Research and Grants

ACTIVE
1.      PI – 3.0 calendar months effort,                         Total direct cost budget: $1,125,000
“A Role of Hypothalamic Dysfunction in Alcoholic Liver Disease”
The major goal is to study a role of hypothalamic dysfunction in alcoholic liver disease
NIH/NIDDK -1 R01 AA023416-01.                           02/01/2014 – 01/31/2019

2.      PI – 2.4 calendar months effort,                         Total direct cost budget: $ 800,000
“Brain insulin as a regulator of Sepsis survival”
The major goal is to define a role of brain insulin as a regulator of innate immunity
Career Development Award 7-11-CD-02                      01/01/2012-12/31/2017

3.      Co-PI – 0.06 calendar months effort,             Total direct cost budget: $ 6,000,000
“Integrative Biology Approach to Complexity of Alzheimer’s Disease”
Goal is to identify gene networks that are shared between Alzheimers and Diabetes.
Mount Sinai School of Medicine 1 UO1 AG046170 01 (Schadt Eric E) 09-20-2013-09-19-2018

4.      Co-PI/Project 2, leader – 2.4calendar months effort Total direct cost budget: $ 1,843,698
“Alzheimers disease and Diabetes”
The goal is to study insulin signaling in several cell types derived from inducible pluripotent stem cells from patients with Alzheimer’s.
NIA, P50 AG 005138 (PI Sano PI)                         01/01/2015-12/31/2019

5.      PI – administrative supplement                   Total direct cost budget: $ 149,903
“A Role of Hypothalamic Dysfunction in Alcoholic Liver Disease”
This is a minority supplement.
NIH/NIDDK -1 R01 AA023416-01S1.                         07/01/2014 – 12/31/2016

6.      Mentor                                            Total direct cost budget: $750,000
“Perinatal Exposure to Environmental DDT and Risk of Metabolic Syndrome”
Here we examine if and through what mechanisms perinatal exposure to DDT increases the metabolic syndrome.
NIH NIEHS – K99/ROO ES019919 (La Merrill)                       08/01/2011-7/31/2016

7.      Mentor                                                  Total direct cost budget: $578,016
“Role of Brain Insulin in the regulation of Branched Chain Amino acid Metabolism”
The goal is to define a role of brain insulin signaling in regulating BCAA catabolism.
NIDKK – 1 K01 DK099463 01 (Shin Andrew)                 09-20-2013-09-19-2017

PREVIOUS GRANT SUPPORT
1.      PI – 0.6 calendar                                       Total direct cost budget: $35,000
“Brain insulin as a regulator of innate immunity.”
Hirschl/Monique Weill-Caulier Trust                     01/01/2010-12/31/2015
2.      PI – 3.36 calendar                                      Total direct cost budget: $240,000
“The regulation of adipose tissue by central insulin and leptin. ”
NIH/NIDKK – R01-0836581                 07/01/2009-06/30/2014
3.      PI – 1.32 calendar                                      Total direct cost budget: $ 120,000