Projects and Grants

1R01-HL116329-04                         (Migliaccio PI)                   09/26/2012 – 06/30/2017
NIH/DHHS/NHLBI
The human glucocorticoid receptor and normal and pathological terminal erythroid differentiation.
The scope of this project is to investigate the role exerted by signaling from the glucocorticoid receptor in the regulation of terminal erythroid differentiation under normal conditions and in erythropoietin-resistant anemias.

5PO1-CA108671-09                        (Hoffman PI)                        07/1/2004 – 06/30/2016
Mouse Models of Myelofibrosis  Project 4, (Migliaccio PI)
The scope of this project is to exploit the Gata1low model to detail the pathobiological pathway leading to development of stem/progenitor cell trafficking and extramedullary hematopoiesis in primary myelofibrosis.

Completed Support 

PO1-CA108671                  (Hoffman PI)                                        07/01/2006 – 06/30/2011
Mouse Models of Myelofibrosis Project 4, (Migliaccio PI)
The scope of this project is to exploit the Gata1low model to detail the pathobiological pathway leading to development of stem/progenitor cell trafficking and extramedullary hematopoiesis in primary myelofibrosis.

New York State Foundation for Science      (Migliaccio PI)           2007 –    2011
Personalized therapies for Sickle Cell Disease and Thalassemia
The scope of this project is to develop in vitro assays to predict response to the therapy with histone deacetylase inhibitors of sick cell and thalassemia patients.