Yiannis Ioannou PhD Honored as the 2017 Mount Sinai Inventor of the Year

The 2017 Mount Sinai Inventor of the Year Award was presented to Yiannis Ioannou, PhD  at the SinaInnovations Awards Ceremony on October 16 for his groundbreaking research and entrepreneurial spirit in bringing his research “from bench to bedside.”

Dr. Ioannou’s work in lysosomal storage diseases led to the first ever treatment for Fabry disease, in collaboration with Robert Desnick, MD, PhD, and the discovery of small-molecules that may serve as the basis for novel therapies for the treatment of numerous lysosomal storage diseases, including those with severe neurodegenerative effects. Yiannis’ commitment to seeing these discoveries translated into products that benefit patients and his tireless effort as an inventor-collaborator with Mount Sinai Innovation Partners culminated in the launch of a new company in partnership with institutional investors in early 2017.

The Mount Sinai Inventor of the Year Award was created to recognize individual or collaborative investigators in the Mount Sinai Health System. The award offers $10,000 to the recipient whose research is making, or has the potential to make, significant positive and product-driven impacts on health. The 2016 recipient was Dennis Charney, MD, Anne and Joel Ehrenkranz Dean of the Icahn School of Medicine at Mount Sinai and President for Academic Affairs for the Mount Sinai Health System.

Watch the video highlighting Dr. Ioannou’s research endeavors and his inspiration for commercializing his technology with MSIP.


Act on your Innovative Impulses NOW – Fall Innovation Events at Mount Sinai

If you are an innovator and/or entrepreneur at heart, please make sure you join Mount Sinai Innovation Partners (MSIP) for one of their many fall innovation events – spanning the Mount Sinai Innovators Group (MSIG) that meets monthly, visiting companies like Johnson & Johnson JLABS and “smithwise” who will share best practices on how medical devices are developed and brought to market, as well as a seminar on the Ins and Outs of SBIR/STTR funding – and many more. MSIP is looking forward to hearing about your Eureka moments, and collaborating with you to get your bright idea into products and services that benefit patients and society. Share your commercially-relevant translational discoveries and inventions with MSIP!

In the next few weeks, MSIP has the following exciting events. For other fall events and programming, please see their events calendar here. Should you have any questions about MSIP, MSIG and other future innovation events you would like to see, please contact Cynthia Cleto.

Mount Sinai Innovation Group (MSIG) Launch Meeting @ Annenberg 16-02
September 14 @ 4:00 pm – 6:00 pm

Do you have an idea for a healthcare innovation that could possibly benefit patients in the long run? If so, the Mount Sinai Innovation Group (MSIG) is the place for you. MSIG brings together students, faculty, and staff currently working on entrepreneurial and innovative projects to share experiences, learn approaches to technology commercialization, and develop new technologies. MSIG’s first meeting will be held on Thursday, September 14 where we will cover the essentials of Intellectual Property and Commercialization – a must if you are looking towards a technology that may be developed into a product or service for the healthcare marketplace. Both our speakers have experience in the startup community, and we will be peppering them with questions about this process as well. This will be followed by a networking reception, where you can meet fellow innovators and entrepreneurs within the community. Future meetings will feature experts in medical devices, the startup space and more!

Presentation and discussion: 4 – 5pm
Networking reception: 5 – 6pm
Topic: Essentials for Entrepreneurs: Intellectual Property and Commercialization
Guest Speakers: Justin Ring (Contracts & Licensing Associate) and Simon Gruber (Business Development Analyst) from Mount Sinai Innovation Partners


ELABNYC 2018 Information Session @ Annenberg 16-02
Sep 19 @ 12:00 pm – 1:30 pm
Date: Tuesday, September 19
Time: 12 – 1:30 pm
Location: Annenberg 16-02
Lunch will be served.

If you are an entrepreneur by heart, please join MSIP at an information session to learn first-hand about the ELabNYC 2018 program.

  • Ask your questions face to face.
  • Hear about the new program plans for 2018.
  • Learn what you need to do to submit a strong application.
  • Meet alums from Mount Sinai.
  • Talk to ELabNYC program team.

Register here.

Application Deadline: October 23, 2017 at  5:00 PM. For more information, visit: www.ELabNYC.com.

Reference Management Classes Offered by Levy Library

Reference management tools allow researchers to collect, organize, and store bibliographic information about source material such as journal articles, books, reports, and multimedia. A reference management tool also makes creating and formatting bibliographies and in-text citations easy. Levy Library offers a series of Reference Management classes throughout September. These tools are invaluable to researchers at all levels conducting of facilitating the literature search process.

