on\"][\/et_pb_slide][et_pb_slide heading=\"Lab of Metabolic Psychiatry\" use_bg_overlay=\"off\" use_text_overlay=\"off\" _builder_version=\"3.19.10\" use_background_color_gradient=\"on\" background_image=\"https:\/\/labs.icahn.mssm.edu\/ableslab\/wp-content\/uploads\/sites\/306\/2019\/07\/epyc-gfp-amigo1-mcherry-nos1-ipn.jpg\" button_on_hover=\"on\" sticky_transition=\"on\"][\/et_pb_slide][\/et_pb_fullwidth_slider][\/et_pb_section][et_pb_section fb_built=\"1\" module_id=\"research\" module_class=\"research-section\" _builder_version=\"3.22\"][et_pb_row column_structure=\"3_4,1_4\" _builder_version=\"3.25\" background_size=\"initial\" background_position=\"top_left\" background_repeat=\"repeat\"][et_pb_column type=\"3_4\" _builder_version=\"3.0.47\" custom_padding=\"|||\" custom_padding__hover=\"|||\"][et_pb_text admin_label=\"research\" _builder_version=\"3.27.4\"]\r\n

Research<\/h3>\r\n

The goal of our research is to better understand the effects of chronic metabolic diseases, such as diabetes, on brain function. People with diabetes have double the rate of mental illness compared to those who don't have diabetes and are twice as likely to not respond to current treatments. Currently, we use mouse models of diabetes to identify the ways in which chronic hyperglycemia can lead to behaviors associated with mental illness by exploring processes at the behavioral, circuit, cellular and molecular levels.\u00a0 A major focus of our work is on hyperglycemia-induced changes in gene expression within cholinergic neurons in the brain\u2019s reward circuitry. We also use operant models to explore how diabetes affects learning and response to rewards.\u00a0 In the near future, we plan to repeat many of these behavioral studies in people with diabetes or at risk of developing diabetes.<\/p>\r\nPubMed publications<\/strong>\r\nhttps:\/\/www.ncbi.nlm.nih.gov\/pubmed\/?term=ables+jl<\/a>\r\n\r\nGoogle scholar<\/strong>\r\nhttps:\/\/scholar.google.com\/citations?user=w9gNODEAAAAJ&hl=en<\/a>\r\n\r\n[\/et_pb_text][\/et_pb_column][et_pb_column type=\"1_4\" _builder_version=\"3.0.47\" custom_padding=\"|||\" custom_padding__hover=\"|||\"][et_pb_image src=\"https:\/\/labs.icahn.mssm.edu\/ableslab\/wp-content\/uploads\/sites\/306\/2019\/07\/Ables.jpg\" align=\"center\" align_tablet=\"center\" align_phone=\"\" align_last_edited=\"on|desktop\" admin_label=\"Profile Image\" _builder_version=\"3.23\" border_radii=\"on|3px|3px|3px|3px\"][\/et_pb_image][et_pb_text _builder_version=\"3.27.4\"]\r\n\r\nJessica Ables, MD\/PhD<\/strong>\r\nAssistant Professor\r\nAnnenberg 19-38\r\nPhone: 212-241-2774\r\njessica.ables@mssm.edu<\/a>\r\n\r\n[\/et_pb_text][\/et_pb_column][\/et_pb_row][\/et_pb_section][et_pb_section fb_built=\"1\" module_id=\"funding\" module_class=\"funding-section\" _builder_version=\"3.22\" background_color=\"#eaf2f7\"][et_pb_row _builder_version=\"3.25\"][et_pb_column type=\"4_4\" _builder_version=\"3.0.47\" custom_padding=\"|||\" custom_padding__hover=\"|||\"][et_pb_text admin_label=\"Funding and Awards\" _builder_version=\"4.9.0\" vertical_offset_tablet=\"0\" horizontal_offset_tablet=\"0\" hover_enabled=\"0\" z_index_tablet=\"0\" text_text_shadow_horizontal_length_tablet=\"0px\" text_text_shadow_vertical_length_tablet=\"0px\" text_text_shadow_blur_strength_tablet=\"1px\" link_text_shadow_horizontal_length_tablet=\"0px\" link_text_shadow_vertical_length_tablet=\"0px\" link_text_shadow_blur_strength_tablet=\"1px\" ul_text_shadow_horizontal_length_tablet=\"0px\" ul_text_shadow_vertical_length_tablet=\"0px\" ul_text_shadow_blur_strength_tablet=\"1px\" ol_text_shadow_horizontal_length_tablet=\"0px\" ol_text_shadow_vertical_length_tablet=\"0px\" ol_text_shadow_blur_strength_tablet=\"1px\" quote_text_shadow_horizontal_length_tablet=\"0px\" quote_text_shadow_vertical_length_tablet=\"0px\" quote_text_shadow_blur_strength_tablet=\"1px\" header_text_shadow_horizontal_length_tablet=\"0px\" header_text_shadow_vertical_length_tablet=\"0px\" header_text_shadow_blur_strength_tablet=\"1px\" header_2_text_shadow_horizontal_length_tablet=\"0px\" header_2_text_shadow_vertical_length_tablet=\"0px\" header_2_text_shadow_blur_strength_tablet=\"1px\" header_3_text_shadow_horizontal_length_tablet=\"0px\" header_3_text_shadow_vertical_length_tablet