The academic affiliation between the Icahn School of Medicine at Mount Sinai (ISMMS) and Rensselaer Polytechnic Institute (RPI) fosters educational and research collaborations and stimulates the development of new technologies to radically improve the diagnosis and treatment of human disease.
The ISMMS-RPI Steering Committee has issued a request for proposals for collaborative projects in the area of oncology. This RFP builds on themes (listed below) developed during the recent symposium “New Connections in Cancer Research: Bridging Basic Science, Clinical Science, Engineering and New Technologies.” Other topics related to cancer may also be proposed.
Imaging, mechanical and biophysical approaches
- Effects of mechanical and physical forces on tumor growth and metastasis
- Biochemical and biophysical makeup of the tumor microenvironment: implications for cancer progression and therapy
- Development of analytic tools to monitor cell populations and individual cells in vitro and in vivo
- Development or refinement of advanced imaging methods for cancer detection and monitoring
Systematic identification of personalized cancer therapies
- Cost-effective target/drug discovery platforms
- Development/implementation of personalized immunotherapeutic approaches
- Optimization of individualized chemotherapy regimen (combination, order, dose, schedule,…)
- Strategies/tools for clinical testing of experimental personalized therapies
- Strategies for managing and reducing treatment side effects
Systematic identification of cancer biomarkers
- Prediction of tumor progression (e.g., survival rather than objective response)
- Improved prediction of immunotherapy/drug response
Proposals should be submitted with the expectation that data generated will lead to submission(s) for extramural funding from the NIH and/or other external funding sources. If possible, the intended extramural grant program should be specified.
Applications should include at least one investigator each from ISMMS and RPI. All investigators with full-time academic appointments within the Mount Sinai Health System and at Rensselaer are invited to apply. Applications from participants of the recent Cancer symposium at Mount Sinai are particularly encouraged to form teams that can respond to this RFP.
The ISMMS-RPI Steering Committee will review the seed grant proposals and funding will commence in January 2017.
For further details, interested researchers can click here for the Request for Proposals.
Deadline Rhyme Just for You Before Holiday Time:
To Faculty and Staff,
From the GCO you hear sometimes once a week.
“GCO/NIH Updates” we hope is your Friday treat.
“GCO Helpful Hints” we release as need be.
Here’s one on deadlines to put under your Christmas tree
Or by a Chanukah menorah
Or a Kwanzaa candelabra
Or however you may celebrate the holiday bonanza.
Better yet, place in a high profile spot
Like a bulletin board or a trash receptacle not.
Remember these dates and submissions will go smoother
Better than plucking a four leaf cloover.
“Clover,” you say? I say, “You are right.
Now let’s get on with the rhyme, if I may be so forthright.”
ISMMS Funded Projects – One Business Day
Now that’s a call for a “Hip, Hip Hurray!”
Federal Non-Competitive Applications
Means NIH and other federal yearly continuations.
GCO policy is a two business day turnaround.
Nice to see a smile rather than a frown.
Federal Competitive Grant and Contract Applications
Those are the new /resubmission /comp. renewal submissions.
Five business days by 11 am the GCO does require.
It can save you for sure from a potential quagmire.
All other funded projects* – just one business day.
Another call for a “Hip, hip hurray!”
You made the GCO deadline. Way to go! You’re not done yet.
Wait for the GCO receipt before acknowledging faith in kismet.
InfoEd submissions do arrive like well packaged presents.
But upon review, they are missing a few segments.
Remember the GCO policy of “COMPLETE and FINAL”
Including signed Sinai Central forms and all else for no GCO denial.
Be blessed with good tidings from the GCO
For another successful year, Ho, Ho Ho.
— Allison Gottlieb, Director, Sponsored Programs Education, (and Poet Laureate) Grants and Contracts Office
For complete deadline information, click here (last page).
* Please contact your assigned Grants Specialist in advance regarding any additional time the GCO may need in the review and approval process if you are applying for a sponsored project with complex budgetary and/or administrative requirements (e.g., non- federal application with many subawards, international extramural funding agency application with nonstandard budget forms).
ConduITS, the Institutes for Translational Sciences is delighted to announce the start of a new National Center for Advancing Translational Sciences (NCATS) funded program called the STTEP-UP Initiative in Science and Medicine.