Introduction to EndNote
Discover what millions of researchers, scholarly writers, students and librarians already know about the power of EndNote to search online databases, organize references, images and PDFs. In this class, you will practice using EndNote X8 to collect, organize and maintain a ‘library’ of references, find and save full-text journal articles, and insert and format references in a MS Word document. The class will also cover searching and exporting citations from PubMed and Web of Science and syncing your desktop library with EndNote Online.

Date: Tuesday, September 12, 2017
Time: 3:00pm – 4:00pm
Location: Levy Library Small Classroom (ANBG11-40)

Introduction to Zotero
Join us for Introduction to Zotero, a powerful, easy-to-use research tool that helps you gather, organize, and analyze sources and then automatically generate in-text citations and bibliographies. Please being your laptop to this class in order to take advantage of the workshop-style of the session.

Date: Tuesday, September 19, 2017
Time: 3:00pm – 4:00pm
Location: Annenberg 10-72

Make the Most of Mendeley
Join us for Make the Most of Mendeley. Mendeley is a powerful, easy-to-use research tool that helps you gather, organize, and share sources and then automatically generate in-text citations and bibliographies. This session will introduce new users to the tool as well as ensure that existing users are aware of all of Mendeley’s exciting functionalities. Please being your laptop to this class in order to take advantage of the workshop-style of the session.

Date: Tuesday, September 26, 2017
Time: 3:00pm – 4:00pm
Location: Annenberg 10-72

Follow the Levy Library on Twitter @Levy_Library to learn about their events and initiatives.

Leadership in Emerging Academic Departments (LEAD Program) Academy Seeks Applications

LEAD LogoApplications are sought (deadline October 31, 2017) for the annual Leadership Emerging in Academic Departments (LEAD) Academy, sponsored by Conduits, the Institute for Translational Sciences and the Office of Academic Development and Enrichment in collaboration with UT Southwestern Medical Center.

Leadership is about influence and the ability to make things happen, not just “being in charge.” Leadership skills are critical for the success of faculty at all stages of development and are of particular importance in the emerging landscape of Team Science. The curriculum includes modules in self-discovery, communication, influence, negotiation, difficult conversations, inspiring trust and embracing diversity. The format includes:  didactic lectures, case studies and experiential activities. Participants will work with an executive coach and anchor the LEAD learning objectives with an Individual Capstone Leadership Project.  Kick off session will be on February 2nd, 2018 and subsequent classes will occur on the 1st Friday of the month (in most instances) these are the dates as follows: (1st Friday of the month): March 2nd, April 6th, May 4th, June 1st, July 12th and 13th (2nd Thursday and Friday 9am-4pm),  August 3rd, September 7th, October 5th, November 2nd, December 7th, 2018, January 4th, 2019 and January 18th, 2019 from 11am-3pm. All classes are mandatory; nominations should come with assurance that Director, Chair and/or Division Chief will provide protected time for participation.


  • To develop and/or refine leadership skills for faculty success during any stage of the academic career.


  • Applicants must meet the following qualifications:

All Assistant Professors (MDs, PhDs, MD/PhDs) and Associate Professors are eligible. Women faculty and underrepresented minority faculty are particularly encouraged to apply.
Applicants: The following materials must be submitted electronically through RedCap (see link below)
Deadline: October 31st, 2017

  1. A completed online application found at https://www.inchoir.org/redcap/redcap/surveys/?s=48FCX4MNN8
  2. Letter of Nomination from Department Chair, Center/Institute Director or Division Chief
  3. Curriculum Vitae.

Applicants will be considered by an Executive Committee. Notification of selection for this program will be provided by the LEAD Program Director and Co-Directors. If you have any questions, please contact us: Janice Gabrilove, MD (janice.gabrilove@mssm.edu) or Crispin Goytia (crispin.goytia@mountsinai.org)

Supported by National Institute for Advancing Translational Sciences (NCATS) & the Office of Academic Development and Enrichment, Icahn School of Medicine at Mount Sinai in collaboration with UT Southwestern

The LEAD Program at ISMMS is modeled after the successful LEAD Program established at UTSW as collaboration between the Office of Faculty Diversity & Development, Office of Women’s Careers, Organizational Development & Training, Human Resources, Faculty Leaders at UTSW and Center for Translational Medicine

Check Out On Line Partnership to Accelerate Research (OnPAR)

Globally approximately 85% of the research applications submitted to government funding agencies go unfunded. This leaves an innovation gap that may stifle research discovery and delay discoveries that could advance potential treatments and cures for many diseases.