=\"0px\" header_3_text_shadow_blur_strength_tablet=\"1px\" header_4_text_shadow_horizontal_length_tablet=\"0px\" header_4_text_shadow_vertical_length_tablet=\"0px\" header_4_text_shadow_blur_strength_tablet=\"1px\" header_5_text_shadow_horizontal_length_tablet=\"0px\" header_5_text_shadow_vertical_length_tablet=\"0px\" header_5_text_shadow_blur_strength_tablet=\"1px\" header_6_text_shadow_horizontal_length_tablet=\"0px\" header_6_text_shadow_vertical_length_tablet=\"0px\" header_6_text_shadow_blur_strength_tablet=\"1px\" box_shadow_horizontal_tablet=\"0px\" box_shadow_vertical_tablet=\"0px\" box_shadow_blur_tablet=\"40px\" box_shadow_spread_tablet=\"0px\" sticky_enabled=\"0\"]\r\n

Funding and Awards<\/h4>\r\nFunding:<\/strong>\r\n\r\n\"\"<\/strong>\r\n\r\n\"\"\r\n\r\n\"\"\r\n\r\n\"\"\r\n\r\n\"\"\r\n\r\nAwards:<\/strong>\r\n\r\nJessica Ables receives a Travel Award for the Molecular Psychiatry meeting<\/a>. (November 2023)\r\n\r\nJessica Ables receives a Travel Award for the annual meeting of the Society for Biological Psychiatry<\/a>. (April 2023)\r\n\r\nJessica Ables is awarded a Pilot & Feasibility Award from the Einstein-Mount Sinai Diabetes Research Center<\/a>. (September 2022)\r\n\r\nJessica Ables is awarded a Whitehall Foundation Research Grant<\/a>. (December 2021)\r\n\r\nJessica Ables is awarded an Alkermes Pathways Research Award<\/a>. (July 2021)\r\n\r\nJessica Ables is awarded a NARSAD Young Investigator Grant<\/a>. (October 2019)\r\n\r\nJessica Ables is elected to the Alpha Omega Alpha Honor Society<\/a>. (June 2019)\r\n\r\nJessica Ables wins Best Poster, 2nd Place, Friedman Brain Institute Neuroscience Retreat. (May 2019)\r\n\r\nJessica Ables is elected to the Career Development Institute for Psychiatry Class of 2019<\/a>. (January 2019)\r\n\r\nJessica Ables is named Laughlin Fellow, American College of Psychiatrists<\/a>. (January 2019)\r\n\r\nJessica Ables is named a Leon Levy Fellow in Neuroscience<\/a>. (April 2018)\r\n\r\nJessica Ables is named Psychiatry Chief Resident for Research. (2018)\r\n\r\nJessica Ables receives the NIMH Outstanding Resident Award<\/a>. (July 2017)\r\n\r\nJessica Ables is named as a Junior Mentor for the Icahn School of Medicine MSTP. (2017)\r\n\r\n[\/et_pb_text][\/et_pb_column][\/et_pb_row][\/et_pb_section][et_pb_section fb_built=\"1\" module_id=\"projects\" module_class=\"projects-section\" _builder_version=\"3.22\" background_color=\"#f7f7f7\" background_image=\"https:\/\/labs.icahn.mssm.edu\/ableslab\/wp-content\/uploads\/sites\/306\/2019\/07\/epyc-gfp-amigo1-mcherry-nos1-ipn-light.jpg\" parallax=\"on\"][et_pb_row _builder_version=\"3.25\"][et_pb_column type=\"4_4\" _builder_version=\"3.0.47\" custom_padding=\"|||\" custom_padding__hover=\"|||\"][et_pb_text admin_label=\"projects\" _builder_version=\"3.27.4\"]\r\n

Projects<\/h3>\r\n[\/et_pb_text][et_pb_accordion icon_color=\"#00aeef\" _builder_version=\"4.9.0\" vertical_offset_tablet=\"0\" horizontal_offset_tablet=\"0\" text_orientation=\"left\" z_index_tablet=\"0\" toggle_text_shadow_horizontal_length_tablet=\"0px\" toggle_text_shadow_vertical_length_tablet=\"0px\" toggle_text_shadow_blur_strength_tablet=\"1px\" closed_toggle_text_shadow_horizontal_length_tablet=\"0px\" closed_toggle_text_shadow_vertical_length_tablet=\"0px\" closed_toggle_text_shadow_blur_strength_tablet=\"1px\" body_text_shadow_horizontal_length_tablet=\"0px\" body_text_shadow_vertical_length_tablet=\"0px\" body_text_shadow_blur_strength_tablet=\"1px\" body_link_text_shadow_horizontal_length_tablet=\"0px\" body_link_text_shadow_vertical_length_tablet=\"0px\" body_link_text_shadow_blur_strength_tablet=\"1px\" body_ul_text_shadow_horizontal_length_tablet=\"0px\" body_ul_text_shadow_vertical_length_tablet=\"0px\" body_ul_text_shadow_blur_strength_tablet=\"1px\" body_ol_text_shadow_horizontal_length_tablet=\"0px\" body_ol_text_shadow_vertical_length_tablet=\"0px\" body_ol_text_shadow_blur_strength_tablet=\"1px\" body_quote_text_shadow_horizontal_length_tablet=\"0px\" body_quote_text_shadow_vertical_length_tablet=\"0px\" body_quote_text_shadow_blur_strength_tablet=\"1px\" border_radii=\"on|3px|3px|3px|3px\" border_width_all=\"0.5px\" border_color_all=\"#00aeef\" box_shadow_horizontal_tablet=\"0px\" box_shadow_vertical_tablet=\"0px\" box_shadow_blur_tablet=\"40px\" box_shadow_spread_tablet=\"0px\" text_shadow_horizontal_length_tablet=\"0px\" text_shadow_vertical_length_tablet=\"0px\" text_shadow_blur_strength_tablet=\"1px\"][et_pb_accordion_item