Post-doctoral Fellows

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María Casanova-Acebes

Maria is a postdoctoral fellow from Madrid, Spain. During her PhD, she worked on understanding the aging mechanism in neutrophils and how the removal of these aged PMN by bone marrow macrophages triggers the homeostatic release of hematopoietic progenitors from the bone marrow into the blood. Now in her postdoctoral fellowship in Dr. Merad’s lab, she would like to address the fascinating question of how the peripheral nervous system modulates macrophage phenotype and functions during cancer progression.

Fundings : Human Frontiers Science Program

Contact: maria.casanova-acebes@mssm.edu

Barbara

Barbara Maier

Alveolar macrophages and interstitial macrophages of the lung represent tissue resident populations, that share a core gene expression signature with other macrophage populations, but each have unique transcription profiles. This allows different macrophage populations to be perfectly adapted to their tissue environment and to fulfill tissue specific functions, e.g. clearance of surfactant in the alveolar airspace in the lung. Barbara studies which tissue-derived or cell-intrinsic factors determine macrophage identity at specific tissue sites to better understand how tissues control the homeostatic functions of innate immune cells but at the same time allow for an effective immune response in case of an invading pathogen.

Contact: barbara.b.maier@mssm.edu

 

Jalal Ahmed

 

Contact: jalal.ahmed@mountsinai.org

 

Nausicaa Malissen

Nausicaa  is a MD-PhD, dermato-oncologist from Marseille (France) with an expertise in melanoma . Now, in her postdoctoral fellowship, she will use simultaneous single cell antibody profiling and RNA sequencing (CITE-seq) to profile circulating and tissue resident immune populations in lung adenocarcinoma during anti-PD-1 treatment.
Fundings: Fondation pour la Recherche Médicale, College des Enseignants en Dermatologie de France, Aix-Marseille University

 

Assaf Magen

Assaf Magen, Ph.D. is a computational scientist (bioinformatics) developing computational strategies to mine single-cell genomics and multiplex imaging data of human malignancies. During his doctoral work, he identified novel subsets of immune cells and their prognostic value in murine and human tumors. He is currently working on characterizing the crosstalk between immune, malignant and stromal cells, and how their interactions may affect tumor development and patient response to therapy.

Contact: assaf.magen@mssm.edu

 

Maxime

Maxime Dhainaut

Maxime is a postdoctoral fellow who is part of both the Merad Lab and the Brown Lab. He is taking advantage of the Jedi mice (developed by the Brown laboratory) to study the mechanisms of cytotoxic CD8T cell (CTLs)-mediated tumor regression in vivo. He is particularly interested in the interactions between CTLs and cancer-initiating cells.

Fundings: Belgian American Education Foundation

Contact: maxime.dhainaut@mssm.edu

 

Alfonso Rodriguez

Alfonso is a postdoctoral fellow from Madrid, Spain. During his PhD studies in the University of Navarra (Pamplona, Spain), he investigated the role type 1 conventional dendritic cells play in cancer immunity. In conjunction with Brian Brown’s lab, he is currently working on the development of novel myeloid cell-targeted therapies in the context of cancer immunotherapy.

Contact: alfonso.rodriguez@mssm.edu

 

Gurkan Mollaoglu

Gurkan received his master’s degree in molecular biology and genetics from Koc University (Istanbul, Turkey) and his doctorate in oncological sciences from the University of Utah School of Medicine. He joined the Merad and the Brown labs at Mount Sinai to study the role of cancer genetics in tumor immunity. He is fascinated by the nature of the complex interactions between cancer cells and immune cells. He thinks that a better understanding of the incredibly dynamic co-evolution of cancer cells and the immune system will eventually make most cancers if not all manageable diseases.

Funding: The National Cancer Institute

Contact:gurkan.mollaoglu@mssm.edu

 

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Camille Bigenwald

Camille is an oncologist/hematologist. She completed her hematology advanced fellowship in 2015 and worked at Saint-Louis hospital and Institut Gustave Roussy (Paris, France) in departments with expertise in lymphoid malignancies. She is currently an MD – PhD student, focusing on the tumor microenvironment. She studies the immune mechanisms involved in patients prognostic and response to treatment.

Fundings: Fondation pour la Recherche Médicale

Contact: camille.bigenwald@mssm.edu

 

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Stefan Jordan

Humans evolved in presence of bacteria, viruses and parasites. Stefan studies how the immune system shapes the microbiota inhabiting our body, and how the microbiota shape the immune system. Understanding the underlying mechanisms might lead to new therapies for many diseases, including cancer.

Fundings: German Research Foundation (Deutsche Forschungsgemeinschaft, DFG)

Contact: stefan.jordan@mssm.edu

 

 

 

Jerome Martin

Jerome is a PharmD., PhD. clinical pathologist from Nantes (France). He focused his PhD on the study of IL-22BP, a natural inhibitor of IL-22, and identified it as an important regulator of gut inflammation, especially during inflammatory bowel disease (IBD). He now wants to extend his understanding of IBD inflammation by performing high dimensional analysis using scRNAseq and CyTOF to try to identify cellular and molecular patterns characterizing specific subgroups of patients encompassed within the main IBD phenotypes.

Fundings: Fondation Bettencourt-Schueller

Contact. jerome.martin@mssm.edu