ResearchMatch.org Launches Spanish Website

ResearchMatch (RM) is the national online recruitment tool that matches people interested in research with investigators throughout the United States. ResearchMatch has just launched a Spanish version of the website inviting Spanish speakers to sign-up in Spanish, enabling researchers from the Mount Sinai Health System to use ResearchMatch to connect with and recruit Spanish-speaking volunteers for their studies.

RM is a not-for-profit activity and is funded through the NIH’s CTSA program. With more than 131,000 registered volunteers and over 6,100 investigators at 154 participating institutions, ResearchMatch hopes to increase the pool of Spanish-speaking volunteers and to increase the recruitment of underrepresented groups in research.

Are you a Mount Sinai Health System Researcher interested in learning more about ResearchMatch? Register now or attend an online training!

Every initial submission to the IRB should include for approval:

  1. The use of ResearchMatch as a recruitment strategy*
  2. Your ResearchMatch contact message**
  3. Your REDCap prescreening (eligibility) survey – if desired.

* If not included on an initial submission, ResearchMatch should be added as a recruitment strategy in an amendment submission.

**Your RM contact message cannot contain study team contact information or survey links and must be less than 2,000 characters.

Already registered with ResearchMatch and wanting to recruit Spanish-speaking volunteers? Submit any Spanish contact messages to your IRB for approval (including any other participant-facing materials, such as consent forms) and ensure you are prepared for inquiries from Spanish-speaking volunteers.

Share ResearchMatch with people you know that are interested in finding out about research studies, and help us grow the number of volunteers in the New York metropolitan area!

Contact the Office of Research Services via its Research 411 Portal’s Research Subject Recruitment form by selecting ResearchMatch.org Assistance, if you have any questions or need help with the process at Mount Sinai Health System.

 

Office of Research Services Launches the Research 411 Portal

Do you need help navigating research systems at ISMMS?

The Research 411 Portal is the place to get answers to your questions about how to navigate the conduct of research throughout the MSHS. It is a help desk ticketing system where you can ask general questions through Research 411 or get help with the services that the Office of Research Services (ORS) offers. See the below menu of services offered. The ORS team is dedicated to helping researchers navigate the expanding research enterprise of the MSHS.

How to use the Research 411 Portal:

Go to the Office of Research Services (ORS) website and click on ORS Research 411 Portal. You will see the below menu of current Research 411 Portal tickets, click on a ticket, complete the form and hit send!

TIP: If you’re not sure which ticket to use, or if there isn’t a ticket for your specific questions, use the general Research 411 form at the top of the list of choices.

New services are continually added as the research enterprise continues to evolve. Announcements about new services will be made via the ISMMS Research Listserv. Please make sure that you are subscribed by entering your email address under “Research Listserv” on the  Research Web Portal’s Getting Started page (within the MSHS firewall) to ensure you stay informed.

 

Call for Applications: STTEP-UP Initiative in Science and Medicine

ConduITS, the Institutes for Translational Sciences is once again seeking applications for the 2018-2019 NCATS funded training program entitled the STTEP-UP Initiative in Science and Medicine.

This program is designed to enable highly motivated underrepresented minority (URM) trainees in residency, subspecialty fellowship training or postdoctoral laboratory positions within our health care system, to become innovative leaders and entrepreneurs in clinical and translational research. The program is designed to provide candidates with the critical thinking skills to evaluate the validity and implications of the published literature and plethora of available information through digital and internet resources; formulate testable hypotheses, design informative, effective and efficient studies, analyze data correctly and interpret quantitative and qualitative findings and their potential impact on the health of individuals across the life cycle.

The components of the program include:

  • Academic Skills:
    • Time management & work/life balance
    • Mentorship
    • Communication Styles
    • Leadership
    • Team Science
    • Practical Tips for Negotiating your Career
    • Must Know Financial Concepts
  • INCHOIR Learning Lab, which will entail participation in hands-on training in clinical and translational science, utilizing an established data repository for secondary data analysis, and monthly didactics on fundamentals in interventional studies culminating in a two day virtual clinical trial development workshop.
  • Opportunities for Multidisciplinary Teamwork with other trainees throughout the education process.
  • Individual Career Development with Primary Mentor & Interdisciplinary Mentor Team
  • Career Development Seminars in the following topics:
    • Loan Repayment Program
    • Diversity Supplements
    • Mentored Awards Roadmap
  • T32 Networking Seminar Series
  • “Meet the Expert” Mentored Investigator “K Club Series”
  • Annual Next Steps Symposium, which will highlight nationally-renowned URM Clinical and Translational Investigators

We are currently seeking nominations for the academic year starting July 1, 2018 – June 30, 2019. This competitive program utilizes an NCATS funded NRSA TL1 mechanism and provides salary support and tuition dollars for four postdoctoral trainees per year. Applicants will be asked to complete a full application and submit to Christine Acevedo (christine.acevedo@mssm.edu) by April 15, 2018. Full application includes:

  • Completed application form (NRSA TL1 Application Form 2018) which should include a brief overview concerning prior, current and/or upcoming involvement in a research project as well as the motivation for embracing a career in clinical translational research.*
  • Current curriculum vitae including bibliography.
  • 1 letter of recommendation from your Training Program Director; 1 letter of recommendation from your Division Chief or Department/Institute/Center Chairperson. These respective letters should indicate that the training program director, division chief or department/institute/center chairperson is committed to make time available for the trainee to participate in the required academic programs.