title=\"1. Nitric oxide in development of tolerance\" open=\"on\" _builder_version=\"4.9.0\"]\r\n\r\n\"\"\r\n\r\nThe interpeduncular nucleus (IPN) is a GABAergic nucleus that is characterized by high expression of neuronal nitric oxide synthase (NOS1) as well as striking vascularity. We have found that NOS1 is increased in IPN after chronic exposure to nicotine, and more recently, to oxycodone. We hypothesize that this increase in NOS1 mediates the development of tolerance to both the aversive and positive effects of drugs. Our goal is to determine if this increase in NOS1 in the IPN generalizes to all other drugs of abuse and might represent a target for the general treatment of addiction. Future studies will focus on visualizing nitric oxide release and the effects of nitric oxide on the epigenome, transcriptome and function of neurons in the reward circuitry.\r\n\r\n[\/et_pb_accordion_item][et_pb_accordion_item title=\"2. Cholinergic vulnerability to hyperglycemia\" _builder_version=\"4.9.0\" open=\"off\"]\r\n\r\n\"\"Animal models of diabetes indicate that cholinergic neurons are particularly vulnerable to persistent hyperglycemia and resulting oxidative and nitrosative stress, and we hypothesize that this vulnerability may contribute to the neurocognitive and affective impairments observed in diabetic patients. The medial habenula (MHb) is a highly conserved cholinergic nucleus in the epithalamus that projects to the IPN to regulate levels of serotonin, dopamine and epinephrine and, as a result, mood. The MHb is susceptible to degeneration after repeated administration of drugs of abuse, however, to date no one has examined the effect of persistent hyperglycemia on the functional or structural plasticity of the MHb. Our goal is to understand the molecular, cellular and functional consequences of persistent hyperglycemia on cholinergic neurons in the reward circuitry using cell-type specific epigenomic and transcriptional profiling in combination with viral-mediated gene transfer.\r\n\r\n[\/et_pb_accordion_item][et_pb_accordion_item title=\"3. Axonal transcriptome\" title_tablet=\"3. Axonal transcriptome\" title_phone=\"3. Axonal transcriptome\" _builder_version=\"4.9.0\" vertical_offset_tablet=\"0\" vertical_offset_phone=\"0\" horizontal_offset_tablet=\"0\" horizontal_offset_phone=\"0\" background_color_gradient_direction_tablet=\"180deg\" background_color_gradient_direction_phone=\"180deg\" background_color_gradient_start_position_tablet=\"0%\" background_color_gradient_start_position_phone=\"0%\" background_color_gradient_end_position_tablet=\"100%\" background_color_gradient_end_position_phone=\"100%\" z_index_tablet=\"1\" z_index_phone=\"1\" hover_transition_duration_tablet=\"300ms\" hover_transition_duration_phone=\"300ms\" hover_transition_delay_tablet=\"0ms\" hover_transition_delay_phone=\"0ms\" body_text_shadow_horizontal_length_tablet=\"0px\" body_text_shadow_horizontal_length_phone=\"0px\" body_text_shadow_vertical_length_tablet=\"0px\" body_text_shadow_vertical_length_phone=\"0px\" body_text_shadow_blur_strength_tablet=\"1px\" body_text_shadow_blur_strength_phone=\"1px\" body_link_text_shadow_horizontal_length_tablet=\"0px\" body_link_text_shadow_horizontal_length_phone=\"0px\" body_link_text_shadow_vertical_length_tablet=\"0px\" body_link_text_shadow_vertical_length_phone=\"0px\" body_link_text_shadow_blur_strength_tablet=\"1px\" body_link_text_shadow_blur_strength_phone=\"1px\" body_ul_text_shadow_horizontal_length_tablet=\"0px\" body_ul_text_shadow_horizontal_length_phone=\"0px\" body_ul_text_shadow_vertical_length_tablet=\"0px\" body_ul_text_shadow_vertical_length_phone=\"0px\" body_ul_text_shadow_blur_strength_tablet=\"1px\" body_ul_text_shadow_blur_strength_phone=\"1px\" body_ol_text_shadow_horizontal_length_tablet=\"0px\" body_ol_text_shadow_horizontal_length_phone=\"0px\" body_ol_text_shadow_vertical_length_tablet=\"0px\" body_ol_text_shadow_vertical_length_phone=\"0px\" body_ol_text_shadow_blur_strength_tablet=\"1px\" body_ol_text_shadow_blur_strength_phone=\"1px\" body_quote_text_shadow_horizontal_length_tablet=\"0px\" body_quote_text_shadow_horizontal_length_phone=\"0px\" body_quote_text_shadow_vertical_length_tablet=\"0px\" body_quote_text_shadow_vertical_length_phone=\"0px\" body_quote_text_shadow_blur_strength_tablet=\"1px\" body_quote_text_shadow_blur_strength_phone=\"1px\" box_shadow_horizontal_tablet=\"0px\" box_shadow_horizontal_phone=\"0px\" box_shadow_vertical_tablet=\"0px\" box_shadow_vertical_phone=\"0px\" box_shadow_blur_tablet=\"40px\" box_shadow_blur_phone=\"40px\" box_shadow_spread_tablet=\"0px\" box_shadow_spread_phone=\"0px\" text_shadow_horizontal_length_tablet=\"0em\" text_shadow_horizontal_length_phone=\"0em\" text_shadow_vertical_length_tablet=\"0em\" text_shadow_vertical_length_phone=\"0em\" text_shadow_blur_strength_tablet=\"0em\" text_shadow_blur_strength_phone=\"0em\" toggle_text_shadow_horizontal_length_tablet=\"0px\" toggle_text_shadow_horizontal_length_phone=\"0px\" toggle_text_shadow_vertical_length_tablet=\"0px\" toggle_text_shadow_vertical_length_phone=\"0px\" toggle_text_shadow_blur_strength_tablet=\"1px\" toggle_text_shadow_blur_strength_phone=\"1px\" closed_toggle_text_shadow_horizontal_length_tablet=\"0px\" closed_toggle_text_shadow_horizontal_length_phone=\"0px\" closed_toggle_text_shadow_vertical_length_tablet=\"0px\" closed_toggle_text_shadow_vertical_length_phone=\"0px\" closed_toggle_text_shadow_blur_strength_tablet=\"1px\" closed_toggle_text_shadow_blur_strength_phone=\"1px\" open=\"off\"]\r\n\r\n\"\"Recent research has revealed that neuronal axons have specialized mechanisms to regulate delivery and utilization of mRNAs independently of the neuronal cell body, where the nucleus resides. This is not surprising given that in many cases (e.g. motor neurons in the limbs), the axons are far removed from the cell body and require the ability to respond to stimuli on timescales that would prohibit gene expression from the nucleus and subsequent delivery to the distal axon. Projection neurons in the brain provide a unique opportunity to profile the transcripts that are utilized in discrete compartments of the cell, as the axons are physically separate from the cell body. Our lab is currently profiling axonal transcriptomes in specific cell populations in the normal mouse brain during fear learning. Our goal is to determine how translation is locally regulated in response to various stimuli, including stress and metabolic derangements.\r\n\r\n[\/et_pb_accordion_item][\/et_pb_accordion][\/et_pb_column][\/et_pb_row][\/et_pb_section][et_pb_section fb_built=\"1\" module_id=\"team\" module_class=\"team-section\" _builder_version=\"3.22\" background_color=\"#ffffff\"][et_pb_row admin_label=\"team\" _builder_version=\"3.25\" custom_margin=\"||-50px|\"][et_pb_column type=\"4_4\" _builder_version=\"3.0.47\" custom_padding=\"|||\" custom_padding__hover=\"|||\"][et_pb_text admin_label=\"team\" _builder_version=\"4.9.0\" hover_enabled=\"0\" sticky_enabled=\"0\"]\r\n

Current Team<\/h3>\r\n[\/et_pb_text][\/et_pb_column][\/et_pb_row][et_pb_row column_structure=\"1_4,1_4,1_4,1_4\" _builder_version=\"4.9.0\"][et_pb_column type=\"1_4\" _builder_version=\"3.0.47\" custom_padding=\"|||\" custom_padding__hover=\"|||\"][et_pb_image src=\"https:\/\/labs.icahn.mssm.edu\/ableslab\/wp-content\/uploads\/sites\/306\/2019\/07\/Jess-headshot3.jpg\" align_tablet=\"center\" align_phone=\"\" align_last_edited=\"on|desktop\" _builder_version=\"3.23\" border_radii=\"on|4px|4px|4px|4px\"][\/et_pb_image][et_pb_text admin_label=\"Mount Sinai\" _builder_version=\"4.9.0\" hover_enabled=\"0\" sticky_enabled=\"0\"]\r\n\r\nJessica Ables, MD\/PhD<\/strong>\r\nAssistant Professor\r\njessica.ables@mssm.edu<\/a>\r\n\r\n[\/et_pb_text][et_pb_image src=\"https:\/\/labs.icahn.mssm.edu\/ableslab\/wp-content\/uploads\/sites\/306\/2021\/09\/Sam-Brown-scaled.jpg\" align_tablet=\"center\" align_phone=\"\" align_last_edited=\"on|desktop\" _builder_version=\"4.9.0\" vertical_offset_tablet=\"0\" horizontal_offset_tablet=\"0\" max_width=\"70%\" z_index_tablet=\"0\" border_color_all=\"#ffffff\" box_shadow_horizontal_tablet=\"0px\" box_shadow_vertical_tablet=\"0px\" box_shadow_blur_tablet=\"40px\" box_shadow_spread_tablet=\"0px\"][\/et_pb_image][et_pb_text admin_label=\"Mount