Research

Contact Us

The Senator Frank R. Lautenberg Environmental Health Sciences Laboratory
Atran Building
1428 Madison Avenue, 3rd floor, Room 002
New York, NY 10029
Email: lautenberglab@mssm.edu
Phone: 212 824-7370

Research Areas

Biomarker Development
Elemental Imaging
EpiGenomics
Metals
Organics


Recent Research

Exposure to Specific Toxins and Nutrients During Late Pregnancy and Early Life Shapes Autism Risk
Nature Communications – June 1, 2017
Researchers at the Icahn School of Mount Sinai in New York along with colleagues from the Karolinska Institute in Sweden set out to investigate the contribution to autism risk of specific environmental factors including environmental pollutants (lead, for example) and essential nutritional components of our diet, such as zinc and manganese.

Wild Orangutan Teeth Provide Insight Into Human Breast-Feeding Evolution
Science Advances – May 17, 2017
Tanya Smith, PhD (Griffith); Christine Austin, PhD (Mount Sinai); Manish Arora BDS, PhD (Mount Sinai), and their teams study the maternal milk intake of our primate cousins the orangutans in the hopes to guide our understanding of human breast-feeding evolution and current practices. Orangutan nursing habits have been difficult to study due to challenges in observing this behavior in their natural environment. Using teeth as a biomarker is a novel method to work around these challenges. Due to the ring-like growth pattern of teeth, investigators can determine concentrations of the maternal elements in the infants’ teeth over time.

Research Archive


Research Projects

Our projects integrate innovative and groundbreaking laboratory techniques with population based studies in a highly efficient model that expands the frontiers of children’s medical research.

Major Awards

Epigenetics and Prenatal Programming

Epigenetics is the study of changes in gene expression independent of DNA sequence. Fetal environment is widely believed to be critical to programming later life disease and epigenetics is the likely mechanism behind these observations. The interplay between fetal environment and epigenetics may even explain diseases of adult life.

Neurodevelopment

Increasing rates of neurodevelopmental disorders such as autism spectrum disorder and ADHD in recent years cannot be fully explained by genetics or changing diagnostics. Our studies employ novel techniques and biomarkers to dissect whether environmental exposures during critical periods of brain development lead to dysfunction.

Environmental Pediatrics Training Program

Endocrine Disruptors and Obesity

Childhood obesity is now a worldwide epidemic. While caloric intake is an obvious cause, other not so obvious causes may include environmental exposure that program our appetite or metabolism of food and could lead to increased risk of obesity.

Air Pollution, Stress and Respiratory Health

Our goal is to better understand the how factors in the environment such as stress and exposure to air pollution influence children’s lung growth and development. By identifying windows of susceptibility during pregnancy or childhood we can more efficiently elucidate mechanisms through which these environmental factors affect respiratory health and better inform public health efforts.