Recent Publications

Antigenic sites in influenza H1 hemagglutinin display species-specific immunodominance. Liu STH, Behzadi MA, Sun W, Freyn AW, Liu WC, Broecker F, Albrecht RA, Bouvier NM, Simon V, Nachbagauer R, Krammer F, Palese P. J Clin Invest. 2018 Nov 1. PMID:30188868

Human antibodies targeting Zika virus NS1 provide protection against disease in a mouse model. Bailey MJ, Duehr J, Dulin H, Broecker F, Brown JA, Arumemi FO, Bermúdez González MC, Leyva-Grado VH, Evans MJ, Simon V, Lim JK, Krammer F, Hai R, Palese P, Tan GS. Nat Commun. 2018 Nov 1. PMID:30385750

Antibody responses towards the major antigenic sites of influenza B virus hemagglutinin in mice, ferrets and humans. Sun W, Kang DS, Zheng A, Liu STH, Broecker F, Simon V, Krammer F, Palese P. J Virol. 2018 Oct 31. PMID:30381487

Immunodominance of Antigenic Site B in the Hemagglutinin of the Current H3N2 Influenza Virus in Humans and Mice. Broecker F, Liu STH, Sun W, Krammer F, Simon V, Palese P. J Virol. 2018 Sep 26. PMID:30045991

A Universal Influenza Virus Vaccine Candidate Tested in a Pig Vaccination-Infection Model in the Presence of Maternal Antibodies. Sunwoo SY, Schotsaert M, Morozov I, Davis AS, Li Y, Lee J, McDowell C, Meade P, Nachbagauer R, García-Sastre A, Ma W, Krammer F, Richt JA. Vaccines. 2018 Sep 14. PMID:30223475

Antigenic sites in influenza H1 hemagglutinin display species-specific immunodominance. Liu ST, Behzadi MA, Sun W, Freyn AW, Liu WC, Broecker F, Albrecht RA, Bouvier NM, Simon V, Nachbagauer R, Krammer F, Palese P. J Clin Invest. 2018 Sep 6. PMID:30188868

Nucleoside-modified mRNA immunization elicits influenza virus hemagglutinin stalk-specific antibodies. Pardi N, Parkhouse K, Kirkpatrick E, McMahon M, Zost SJ, Mui BL, Tam YK, Karikó K, Barbosa CJ, Madden TD, Hope MJ, Krammer F, Hensley SE, Weissman D. Nat Comm. 2018 Aug 22. PMID:30135514.

Broadly Reactive Human Monoclonal Antibodies Elicited following Pandemic H1N1 Influenza Virus Exposure Protect Mice against Highly Pathogenic H5N1 Challenge. Nachbagauer R, Shore D, Yang H, Johnson SK, Gabbard JD, Tompkins SM, Wrammert J, Wilson PC, Stevens J, Ahmed R, Krammer F, Ellebedy AH. J Virol. 2018 Jul 31. PMID: 29899095.

A Live-Attenuated Prime, Inactivated Boost Vaccination Strategy with Chimeric Hemagglutinin-Based Universal Influenza Virus Vaccines Provides Protection in Ferrets: A Confirmatory Study.  Nachbagauer R, Krammer F, Albrecht RA. Vaccines. 2018 Jul 25. PMID:30044403.

Immunodominance of Antigenic Site B in the Hemagglutinin of the Current H3N2 Influenza Virus in Humans and Mice. Broecker F, Liu STH, Sun W, Krammer F, Simon V, Palese P. J Virol. 2018 Jul 25. PMID:30045991.

The influenza virus hemagglutinin head evolves faster than the stalk domain. Kirkpatrick E, Qiu X, Wilson PC, Bahl J, Krammer F. Sci Rep. 2018 Jul 11. PMID:29992986.

Influenza. Krammer F, Smith GJD, Fouchier RAM, Peiris M, Kedzierska K, Doherty PC, Palese P, Shaw ML, Treanor J, Webster RG, García-Sastre A. Nat Rev Dis Primers. 2018 Jun 28. PMID:29955068.

Cross-reactive mouse monoclonal antibodies raised against the hemagglutinin of A/Shanghai/1/2013 (H7N9) protect against novel H7 virus isolates in the mouse model. Stadlbauer D, Amanat F, Strohmeier S, Nachbagauer R, Krammer F. Emerg Microbes Infect. 2018 Jun 20. PMID:29925896.

Nucleoside-modified mRNA vaccines induce potent T follicular helper and germinal center B cell responses. Pardi N, Hogan MJ, Naradikian MS, Parkhouse K, Cain DW, Jones L, Moody MA, Verkerke HP, Myles A, Willis E, LaBranche CC, Montefiori DC, Lobby JL, Saunders KO, Liao HX, Korber BT, Sutherland LL, Scearce RM, Hraber PT, Tombácz I, Muramatsu H, Ni H, Balikov DA, Li C, Mui BL, Tam YK, Krammer F, Karikó K, Polacino P, Eisenlohr LC, Madden TD, Hope MJ, Lewis MG, Lee KK, Hu SL, Hensley SE, Cancro MP, Haynes BF, Weissman D. J Exp Med. 2018 Jun 4. PMID:29739835.

Antibodies to the Glycoprotein GP2 Subunit Cross-React between Old and New World Arenaviruses. Amanat F, Duehr J, Oestereich L, Hastie KM, Ollmann Saphire E, Krammer F. mSphere. 2018 May 2. PMID:29720525.

Broadly protective anti-hemagglutinin stalk antibodies induced by live attenuated influenza vaccine expressing chimeric hemagglutinin. Isakova-Sivak I, Korenkov D, Smolonogina T, Kotomina T, Donina S, Matyushenko V, Mezhenskaya D, Krammer F, Rudenko L.Virology. 2018 May 5. PMID:29574336.

Stable incorporation of GM-CSF into dissolvable microneedle patch improves skin vaccination against influenza. Littauer EQ, Mills LK, Brock N, Esser ES, Romanyuk A, Pulit-Penaloza JA, Vassilieva EV, Beaver JT, Antao O, Krammer F, Compans RW, Prausnitz MR, Skountzou I. J Control Release. 2018 Apr 28. PMID:29496540.