Sinai\" _builder_version=\"4.9.0\" vertical_offset_tablet=\"0\" horizontal_offset_tablet=\"0\" z_index_tablet=\"0\" text_text_shadow_horizontal_length_tablet=\"0px\" text_text_shadow_vertical_length_tablet=\"0px\" text_text_shadow_blur_strength_tablet=\"1px\" link_text_shadow_horizontal_length_tablet=\"0px\" link_text_shadow_vertical_length_tablet=\"0px\" link_text_shadow_blur_strength_tablet=\"1px\" ul_text_shadow_horizontal_length_tablet=\"0px\" ul_text_shadow_vertical_length_tablet=\"0px\" ul_text_shadow_blur_strength_tablet=\"1px\" ol_text_shadow_horizontal_length_tablet=\"0px\" ol_text_shadow_vertical_length_tablet=\"0px\" ol_text_shadow_blur_strength_tablet=\"1px\" quote_text_shadow_horizontal_length_tablet=\"0px\" quote_text_shadow_vertical_length_tablet=\"0px\" quote_text_shadow_blur_strength_tablet=\"1px\" header_text_shadow_horizontal_length_tablet=\"0px\" header_text_shadow_vertical_length_tablet=\"0px\" header_text_shadow_blur_strength_tablet=\"1px\" header_2_text_shadow_horizontal_length_tablet=\"0px\" header_2_text_shadow_vertical_length_tablet=\"0px\" header_2_text_shadow_blur_strength_tablet=\"1px\" header_3_text_shadow_horizontal_length_tablet=\"0px\" header_3_text_shadow_vertical_length_tablet=\"0px\" header_3_text_shadow_blur_strength_tablet=\"1px\" header_4_text_shadow_horizontal_length_tablet=\"0px\" header_4_text_shadow_vertical_length_tablet=\"0px\" header_4_text_shadow_blur_strength_tablet=\"1px\" header_5_text_shadow_horizontal_length_tablet=\"0px\" header_5_text_shadow_vertical_length_tablet=\"0px\" header_5_text_shadow_blur_strength_tablet=\"1px\" header_6_text_shadow_horizontal_length_tablet=\"0px\" header_6_text_shadow_vertical_length_tablet=\"0px\" header_6_text_shadow_blur_strength_tablet=\"1px\" box_shadow_horizontal_tablet=\"0px\" box_shadow_vertical_tablet=\"0px\" box_shadow_blur_tablet=\"40px\" box_shadow_spread_tablet=\"0px\"]\r\n\r\nSamantha Brown<\/strong>\r\nMD\/PhD Student (2021-)\r\nsamantha.brown@icahn.mssm.edu<\/a>\r\n\r\n[\/et_pb_text][\/et_pb_column][et_pb_column type=\"1_4\" _builder_version=\"3.0.47\" custom_padding=\"|||\" hover_enabled=\"0\" custom_padding__hover=\"|||\" sticky_enabled=\"0\"][et_pb_image src=\"https:\/\/labs.icahn.mssm.edu\/ableslab\/wp-content\/uploads\/sites\/306\/2021\/09\/Mo-Jodieri.jpg\" align_tablet=\"center\" align_phone=\"\" align_last_edited=\"on|desktop\" _builder_version=\"4.9.0\" vertical_offset_tablet=\"0\" horizontal_offset_tablet=\"0\" max_width=\"70%\" z_index_tablet=\"0\" border_color_all=\"#ffffff\" box_shadow_horizontal_tablet=\"0px\" box_shadow_vertical_tablet=\"0px\" box_shadow_blur_tablet=\"40px\" box_shadow_spread_tablet=\"0px\"][\/et_pb_image][et_pb_text admin_label=\"Mount Sinai\" _builder_version=\"4.9.0\" vertical_offset_tablet=\"0\" horizontal_offset_tablet=\"0\" hover_enabled=\"0\" z_index_tablet=\"0\" text_text_shadow_horizontal_length_tablet=\"0px\" text_text_shadow_vertical_length_tablet=\"0px\" text_text_shadow_blur_strength_tablet=\"1px\" link_text_shadow_horizontal_length_tablet=\"0px\" link_text_shadow_vertical_length_tablet=\"0px\" link_text_shadow_blur_strength_tablet=\"1px\" ul_text_shadow_horizontal_length_tablet=\"0px\" ul_text_shadow_vertical_length_tablet=\"0px\" ul_text_shadow_blur_strength_tablet=\"1px\" ol_text_shadow_horizontal_length_tablet=\"0px\" ol_text_shadow_vertical_length_tablet=\"0px\" ol_text_shadow_blur_strength_tablet=\"1px\" quote_text_shadow_horizontal_length_tablet=\"0px\" quote_text_shadow_vertical_length_tablet=\"0px\" quote_text_shadow_blur_strength_tablet=\"1px\" header_text_shadow_horizontal_length_tablet=\"0px\" header_text_shadow_vertical_length_tablet=\"0px\" header_text_shadow_blur_strength_tablet=\"1px\" header_2_text_shadow_horizontal_length_tablet=\"0px\" header_2_text_shadow_vertical_length_tablet=\"0px\" header_2_text_shadow_blur_strength_tablet=\"1px\" header_3_text_shadow_horizontal_length_tablet=\"0px\" header_3_text_shadow_vertical_length_tablet=\"0px\" header_3_text_shadow_blur_strength_tablet=\"1px\" header_4_text_shadow_horizontal_length_tablet=\"0px\" header_4_text_shadow_vertical_length_tablet=\"0px\" header_4_text_shadow_blur_strength_tablet=\"1px\" header_5_text_shadow_horizontal_length_tablet=\"0px\" header_5_text_shadow_vertical_length_tablet=\"0px\" header_5_text_shadow_blur_strength_tablet=\"1px\" header_6_text_shadow_horizontal_length_tablet=\"0px\" header_6_text_shadow_vertical_length_tablet=\"0px\" header_6_text_shadow_blur_strength_tablet=\"1px\" box_shadow_horizontal_tablet=\"0px\" box_shadow_vertical_tablet=\"0px\" box_shadow_blur_tablet=\"40px\" box_shadow_spread_tablet=\"0px\" sticky_enabled=\"0\"]\r\n\r\nMohammad