Recent Publications

Broadly Reactive Human Monoclonal Antibodies Elicited following Pandemic H1N1 Influenza Virus Exposure Protect Mice against Highly Pathogenic H5N1 Challenge. Nachbagauer R, Shore D, Yang H, Johnson SK, Gabbard JD, Tompkins SM, Wrammert J, Wilson PC, Stevens J, Ahmed R, Krammer F, Ellebedy AH. J Virol. 2018 Jul 31. PMID: 29899095.

A Live-Attenuated Prime, Inactivated Boost Vaccination Strategy with Chimeric Hemagglutinin-Based Universal Influenza Virus Vaccines Provides Protection in Ferrets: A Confirmatory Study.  Nachbagauer R, Krammer F, Albrecht RA. Vaccines. 2018 Jul 25. PMID:30044403.

Immunodominance of Antigenic Site B in the Hemagglutinin of the Current H3N2 Influenza Virus in Humans and Mice. Broecker F, Liu STH, Sun W, Krammer F, Simon V, Palese P. J Virol. 2018 Jul 25. PMID:30045991.

The influenza virus hemagglutinin head evolves faster than the stalk domain. Kirkpatrick E, Qiu X, Wilson PC, Bahl J, Krammer F. Sci Rep. 2018 Jul 11. PMID:29992986.

Influenza. Krammer F, Smith GJD, Fouchier RAM, Peiris M, Kedzierska K, Doherty PC, Palese P, Shaw ML, Treanor J, Webster RG, García-Sastre A. Nat Rev Dis Primers. 2018 Jun 28. PMID:29955068.

Cross-reactive mouse monoclonal antibodies raised against the hemagglutinin of A/Shanghai/1/2013 (H7N9) protect against novel H7 virus isolates in the mouse model. Stadlbauer D, Amanat F, Strohmeier S, Nachbagauer R, Krammer F. Emerg Microbes Infect. 2018 Jun 20. PMID:29925896.

Nucleoside-modified mRNA vaccines induce potent T follicular helper and germinal center B cell responses. Pardi N, Hogan MJ, Naradikian MS, Parkhouse K, Cain DW, Jones L, Moody MA, Verkerke HP, Myles A, Willis E, LaBranche CC, Montefiori DC, Lobby JL, Saunders KO, Liao HX, Korber BT, Sutherland LL, Scearce RM, Hraber PT, Tombácz I, Muramatsu H, Ni H, Balikov DA, Li C, Mui BL, Tam YK, Krammer F, Karikó K, Polacino P, Eisenlohr LC, Madden TD, Hope MJ, Lewis MG, Lee KK, Hu SL, Hensley SE, Cancro MP, Haynes BF, Weissman D. J Exp Med. 2018 Jun 4. PMID:29739835.

Antibodies to the Glycoprotein GP2 Subunit Cross-React between Old and New World Arenaviruses. Amanat F, Duehr J, Oestereich L, Hastie KM, Ollmann Saphire E, Krammer F. mSphere. 2018 May 2. PMID:29720525.

Broadly protective anti-hemagglutinin stalk antibodies induced by live attenuated influenza vaccine expressing chimeric hemagglutinin. Isakova-Sivak I, Korenkov D, Smolonogina T, Kotomina T, Donina S, Matyushenko V, Mezhenskaya D, Krammer F, Rudenko L.Virology. 2018 May 5. PMID:29574336.

Stable incorporation of GM-CSF into dissolvable microneedle patch improves skin vaccination against influenza. Littauer EQ, Mills LK, Brock N, Esser ES, Romanyuk A, Pulit-Penaloza JA, Vassilieva EV, Beaver JT, Antao O, Krammer F, Compans RW, Prausnitz MR, Skountzou I. J Control Release. 2018 Apr 28. PMID:29496540.

Universal influenza virus vaccines and therapeutics: where do we stand with influenza B virus? Tan J, Asthagiri Arunkumar G, Krammer F. Curr Opin Immunol. 2018 Apr 17. PMID:29677684.

Impact of pre-existing immunity on the induction of functional cross-reactive anti-hemagglutinin stalk antibodies following vaccination with an AS03 adjuvanted pandemic H1N1 vaccine. Tete SM, Jul-Larsen Å, Rostami S, Lunde THF, Søland H, Krammer F, Cox RJ. Vaccine. 2018 Apr 12. PMID:29548607.

Broad cross-reactive IgG responses elicited by adjuvanted vaccination with recombinant influenza hemagglutinin (rHA) in ferrets and mice. Wang J, Hilchey SP, DeDiego M, Perry S, Hyrien O, Nogales A, Garigen J, Amanat F, Huertas N, Krammer F, Martinez-Sobrido L, Topham DJ, Treanor JJ, Sangster MY, Zand MS. PLoS One. 2018 Apr 11. PMID:29641537.

Influenza Infection in Humans Induces Broadly Cross-Reactive and Protective Neuraminidase-Reactive Antibodies. Chen YQ, Wohlbold TJ, Zheng NY, Huang M, Huang Y, Neu KE, Lee J, Wan H, Rojas KT, Kirkpatrick E, Henry C, Palm AE, Stamper CT, Lan LY, Topham DJ, Treanor J, Wrammert J, Ahmed R, Eichelberger MC, Georgiou G, Krammer F, Wilson PC. Cell. 2018 Apr 5. PMID:29625056.

An immuno-assay to quantify influenza virus hemagglutinin with correctly folded stalk domains in vaccine preparations. Rajendran M, Sun W, Comella P, Nachbagauer R, Wohlbold TJ, Amanat F, Kirkpatrick E, Palese P, Krammer F. PLoS One. 2018 Apr 4. PMID:29617394.

NAction! How Can Neuraminidase-Based Immunity Contribute to Better Influenza Virus Vaccines? Krammer F, Fouchier RAM, Eichelberger MC, Webby RJ, Shaw-Saliba K, Wan H, Wilson PC, Compans RW, Skountzou I, Monto AS. M Bio. 2018 Apr 3. PMID:29615508.

H5N2 vaccine viruses on Russian and US live attenuated influenza virus backbones demonstrate similar infectivity, immunogenicity and protection in ferrets. Czakó R, Vogel L, Sutton T, Matsuoka Y, Krammer F, Chen Z, Jin H, Subbarao K. Vaccine. 2018 Mar 27. PMID:29503113.

Influenza B virus reverse genetic backbones with improved growth properties in the EB66® cell line as basis for vaccine seed virus generation. White KM, Ayllon J, Mena I, Potenski A, Krammer F, García-Sastre A. Vaccine. 2018 Feb 21. PMID:29395518.

Tick-Borne Encephalitis Virus Vaccine-Induced Human Antibodies Mediate Negligible Enhancement of Zika Virus Infection InVitro and in a Mouse Model. Duehr J, Lee S, Singh G, Foster GA, Krysztof D, Stramer SL, Bermúdez González MC, Menichetti E, Geretschläger R, Gabriel C, Simon V, Lim JK, Krammer F. mSphere. 2018 Feb 7. PMID:29435494.

A full publication list can be found here:

http://www.ncbi.nlm.nih.gov/sites/myncbi/1NwQ0Nsdo2zQD/bibliography/47693335/public/?sort=date&direction=ascending