This program is designed to enable highly motivated under-represented minority (URM) trainees in residency, subspecialty fellowship training, or postdoctoral laboratory positions within our healthcare system to become innovative leaders and entrepreneurs in clinical and translational research. It is designed to provide candidates with the critical thinking skills to evaluate the validity and implications of the published literature and plethora of available information through digital and internet resources; formulate testable hypotheses; design informative, effective and efficient studies; analyze data correctly; and interpret quantitative and qualitative findings and their potential impact on the health of individuals across the life cycle.
The components of the program include:
- Academic Skills:
- Time management & work/life balance
- Communication Styles
- Team Science
- Practical Tips for Negotiating your Career
- Must Know Financial Concepts
- INCHOIR Learning Lab, which will entail participation in hands-on training in clinical and translational science, utilizing an established data repository for secondary data analysis, and monthly didactics on fundamentals in interventional studies culminating in a two day virtual clinical trial development workshop.
- Opportunities for Multidisciplinary Teamwork with other trainees throughout the education process.
- Individual Career Development with Primary Mentor & Interdisciplinary Mentor Team
- Career Development Seminars in the following topics:
- Loan Repayment Program
- Diversity Supplements
- Mentored Awards Roadmap
- T32 Networking Seminar Series
- “Meet the Expert” Mentored Investigator “K Club Series”
- Annual Next Steps Symposium, which will highlight nationally-renowned URM Clinical and Translational Investigators
The Clinical Research Education Program currently seeks nominations for the academic year starting July 1, 2017 – June 30, 2018. This competitive program utilizes an NCATS funded NRSA TL1 mechanism and provides salary support and tuition dollars for four postdoctoral trainees per year. Applicants will be asked to provide a brief overview (not less than one paragraph and not more than one page) concerning their prior, current and/or upcoming involvement in a research project as well as their motivation for embracing a career in clinical translational research,* and a current curriculum vitae including bibliography. Applicants must also submit a letter of recommendation from their Training Program Director and Division Chief or Department/Institute/Center Chairperson. These respective letters should indicate that the training program director, division chief or department/institute/center chairperson is committed to make time available for the trainee to participate in the required academic programs. Please send required documents and information by March 13, 2017 to the attention of Christine Acevedo (Christine.Acevedo@mssm.edu), administrative assistant for the Clinical Research Education Program. If you have any specific questions, please feel free to email or contact the Clinical Research Education Program office at 212-824-7014.
*If an applicant has recently developed or submitted a research proposal or protocol, the specific aim page or synopsis respectively can be used instead.
Stony Brook Medicine and Icahn School of Medicine at Mount Sinai have announced a Seed Grant program designed to support highly meritorious and innovative research focusing on biomedical discovery, health, and the community. Several $20,000-100,000 awards will be funded over one or two years. Awardees will utilize these funds to support interdisciplinary, basic and applied research, and/or community-based research with the potential to advance health, add value to clinically-relevant diagnostic and therapeutic technologies, or to facilitate development of commercially-promising biomedical intellectual property. Requests to support joint faculty meetings and small group retreats will also be considered.
Application deadline for the first cycle is by the close of the business day on Friday December 9, 2016 with funding to commence in February 2017.
There will be a second cycle within 6 months or 1 year as the program team gauges demand.
The Department of Corporate and Foundation Relations of the Mount Sinai Development Office provides this curated list of funding opportunities to find faculty who may be interested and to offer assistance with the application process. Please see below for some of their upcoming deadlines, and contact them at CorpFoundHelp@mountsinai.org, if you would like to find out more.
American Society of Nephrology Funding for New Investigators: https://www.asn-online.org/grants/career/
The ASN Foundation for Kidney Research awards these grants to advance the independent careers of young investigators in biomedical research.
- Career Development Grants for New Investigators
- Next deadline cycle will open on October 19 and close on December 14, 2016 at 2 PM
- Please see website for additional funding opportunities and schedules
American Federation for Aging Research 2017 Grants: http://www.afar.org/research/funding/
Since 1981, AFAR has provided over $160 million to nearly 3,200 talented investigators and students. AFAR offers grants at all different levels of investigation, from student to senior investigator.