OnPAR seeks to provide a funding alternative to the research community’s restraints imposed by limitations in government funding. OnPAR members include private foundations, pharmaceuticals and other private funders that will review research ideas submitted for consideration. The more research ideas OnPAR gets, the more funders will join to potentially partner and fund research projects, and the closer we will be to treatments and the potential cures for our communities.

The goal of OnPAR is to fund highly scored unfunded applications from NIH, NSF, FDA, CDC, DOE, NASA and other funding agencies –national and international.  Internationally, the EU Commission, E-rare (conglomerate of 26 EU government funding agencies), UK MRC and Innovate UK, Canada CIHR, Aus NHMRC, Japan AMED, NASA, the Department of Energy will start joining in the Fall.  Some have already confirmed. For a one page summary on OnPAR, click here.

Resources for Drug Discovery from the Screening Lab

The Assay Development and Screening Core for Drug Discovery has announced that their resource is running on its full capacity and invited researchers to utilize it. In addition, they seek screening collaboration with their Principal Investigators. The mission of this Core is to accelerate and enhance drug discovery research through close collaboration with investigators to identify valuable targets, establish reliable assays, and perform medium to high throughput screenings of small molecule and antibody libraries. For more information, contact Jianxi Liu, Ph.D., Senior Scientist with the Drug Discovery Institute.


Pepper Center Requests for Proposals to Support Innovative Pilot Projects and Junior Investigators

Mount Sinai’s Claude D. Pepper Older American’s Independence Center (“Pepper Center”) innovative mission is to stimulate, develop, and fund research to improve quality of life and independence of older adults with serious illness and their caregivers. This multiyear program project grant from the National Institute of Aging has helped to create a foundation of pioneering research in aging and palliative care at Mount Sinai, and has helped to improve care for our nation’s sickest patients.

The goals of Mount Sinai’s Pepper Center are to identify, recruit and train leaders in aging and palliative care research as well as provide funds to support pilot and exploratory projects related to aging and palliative care.  TWO REQUESTS FOR PROPOSALS TO DIRECTLY SUPPORT PILOT AND EXPLORATORY PROJECTS AS WELL AS SUPPORT ACADEMIC DEVELOPMENT FOR JUNIOR CLINICIANS:

  • The Pilot and Exploratory Core provides support for investigators at all levels to propose innovative projects aimed at improving the care of older adults with serious illness.
  • The Research and Education Component provides support for salary and coursework for talented junior investigators interested in pursuing a career in research (basic, translation, and health services) related to the care of older adults with serious illness.

For additional information, please review the requests for proposals (linked above), which include information about funding opportunities as well as timelines. Please contact Ashleigh Manning (Ashleigh.Manning@mssm.edu) for additional information.

The Mount Sinai OAIC (Older American’s Independence Center) is supported by a grant from the National Institute of Aging (2P30AG028741; Albert Siu, PI).


Mount Sinai’s Brain Fair Inspiring the Next Generation of Researchers

Each year Mount Sinai’s Brain Fair is bigger and better and reaches more people than the year before. This year was no exception, hosting over 400 school children from neighborhood public schools and other members of our local community.

This year’s Brain Fair, ultimately held on Friday May 5, had to overcome a major complication: the original date was cancelled due to New York’s snowstorm in March. Despite this obstacle, the Brain Fair was a huge success. Check out this video https://youtu.be/hX_V_MtAmag.

A tremendous thank you goes to Neuroscience Graduate Students Ana Badimon, Carla Golden, Casey Lardner, and Zefa Sullivan, co-directors of MINDS (Mentoring in Neuroscience Discovery at Sinai). Special thanks also go to Alyson Davis of CEYE (Director, Center for Excellence in Youth Education) as well as Marilyn Balamaci, Elizabeth Dowling, Rose Ferrer, Alison Malouk, Chloe Politis, Jaime Rodriguez, and Veronica Szarejko. Their dedication, commitment, and passion, and recognition of the importance of sharing excitement about the brain with our community neighbors, is inspiring.

Join us next year for this great event.


Joint ISMMS-RPI Oncology Projects Request for Proposals Released – Deadline 12/15/16

The academic affiliation between the Icahn School of Medicine at Mount Sinai (ISMMS) and Rensselaer Polytechnic Institute (RPI) fosters educational and research collaborations and stimulates the development of new technologies to radically improve the diagnosis and treatment of human disease.

The ISMMS-RPI Steering Committee has issued a request for proposals for collaborative projects in the area of oncology. This RFP builds on themes (listed below) developed during the recent symposium “New Connections in Cancer Research: Bridging Basic Science, Clinical Science, Engineering and New Technologies.” Other topics related to cancer may also be proposed.