Jodeiri Farshbaf, PhD<\/strong>\r\nPostdoctoral Researcher (2021-)\r\nMohammad.JodeiriFarshbaf@mssm.edu<\/a>\r\n\r\n[\/et_pb_text][et_pb_image _builder_version=\"4.9.0\" _module_preset=\"default\" title_text=\"Sep 20 2021WTC2031\" src=\"https:\/\/labs.icahn.mssm.edu\/ableslab\/wp-content\/uploads\/sites\/306\/2022\/10\/Sep-20-2021WTC2031.jpg\" hover_enabled=\"0\" sticky_enabled=\"0\"][\/et_pb_image][et_pb_text admin_label=\"Mount Sinai\" _builder_version=\"4.9.0\" vertical_offset_tablet=\"0\" horizontal_offset_tablet=\"0\" hover_enabled=\"0\" z_index_tablet=\"0\" text_text_shadow_horizontal_length_tablet=\"0px\" text_text_shadow_vertical_length_tablet=\"0px\" text_text_shadow_blur_strength_tablet=\"1px\" link_text_shadow_horizontal_length_tablet=\"0px\" link_text_shadow_vertical_length_tablet=\"0px\" link_text_shadow_blur_strength_tablet=\"1px\" ul_text_shadow_horizontal_length_tablet=\"0px\" ul_text_shadow_vertical_length_tablet=\"0px\" ul_text_shadow_blur_strength_tablet=\"1px\" ol_text_shadow_horizontal_length_tablet=\"0px\" ol_text_shadow_vertical_length_tablet=\"0px\" ol_text_shadow_blur_strength_tablet=\"1px\" quote_text_shadow_horizontal_length_tablet=\"0px\" quote_text_shadow_vertical_length_tablet=\"0px\" quote_text_shadow_blur_strength_tablet=\"1px\" header_text_shadow_horizontal_length_tablet=\"0px\" header_text_shadow_vertical_length_tablet=\"0px\" header_text_shadow_blur_strength_tablet=\"1px\" header_2_text_shadow_horizontal_length_tablet=\"0px\" header_2_text_shadow_vertical_length_tablet=\"0px\" header_2_text_shadow_blur_strength_tablet=\"1px\" header_3_text_shadow_horizontal_length_tablet=\"0px\" header_3_text_shadow_vertical_length_tablet=\"0px\" header_3_text_shadow_blur_strength_tablet=\"1px\" header_4_text_shadow_horizontal_length_tablet=\"0px\" header_4_text_shadow_vertical_length_tablet=\"0px\" header_4_text_shadow_blur_strength_tablet=\"1px\" header_5_text_shadow_horizontal_length_tablet=\"0px\" header_5_text_shadow_vertical_length_tablet=\"0px\" header_5_text_shadow_blur_strength_tablet=\"1px\" header_6_text_shadow_horizontal_length_tablet=\"0px\" header_6_text_shadow_vertical_length_tablet=\"0px\" header_6_text_shadow_blur_strength_tablet=\"1px\" box_shadow_horizontal_tablet=\"0px\" box_shadow_vertical_tablet=\"0px\" box_shadow_blur_tablet=\"40px\" box_shadow_spread_tablet=\"0px\" sticky_enabled=\"0\"]\r\n\r\nAdriana Mendez\r\n<\/strong>Neuroscience PhD Student (2022-)\r\nadriana.mendez@icahn.mssm.edu<\/a>\r\n\r\n[\/et_pb_text][\/et_pb_column][et_pb_column type=\"1_4\" _builder_version=\"3.0.47\" custom_padding=\"|||\" custom_padding__hover=\"|||\"][et_pb_image src=\"https:\/\/labs.icahn.mssm.edu\/ableslab\/wp-content\/uploads\/sites\/306\/2020\/11\/headshotfinalKN.jpg\" align_tablet=\"center\" align_phone=\"\" align_last_edited=\"on|desktop\" _builder_version=\"3.23\" max_width=\"70%\" border_color_all=\"#ffffff\"][\/et_pb_image][et_pb_text admin_label=\"Mount Sinai\" _builder_version=\"3.27.4\"]\r\n\r\n\u00a0\r\n\r\n[\/et_pb_text][\/et_pb_column][et_pb_column type=\"1_4\" _builder_version=\"3.0.47\" custom_padding=\"|||\" custom_padding__hover=\"|||\"][\/et_pb_column][\/et_pb_row][et_pb_row admin_label=\"team\" _builder_version=\"3.25\" custom_margin=\"||-50px|\"][et_pb_column type=\"4_4\" _builder_version=\"3.0.47\" custom_padding=\"|||\" custom_padding__hover=\"|||\"][et_pb_text admin_label=\"team\" _builder_version=\"4.9.0\" hover_enabled=\"0\" sticky_enabled=\"0\"]\r\n\r\nTaelor Matos<\/strong>\r\nPREP Student (2023-)\r\ntaelor.matos@icahn.mssm.edu\r\n\r\nNatasha Rice<\/strong>\r\nMaster's Student (2023-)\r\n

Current Volunteers<\/h3>\r\nJake Tetenman - Washington University at St. Louis\r\n\r\nZim Khan - McNair Scholar, Hunter College, CUNY\r\n\r\nHridika Tasnim - McNair Scholar, Hunter College, CUNY\r\n\r\n[\/et_pb_text][\/et_pb_column][et_pb_column type=\"1_4\" _builder_version=\"3.0.47\" custom_padding=\"|||\" custom_padding__hover=\"|||\"][\/et_pb_column][\/et_pb_row][et_pb_row admin_label=\"team\" _builder_version=\"3.25\" custom_margin=\"||-50px|\"][et_pb_column type=\"4_4\" _builder_version=\"3.0.47\" custom_padding=\"|||\" custom_padding__hover=\"|||\"][et_pb_text admin_label=\"team\" _builder_version=\"4.9.0\" hover_enabled=\"0\" sticky_enabled=\"0\"]\r\n