- Deadlines and amounts are varied, please see website for details regarding specific grants
Pancreatic Action Network 2017 Research Funding Opportunities: https://www.pancan.org/research/grants-program/
Five funding mechanisms are now accepting applications from postdoctoral fellows, junior independent researchers and senior investigators. We are also announcing our two new targeted grants (in early detection and precision medicine) that will open in December.
- Projects are normally funded for a period of four years, in the range of $750,000 over the term of the project.
- Deadlines: Various, please see website
The KL2 mentored career development program, a part of Mount Sinai’s ConduITS, Institutes for Clinical and Translational Sciences, has announced the solicitation of applications from junior faculty and post-doctoral fellows for the KL2 Scholars awards for 2017. The award’s application process is described in detail in the 2017 KL2 Faculty Scholars Award RFA. Interested faculty and fellows can also refer to the 2017 KL2 Awards FAQ, CV Format MSSM, Detailed Budget template, and Letter of Intent documents for additional information. Applicants should be committed to careers in clinical translational research and must be nominated by their Department chairs or Institute directors. Departments, Divisions, and Institutes are encouraged to collaborate in ways that jointly sponsor award recipients. Two to three 2-year NIH funded awards are being offered for 2017 and the application timeline is as follows:
- December 5th, 2016 – Structured letter of intent (LOI) must be emailed to KL2email@example.com by 4 PM
- February 3rd 2017 – Full Applications must be submitted by 4PM. Electronic (email) submission is required (KL2firstname.lastname@example.org ). Please see the RFA for details regarding the complete application.
- September 2017 – award notifications
- November 1st, 2017 – Start of funding
For questions and application advice: Please contact Fatima Nabizada-Pace at (212) 824-7264 or Christine Acevedo (212-824-7014) or KL2email@example.com
Have you ever thought about quitting your day job for something more exciting and meaningful like the life of a super hero where you can take down evil villains while traveling the world at supersonic speed through fire, flood, earthquake, and wind storm?
Yes, that thought has crossed my mind once or twice but I always got cold feet at the prospect of getting bogged down by a technical snafu, like the door in the telephone booth jamming as Superman completed his costume change or Spider-Man’s under the wrist web gizmo malfunctioning. It’s always those technicalities that can bring down an operation. Lucky for us at Mount Sinai, our PIs don’t need to quit their day job but can remain super heroes on their own turf while avoiding those seemingly petty but potentially fatal foibles.
Here is a list of GCO’s top technical and administrative errors that will stop your NIH competitive application dead in its tracks like the Bat Mobile running out of gas or stalled on the road.
By the way, that is a photo of my son ready to battle the bad guys or perhaps NIH cyber application moles? (For those into important details, you might notice the remnants of the energy boosting power snack, chocolate, on the super hero’s face.)
#1 Driving without GPS or a Road Map? Use GCO’s Application Submission Checklist and Instructions
Use GCO’s Application Submission Checklist and Instructions each and every time you submit to the GCO (i.e., think words of encouragement and not a requirement). There are 20 steps listed that may be applicable to your application. Miss a step like forgetting your InfoEd eForm or all the subaward documentation or your co-investigator has an expired FCOIR education certification? Your Bat Mobile has stalled on the road and is sinking in quicksand fast.
#2 Selecting Your Destination? Remember to Use the NIH Assignment Request Form and NOT a Cover Letter
For those super hero vehicles that must be parked in the garage of a specific study section, remember to use the new NIH Assignment Request Form and not a cover letter. You would select this optional form in the InfoEd SetUp questions. Please see complete Instructions for the Assignment Request Form on the NIH site.
#3 Attention PIs and Mentors – Forgot your ID? It’s called “Sponsor Credentials”
PIs and mentors must enter their eRA Commons ID into InfoEd. You would enter the information in “My Profile” in “Sponsor Credentials” section. Another option is for staff working on the application to add it in “Sponsor Credentials” box right in the Personnel tab for the investigator. Without it, it’s like being pulled over on the side of the road for driving without your ID. In this case, you can’t even return home. You’re just stuck out there on the open road in the hot blazing sun. Need an eRA Commons ID? E-mail firstname.lastname@example.org, indicate your role on the project and the GCO will assign one to you.