Imaging, mechanical and biophysical approaches

  • Effects of mechanical and physical forces on tumor growth and metastasis
  • Biochemical and biophysical makeup of the tumor microenvironment: implications for cancer progression and therapy
  • Development of analytic tools to monitor cell populations and individual cells in vitro and in vivo
  • Development or refinement of advanced imaging methods for cancer detection and monitoring

Systematic identification of personalized cancer therapies

  • Cost-effective target/drug discovery platforms
  • Development/implementation of personalized immunotherapeutic approaches
  • Optimization of individualized chemotherapy regimen (combination, order, dose, schedule,…)
  • Strategies/tools for clinical testing of experimental personalized therapies
  • Strategies for managing and reducing treatment side effects

Systematic identification of cancer biomarkers

  • Prediction of tumor progression (e.g., survival rather than objective response)
  • Improved prediction of immunotherapy/drug response

Proposals should be submitted with the expectation that data generated will lead to submission(s) for extramural funding from the NIH and/or other external funding sources. If possible, the intended extramural grant program should be specified.

Applications should include at least one investigator each from ISMMS and RPI. All investigators with full-time academic appointments within the Mount Sinai Health System and at Rensselaer are invited to apply. Applications from participants of the recent Cancer symposium at Mount Sinai are particularly encouraged to form teams that can respond to this RFP.

The ISMMS-RPI Steering Committee will review the seed grant proposals and funding will commence in January 2017.

For further details, interested researchers can click here for the Request for Proposals.

Please contact Louise Lammers or Jack Huang with any questions.

STTEP-UP for Research – Sinai Team-based Translational Education Program URM Propeller Launched

ConduITS, the Institutes for Translational Sciences is delighted to announce the start of a new National Center for Advancing Translational Sciences (NCATS) funded program called the STTEP-UP Initiative in Science and Medicine.

This program is designed to enable highly motivated under-represented minority (URM) trainees in residency, subspecialty fellowship training, or postdoctoral laboratory positions within our healthcare system to become innovative leaders and entrepreneurs in clinical and translational research. It is designed to provide candidates with the critical thinking skills to evaluate the validity and implications of the published literature and plethora of available information through digital and internet resources; formulate testable hypotheses; design informative, effective and efficient studies; analyze data correctly; and interpret quantitative and qualitative findings and their potential impact on the health of individuals across the life cycle.

The components of the program include:

  • Academic Skills:
    • Time management & work/life balance
    • Mentorship
    • Communication Styles
    • Leadership
    • Team Science
    • Practical Tips for Negotiating your Career
    • Must Know Financial Concepts
  • INCHOIR Learning Lab, which will entail participation in hands-on training in clinical and translational science, utilizing an established data repository for secondary data analysis, and monthly didactics on fundamentals in interventional studies culminating in a two day virtual clinical trial development workshop.
  • Opportunities for Multidisciplinary Teamwork with other trainees throughout the education process.
  • Individual Career Development with Primary Mentor & Interdisciplinary Mentor Team
  • Career Development Seminars in the following topics:
    • Loan Repayment Program
    • Diversity Supplements
    • Mentored Awards Roadmap
  • T32 Networking Seminar Series
  • “Meet the Expert” Mentored Investigator “K Club Series”
  • Annual Next Steps Symposium, which will highlight nationally-renowned URM Clinical and Translational Investigators

The Clinical Research Education Program currently seeks nominations for the academic year starting July 1, 2017 – June 30, 2018. This competitive program utilizes an NCATS funded NRSA TL1 mechanism and provides salary support and tuition dollars for four postdoctoral trainees per year. Applicants will be asked to provide a brief overview (not less than one paragraph and not more than one page) concerning their prior, current and/or upcoming involvement in a research project as well as their motivation for embracing a career in clinical translational research,* and a current curriculum vitae including bibliography. Applicants must also submit a letter of recommendation from their Training Program Director and Division Chief or Department/Institute/Center Chairperson. These respective letters should indicate that the training program director, division chief or department/institute/center chairperson is committed to make time available for the trainee to participate in the required academic programs. Please send required documents and information by March 13, 2017 to the attention of Christine Acevedo (Christine.Acevedo@mssm.edu), administrative assistant for the Clinical Research Education Program. If you have any specific questions, please feel free to email or contact the Clinical Research Education Program office at 212-824-7014.

*If an applicant has recently developed or submitted a research proposal or protocol, the specific aim page or synopsis respectively can be used instead.