Former Members<\/h3>\r\n[\/et_pb_text][\/et_pb_column][\/et_pb_row][et_pb_row column_structure=\"1_4,1_4,1_4,1_4\" _builder_version=\"4.9.0\" hover_enabled=\"0\" sticky_enabled=\"0\" collapsed=\"off\"][et_pb_column type=\"1_4\" _builder_version=\"3.0.47\" custom_padding=\"|||\" hover_enabled=\"0\" custom_padding__hover=\"|||\" sticky_enabled=\"0\"][et_pb_image src=\"https:\/\/labs.icahn.mssm.edu\/ableslab\/wp-content\/uploads\/sites\/306\/2019\/07\/Zainab-NSM_0009-2.jpg\" align_tablet=\"center\" align_phone=\"\" align_last_edited=\"on|desktop\" _builder_version=\"3.23\" border_radii=\"on|4px|4px|4px|4px\"][\/et_pb_image][et_pb_text admin_label=\"Mount Sinai\" _builder_version=\"4.9.0\" hover_enabled=\"0\" sticky_enabled=\"0\"]\r\n\r\nZainab Oketokoun<\/strong>\r\nAssociate Researcher (2018-2022)\r\n\r\n[\/et_pb_text][\/et_pb_column][et_pb_column type=\"1_4\" _builder_version=\"3.0.47\" custom_padding=\"|||\" hover_enabled=\"0\" custom_padding__hover=\"|||\" sticky_enabled=\"0\"][et_pb_image _builder_version=\"4.9.0\" _module_preset=\"default\" title_text=\"Chino1\" src=\"https:\/\/labs.icahn.mssm.edu\/ableslab\/wp-content\/uploads\/sites\/306\/2022\/10\/Chino1.jpg\" hover_enabled=\"0\" sticky_enabled=\"0\"][\/et_pb_image][et_pb_text admin_label=\"Mount Sinai\" _builder_version=\"4.9.0\" hover_enabled=\"0\" sticky_enabled=\"0\"]\r\n\r\nChino Nwakama<\/strong>\r\nUniversity of Minnesota - SURP4US<\/a> Student (2022) - Now an MSTP student at Icahn School of Medicine at Mount Sinai\r\n\r\n[\/et_pb_text][\/et_pb_column][et_pb_column type=\"1_4\" _builder_version=\"3.0.47\" custom_padding=\"|||\" custom_padding__hover=\"|||\"][et_pb_image _builder_version=\"4.9.0\" _module_preset=\"default\" title_text=\"2023_haller\" src=\"https:\/\/labs.icahn.mssm.edu\/ableslab\/wp-content\/uploads\/sites\/306\/2022\/10\/2023_haller.jpg\" hover_enabled=\"0\" sticky_enabled=\"0\"][\/et_pb_image][et_pb_text admin_label=\"Mount Sinai\" _builder_version=\"4.9.0\" hover_enabled=\"0\" sticky_enabled=\"0\"]\r\n\r\nJillian Haller<\/strong>\r\nScranton University - Undergraduate Volunteer (2022)\r\n\r\nKrist Niblo<\/strong>\r\nMaster's Student - (2020-2023)\r\n\r\n[\/et_pb_text][\/et_pb_column][et_pb_column type=\"1_4\" _builder_version=\"3.0.47\" custom_padding=\"|||\" custom_padding__hover=\"|||\"][\/et_pb_column][\/et_pb_row][et_pb_row admin_label=\"team\" _builder_version=\"3.25\" custom_margin=\"||-50px|\"][et_pb_column type=\"4_4\" _builder_version=\"3.0.47\" custom_padding=\"|||\" custom_padding__hover=\"|||\"][et_pb_text admin_label=\"team\" _builder_version=\"4.9.0\" hover_enabled=\"0\" sticky_enabled=\"0\"]\r\n

Former Volunteers<\/h3>\r\nGabby Chavez (2018-2023) - Pelham Memorial High School & Fordham University\r\n\r\nMartha Solomon (2019) - SUNY Downstate Medical Student\r\n\r\nNazeen Shah (2021-2022) -Spackenkill High School\r\n\r\nAlmer Yu (2022) - Hunter College High School\r\n\r\nYacoub Alokam - St. Francis College Undergraduate\r\n\r\nSophia Leng - Hunter College High School\r\n\r\nAlp Vargelci - Stuyvesant High School\r\n\r\nNatalia Zheng - Stuyvesant High School\r\n\r\nNamrata Marjit, MS - Icahn School of Medicine\r\n\r\nStella Lodewick - Clemson University\r\n\r\n[\/et_pb_text][\/et_pb_column][et_pb_column type=\"1_4\" _builder_version=\"3.0.47\" custom_padding=\"|||\" custom_padding__hover=\"|||\"][\/et_pb_column][\/et_pb_row][et_pb_row admin_label=\"team\" _builder_version=\"3.25\" custom_margin=\"||-50px|\"][et_pb_column type=\"4_4\" _builder_version=\"3.0.47\" custom_padding=\"|||\" custom_padding__hover=\"|||\"][et_pb_text admin_label=\"team\" _builder_version=\"4.9.0\" hover_enabled=\"0\" sticky_enabled=\"0\"]\r\n\r\n[\/et_pb_text][\/et_pb_column][et_pb_column type=\"1_4\" _builder_version=\"3.0.47\" custom_padding=\"|||\" custom_padding__hover=\"|||\"][\/et_pb_column][\/et_pb_row][\/et_pb_section][et_pb_section fb_built=\"1\" module_id=\"positions\" module_class=\"positions-section\" _builder_version=\"3.22\" custom_margin=\"||5em|\"][et_pb_row admin_label=\"team\" _builder_version=\"3.25\" custom_margin=\"||-50px|\"][et_pb_column type=\"4_4\" _builder_version=\"3.0.47\" custom_padding=\"|||\" custom_padding__hover=\"|||\"][et_pb_divider divider_style=\"dotted\" divider_position=\"center\" divider_weight=\"0.5\" _builder_version=\"3.19.10\" height=\"25px\" custom_margin=\"-5em||2em|\"][\/et_pb_divider][et_pb_text admin_label=\"Postitions\" _builder_version=\"3.27.4\" hover_enabled=\"0\" sticky_enabled=\"0\"]\r\n

