Congenital heart defects

Congenital heart defects (CHD) are the commonest form of birth defects and, despite remarkable progress in clinical care, remain the class of birth defect with the highest newborn mortality. Moreover, long-term outcomes are not optimal due to co-morbidities and premature mortality.  The Gelb lab is focused on improving care for individuals with CHD and their families by using genetic approaches to understand the fundamental causes of CHD and then using that information to improve outcomes.