If you have any specific questions, please feel free to email or contact the office at 212-824-7014. We look forward to receiving your application.

* If an applicant has recently developed or submitted a research proposal or protocol, the specific aim page or synopsis respectively can be used instead.

 

Centralized FedEx Service Established

The Office of Research Services is pleased to announce that its piloted process for shipping biological substances for clinical trials via FedEx at Icahn School of Medicine at Mount Sinai has facilitated nearly 2000 shipments since its pilot in April 2016. Mailroom Assistant Manager Sybil Allen reports, “the program has been a great success, and I work very closely with the Manager at FedEx, who makes sure that the packages are picked up on time.” Due to consistently positive feedback and increasing traffic, growing to an average of 40 packages per week in recent weeks, this service is now available on an ongoing basis.

Clinical trial shipments with a FedEx pre-paid label can be dropped off at the mailroom by 4:00pm for same-day shipping. Any FedEx shipments after 4:00pm will continue to be the responsibility of the research team. The mailroom is located on the SB Level of 5 East 98th Street, and Assistant Manager Sybil Allen can be reached at (212) 241-6161 (x46161).

For all shipments, the study team must ensure the shipper is IATA Certified and that the label and packaging are in compliance with current regulations for shipping biological substances (http://www.un3373.com/info/regulations/). If you have any questions about shipping biological substances, please email Mark Matthews, Director of Environmental Health and Safety, at mark.matthews@mssm.edu.

If you have any questions regarding this process, please open a ticket with your question to the Office of Research Services via Research 411.

 

Annual Dean’s Healthcare System Team Science Award Nominations Sought by July 30th

Nominations are sought for the Annual Dean’s Healthcare System Award, sponsored by Conduits, the Institute for Translational Science. This award has been established to acknowledge and underscore the emerging importance of interdisciplinary teams to the translation of research discoveries into clinical applications.

This award is meant to recognize an outstanding interdisciplinary or transdisciplinary research team for its innovative and impactful science that has advanced or likely will advance the detection, diagnosis, prevention or treatment of disease. This research effort should ideally reflect a partnership between basic and clinical science and reflect a novel undertaking that would not have been accomplished by any single member of the team working in isolation.

For 2017, this award will focus on Team Science in Cancer Research, which often requires participation of investigations from a broad array of disciplines including biomedical science, genomics, Immunology, pharmacology & nanotechnology, systems biology, biomedical engineering, bioinformatics, clinical informatics, computational biology, experimental pathology, imaging, in vivo models, mHealth, Big Data analytics, biostatistics, population science clinical investigation and community engagement. A one thousand dollar prize will be given to the recipients of this Team Science Award.

Goals:

  • To showcase outstanding role models of collaborative, interdisciplinary and transdisciplinary research
  • To provide a venue to acknowledge the importance of Team Science in solving complex and meaningful problems, significantly impacting human health and advancing novel solutions in the field of cancer.

Eligibility:

  • Applicants must meet the following qualifications:

Team science collaboration: as evidenced by 3 or more members of a Team that reflect participation of both basic and clinical disciplines who have worked to address a major problems concerning the pathogenesis, diagnosis, monitoring, treatment, and/or prevention of cancer

Applicants: All Team Leaders must be employed by the Mount Sinai Health System (MSHS) or be on the faculty at Rensselaer Polytechnic Institute (RPI) or State University of New York (SUNY) at Stony Brook. Collaborators from industry, who are members of a given MSHS &/, RPI or Stony Brook investigative team, may be included.

Limit: MSHS, RPI and SUNY Stony Brook faculty and healthcare professionals may only participate in one Team Science Award application.

Program Guidelines:

Please submit the following materials as a single pdf by email to (Crispin.Goytia@mountsinai.org) on or before July 30th.

  • A 1-2 page summary, delineating the Team’s contribution to the field of cancer research, (including citation of published work), the gap in knowledge addressed and the impact of the research on human health.
  • Current standard CV and bibliography

Nominations will be considered by an Executive Committee and the recipients announced in August. Questions? Please contact Janice Gabrilove, MD (Janice.Gabrilove@mssm.edu) or Crispin Goytia (Crispin.Goytia@mssm.edu).