Potential Lab Members<\/h3>\r\nIcahn School of Medicine at Mount Sinai is seeking enthusiastic, detail-oriented applicants. The School is one of the nation\u2019s leading medical schools, ranked in the top 20 schools for NIH funding. Both the Psychiatry and Neuroscience Departments offer an outstanding intellectual and multidisciplinary research environment with a commitment to translational research. Note that we do not offer observerships for foreign medical graduates.<\/strong>\r\n\r\nVolunteers:\u00a0<\/strong>\r\nWe typically accept 1-2 high school and 1-2 undergraduate volunteers each year, with the majority of the time in the lab spent during the summer. Volunteers are expected to work independently with supervision after training. Interested candidates should send their resume\/CV in January<\/strong> for a summer position.\r\n\r\nGraduate Students:<\/strong>\r\nAll graduate students interested in our lab must first apply and be accepted into a program at Mount Sinai.<\/a>\r\n\r\nPostdoctoral Fellows:<\/strong>\r\nPostdoctoral candidates should have a Ph.D. and\/or M.D. and a strong basic science<\/strong> background in molecular\/cellular neuroscience.\u00a0Those with experience in the following fields are particularly encouraged to apply: computational approaches for analysis of sequencing datasets, machine learning approaches for animal behavior, electrophysiology, fiber photometry or in vivo imaging.\r\n\r\nInterested candidates should submit their Curriculum Vitae and contact information for at least three professional references to Jessica.ables@mssm.edu.\r\n\r\n[\/et_pb_text][\/et_pb_column][\/et_pb_row][\/et_pb_section][et_pb_section fb_built=\"1\" _builder_version=\"3.22\" background_color=\"#000000\" border_width_all=\"0.5px\" border_color_bottom=\"#00aeef\"][et_pb_row column_structure=\"1_4,1_4,1_4,1_4\" _builder_version=\"3.25\" background_size=\"initial\" background_position=\"top_left\" background_repeat=\"repeat\"][et_pb_column type=\"1_4\" _builder_version=\"3.0.47\" custom_padding=\"|||\" custom_padding__hover=\"|||\"][et_pb_text _builder_version=\"3.27.4\" text_text_color=\"#ffffff\"]\r\n\r\nLocation<\/strong>\r\nANNENBERG BUILDING 19-38\r\nIcahn School of Medicine at Mount Sinai\r\n1 Gustave L. Levy Pl, New York, NY 10029\r\n\r\n[\/et_pb_text][\/et_pb_column][et_pb_column type=\"1_4\" _builder_version=\"3.0.47\" custom_padding=\"|||\" custom_padding__hover=\"|||\"][\/et_pb_column][et_pb_column type=\"1_4\" _builder_version=\"3.0.47\" custom_padding=\"|||\" custom_padding__hover=\"|||\"][\/et_pb_column][et_pb_column type=\"1_4\" _builder_version=\"3.0.47\" custom_padding=\"|||\" custom_padding__hover=\"|||\"][\/et_pb_column][\/et_pb_row][\/et_pb_section]","_et_gb_content_width":"","footnotes":""},"class_list":["post-8","page","type-page","status-publish","hentry"],"aioseo_notices":[],"_links":{"self":[{"href":"https:\/\/labs.icahn.mssm.edu\/ableslab\/wp-json\/wp\/v2\/pages\/8","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/labs.icahn.mssm.edu\/ableslab\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/labs.icahn.mssm.edu\/ableslab\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/labs.icahn.mssm.edu\/ableslab\/wp-json\/wp\/v2\/users\/337"}],"replies":[{"embeddable":true,"href":"https:\/\/labs.icahn.mssm.edu\/ableslab\/wp-json\/wp\/v2\/comments?post=8"}],"version-history":[{"count":77,"href":"https:\/\/labs.icahn.mssm.edu\/ableslab\/wp-json\/wp\/v2\/pages\/8\/revisions"}],"predecessor-version":[{"id":434,"href":"https:\/\/labs.icahn.mssm.edu\/ableslab\/wp-json\/wp\/v2\/pages\/8\/revisions\/434"}],"wp:attachment":[{"href":"https:\/\/labs.icahn.mssm.edu\/ableslab\/wp-json\/wp\/v2\/media?parent=8"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}