The National Center for Advancing Translational Sciences (NCATS) launched the SMART IRB to provide standard operating procedures to facilitate a single IRB model for multi-site studies. All 64 CTSA hubs across the country have signed on to SMART IRB including ConduITS, Icahn School of Medicine’s Institutes of Translational Sciences, as well as a number of academic sites that are not in the CTSA network (~180 to date).
Freely available for institutions and investigators, SMART IRB is an integrated, comprehensive platform that allows flexibility in the size and scope of collaboration to enable IRB reliance for multi-site studies across the nation, regardless of funding status. Interested MSHS researchers must contact the Program for the Protection of Human Subjects (PPHS), which supports ISMMS’s participation in the SMART IRB initiative and has procedures to work with the SMART IRB as a Relying institution. In order to initiate SMART IRB review, researchers must go through the ISMMS PPHS Ideate electronic submission system.
The SMART IRB Online Reliance System is a unique tool that helps institutions establish and document single IRB review arrangements. By using this system:
- Investigators can create and submit requests to use a single IRB for their studies.
- Collaborating institutions can work together to identify a Reviewing IRB and track and document reliance arrangements on a study-by-study basis.
- Users have a clear understanding of next steps and are notified when action is required.
The SMART IRB Online Reliance System became available in beta on May 4, 2017. For more information about using the SMART IRB system at MSHS, email email@example.com.