 

4D CTSA Technology Development Awards Announced

With support from ConduITS, the Institutes for Translational Sciences, the 4D (Discover, Design, Develop, Deliver) Technology Development Projects promote technology-based solutions for unmet needs across the healthcare system in therapeutics, diagnostics, devices, and digital health. This program takes a mentored approach to facilitate the teams executing their plans.

Please join us in congratulating the following team leaders awarded for this cycle (Fall 2016-March 2017):

  • Jamilia Sly, PhD Instructor, Department. of Oncological Sciences

Internet-Based Patient Activation Intervention to Improve Referrals for Cancer Screening (PAIRS)

  • Ya-El Mandel-Portnoy, 5th year PhD Candidate, Emergency Medicine K12 Scholar

Developing cutting-edge technology to improve the treatment and quality of life of Atrial Fibrillation patient

  • Sander Houten, PhD, Associate Professor Genetics and Genomic Sciences

Novel Treatments for Glutaric Aciduria

  • Ilse Daehn, PhD, Assistant Professor, Department of Medicine, Division of Nephrology

Predictive Biomarkers for Diabetic Nephropathy (DN)

  • Evren Azeloglu, PhD, Assistant Professor, Department of Pharmacological Sciences

Next Generation Bandages for Improved Wound Healing

If you would like more information about this program, please contact the Louise Lammers at louise.lammers@mssm.edu.

 

Rosalind Wright Assumes Leadership Roles in Translational Research

Effective November 1, Rosalind Wright, MD, MPH assumed the dual leadership roles of Dean of Translational Biomedical Research and Director of the Clinical and Translational Science Award (CTSA) at the Icahn School of Medicine at Mount Sinai.

As Dean for Translational Biomedical Research, Dr. Wright provides leadership for clinical and population-based research across the Mount Sinai Health System, applying her expertise and vast experience to supporting and growing our research endeavors. This role dovetails with her directorship of the CTSA, recently re-funded by the NIH to foster high-quality translational research, research education, and the development of innovative resources. Through Mount Sinai’s Conduits program, the CTSA spurs collaborations among clinicians, patients, and scientists, and builds partnerships across a national network of CTSA programs.

“As technological advances and evolving insights into disease causation and individual variation increase the complexity of research and its translation into clinical practice, we are challenged with moving forward integrated team science that informs what genes, environment and life stage mean to defining normal variations and altered health trajectories throughout the life course and across generations,” said Dr. Wright of her new roles. “This is an exciting time for science and medicine with Mount Sinai continuing to lead the way.”

Dr. Wright is a Professor in the Departments of Pediatrics and Preventive Medicine. As a pulmonologist and life course epidemiologist, she has special expertise in prenatal and early childhood factors contributing to the programming of chronic diseases. She has built a large National Institutes of Health (NIH)-funded research program focused on understanding the role of both chemical and non-chemical social stressors in perinatal programming of conditions such as asthma, obesity, cardiometabolic disorders, and neurodevelopment, particularly as they relate to health disparities in socioeconomically challenged urban populations. Dr. Wright’s pioneering research on the role of social factors and toxic stress on disease programming starting in pregnancy was recently recognized through her election as a fellow to the National Academy of Behavioral Medicine Research.

As we welcome Dr. Wright, we want to thank Hugh Sampson, MD, who is scaling back his administrative positions at Mount Sinai to assume a role as Chief Scientific Officer for DVB Technologies, a company that is developing treatments for pediatric food allergies. We wish him well in his new external position and, at the same time, are pleased that he will continue to be a visible, vibrant presence in the Icahn School of Medicine research community.

 

New Pre-screening Feature in ResearchMatch

ResearchMatch.org, the free, disease neutral, and secure registry of research study volunteers that is available to the Mount Sinai research community, has announced the launch of a new pre-screening feature for new and existing studies!

  • Now in addition to contacting volunteers with their IRB approved ResearchMatch ad, researchers will have the option of including a link to a REDCap pre-screening survey.
  • This allows them to pre-screen potential volunteers from the list of people that they contact.
  • Prescreening surveys must be created in REDCap and must be IRB approved.
  • The URL for the survey is simply uploaded into ResearchMatch when they upload their IRB ResearchMatch ad.

What will the potential volunteer see?

  • When the volunteer clicks “yes” on the confirmation page, they will then be redirected to the REDCap survey in question.
  • Their submitted survey goes directly to the researcher.
  • ResearchMatch will add that volunteer to the list on the Researchers Enrollment Continuum and mark them as ‘contact in process’.

What do the researchers need to do next?