#4 On the Wrong Road from the Get Go? Check to Make Sure the NIH Institute / Center Will Accept your R03 or R21 Application or other non-R01 parent application
Did you know that not all NIH Institutes and Centers (IC) accept the R03 and R21 and other non-R01 applications in response to a Parent Announcement? When reading the Parent Announcement, you’ll see right at the top the “Components of Participating Organizations” section, which means the institutes/centers that will accept the application. ICs that do not participate in the announcement will not consider applications for funding.
#5 Are these Human Subjects in My Super Hero Vehicle? What are Specimens?
Are human samples expedited, exempt, or not human subjects research? The confusion is especially prevalent around coded or deidentified specimens. Please follow the first FAQ to help make the determination: https://humansubjects.nih.gov/human-specimens-cell-lines-data.
#6 Toll Bridge Ahead – New Enrollment Tables and Differences in Planned vs. Cumulative Enrollment
Planned means prospective enrollment; cumulative means you are using previously collected samples/specimens/data (for example, if using a biorepository). There are different instructions for completing the tables, depending on which type of enrollment is selected. For example, if you select “Planned”, but input numbers into the “Unknown” category, it generates an error, as this column is only for cumulative enrollment. (GCO has a fill list of table validations available upon request.) Can one select both “Planned” and “Cumulative” on the same table? No, this is not possible. It has to be either or; if using both, then two tables, one for each type of enrollment, is required.
#7 Want to Race Through the NIH Cyber Highway at Warp Speed During Rush Hour? Even Super Heroes Must Follow Traffic Rules
The warp speed button on everyone’s super hero vehicle has been disabled by Management. It is purely ornamental and doesn’t work. The GCO must be in receipt of the COMPLETE AND FINAL proposal, including completed and signed Conflict of Interest and Suspension and Debarment forms 5 business days prior to the NIH deadline by 11 am to guarantee an on-time delivery to NIH. In addition, please see NIH Competitive Application Due Date Information. There always seem to be unforeseen circumstances so do plan ahead and submit on time.
#8 Change the Radio Dial on Your Bat Mobile from the Biosketch Blues to Something More Upbeat?
GCO reminds PIs and staff in the review process that many items must be removed from the Biosketch page like pending awards, or grants completed more than 3 years ago, or completed projects that are listed as still active. You might want to get a jump start on the process by reviewing the Biosketches prior to submission to the GCO. Please see the NIH Biosketch Instructions and Sample pages.
#9 File Attachments: Beware of the “&” and Really Looooooooooooooooooong Attachment Titles
Your InfoEd file PDF file attachments that get exported into the NIH forms are like little passengers in your Bat Mobile. They need to be loaded in just right. Please follow these Dos and Don’ts adapted from:
- Save all document attachments with descriptive filenames of 50 characters or less (including spaces).
- Use unique filenames for all attachments in an application (or within a component of a multi-project application).
- Use any of the following characters: A-Z, a-z, 0-9, underscore, hyphen, space, period, parenthesis, curly braces, square brackets, tilde, exclamation point, comma, semi colon, apostrophe, at sign, number sign, dollar sign, percent sign, plus sign, and equal sign.
- Use one space (not two or more) between words or characters and do not begin the filename with a space or include a space immediately before the .pdf extension
- Use the ampersand (“&”) since it requires special formatting.
Questions about Sponsored Projects? Please click here for a listing of Departmental Grants Specialists at the GCO who can assist you.
Because Your History is Our Future™
Incorporate BioMe™ Biobank into your research project, today, by sending your inquiries through the BioMe™ Biobank Program’s access portal here: https://ipm.mssm.edu/biobank/service/.
Since September 2007, 35,000 Mount Sinai Medical Center patients have available samples in the Electronic Medical Record-linked BioMe™ Biobank developed at the Institute for Personalized Medicine (IPM). BioMe™ is designed to generate a large collection of DNA and plasma samples, as well as genomic data and phenotype/family history/lifestyle data that are stored in a way that protects patients’ privacy while enabling IRB-approved research to be performed on such specimens linked to de-identified comprehensive electronic clinical information extracted from the Mount Sinai Data Warehouse. To discover better treatments, researchers are seeking to unravel the complexity of disease at the most basic level through “molecular” studies. The donation of samples from many thousands of individuals is essential to such studies. BioMe™ is dedicated to advancing the application of human blood-derived biospecimen and clinical data to life science research to accelerate the development of personalized healthcare and medical solutions.
For more information or if you have any questions, please contact BioMeBiobank@mssm.edu.