  • Create a concise REDCap prescreening survey that will allow them to filter potential volunteers.
  • Ask for IRB approval. The questions must relate to the IRB approved study and should ask volunteers to provide their name and email in the survey for tracking.
  • Next time you use ResearchMatch for recruiting, add your new URL!

For questions, contact the Vanderbilt ResearchMatch Liaisons at info@researchmatch.org or Madrid Poultney, the Mount Sinai Institutional Liaison, at madrid.poultney@mssm.edu. For assistance with REDCap, contact Evie Andreopoulos at evie.andreopoulos@mountsinai.org.

Sign up for ResearchMatch training at https://www.researchmatch.org/researcher-training.

 

The Clinical Research Unit: Your Resource for Clinical-Translational Studies

For over 50 years the Clinical Research Unit (CRU) had been supported by NIH funding. Established in 1963 as a General Clinical Research Center, the current CRU was partially funded by a Clinical and Translational Science Award (CTSA). However, changes in the funding strategies of the National Center for Advancing Translational Sciences, which funds the CTSA, resulted in withdrawal of support for CRUs nationwide. With support from the Office of the Dean, as of April 2015, the Mount Sinai CRU continues to provide space and personnel to assist ongoing and new studies, but with elimination of CRU-hosted pilot study funding and reductions of ancillary services compared to those offered in past years.

Beginning April 1st, a new fee schedule has been implemented. For non-industry studies, including NIH, MSSM and foundation-sponsored studies as well Investigator Initiated pharma supported projects, the fee is $65 per hour. Industry initiated studies have a fee of $110 per hour.

The center is located on the 2nd floor of 1184 5th Avenue and provides space and personnel to facilitate clinical research studies. The clinical staff includes nurse practitioners, medical assistants, and a dietitian. The CRU offers resources to conduct physical examinations, phlebotomy, drug infusion, ECG, participant monitoring, specimen processing, and other services. There is space for study staff to work while tending to research participants. The unit is in operation 8:00am to 5:30pm, Monday through Friday.

The CRU would like to thank the research community for their patience during the recent transition and looks forward to continuing to provide high quality services to facilitate Mount Sinai clinical research. For applications and for any questions, please contact Christine Hannigan, Clinical Research Manager, 212-241-6045, christine.hannigan@mssm.edu.

REDCap – Capturing Data for Mount Sinai Researchers

Research Electronic Data Capture (REDCap) is web-based software for designing and conducting clinical trials, online surveys, and translational research. It was developed (2004) and is being maintained by the informatics core of the Vanderbilt University with the ongoing support of NCRR and NIH grants. Currently REDCap is used by 1,340 institutions in 88 countries.

REDCap is no-fee software for the institutional partners, and Icahn School of Medicine at Mount Sinai (ISMMS) has been a part of the REDCap consortium since 2011. It has rapidly become a preferred tool of data collection for researchers. Currently ISMMS REDCap has over 700 users, 200 projects, and 65,000 collected records. REDCap has many appealing features: easy to use (no programming skills are required), user friendly and secure web interface, easy to copy, share, and collaborate on projects, daily data backups, HIPAA compliant, and free for the researchers. It also has API capabilities and provides users with codes to seamlessly import their data to a variety of statistical software packages, such as R, SAS, or SPSS.

Two popular modules in REDCap are surveys and longitudinal data collections. REDCap surveys can be accessed through public survey link or personalized survey invitations sent via email. Invitations can be sent automatically. It possible to conduct anonymous pre and post surveys with all the responses still being linked.

The REDCap longitudinal module is extremely useful for data collection that is repeated over time. An investigator just creates one form and specifies when it has to be repeated. The scheduling module will help create follow up times that are auto-generated from the defined follow up events. The scheduling tool will automatically pre-populate the study’s project calendar.

Some additional REDCap capabilities:

  • randomization for multiple arm prospective trials
  • file repository
  • detailed log of everything that was done in a project
  • simple reports and queries
  • import of bulks of data
  • record locking
  • double data entry
  • user specific access rights
  • compatibility with most internet browsers
  • mobile and tablet friendly
  • training videos describing most of the REDCap tools
  • Vanderbilt’s Coursera course on data management using REDCap: www.coursera.org/course/datamanagement

New users can learn more about REDCap by attending quarterly Information Sessions held by the Center for Biostatistics at ISMMS. For now sessions are offered quarterly. Time and location of the sessions is announced in weekly Broadcast email. RSVP is required. Upcoming session is scheduled for March 13, 2015.

You can visit the ISMMS REDCap access page at https://www.inchoir.org/redcap. You will be asked for a username and password that can be assigned to you by the REDCap team.

If you would like to set up a REDCap account or have any questions, you can contact

Maria Suprun maria.suprun@mssm.edu
Vincent Dobrev vincent.dobrev@mountsinai.org